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The map label for this gene is xpt

Identifier: 148379126

GI number: 148379126

Start: 1252271

End: 1252843

Strand: Direct

Name: xpt

Synonym: CBO1139

Alternate gene names: 148379126

Gene position: 1252271-1252843 (Clockwise)

Preceding gene: 148379125

Following gene: 148379127

Centisome position: 32.22

GC content: 26.53

Gene sequence:

>573_bases
ATGAAATTACTAGAAGATAAAATATTAAAAGAGGGTATATTATTAGAAGGAAATATACTTAAAGTAGATAGCTTTTTAAA
TCATCAAATGGATGTAAAGCTATTTAATGAAATTGGAAAAGAATTTAAAAGAAGATTTGAAGGATGTAGCATAAATAAAA
TATTAACTATTGAAGCTTCGGGTATAGGTATTGCTACTATAGTATCTCAATACTTTGATTTTTGTCCTGTGGTTTTTGCT
AAAAAGGTAGATGCAGCAAATATGGACAAAGATACTTATGAATCAAAGGTGCACTCTTTTACTAAAAATAAAACTTATAA
TGTAAGGGTATCTAAAAAATACATAAATAAAGGGGATAAAATACTTTTAATAGATGATTTTTTGGCTAATGGCTGTGCAG
CTTTAGGATTGATAGATATAATAAAGCAAGGAGGAGCAGAACTTATAGGAGTAGGAATTGCTATAGAAAAAGGATTTCAA
AAAGGTAGAAAAGAATTAGAAAAAGTAGGTGCTAAAGTGGAATCTTTAGCTATATTAGATAAAATAGAAAATGATAAAGT
ATATTTTAAATAA

Upstream 100 bases:

>100_bases
TAAGAGAGACAAGTTTAATGTACTATAACTGGAATTACAATTTATAACAATTATATTTAATACAGTATACTTTATGTGGA
AAGGGAAGGAATAAATATTT

Downstream 100 bases:

>100_bases
ATATTAATTTATTGTATCTTAAAAAGCATATTTAGATATTATCAAAAATAAATATAAATTTTAATTGATATGTTAAGAAA
ATGATAAATATGCTCTAATA

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase 2

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MKLLEDKILKEGILLEGNILKVDSFLNHQMDVKLFNEIGKEFKRRFEGCSINKILTIEASGIGIATIVSQYFDFCPVVFA
KKVDAANMDKDTYESKVHSFTKNKTYNVRVSKKYINKGDKILLIDDFLANGCAALGLIDIIKQGGAELIGVGIAIEKGFQ
KGRKELEKVGAKVESLAILDKIENDKVYFK

Sequences:

>Translated_190_residues
MKLLEDKILKEGILLEGNILKVDSFLNHQMDVKLFNEIGKEFKRRFEGCSINKILTIEASGIGIATIVSQYFDFCPVVFA
KKVDAANMDKDTYESKVHSFTKNKTYNVRVSKKYINKGDKILLIDDFLANGCAALGLIDIIKQGGAELIGVGIAIEKGFQ
KGRKELEKVGAKVESLAILDKIENDKVYFK
>Mature_190_residues
MKLLEDKILKEGILLEGNILKVDSFLNHQMDVKLFNEIGKEFKRRFEGCSINKILTIEASGIGIATIVSQYFDFCPVVFA
KKVDAANMDKDTYESKVHSFTKNKTYNVRVSKKYINKGDKILLIDDFLANGCAALGLIDIIKQGGAELIGVGIAIEKGFQ
KGRKELEKVGAKVESLAILDKIENDKVYFK

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XPT2_CLOB1 (A7FT29)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001383506.1
- ProteinModelPortal:   A7FT29
- SMR:   A7FT29
- STRING:   A7FT29
- GeneID:   5397856
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_1176
- eggNOG:   COG0503
- HOGENOM:   HBG288993
- OMA:   QYFNVPV
- ProtClustDB:   PRK09219
- BioCyc:   CBOT441770:CLB_1176-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01184
- InterPro:   IPR000836
- InterPro:   IPR010079
- TIGRFAMs:   TIGR01744

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 21240; Mature: 21240

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 20-20 BINDING 27-27 BINDING 157-157

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLEDKILKEGILLEGNILKVDSFLNHQMDVKLFNEIGKEFKRRFEGCSINKILTIEAS
CCCHHHHHHHCCCEECCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
GIGIATIVSQYFDFCPVVFAKKVDAANMDKDTYESKVHSFTKNKTYNVRVSKKYINKGDK
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEEHHHHCCCCE
ILLIDDFLANGCAALGLIDIIKQGGAELIGVGIAIEKGFQKGRKELEKVGAKVESLAILD
EEEEEHHHHCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KIENDKVYFK
HCCCCCEEEC
>Mature Secondary Structure
MKLLEDKILKEGILLEGNILKVDSFLNHQMDVKLFNEIGKEFKRRFEGCSINKILTIEAS
CCCHHHHHHHCCCEECCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
GIGIATIVSQYFDFCPVVFAKKVDAANMDKDTYESKVHSFTKNKTYNVRVSKKYINKGDK
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEEHHHHCCCCE
ILLIDDFLANGCAALGLIDIIKQGGAELIGVGIAIEKGFQKGRKELEKVGAKVESLAILD
EEEEEHHHHCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KIENDKVYFK
HCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA