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The map label for this gene is resE [H]

Identifier: 148379108

GI number: 148379108

Start: 1229793

End: 1231226

Strand: Direct

Name: resE [H]

Synonym: CBO1120

Alternate gene names: 148379108

Gene position: 1229793-1231226 (Clockwise)

Preceding gene: 148379107

Following gene: 148379110

Centisome position: 31.64

GC content: 21.62

Gene sequence:

>1434_bases
ATGGAAAATATAAGTACTGTAATTATTAAAGAACGACAGGAAGTTATAAAGAAATTTTTACCCATAAGATTTATATTAAT
TAACGCAGTAATTGGTTTTATTTATGTAAGTTATGTTAAATCAGATTTAAAATCGTTTTGTATTTTTAATATTGCAATGG
TAGAGGGAATAATATTCAATAATATGTTGTGTGGATTTTCTAGTAGAGATATGAAAACTTTTAAAAACAAGTTTAATAGT
AAGTATAATAATAAAACAAAAATATATAAAAATTTTATTAATAATATTATTTCACCTATAATAATATTAAAAGATGAAAA
AATTTATTTTATGAATGATGAAGCTAAAAAATATATAAAAATTAAAAAGAATATAAATTTTAATAATATAAATATATATG
ATTATTTAGAAGAAAAATTTTATAAAGAAGGATTATTAAAAATAGATAATATCAAAAATTCTACAGGAATTACCTATTTA
AATGAAAAAATTATTTTAAAAAATGGAGAAATATTAAAGGTAGATTTAAGATGCTTTGTTTTAGACTTAAATGGCGAAGA
GTTTGTAAGTATATCTATTAAGAACAATGTCTTATTACAAGAAAATAAAAAATTATATGAAGAGCTAGAAAAAAACAAAG
TAGAACATAGACAAAGAGCTGAATTTTATGCTAATATATCACATGATTTAAAAACACCTATAAATATTATATATTCTGCT
ATTCAGGTTATGAATATGGCTTTAGACAATAAAAAAATAGATACTATTGAAAAATATATTGGAGTAATAAAACAAAATTG
TTACAGACTTTTAAGACTTGTAAATAATATAGTTAACACCAATAAGATTGAATCCGGATGTTGTAAAATTAAATTAAATA
ATAATAATATAGTTAGTTTAGTTGAAGACATAGTTACATCTGTTTCTACATATGTTGAGAATAATGATATGGATATAATA
TTTGATACAGATACAGAAGAAAAAATTATAGCTTGTGATAAAGATATGATAGAAAGAGTTGTATTAAATCTTATATCAAA
TTCTGTTAAATATAAACAAAAGGGAAAAGGAAGTATACAAGTTACTGTACAAGATAAAGAGGATAGAGTTATTGTTTCTG
TTAAAGATAATGGTATAGGAATACCTGAAAATATACAAAAGAATGTGTTTAATAGATTTGTACAATCAAATAGAAAAGAA
TATGATTTAACAACTTGTAGTAGTGGTATAGGACTTGCTCTAGTTAAATCTATAATTGATATGCATGATGGAAATATTCA
AATAAACAGTAGAGAAAATAAAGGCACAGAGATAATCTTTGAACTTCCTTCTAGGAAGGTTAAAGAAAATGAGAAATGTA
AGGAAATATATACTAAAAATATAGGAAAGAATGTAAAAATTGAATTTCCAGAAATATATGATAGTGCTATTTGA

Upstream 100 bases:

>100_bases
TATTTTAAATTTTAAAACCAATAAAAGGAAAATAATAGAAAATGTTGAATTATTTATATATAAAGTAAAATTATGCAAAT
ATTAAAAGGGGAGTGGGGAA

Downstream 100 bases:

>100_bases
ATAAAGACTTTAAAAGAGTTGTTTTTAGTGATAAAGAGGGCGTTTCAAAATTAAATATATTTTGAAACACCTTCCTTTTA
TTATCTTATCATATAAATTG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MENISTVIIKERQEVIKKFLPIRFILINAVIGFIYVSYVKSDLKSFCIFNIAMVEGIIFNNMLCGFSSRDMKTFKNKFNS
KYNNKTKIYKNFINNIISPIIILKDEKIYFMNDEAKKYIKIKKNINFNNINIYDYLEEKFYKEGLLKIDNIKNSTGITYL
NEKIILKNGEILKVDLRCFVLDLNGEEFVSISIKNNVLLQENKKLYEELEKNKVEHRQRAEFYANISHDLKTPINIIYSA
IQVMNMALDNKKIDTIEKYIGVIKQNCYRLLRLVNNIVNTNKIESGCCKIKLNNNNIVSLVEDIVTSVSTYVENNDMDII
FDTDTEEKIIACDKDMIERVVLNLISNSVKYKQKGKGSIQVTVQDKEDRVIVSVKDNGIGIPENIQKNVFNRFVQSNRKE
YDLTTCSSGIGLALVKSIIDMHDGNIQINSRENKGTEIIFELPSRKVKENEKCKEIYTKNIGKNVKIEFPEIYDSAI

Sequences:

>Translated_477_residues
MENISTVIIKERQEVIKKFLPIRFILINAVIGFIYVSYVKSDLKSFCIFNIAMVEGIIFNNMLCGFSSRDMKTFKNKFNS
KYNNKTKIYKNFINNIISPIIILKDEKIYFMNDEAKKYIKIKKNINFNNINIYDYLEEKFYKEGLLKIDNIKNSTGITYL
NEKIILKNGEILKVDLRCFVLDLNGEEFVSISIKNNVLLQENKKLYEELEKNKVEHRQRAEFYANISHDLKTPINIIYSA
IQVMNMALDNKKIDTIEKYIGVIKQNCYRLLRLVNNIVNTNKIESGCCKIKLNNNNIVSLVEDIVTSVSTYVENNDMDII
FDTDTEEKIIACDKDMIERVVLNLISNSVKYKQKGKGSIQVTVQDKEDRVIVSVKDNGIGIPENIQKNVFNRFVQSNRKE
YDLTTCSSGIGLALVKSIIDMHDGNIQINSRENKGTEIIFELPSRKVKENEKCKEIYTKNIGKNVKIEFPEIYDSAI
>Mature_477_residues
MENISTVIIKERQEVIKKFLPIRFILINAVIGFIYVSYVKSDLKSFCIFNIAMVEGIIFNNMLCGFSSRDMKTFKNKFNS
KYNNKTKIYKNFINNIISPIIILKDEKIYFMNDEAKKYIKIKKNINFNNINIYDYLEEKFYKEGLLKIDNIKNSTGITYL
NEKIILKNGEILKVDLRCFVLDLNGEEFVSISIKNNVLLQENKKLYEELEKNKVEHRQRAEFYANISHDLKTPINIIYSA
IQVMNMALDNKKIDTIEKYIGVIKQNCYRLLRLVNNIVNTNKIESGCCKIKLNNNNIVSLVEDIVTSVSTYVENNDMDII
FDTDTEEKIIACDKDMIERVVLNLISNSVKYKQKGKGSIQVTVQDKEDRVIVSVKDNGIGIPENIQKNVFNRFVQSNRKE
YDLTTCSSGIGLALVKSIIDMHDGNIQINSRENKGTEIIFELPSRKVKENEKCKEIYTKNIGKNVKIEFPEIYDSAI

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=26.6932270916335, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=28.3261802575107, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789149, Length=242, Percent_Identity=23.5537190082645, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1790300, Length=288, Percent_Identity=25.6944444444444, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI48994928, Length=252, Percent_Identity=25.7936507936508, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788549, Length=227, Percent_Identity=26.431718061674, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788713, Length=242, Percent_Identity=24.7933884297521, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788393, Length=250, Percent_Identity=22.4, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1789808, Length=237, Percent_Identity=24.8945147679325, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI145693157, Length=259, Percent_Identity=23.5521235521236, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI87081816, Length=259, Percent_Identity=23.9382239382239, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786783, Length=231, Percent_Identity=25.974025974026, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=24.0343347639485, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790436, Length=253, Percent_Identity=23.3201581027668, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=243, Percent_Identity=22.6337448559671, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788279, Length=242, Percent_Identity=26.4462809917355, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55276; Mature: 55276

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENISTVIIKERQEVIKKFLPIRFILINAVIGFIYVSYVKSDLKSFCIFNIAMVEGIIFN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NMLCGFSSRDMKTFKNKFNSKYNNKTKIYKNFINNIISPIIILKDEKIYFMNDEAKKYIK
HHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCEEEEECCCCEEEEE
IKKNINFNNINIYDYLEEKFYKEGLLKIDNIKNSTGITYLNEKIILKNGEILKVDLRCFV
EECCCCCCCEEHHHHHHHHHHHCCCEEEECCCCCCCEEEECCEEEEECCCEEEEEEEEEE
LDLNGEEFVSISIKNNVLLQENKKLYEELEKNKVEHRQRAEFYANISHDLKTPINIIYSA
EEECCCEEEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
IQVMNMALDNKKIDTIEKYIGVIKQNCYRLLRLVNNIVNTNKIESGCCKIKLNNNNIVSL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHH
VEDIVTSVSTYVENNDMDIIFDTDTEEKIIACDKDMIERVVLNLISNSVKYKQKGKGSIQ
HHHHHHHHHHHHCCCCEEEEEECCCCCCEEECCHHHHHHHHHHHHHCCHHHHHCCCCEEE
VTVQDKEDRVIVSVKDNGIGIPENIQKNVFNRFVQSNRKEYDLTTCSSGIGLALVKSIID
EEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHH
MHDGNIQINSRENKGTEIIFELPSRKVKENEKCKEIYTKNIGKNVKIEFPEIYDSAI
CCCCCEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEECHHHHCCCC
>Mature Secondary Structure
MENISTVIIKERQEVIKKFLPIRFILINAVIGFIYVSYVKSDLKSFCIFNIAMVEGIIFN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NMLCGFSSRDMKTFKNKFNSKYNNKTKIYKNFINNIISPIIILKDEKIYFMNDEAKKYIK
HHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCEEEEECCCCEEEEE
IKKNINFNNINIYDYLEEKFYKEGLLKIDNIKNSTGITYLNEKIILKNGEILKVDLRCFV
EECCCCCCCEEHHHHHHHHHHHCCCEEEECCCCCCCEEEECCEEEEECCCEEEEEEEEEE
LDLNGEEFVSISIKNNVLLQENKKLYEELEKNKVEHRQRAEFYANISHDLKTPINIIYSA
EEECCCEEEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
IQVMNMALDNKKIDTIEKYIGVIKQNCYRLLRLVNNIVNTNKIESGCCKIKLNNNNIVSL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHH
VEDIVTSVSTYVENNDMDIIFDTDTEEKIIACDKDMIERVVLNLISNSVKYKQKGKGSIQ
HHHHHHHHHHHHCCCCEEEEEECCCCCCEEECCHHHHHHHHHHHHHCCHHHHHCCCCEEE
VTVQDKEDRVIVSVKDNGIGIPENIQKNVFNRFVQSNRKEYDLTTCSSGIGLALVKSIID
EEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHH
MHDGNIQINSRENKGTEIIFELPSRKVKENEKCKEIYTKNIGKNVKIEFPEIYDSAI
CCCCCEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEECHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]