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The map label for this gene is gap2 [H]

Identifier: 148379083

GI number: 148379083

Start: 1204432

End: 1205448

Strand: Direct

Name: gap2 [H]

Synonym: CBO1095

Alternate gene names: 148379083

Gene position: 1204432-1205448 (Clockwise)

Preceding gene: 148379081

Following gene: 148379085

Centisome position: 30.99

GC content: 31.96

Gene sequence:

>1017_bases
ATGGGTATAAAAGTTGGACTAAATGGTTTTGGAAGAATAGGAAGAGCAGTATTAAGAATAGCACAGGACAAGTTCCCAGA
AGATGTAGAAATAGTAGCATTAAATGCGAGAGCCACTACTGAAACATTAGTACATCTATTTAAATACGACTCCTGCTACG
GAAGATTTAATGGACAAGTGGAAATAATCTCTAATGATAATATGAAAGTAAATGGAAAAGAAATAAAAATATTTAGAGAA
AATGATCCTCAAAATTTACCGTGGAAAGAACTTGGAGTAGATATAGTTATAGAATCTACAGGGATATTTAAAGATAGAGA
AAAAGCTATGAAGCATATAGAAGCTGGAGCTAAAAAAGTTATAATAACAGCACCAGGAAAAAATGAAGATATAACTATAG
TTTTAGGAGTAAATGAAAATGAATATAATCCAGAAGAGCATAATATAATTTCAAATGCATCTTGTACTACAAATTGTTTA
GCTCCTTTTGCTAAAGTACTTGACGATAATTTTGGTATAGTTAGAGGTTTAATGACAACAGTACATTCTTATACAAATGA
CCAAAGAATATTAGATAAAACTCATAAAGATTTAAGAAGGGCAAGAGCTGCAGGAGAGTCAATAATACCAACTACTACAG
GAGCTGCAAAGGCAGTAGCTAAAGTATTACCTAGTCTTAAAGGTAAATTAAATGGATTTGCTTTAAGAGTTCCGACCCCA
ACAGTATCTTTAACAGATTTAGTTTGTGAATTAAAAACTAAAGTAACTGCTGAAGAAATTAATGCAGCGTTTAAAAAAGC
AGCAGATGGCGAAATGAAGGGTGTTTTAGGATATTCAGAAGAACCACTAGTTTCAGTAGATTACAAGGGAGATCCAAGAT
CCTCTATAGTGGATGGATTATCTACTATGGTTTTAGAAGACGATATGGTTAAAGTTGTGTCTTGGTATGATAATGAATGG
GGATACTCATGTAGAACTGTAGATTTAGTTAATTATGTAGCTAAATTTATGAAATAA

Upstream 100 bases:

>100_bases
ATATAATAAGGAATCATACAACACATATATTAATTTAATGAATTATAAATAAAGTATTTTAAAGATTATTTAAATAATAT
ATTAATAGGGGGAAAAAACA

Downstream 100 bases:

>100_bases
AAATAATTAATTAGCTTATATAAATTAATTATATATGAATTAATTTTATATATAAGTACCTCTTTTATAAAATAATTATT
TATATTTATAATAACTTTAG

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MGIKVGLNGFGRIGRAVLRIAQDKFPEDVEIVALNARATTETLVHLFKYDSCYGRFNGQVEIISNDNMKVNGKEIKIFRE
NDPQNLPWKELGVDIVIESTGIFKDREKAMKHIEAGAKKVIITAPGKNEDITIVLGVNENEYNPEEHNIISNASCTTNCL
APFAKVLDDNFGIVRGLMTTVHSYTNDQRILDKTHKDLRRARAAGESIIPTTTGAAKAVAKVLPSLKGKLNGFALRVPTP
TVSLTDLVCELKTKVTAEEINAAFKKAADGEMKGVLGYSEEPLVSVDYKGDPRSSIVDGLSTMVLEDDMVKVVSWYDNEW
GYSCRTVDLVNYVAKFMK

Sequences:

>Translated_338_residues
MGIKVGLNGFGRIGRAVLRIAQDKFPEDVEIVALNARATTETLVHLFKYDSCYGRFNGQVEIISNDNMKVNGKEIKIFRE
NDPQNLPWKELGVDIVIESTGIFKDREKAMKHIEAGAKKVIITAPGKNEDITIVLGVNENEYNPEEHNIISNASCTTNCL
APFAKVLDDNFGIVRGLMTTVHSYTNDQRILDKTHKDLRRARAAGESIIPTTTGAAKAVAKVLPSLKGKLNGFALRVPTP
TVSLTDLVCELKTKVTAEEINAAFKKAADGEMKGVLGYSEEPLVSVDYKGDPRSSIVDGLSTMVLEDDMVKVVSWYDNEW
GYSCRTVDLVNYVAKFMK
>Mature_337_residues
GIKVGLNGFGRIGRAVLRIAQDKFPEDVEIVALNARATTETLVHLFKYDSCYGRFNGQVEIISNDNMKVNGKEIKIFREN
DPQNLPWKELGVDIVIESTGIFKDREKAMKHIEAGAKKVIITAPGKNEDITIVLGVNENEYNPEEHNIISNASCTTNCLA
PFAKVLDDNFGIVRGLMTTVHSYTNDQRILDKTHKDLRRARAAGESIIPTTTGAAKAVAKVLPSLKGKLNGFALRVPTPT
VSLTDLVCELKTKVTAEEINAAFKKAADGEMKGVLGYSEEPLVSVDYKGDPRSSIVDGLSTMVLEDDMVKVVSWYDNEWG
YSCRTVDLVNYVAKFMK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=333, Percent_Identity=50.4504504504504, Blast_Score=337, Evalue=8e-93,
Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=48.8023952095808, Blast_Score=313, Evalue=1e-85,
Organism=Escherichia coli, GI1788079, Length=336, Percent_Identity=53.2738095238095, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1789295, Length=330, Percent_Identity=44.2424242424242, Blast_Score=301, Evalue=3e-83,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=49.7041420118343, Blast_Score=330, Evalue=8e-91,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=50, Blast_Score=329, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=50.4451038575668, Blast_Score=320, Evalue=6e-88,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=50.4451038575668, Blast_Score=320, Evalue=6e-88,
Organism=Saccharomyces cerevisiae, GI6322468, Length=335, Percent_Identity=53.134328358209, Blast_Score=345, Evalue=7e-96,
Organism=Saccharomyces cerevisiae, GI6321631, Length=335, Percent_Identity=53.4328358208955, Blast_Score=343, Evalue=2e-95,
Organism=Saccharomyces cerevisiae, GI6322409, Length=335, Percent_Identity=51.044776119403, Blast_Score=341, Evalue=9e-95,
Organism=Drosophila melanogaster, GI17933600, Length=332, Percent_Identity=49.0963855421687, Blast_Score=318, Evalue=5e-87,
Organism=Drosophila melanogaster, GI18110149, Length=332, Percent_Identity=49.0963855421687, Blast_Score=318, Evalue=5e-87,
Organism=Drosophila melanogaster, GI85725000, Length=332, Percent_Identity=49.3975903614458, Blast_Score=317, Evalue=9e-87,
Organism=Drosophila melanogaster, GI22023983, Length=332, Percent_Identity=49.3975903614458, Blast_Score=317, Evalue=9e-87,
Organism=Drosophila melanogaster, GI19922412, Length=330, Percent_Identity=47.5757575757576, Blast_Score=301, Evalue=3e-82,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37289; Mature: 37158

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIKVGLNGFGRIGRAVLRIAQDKFPEDVEIVALNARATTETLVHLFKYDSCYGRFNGQV
CCEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHCHHCCCCCEE
EIISNDNMKVNGKEIKIFRENDPQNLPWKELGVDIVIESTGIFKDREKAMKHIEAGAKKV
EEEECCCEEECCCEEEEEECCCCCCCCHHHCCEEEEEECCCCCHHHHHHHHHHHCCCCEE
IITAPGKNEDITIVLGVNENEYNPEEHNIISNASCTTNCLAPFAKVLDDNFGIVRGLMTT
EEECCCCCCCEEEEEECCCCCCCCHHHCEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
VHSYTNDQRILDKTHKDLRRARAAGESIIPTTTGAAKAVAKVLPSLKGKLNGFALRVPTP
HHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCC
TVSLTDLVCELKTKVTAEEINAAFKKAADGEMKGVLGYSEEPLVSVDYKGDPRSSIVDGL
CCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEECCCCCCCEEEEECCCCCHHHHHHHH
STMVLEDDMVKVVSWYDNEWGYSCRTVDLVNYVAKFMK
HHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCC
>Mature Secondary Structure 
GIKVGLNGFGRIGRAVLRIAQDKFPEDVEIVALNARATTETLVHLFKYDSCYGRFNGQV
CEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHCHHCCCCCEE
EIISNDNMKVNGKEIKIFRENDPQNLPWKELGVDIVIESTGIFKDREKAMKHIEAGAKKV
EEEECCCEEECCCEEEEEECCCCCCCCHHHCCEEEEEECCCCCHHHHHHHHHHHCCCCEE
IITAPGKNEDITIVLGVNENEYNPEEHNIISNASCTTNCLAPFAKVLDDNFGIVRGLMTT
EEECCCCCCCEEEEEECCCCCCCCHHHCEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
VHSYTNDQRILDKTHKDLRRARAAGESIIPTTTGAAKAVAKVLPSLKGKLNGFALRVPTP
HHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCC
TVSLTDLVCELKTKVTAEEINAAFKKAADGEMKGVLGYSEEPLVSVDYKGDPRSSIVDGL
CCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEECCCCCCCEEEEECCCCCHHHHHHHH
STMVLEDDMVKVVSWYDNEWGYSCRTVDLVNYVAKFMK
HHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2684782; 2227448; 2656407; 7408868; 193030; 3586018; 9175858 [H]