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The map label for this gene is yyaL [H]

Identifier: 148379048

GI number: 148379048

Start: 1165137

End: 1167179

Strand: Direct

Name: yyaL [H]

Synonym: CBO1058

Alternate gene names: 148379048

Gene position: 1165137-1167179 (Clockwise)

Preceding gene: 148379047

Following gene: 148379049

Centisome position: 29.98

GC content: 28.39

Gene sequence:

>2043_bases
ATGAACCTAACAAGTACGAATAGATTAATAAATGAGAAATCCCCTTATTTACTTCAACATGCTCATAATCCAGTAGATTG
GTATCCTTGGGGAGAAGAAGCTTTTGAAAAAGCAAAGATAGAGGATAAGCCTGTATTTTTAAGTATAGGTTATTCTACCT
GTCATTGGTGCCATGTTATGGAAAGAGAGTCCTTTGAGGATGAGGAAGTTGCGGAAGTTTTAAATAAGAACTTTATTTCT
ATAAAGGTAGATAGAGAAGAAAGACCAGATATAGATAGTATATATATGAATTTTTGTCAGGCTTATACTGGTAGTGGTGG
ATGGCCTTTAACTATAATTATGACTCCAGATAAAAAGCCCTTTTTTGCAGGTACTTATTTCCCAAAATGGGGAAAGTACA
ATGTACCTGGAATTATGGATATTTTAAGATCTATAAGTAATCTTTGGAGAGAAGATAAAAATAAAATATTAGAATCCAGT
AATAGAATATTAGAGCAAATAGAAAGATTTCAAGATAATCATAGACAAGGTGAACTTGAAGAATATATTATTGAAGAAGC
CGCTCAGACTCTACTAGATAATTTTGATAGCAAATATGGTGGCTTTGGTACAAAACCTAAATTTCCTACAGCTCATTACA
TATTATTTTTATTAAGGTACTATTATTTTAAAAAGGATGAAAAAGTGTTAGATGTTATAAATAAAACCTTAACTAGTATG
TATAAAGGTGGCATATTTGATCATATAGGTTTTGGATTTTCAAGATATTCTACAGATAATAAGTGGCTTGTACCTCACTT
TGAAAAGATGCTTTATGATAATGCACTCTTATCTATGGCTTATACAGAAGCTTATGAAGCTACAAAGAATCCATTATTTA
AAGATATAACAGAAAAAGTATTAAACTATGTAAAAAAATCCATGACTTCTGAAAAGGGAGGGTTTTATTCTGCGGAGGAT
GCAGATTCTGAAGGGGTAGAAGGGAAATTTTATTTATGGACTAAAGAAGAAATAATGGATATTTTAGGTGAGGAAGAAGG
GGAACTTTACTGTAAGATTTATGATATAACATCTAAAGGAAATTTTGAGAATAAAAATATAGCTAATCTTATAAATACAG
ACTTAAAGATTGTAGATAATAATAAAGATAAATTAGAAAAAATTAGAGAAAAGTTATTTGAATACAGAGAAAAAAGAATA
CATCCCTATAAAGATGATAAAATACTAACCTCATGGAATGCTTTAATGATAGTAGCTTTTTCTAAGGCTGGGAGAAGTCT
AAAAAATGATAATTATATAGAGATAGCAAAAAAATCAGCAAATTTTATAATAGAAAACCTAATGGATGAAAAAGGTACAT
TATATGCAAGAATTAGAGAGGGAGAAAGAGGTAATGAAGGGTTTATAGATGATTACGCTTTCTTTTTATGGGCACTTATA
GAATTATATGAAGCAAGTTTTGATATTTATTATTTAGAAAAATCTATAGAAGTTGCTAATAGTATGATAGATTTATTTTG
GCATAAAGAGGATGGTGGATTTTATCTATACAGTAAAAATAGTGAAAAACTTTTAGTAAGACCAAAGGAAATCTATGATG
GGGCTACGCCATCAGGAAATGCTGTAGCATCTTTAACATTGAATTTACTTTACTATATTACAGGAGAGGATAGATATAAA
GATTTGGTGGATAAGCAATTTAAGTTTTTTGCAACAAATATAAAAAGTGGACCAATGTATCACTTATTTTCTGTAATAGC
TTATATGTATAATATATCACCTGTAAAGGAAATAACATTAGCTTATAATAAAAAAGATGAAGATTTCTATAAGTTTATAA
ATGAAGTAAATAATAGATATATACCTTTTTCAATAGTAACCTTAAATGATAAAAGTAATGAAATAGAGAAAATAAATAAA
AATATTAAAGATAAAATTGCTATAAAAGATAAAACTACAGTTTATATATGCCAAAATTACGCCTGCAGAGAACCTATAAC
AGATTTGGAAGAATTTAAATCTTTACTATCTACTGATTCTTAG

Upstream 100 bases:

>100_bases
CTCATCCATTCTTTTTTTGTTGCTTTTTTATTTTAAGGGGAGTTAAAGAAATTTTACTGGGTATACTAATTTTATTAATA
AATTTTAAGAAGGTGTTTTT

Downstream 100 bases:

>100_bases
GAATAGTAAAGAAACACTTACAGAGTATATATTTGAATCATTGAGGTATATGGTTATGATATAAATAAATATAAAAAACA
TACGGGAAGTTATGGTAGAA

Product: hypothetical protein

Products: ADP; dTDP

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MNLTSTNRLINEKSPYLLQHAHNPVDWYPWGEEAFEKAKIEDKPVFLSIGYSTCHWCHVMERESFEDEEVAEVLNKNFIS
IKVDREERPDIDSIYMNFCQAYTGSGGWPLTIIMTPDKKPFFAGTYFPKWGKYNVPGIMDILRSISNLWREDKNKILESS
NRILEQIERFQDNHRQGELEEYIIEEAAQTLLDNFDSKYGGFGTKPKFPTAHYILFLLRYYYFKKDEKVLDVINKTLTSM
YKGGIFDHIGFGFSRYSTDNKWLVPHFEKMLYDNALLSMAYTEAYEATKNPLFKDITEKVLNYVKKSMTSEKGGFYSAED
ADSEGVEGKFYLWTKEEIMDILGEEEGELYCKIYDITSKGNFENKNIANLINTDLKIVDNNKDKLEKIREKLFEYREKRI
HPYKDDKILTSWNALMIVAFSKAGRSLKNDNYIEIAKKSANFIIENLMDEKGTLYARIREGERGNEGFIDDYAFFLWALI
ELYEASFDIYYLEKSIEVANSMIDLFWHKEDGGFYLYSKNSEKLLVRPKEIYDGATPSGNAVASLTLNLLYYITGEDRYK
DLVDKQFKFFATNIKSGPMYHLFSVIAYMYNISPVKEITLAYNKKDEDFYKFINEVNNRYIPFSIVTLNDKSNEIEKINK
NIKDKIAIKDKTTVYICQNYACREPITDLEEFKSLLSTDS

Sequences:

>Translated_680_residues
MNLTSTNRLINEKSPYLLQHAHNPVDWYPWGEEAFEKAKIEDKPVFLSIGYSTCHWCHVMERESFEDEEVAEVLNKNFIS
IKVDREERPDIDSIYMNFCQAYTGSGGWPLTIIMTPDKKPFFAGTYFPKWGKYNVPGIMDILRSISNLWREDKNKILESS
NRILEQIERFQDNHRQGELEEYIIEEAAQTLLDNFDSKYGGFGTKPKFPTAHYILFLLRYYYFKKDEKVLDVINKTLTSM
YKGGIFDHIGFGFSRYSTDNKWLVPHFEKMLYDNALLSMAYTEAYEATKNPLFKDITEKVLNYVKKSMTSEKGGFYSAED
ADSEGVEGKFYLWTKEEIMDILGEEEGELYCKIYDITSKGNFENKNIANLINTDLKIVDNNKDKLEKIREKLFEYREKRI
HPYKDDKILTSWNALMIVAFSKAGRSLKNDNYIEIAKKSANFIIENLMDEKGTLYARIREGERGNEGFIDDYAFFLWALI
ELYEASFDIYYLEKSIEVANSMIDLFWHKEDGGFYLYSKNSEKLLVRPKEIYDGATPSGNAVASLTLNLLYYITGEDRYK
DLVDKQFKFFATNIKSGPMYHLFSVIAYMYNISPVKEITLAYNKKDEDFYKFINEVNNRYIPFSIVTLNDKSNEIEKINK
NIKDKIAIKDKTTVYICQNYACREPITDLEEFKSLLSTDS
>Mature_680_residues
MNLTSTNRLINEKSPYLLQHAHNPVDWYPWGEEAFEKAKIEDKPVFLSIGYSTCHWCHVMERESFEDEEVAEVLNKNFIS
IKVDREERPDIDSIYMNFCQAYTGSGGWPLTIIMTPDKKPFFAGTYFPKWGKYNVPGIMDILRSISNLWREDKNKILESS
NRILEQIERFQDNHRQGELEEYIIEEAAQTLLDNFDSKYGGFGTKPKFPTAHYILFLLRYYYFKKDEKVLDVINKTLTSM
YKGGIFDHIGFGFSRYSTDNKWLVPHFEKMLYDNALLSMAYTEAYEATKNPLFKDITEKVLNYVKKSMTSEKGGFYSAED
ADSEGVEGKFYLWTKEEIMDILGEEEGELYCKIYDITSKGNFENKNIANLINTDLKIVDNNKDKLEKIREKLFEYREKRI
HPYKDDKILTSWNALMIVAFSKAGRSLKNDNYIEIAKKSANFIIENLMDEKGTLYARIREGERGNEGFIDDYAFFLWALI
ELYEASFDIYYLEKSIEVANSMIDLFWHKEDGGFYLYSKNSEKLLVRPKEIYDGATPSGNAVASLTLNLLYYITGEDRYK
DLVDKQFKFFATNIKSGPMYHLFSVIAYMYNISPVKEITLAYNKKDEDFYKFINEVNNRYIPFSIVTLNDKSNEIEKINK
NIKDKIAIKDKTTVYICQNYACREPITDLEEFKSLLSTDS

Specific function: Unknown

COG id: COG1331

COG function: function code O; Highly conserved protein containing a thioredoxin domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To C.elegans B0495.5 [H]

Homologues:

Organism=Homo sapiens, GI31542723, Length=723, Percent_Identity=36.3762102351314, Blast_Score=491, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI25147430, Length=725, Percent_Identity=35.7241379310345, Blast_Score=430, Evalue=1e-120,
Organism=Drosophila melanogaster, GI20129985, Length=724, Percent_Identity=37.5690607734807, Blast_Score=478, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008928
- InterPro:   IPR012341
- InterPro:   IPR010819
- InterPro:   IPR004879
- InterPro:   IPR005198
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03190 DUF255; PF07221 GlcNAc_2-epim; PF03663 Glyco_hydro_76 [H]

EC number: 2.7.4.9

Molecular weight: Translated: 79579; Mature: 79579

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTSTNRLINEKSPYLLQHAHNPVDWYPWGEEAFEKAKIEDKPVFLSIGYSTCHWCHVM
CCCCCCHHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCHHHHHHHH
ERESFEDEEVAEVLNKNFISIKVDREERPDIDSIYMNFCQAYTGSGGWPLTIIMTPDKKP
HHCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
FFAGTYFPKWGKYNVPGIMDILRSISNLWREDKNKILESSNRILEQIERFQDNHRQGELE
CEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EYIIEEAAQTLLDNFDSKYGGFGTKPKFPTAHYILFLLRYYYFKKDEKVLDVINKTLTSM
HHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
YKGGIFDHIGFGFSRYSTDNKWLVPHFEKMLYDNALLSMAYTEAYEATKNPLFKDITEKV
HCCCCHHHHCCCHHEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LNYVKKSMTSEKGGFYSAEDADSEGVEGKFYLWTKEEIMDILGEEEGELYCKIYDITSKG
HHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEEEEECCC
NFENKNIANLINTDLKIVDNNKDKLEKIREKLFEYREKRIHPYKDDKILTSWNALMIVAF
CCCCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEEEEEE
SKAGRSLKNDNYIEIAKKSANFIIENLMDEKGTLYARIREGERGNEGFIDDYAFFLWALI
HHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
ELYEASFDIYYLEKSIEVANSMIDLFWHKEDGGFYLYSKNSEKLLVRPKEIYDGATPSGN
HHHHCCCEEEEEHHHHHHHHHHHHHEEEECCCCEEEEECCCCEEEECCHHHHCCCCCCCC
AVASLTLNLLYYITGEDRYKDLVDKQFKFFATNIKSGPMYHLFSVIAYMYNISPVKEITL
HHHEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHE
AYNKKDEDFYKFINEVNNRYIPFSIVTLNDKSNEIEKINKNIKDKIAIKDKTTVYICQNY
EECCCCHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHCCHHHEEEECCCCEEEEECCC
ACREPITDLEEFKSLLSTDS
CCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLTSTNRLINEKSPYLLQHAHNPVDWYPWGEEAFEKAKIEDKPVFLSIGYSTCHWCHVM
CCCCCCHHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCHHHHHHHH
ERESFEDEEVAEVLNKNFISIKVDREERPDIDSIYMNFCQAYTGSGGWPLTIIMTPDKKP
HHCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
FFAGTYFPKWGKYNVPGIMDILRSISNLWREDKNKILESSNRILEQIERFQDNHRQGELE
CEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EYIIEEAAQTLLDNFDSKYGGFGTKPKFPTAHYILFLLRYYYFKKDEKVLDVINKTLTSM
HHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
YKGGIFDHIGFGFSRYSTDNKWLVPHFEKMLYDNALLSMAYTEAYEATKNPLFKDITEKV
HCCCCHHHHCCCHHEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LNYVKKSMTSEKGGFYSAEDADSEGVEGKFYLWTKEEIMDILGEEEGELYCKIYDITSKG
HHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEEEEECCC
NFENKNIANLINTDLKIVDNNKDKLEKIREKLFEYREKRIHPYKDDKILTSWNALMIVAF
CCCCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEEEEEE
SKAGRSLKNDNYIEIAKKSANFIIENLMDEKGTLYARIREGERGNEGFIDDYAFFLWALI
HHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
ELYEASFDIYYLEKSIEVANSMIDLFWHKEDGGFYLYSKNSEKLLVRPKEIYDGATPSGN
HHHHCCCEEEEEHHHHHHHHHHHHHEEEECCCCEEEEECCCCEEEECCHHHHCCCCCCCC
AVASLTLNLLYYITGEDRYKDLVDKQFKFFATNIKSGPMYHLFSVIAYMYNISPVKEITL
HHHEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHE
AYNKKDEDFYKFINEVNNRYIPFSIVTLNDKSNEIEKINKNIKDKIAIKDKTTVYICQNY
EECCCCHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHCCHHHEEEECCCCEEEEECCC
ACREPITDLEEFKSLLSTDS
CCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dTMP

Specific reaction: ATP + dTMP = ADP + dTDP

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]