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The map label for this gene is resE [H]

Identifier: 148379026

GI number: 148379026

Start: 1136205

End: 1137560

Strand: Direct

Name: resE [H]

Synonym: CBO1036

Alternate gene names: 148379026

Gene position: 1136205-1137560 (Clockwise)

Preceding gene: 148379025

Following gene: 148379027

Centisome position: 29.23

GC content: 27.95

Gene sequence:

>1356_bases
GTGCATACAATAAGAAAAAGATTAAGTATTTTATTTGTTATTTGCTCAGTAGCAGGAATATTGCTTGTTACATTGTTTGT
AAATGCAACTATAAATAATAAATTTGATGCATATATAGTGGATGTCCAAGATAAAAGATATCAAAGAATAGTATCTTACT
TTGAAGAAGTATATAAAGCACAAGGAAAGTGGACTAAAAATTCTGGTGTTGAGTTGATGCATGAAGCTCATATGGGAAAT
TATTGTTTAACACTTCTAGATATTAATAAAAAAACTATATGGGGTATGAACCCAAATGATATAAGATTAAATACAATGCC
TGTAAAGGATAGAGGTGTTTATAATACTAAGACTTTTGAAATTAAATCAGAAGGTAAAGTAGTTGGATATGTGGGGATTG
GACAGTATTCCTCTTTACTATTATCTGAAGAAGATATAAGTTTTAAAACATCTATAAATAAAAGTATTGTTGCTAGTGGA
ATTCTAACTCTTGTTATTATAATTACCATAAGTCTTTACTTTTCCAAACAATTCTCAATTCCAATTAAGGAGGTTGCTAA
TTTGTCTGTAAATTTATCAAAAGGAGATTTTGATGGGAAATCAAGCGTTGAAAGTAATATTGAAGAACTAGAGAATTTAA
GAAAAAGTGTTAATATATTAGCTGAAAAATTAAAGCATCAAGATTCTATAAGAAGAAGATTAGTTTCTGACATATCCCAT
GAGATCAGAACTCCATTAAATGTATTGCAAAATAACCTAGAGGCAATGATAGATGGAGTTTTACCTGTTACAGAAGAAAG
ATTAAATTGTCTGAATGAAGAAGTAGTTAGATTTGGTAGATTATTAAATAACTTAAATGTATTAAAAGAGTTTGAATCTG
AGAGTATTAAGCTTAATTTCCAAAAAATATTTTTAGATGAATTAATTGCAGATATATGTAGTGATTTTTATGCAATAGCG
GAAAACAAGAATATTAAACTGCAATACCATATAGAAAATCATGAGGATTATAGTATAACTGGAGATAGAGATAGATTAAA
ACAAGTATTTATAAATTTACTTTCTAATGCTCTTAAATTTACAGAAGATGGCGGAGAAGTACTAATTAAAATATATAAAA
GTGATAAAAACATTGTTGTAGAAGTTAAGGATAATGGTGTAGGAATTAAGAAGGAAGATTTGCCTTTTATATTTGAGAGA
CTTTATAGGGGAGATAAGAGTAGACACCAATTTAAAGGGAATGGTATAGGGTTAACTATTGTGAAAAATATATTGCAGCT
CCATTATGCAAGTATAGATCTTGAAAGTGAAGAAGGTGAAGGAACTACTTTTAAGGTCTATTTTCATAGAATGTAA

Upstream 100 bases:

>100_bases
TATAAAGAATATTCGTAAAAAGATAGAAGAAGATACTAAGAATCCTAAATATATTGTTACAGTTATGAAGGTAGGTTATA
AATTTGGTGGTGAAAATTAA

Downstream 100 bases:

>100_bases
ATAACTAATAAAAGTATAAATAAATTTTAGAAGTATTATGGAGGAATGAGAGATCCTTAAATTATAAAGTATTATTCAAA
AACACGTTTGGGGGAAGTAT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MHTIRKRLSILFVICSVAGILLVTLFVNATINNKFDAYIVDVQDKRYQRIVSYFEEVYKAQGKWTKNSGVELMHEAHMGN
YCLTLLDINKKTIWGMNPNDIRLNTMPVKDRGVYNTKTFEIKSEGKVVGYVGIGQYSSLLLSEEDISFKTSINKSIVASG
ILTLVIIITISLYFSKQFSIPIKEVANLSVNLSKGDFDGKSSVESNIEELENLRKSVNILAEKLKHQDSIRRRLVSDISH
EIRTPLNVLQNNLEAMIDGVLPVTEERLNCLNEEVVRFGRLLNNLNVLKEFESESIKLNFQKIFLDELIADICSDFYAIA
ENKNIKLQYHIENHEDYSITGDRDRLKQVFINLLSNALKFTEDGGEVLIKIYKSDKNIVVEVKDNGVGIKKEDLPFIFER
LYRGDKSRHQFKGNGIGLTIVKNILQLHYASIDLESEEGEGTTFKVYFHRM

Sequences:

>Translated_451_residues
MHTIRKRLSILFVICSVAGILLVTLFVNATINNKFDAYIVDVQDKRYQRIVSYFEEVYKAQGKWTKNSGVELMHEAHMGN
YCLTLLDINKKTIWGMNPNDIRLNTMPVKDRGVYNTKTFEIKSEGKVVGYVGIGQYSSLLLSEEDISFKTSINKSIVASG
ILTLVIIITISLYFSKQFSIPIKEVANLSVNLSKGDFDGKSSVESNIEELENLRKSVNILAEKLKHQDSIRRRLVSDISH
EIRTPLNVLQNNLEAMIDGVLPVTEERLNCLNEEVVRFGRLLNNLNVLKEFESESIKLNFQKIFLDELIADICSDFYAIA
ENKNIKLQYHIENHEDYSITGDRDRLKQVFINLLSNALKFTEDGGEVLIKIYKSDKNIVVEVKDNGVGIKKEDLPFIFER
LYRGDKSRHQFKGNGIGLTIVKNILQLHYASIDLESEEGEGTTFKVYFHRM
>Mature_451_residues
MHTIRKRLSILFVICSVAGILLVTLFVNATINNKFDAYIVDVQDKRYQRIVSYFEEVYKAQGKWTKNSGVELMHEAHMGN
YCLTLLDINKKTIWGMNPNDIRLNTMPVKDRGVYNTKTFEIKSEGKVVGYVGIGQYSSLLLSEEDISFKTSINKSIVASG
ILTLVIIITISLYFSKQFSIPIKEVANLSVNLSKGDFDGKSSVESNIEELENLRKSVNILAEKLKHQDSIRRRLVSDISH
EIRTPLNVLQNNLEAMIDGVLPVTEERLNCLNEEVVRFGRLLNNLNVLKEFESESIKLNFQKIFLDELIADICSDFYAIA
ENKNIKLQYHIENHEDYSITGDRDRLKQVFINLLSNALKFTEDGGEVLIKIYKSDKNIVVEVKDNGVGIKKEDLPFIFER
LYRGDKSRHQFKGNGIGLTIVKNILQLHYASIDLESEEGEGTTFKVYFHRM

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=255, Percent_Identity=34.9019607843137, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786783, Length=296, Percent_Identity=27.7027027027027, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=31.8385650224215, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI145693157, Length=236, Percent_Identity=27.1186440677966, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=28.6307053941909, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1788713, Length=251, Percent_Identity=29.8804780876494, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789149, Length=259, Percent_Identity=23.9382239382239, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790346, Length=295, Percent_Identity=25.0847457627119, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87082128, Length=291, Percent_Identity=23.0240549828179, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789403, Length=313, Percent_Identity=25.8785942492013, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=27.0386266094421, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790551, Length=299, Percent_Identity=26.7558528428094, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787894, Length=288, Percent_Identity=25, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786912, Length=233, Percent_Identity=26.1802575107296, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790861, Length=249, Percent_Identity=25.3012048192771, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788549, Length=215, Percent_Identity=25.1162790697674, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081816, Length=250, Percent_Identity=25.2, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788279, Length=252, Percent_Identity=23.015873015873, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51579; Mature: 51579

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTIRKRLSILFVICSVAGILLVTLFVNATINNKFDAYIVDVQDKRYQRIVSYFEEVYKA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
QGKWTKNSGVELMHEAHMGNYCLTLLDINKKTIWGMNPNDIRLNTMPVKDRGVYNTKTFE
CCCCCCCCCHHHHHHHCCCCEEEEEEECCCCEEECCCCCCEEEEEECCCCCCCCCCEEEE
IKSEGKVVGYVGIGQYSSLLLSEEDISFKTSINKSIVASGILTLVIIITISLYFSKQFSI
EECCCCEEEEEECCCHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PIKEVANLSVNLSKGDFDGKSSVESNIEELENLRKSVNILAEKLKHQDSIRRRLVSDISH
CHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIRTPLNVLQNNLEAMIDGVLPVTEERLNCLNEEVVRFGRLLNNLNVLKEFESESIKLNF
HHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHH
QKIFLDELIADICSDFYAIAENKNIKLQYHIENHEDYSITGDRDRLKQVFINLLSNALKF
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHC
TEDGGEVLIKIYKSDKNIVVEVKDNGVGIKKEDLPFIFERLYRGDKSRHQFKGNGIGLTI
CCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCEEHHH
VKNILQLHYASIDLESEEGEGTTFKVYFHRM
HHHHHHHHHHHEEEECCCCCCCEEEEEEECC
>Mature Secondary Structure
MHTIRKRLSILFVICSVAGILLVTLFVNATINNKFDAYIVDVQDKRYQRIVSYFEEVYKA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
QGKWTKNSGVELMHEAHMGNYCLTLLDINKKTIWGMNPNDIRLNTMPVKDRGVYNTKTFE
CCCCCCCCCHHHHHHHCCCCEEEEEEECCCCEEECCCCCCEEEEEECCCCCCCCCCEEEE
IKSEGKVVGYVGIGQYSSLLLSEEDISFKTSINKSIVASGILTLVIIITISLYFSKQFSI
EECCCCEEEEEECCCHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PIKEVANLSVNLSKGDFDGKSSVESNIEELENLRKSVNILAEKLKHQDSIRRRLVSDISH
CHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIRTPLNVLQNNLEAMIDGVLPVTEERLNCLNEEVVRFGRLLNNLNVLKEFESESIKLNF
HHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHH
QKIFLDELIADICSDFYAIAENKNIKLQYHIENHEDYSITGDRDRLKQVFINLLSNALKF
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHC
TEDGGEVLIKIYKSDKNIVVEVKDNGVGIKKEDLPFIFERLYRGDKSRHQFKGNGIGLTI
CCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCEEHHH
VKNILQLHYASIDLESEEGEGTTFKVYFHRM
HHHHHHHHHHHEEEECCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]