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The map label for this gene is fecD [C]

Identifier: 148378965

GI number: 148378965

Start: 1071951

End: 1073030

Strand: Reverse

Name: fecD [C]

Synonym: CBO0973

Alternate gene names: 148378965

Gene position: 1073030-1071951 (Counterclockwise)

Preceding gene: 148378966

Following gene: 148378964

Centisome position: 27.61

GC content: 30.56

Gene sequence:

>1080_bases
TTGGTGATAAGAATGAATAATAATAAACAAATTTTAAAGTGCAAAAATAATTGCACTTTAAAATTTATTCTATTAATTAT
AGCCTTGTTTGTAATAACTACGGTTTGCATAACCTTTGGTTCTGTAAAAATAGATGTAGGTGTAACCTTTAAATCCCTTA
TAAATAACATATTAAACAAAGAAATTTTTGCTAAAGATTGGCCAAATAATATTGATAATATAGTTTTTAAATTAAGACTT
CCAAGATTGCTTTTAGCCATAGTTTCTGGTGGTGCTTTAGCCCTTGTGGGAATTTTAATGCAAACTTTAACTAGAAACTC
ATTAGCAGACCCATACATATTAGGCATATCCTCTGGTGCATCTGCAGGGGCTACCCTATCCATAGTATTAGGTGTTTTAA
GTTCTTTTGGACATTTTGGAATAGCCTTGGGAGCATTTTTAGGTGCTATGATTGCATCTATTATGGTATTTAAAATATCC
GGAGTAAGTAAAGTGTATTCTAAAACTAAATTAATACTAACTGGAGTTGCTGTATCCTCTATATTTACTGCAGTAACAAA
TTTTATAATAACATTTGCCAGAAATGATAGCTTAGTTAAAAGTGCAGTATTTTGGACTATTGGTAGTTTAGCAGGAGCAA
ATTATAATCAAGTAAAGTTTTCTCTTGTAATAATGGTTATAACCGCCATTTTAAGCATGTTATTATATAAAGATTTAGAT
GCTATGCTGTTAGGTGAGGCCGTAGCAAAAAATATAGGTATAAATACTAAATTTATAATTAGATTTATAATGATAGCTTC
TACGCTTTTAACAGGTACTATAGTGGCTTTTACAGGCATAATTGGATTTGTAGGCCTCATAGTTCCTCATATAGCAAGGC
AAATGGTAGGCTCTTCTCATAAAAAATTAATACCCTTTGGTATTGTTATTGGATCAATATTAATGGTAATTACAGATACT
ATAGCTAGAACTATATTATCTCCACAGGAAGTTCCTATAGGAGTAATAACTGCATTTTTAGGAGGTCCTTTCTTCCTATA
TTTAATGCAAAAAAGCACCTATAGATTTGGAGGTAAGTAA

Upstream 100 bases:

>100_bases
CAAGTTTATAAAAGTTGAATTAACTGAATTATATCCTGGTGTAAGAGTTCCTAAAACTGTAAATAAATTAGCTAAAGAAT
TCTACCCAGATAAATTTTAG

Downstream 100 bases:

>100_bases
ATGAAATTAAAATTAGAAGGTATAAAATATGATATAGGTTCCAAAAAACTTTTACGTGGAATAGATTTAAATGTAGAGAA
AAACCATTTTGTTGGATTAA

Product: iron chelate uptake ABC transporter, FeCT family, permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MVIRMNNNKQILKCKNNCTLKFILLIIALFVITTVCITFGSVKIDVGVTFKSLINNILNKEIFAKDWPNNIDNIVFKLRL
PRLLLAIVSGGALALVGILMQTLTRNSLADPYILGISSGASAGATLSIVLGVLSSFGHFGIALGAFLGAMIASIMVFKIS
GVSKVYSKTKLILTGVAVSSIFTAVTNFIITFARNDSLVKSAVFWTIGSLAGANYNQVKFSLVIMVITAILSMLLYKDLD
AMLLGEAVAKNIGINTKFIIRFIMIASTLLTGTIVAFTGIIGFVGLIVPHIARQMVGSSHKKLIPFGIVIGSILMVITDT
IARTILSPQEVPIGVITAFLGGPFFLYLMQKSTYRFGGK

Sequences:

>Translated_359_residues
MVIRMNNNKQILKCKNNCTLKFILLIIALFVITTVCITFGSVKIDVGVTFKSLINNILNKEIFAKDWPNNIDNIVFKLRL
PRLLLAIVSGGALALVGILMQTLTRNSLADPYILGISSGASAGATLSIVLGVLSSFGHFGIALGAFLGAMIASIMVFKIS
GVSKVYSKTKLILTGVAVSSIFTAVTNFIITFARNDSLVKSAVFWTIGSLAGANYNQVKFSLVIMVITAILSMLLYKDLD
AMLLGEAVAKNIGINTKFIIRFIMIASTLLTGTIVAFTGIIGFVGLIVPHIARQMVGSSHKKLIPFGIVIGSILMVITDT
IARTILSPQEVPIGVITAFLGGPFFLYLMQKSTYRFGGK
>Mature_359_residues
MVIRMNNNKQILKCKNNCTLKFILLIIALFVITTVCITFGSVKIDVGVTFKSLINNILNKEIFAKDWPNNIDNIVFKLRL
PRLLLAIVSGGALALVGILMQTLTRNSLADPYILGISSGASAGATLSIVLGVLSSFGHFGIALGAFLGAMIASIMVFKIS
GVSKVYSKTKLILTGVAVSSIFTAVTNFIITFARNDSLVKSAVFWTIGSLAGANYNQVKFSLVIMVITAILSMLLYKDLD
AMLLGEAVAKNIGINTKFIIRFIMIASTLLTGTIVAFTGIIGFVGLIVPHIARQMVGSSHKKLIPFGIVIGSILMVITDT
IARTILSPQEVPIGVITAFLGGPFFLYLMQKSTYRFGGK

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=288, Percent_Identity=35.4166666666667, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1788004, Length=301, Percent_Identity=31.5614617940199, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790741, Length=285, Percent_Identity=30.5263157894737, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786805, Length=298, Percent_Identity=35.2348993288591, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786347, Length=283, Percent_Identity=30.0353356890459, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786804, Length=337, Percent_Identity=27.0029673590504, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 38565; Mature: 38565

Theoretical pI: Translated: 10.79; Mature: 10.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIRMNNNKQILKCKNNCTLKFILLIIALFVITTVCITFGSVKIDVGVTFKSLINNILNK
CEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
EIFAKDWPNNIDNIVFKLRLPRLLLAIVSGGALALVGILMQTLTRNSLADPYILGISSGA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCC
SAGATLSIVLGVLSSFGHFGIALGAFLGAMIASIMVFKISGVSKVYSKTKLILTGVAVSS
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IFTAVTNFIITFARNDSLVKSAVFWTIGSLAGANYNQVKFSLVIMVITAILSMLLYKDLD
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AMLLGEAVAKNIGINTKFIIRFIMIASTLLTGTIVAFTGIIGFVGLIVPHIARQMVGSSH
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KKLIPFGIVIGSILMVITDTIARTILSPQEVPIGVITAFLGGPFFLYLMQKSTYRFGGK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVIRMNNNKQILKCKNNCTLKFILLIIALFVITTVCITFGSVKIDVGVTFKSLINNILNK
CEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
EIFAKDWPNNIDNIVFKLRLPRLLLAIVSGGALALVGILMQTLTRNSLADPYILGISSGA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCC
SAGATLSIVLGVLSSFGHFGIALGAFLGAMIASIMVFKISGVSKVYSKTKLILTGVAVSS
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IFTAVTNFIITFARNDSLVKSAVFWTIGSLAGANYNQVKFSLVIMVITAILSMLLYKDLD
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AMLLGEAVAKNIGINTKFIIRFIMIASTLLTGTIVAFTGIIGFVGLIVPHIARQMVGSSH
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KKLIPFGIVIGSILMVITDTIARTILSPQEVPIGVITAFLGGPFFLYLMQKSTYRFGGK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]