Click here to switch to the map view.

The map label for this gene is cotA [H]

Identifier: 148378881

GI number: 148378881

Start: 993825

End: 995624

Strand: Reverse

Name: cotA [H]

Synonym: CBO0890

Alternate gene names: 148378881

Gene position: 995624-993825 (Counterclockwise)

Preceding gene: 148378883

Following gene: 148378876

Centisome position: 25.61

GC content: 41.0

Gene sequence:

>1800_bases
ATGGAAGTAAATCCTCTTGATCCTAAGTTAATACCCAAGTATACGCAAGAATTGGTTATACCTCCATCATTCCTACCTAC
CATATGTACAAGCTCTGTGAGTGGTGCTGTAAGTTATAACTATACAGTTACTATGAATCAGTTTGAACAACAAATTCTTC
CACCAGAATTTAATCCTACTACAGTATGGGGATATGGTGGAACAATCAAGGATACTTCAACTGGAGAGGAAGTTAAATTT
CAAAATGCCCCTGGGCCAACTTTTGAAGCTGTAAGAGATATCCCTATAAATGTTAAATGGGTAAACGAAATTACAGCTCC
ATATTCCTTAGCAGTTGATCCAACTATACACTGGGCTAATCCTAATAATACGCCTATGACGCCACCACCTGGAGGTTGGC
CTCCGTTTCCACCGGGAGTGCCGGAAGATCAGAAGGATGTACCGCTAGTAACTCATCTTCACGGAGGTGAACAAGCCTCC
ATGTTCGACGGTAACCCAGAAGCATGGTGGACAGCAAAAGGTTTAAAGGGTCCAAAGTATATTACAGATACTTTTCATTA
CCCCAATGTCCAAGAGTCTACAACTTTGTGGTATCATGATCATGCATTAGGAGTAACCCGACTTAATGTTGTAATGGGAC
TAGCAGGCTTTTATATTCTCAGAGATCCTGCCAATCCACTTGATTATCCAGGATCACTGATTACAAGCGCAAAATATGAA
GTACCAATAGCTATACAGGATCGTTCCTTCAATGAAGATGGTAGCCTCAACTTCCCTTCAGAGGGAGATAATCCAACAAT
TCATCCTTATTGGCAGCCGGAATTCTTTGGTGACACTATTATGGTAAATGGAAGAGTATGGCCAAATCTCAATGTAGATA
TGACCAAGTATCGTTTTAGATTATTAAATGGTTCAAATGCAAGGTTTTACAACCTCAAGTTTTCCAATGGAATGCAGTTT
TGGCAAATAGGAACTGATGGAGGTTATCTTAATAAGCCTGTACCTCTCACATCACTTCTTATTTCACCAGGCGAACGTGC
AGATATACTTGTGGATTTTACAGAAATACCTGCTGGTACTAAAATCATTCTAAATAACGATGCAAATGCACCATATCCTA
CTGGAGATGCGCCTGATAAGGATACTACAGGTCAGATTATGCAGTTTACTGTTCAAGATAACATGACAATGCCACCTGAA
CTTCCTGAAAAGTTGAGATGTGAGCCTGTGCCCAAACTTCAGTCACCATGCAAGAAAAGAGTATTGACTTTGTATGAAAT
CGCAGGGCCTAATGGACCACAAATGGTGACATTAAATGGTCAAACATGGTCCGCTCCTGTTTCGGAATTACCTGTTGTAG
GTTCAACAGAAGAATGGGATATTGTCAACCTTACTATGGATGCACATCCAATTCATTTACATCTGGTACAGTTCAAGATA
GCTTGTAGACAAGCCTTTGATGTAAATGCATATACCGAGGACTGGCTTGATTTGAATTCTGATATAGGATTACCTCCATG
GATGACCACACCAAAGGCTCTTTGTCCAGGATCATATACTATAGGGGATAATCAGCCACCTGCAGCTAATGAAGCAGGCT
GGAAGGATACGATACAAGCCCCCCCTGGAGAGATATCAAGAATCCGAGTTCGTTTTGCACCGCAAAATGTTGAGTGCTCC
TGTCCTGGAGAAAACTTGTATCCATTTGATCCATCCAAGGGTCCAGATTATGTATGGCATTGCCATATATTGGACCATGA
AGATAATGATATGATGAGGCCATATCGAGTTTTGCCATAA

Upstream 100 bases:

>100_bases
TACAGGTATTAATAATGAATGAAGTAGCAAAATAAGCCCTTTAGGCATATTATAAATTAGGTTTATTAAACCAAGTTTGT
AAATAAGGAGTTGTGTAGTT

Downstream 100 bases:

>100_bases
TTTATATATTAAGGTACCATACTCCAAATTATGGTACCTTAATATATCAAATCTTGATAGGGGCAATAATAACCTCCTTG
CATCAGGGGTAAAGTAAATG

Product: spore coat protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MEVNPLDPKLIPKYTQELVIPPSFLPTICTSSVSGAVSYNYTVTMNQFEQQILPPEFNPTTVWGYGGTIKDTSTGEEVKF
QNAPGPTFEAVRDIPINVKWVNEITAPYSLAVDPTIHWANPNNTPMTPPPGGWPPFPPGVPEDQKDVPLVTHLHGGEQAS
MFDGNPEAWWTAKGLKGPKYITDTFHYPNVQESTTLWYHDHALGVTRLNVVMGLAGFYILRDPANPLDYPGSLITSAKYE
VPIAIQDRSFNEDGSLNFPSEGDNPTIHPYWQPEFFGDTIMVNGRVWPNLNVDMTKYRFRLLNGSNARFYNLKFSNGMQF
WQIGTDGGYLNKPVPLTSLLISPGERADILVDFTEIPAGTKIILNNDANAPYPTGDAPDKDTTGQIMQFTVQDNMTMPPE
LPEKLRCEPVPKLQSPCKKRVLTLYEIAGPNGPQMVTLNGQTWSAPVSELPVVGSTEEWDIVNLTMDAHPIHLHLVQFKI
ACRQAFDVNAYTEDWLDLNSDIGLPPWMTTPKALCPGSYTIGDNQPPAANEAGWKDTIQAPPGEISRIRVRFAPQNVECS
CPGENLYPFDPSKGPDYVWHCHILDHEDNDMMRPYRVLP

Sequences:

>Translated_599_residues
MEVNPLDPKLIPKYTQELVIPPSFLPTICTSSVSGAVSYNYTVTMNQFEQQILPPEFNPTTVWGYGGTIKDTSTGEEVKF
QNAPGPTFEAVRDIPINVKWVNEITAPYSLAVDPTIHWANPNNTPMTPPPGGWPPFPPGVPEDQKDVPLVTHLHGGEQAS
MFDGNPEAWWTAKGLKGPKYITDTFHYPNVQESTTLWYHDHALGVTRLNVVMGLAGFYILRDPANPLDYPGSLITSAKYE
VPIAIQDRSFNEDGSLNFPSEGDNPTIHPYWQPEFFGDTIMVNGRVWPNLNVDMTKYRFRLLNGSNARFYNLKFSNGMQF
WQIGTDGGYLNKPVPLTSLLISPGERADILVDFTEIPAGTKIILNNDANAPYPTGDAPDKDTTGQIMQFTVQDNMTMPPE
LPEKLRCEPVPKLQSPCKKRVLTLYEIAGPNGPQMVTLNGQTWSAPVSELPVVGSTEEWDIVNLTMDAHPIHLHLVQFKI
ACRQAFDVNAYTEDWLDLNSDIGLPPWMTTPKALCPGSYTIGDNQPPAANEAGWKDTIQAPPGEISRIRVRFAPQNVECS
CPGENLYPFDPSKGPDYVWHCHILDHEDNDMMRPYRVLP
>Mature_599_residues
MEVNPLDPKLIPKYTQELVIPPSFLPTICTSSVSGAVSYNYTVTMNQFEQQILPPEFNPTTVWGYGGTIKDTSTGEEVKF
QNAPGPTFEAVRDIPINVKWVNEITAPYSLAVDPTIHWANPNNTPMTPPPGGWPPFPPGVPEDQKDVPLVTHLHGGEQAS
MFDGNPEAWWTAKGLKGPKYITDTFHYPNVQESTTLWYHDHALGVTRLNVVMGLAGFYILRDPANPLDYPGSLITSAKYE
VPIAIQDRSFNEDGSLNFPSEGDNPTIHPYWQPEFFGDTIMVNGRVWPNLNVDMTKYRFRLLNGSNARFYNLKFSNGMQF
WQIGTDGGYLNKPVPLTSLLISPGERADILVDFTEIPAGTKIILNNDANAPYPTGDAPDKDTTGQIMQFTVQDNMTMPPE
LPEKLRCEPVPKLQSPCKKRVLTLYEIAGPNGPQMVTLNGQTWSAPVSELPVVGSTEEWDIVNLTMDAHPIHLHLVQFKI
ACRQAFDVNAYTEDWLDLNSDIGLPPWMTTPKALCPGSYTIGDNQPPAANEAGWKDTIQAPPGEISRIRVRFAPQNVECS
CPGENLYPFDPSKGPDYVWHCHILDHEDNDMMRPYRVLP

Specific function: Involved in brown pigmentation during sporogenesis [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.antibioticus phenoxazinone synthase (phsA) [H]

Homologues:

Organism=Escherichia coli, GI1786314, Length=496, Percent_Identity=26.008064516129, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1789394, Length=170, Percent_Identity=34.7058823529412, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001117
- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR008972 [H]

Pfam domain/function: PF00394 Cu-oxidase; PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 66791; Mature: 66791

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVNPLDPKLIPKYTQELVIPPSFLPTICTSSVSGAVSYNYTVTMNQFEQQILPPEFNPT
CCCCCCCCCCCCHHHHHEECCCHHHHHHHHCCCCCEEEEEEEEEHHHHHHHCCCCCCCCC
TVWGYGGTIKDTSTGEEVKFQNAPGPTFEAVRDIPINVKWVNEITAPYSLAVDPTIHWAN
EEEECCCEECCCCCCCEEEEECCCCCHHHHHHCCCCEEEECCCCCCCEEEEECCEEEECC
PNNTPMTPPPGGWPPFPPGVPEDQKDVPLVTHLHGGEQASMFDGNPEAWWTAKGLKGPKY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEECCCCCCCEEEECCCCCCCE
ITDTFHYPNVQESTTLWYHDHALGVTRLNVVMGLAGFYILRDPANPLDYPGSLITSAKYE
EEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCEEEEECCCCCCCCCCCCEECCCEE
VPIAIQDRSFNEDGSLNFPSEGDNPTIHPYWQPEFFGDTIMVNGRVWPNLNVDMTKYRFR
EEEEEECCCCCCCCCEECCCCCCCCEECCCCCCCCCCCEEEECCEECCCCCCEEEEEEEE
LLNGSNARFYNLKFSNGMQFWQIGTDGGYLNKPVPLTSLLISPGERADILVDFTEIPAGT
EEECCCCEEEEEEECCCCEEEEEECCCCCCCCCCCHHHEEECCCCCCEEEEEEECCCCCC
KIILNNDANAPYPTGDAPDKDTTGQIMQFTVQDNMTMPPELPEKLRCEPVPKLQSPCKKR
EEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHCCCCCCCHHHHHHHHH
VLTLYEIAGPNGPQMVTLNGQTWSAPVSELPVVGSTEEWDIVNLTMDAHPIHLHLVQFKI
CEEEEEECCCCCCEEEEECCCCCCCCHHHCCCCCCCCCCEEEEEEECCCCEEEEEEEEEE
ACRQAFDVNAYTEDWLDLNSDIGLPPWMTTPKALCPGSYTIGDNQPPAANEAGWKDTIQA
EHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCHHHCCCCEECCCCCCCCCCCCCCCCCCCC
PPGEISRIRVRFAPQNVECSCPGENLYPFDPSKGPDYVWHCHILDHEDNDMMRPYRVLP
CCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCEECCC
>Mature Secondary Structure
MEVNPLDPKLIPKYTQELVIPPSFLPTICTSSVSGAVSYNYTVTMNQFEQQILPPEFNPT
CCCCCCCCCCCCHHHHHEECCCHHHHHHHHCCCCCEEEEEEEEEHHHHHHHCCCCCCCCC
TVWGYGGTIKDTSTGEEVKFQNAPGPTFEAVRDIPINVKWVNEITAPYSLAVDPTIHWAN
EEEECCCEECCCCCCCEEEEECCCCCHHHHHHCCCCEEEECCCCCCCEEEEECCEEEECC
PNNTPMTPPPGGWPPFPPGVPEDQKDVPLVTHLHGGEQASMFDGNPEAWWTAKGLKGPKY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEECCCCCCCEEEECCCCCCCE
ITDTFHYPNVQESTTLWYHDHALGVTRLNVVMGLAGFYILRDPANPLDYPGSLITSAKYE
EEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCEEEEECCCCCCCCCCCCEECCCEE
VPIAIQDRSFNEDGSLNFPSEGDNPTIHPYWQPEFFGDTIMVNGRVWPNLNVDMTKYRFR
EEEEEECCCCCCCCCEECCCCCCCCEECCCCCCCCCCCEEEECCEECCCCCCEEEEEEEE
LLNGSNARFYNLKFSNGMQFWQIGTDGGYLNKPVPLTSLLISPGERADILVDFTEIPAGT
EEECCCCEEEEEEECCCCEEEEEECCCCCCCCCCCHHHEEECCCCCCEEEEEEECCCCCC
KIILNNDANAPYPTGDAPDKDTTGQIMQFTVQDNMTMPPELPEKLRCEPVPKLQSPCKKR
EEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHCCCCCCCHHHHHHHHH
VLTLYEIAGPNGPQMVTLNGQTWSAPVSELPVVGSTEEWDIVNLTMDAHPIHLHLVQFKI
CEEEEEECCCCCCEEEEECCCCCCCCHHHCCCCCCCCCCEEEEEEECCCCEEEEEEEEEE
ACRQAFDVNAYTEDWLDLNSDIGLPPWMTTPKALCPGSYTIGDNQPPAANEAGWKDTIQA
EHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCHHHCCCCEECCCCCCCCCCCCCCCCCCCC
PPGEISRIRVRFAPQNVECSCPGENLYPFDPSKGPDYVWHCHILDHEDNDMMRPYRVLP
CCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969499; 9455482; 9384377; 2821284; 3135411 [H]