Click here to switch to the map view.

The map label for this gene is bmrR [H]

Identifier: 148378847

GI number: 148378847

Start: 961821

End: 962648

Strand: Reverse

Name: bmrR [H]

Synonym: CBO0855

Alternate gene names: 148378847

Gene position: 962648-961821 (Counterclockwise)

Preceding gene: 148378852

Following gene: 148378846

Centisome position: 24.77

GC content: 31.16

Gene sequence:

>828_bases
ATGCAGGGATTATTACGGATTGGACAAGTAAGTAAATTGTATGGAATATCACTTGATACTTTACGTCACTACGACCGGAA
AGGATTATTAAAGCCAATTATTGATCCTCAAAATGATTATCGTTACTACTCCTTAGAACATCTAGATATCCTAGAAATGA
TTTTAGTTGGGAAATACATAAAAATTCCCCTAGATCAAATGAAAGAAAGAATAGATTCGGAAAGTATCGATGGATATTTA
TCAATGGTAAAAGAACAAAAGGAACGTATAAACGAAGAAAAAAAGTTATTAAATCAACTTGATCAATATGCTGAGGATAT
ACTAGAGTTACTTACGACTATTTCTAAGTTTAAAAATGATTACACATTTTCTACTGCTTCAGTTTATAAAGAAATTGATA
TTACCATCTATAGAATAGATTTAGAAACATTACTGCAGGAAGATACCAAATCACAGCAAACAGAAGGGATAGAATCTTTG
GAGCAGTGGGCTTTCTATCATAGCGAGCCGAATGGAACAATAGTAGAGAATGACGAGGTAATTGGTTTTTCATTTGCTGA
CAGTACAATAAATACAACTATACTTCAAAAGCAATTTATATTTGCAGCTGAACATAACATTGTAGCACAGCATCATGTAA
CAGGATATTATTCCAATATTATGTTCTGGGGTGTAAAAAAGGATTTAATGGAATATCTATATAAATTATGTTGTCATTTT
AACTTACACGATTCTGCCCTATTAGTAAAATACAACTTTGCGCTACTTCATAAAAGTATGGAACATGAATATTTTGTAGA
AATATACTTTCCCCAAAATCCAGTTTGA

Upstream 100 bases:

>100_bases
CCCTTTACAAATTAGATTTTTTCAGGTACTATACTTAAAATAAACCCTTGAATTGCTCAAGAGTCAATGGGTGTTGTTAA
ATTTTTTTAAGGAGGATAAA

Downstream 100 bases:

>100_bases
AGACCAATACATTCTATTTGAATAATCAATATCAAAATAATCATGCCAATAAAATGGCGAAAATCATAACGACAACTCTG
AGTGTTCTAGTAATACTAAC

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MQGLLRIGQVSKLYGISLDTLRHYDRKGLLKPIIDPQNDYRYYSLEHLDILEMILVGKYIKIPLDQMKERIDSESIDGYL
SMVKEQKERINEEKKLLNQLDQYAEDILELLTTISKFKNDYTFSTASVYKEIDITIYRIDLETLLQEDTKSQQTEGIESL
EQWAFYHSEPNGTIVENDEVIGFSFADSTINTTILQKQFIFAAEHNIVAQHHVTGYYSNIMFWGVKKDLMEYLYKLCCHF
NLHDSALLVKYNFALLHKSMEHEYFVEIYFPQNPV

Sequences:

>Translated_275_residues
MQGLLRIGQVSKLYGISLDTLRHYDRKGLLKPIIDPQNDYRYYSLEHLDILEMILVGKYIKIPLDQMKERIDSESIDGYL
SMVKEQKERINEEKKLLNQLDQYAEDILELLTTISKFKNDYTFSTASVYKEIDITIYRIDLETLLQEDTKSQQTEGIESL
EQWAFYHSEPNGTIVENDEVIGFSFADSTINTTILQKQFIFAAEHNIVAQHHVTGYYSNIMFWGVKKDLMEYLYKLCCHF
NLHDSALLVKYNFALLHKSMEHEYFVEIYFPQNPV
>Mature_275_residues
MQGLLRIGQVSKLYGISLDTLRHYDRKGLLKPIIDPQNDYRYYSLEHLDILEMILVGKYIKIPLDQMKERIDSESIDGYL
SMVKEQKERINEEKKLLNQLDQYAEDILELLTTISKFKNDYTFSTASVYKEIDITIYRIDLETLLQEDTKSQQTEGIESL
EQWAFYHSEPNGTIVENDEVIGFSFADSTINTTILQKQFIFAAEHNIVAQHHVTGYYSNIMFWGVKKDLMEYLYKLCCHF
NLHDSALLVKYNFALLHKSMEHEYFVEIYFPQNPV

Specific function: Activates transcription of the bmr gene in response to structurally dissimilar drugs. Binds rhodamine as an inducer [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010499
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011256 [H]

Pfam domain/function: PF06445 AraC_E_bind; PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 32370; Mature: 32370

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGLLRIGQVSKLYGISLDTLRHYDRKGLLKPIIDPQNDYRYYSLEHLDILEMILVGKYI
CCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCHHH
KIPLDQMKERIDSESIDGYLSMVKEQKERINEEKKLLNQLDQYAEDILELLTTISKFKND
CCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YTFSTASVYKEIDITIYRIDLETLLQEDTKSQQTEGIESLEQWAFYHSEPNGTIVENDEV
CCCHHHHHHHEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCE
IGFSFADSTINTTILQKQFIFAAEHNIVAQHHVTGYYSNIMFWGVKKDLMEYLYKLCCHF
EEEEECCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHEEECHHHHHHHHHHHHHHCC
NLHDSALLVKYNFALLHKSMEHEYFVEIYFPQNPV
CCCCCEEEEEEHHHHHHHHCCCEEEEEEEECCCCC
>Mature Secondary Structure
MQGLLRIGQVSKLYGISLDTLRHYDRKGLLKPIIDPQNDYRYYSLEHLDILEMILVGKYI
CCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCHHH
KIPLDQMKERIDSESIDGYLSMVKEQKERINEEKKLLNQLDQYAEDILELLTTISKFKND
CCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YTFSTASVYKEIDITIYRIDLETLLQEDTKSQQTEGIESLEQWAFYHSEPNGTIVENDEV
CCCHHHHHHHEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCE
IGFSFADSTINTTILQKQFIFAAEHNIVAQHHVTGYYSNIMFWGVKKDLMEYLYKLCCHF
EEEEECCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHEEECHHHHHHHHHHHHHHCC
NLHDSALLVKYNFALLHKSMEHEYFVEIYFPQNPV
CCCCCEEEEEEHHHHHHHHCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7961792; 8969508; 9384377; 10568751; 10025401; 11201751 [H]