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The map label for this gene is ybiR [C]

Identifier: 148378500

GI number: 148378500

Start: 586914

End: 588203

Strand: Reverse

Name: ybiR [C]

Synonym: CBO0497

Alternate gene names: 148378500

Gene position: 588203-586914 (Counterclockwise)

Preceding gene: 148378501

Following gene: 148378499

Centisome position: 15.13

GC content: 30.39

Gene sequence:

>1290_bases
ATGATTAAAATATTTAATAATTTTAACATGATGCTTCCAGCAATTATATTTATAATAGTTTATGCATTAATTATTTCAGA
AAAAGTAAACAGGGTTGTTGCTTCGCTAGGCGGAGCTGCTATTATGCTTATATTAAAATTAATCACCCAAGAAAAGGCTT
TCTTAAAAATTGATTTTAATACTATAGGCCTATTAGTTGGAATGATGATTATAGTAAATATAACTAAAAGAACAGGTGTC
TTTGAATATATAGCTATAAAAGCAGCTAAATTTTCCAAAGGGAATCCTATTAAAATATTAATACTATTTTCTGTAATAAC
TGCTGTTTTATCTGGAGTATTAGACAACGTTACTACCGTGCTTTTAATAGTACCTGTAACCTTAGTTATAACTAAAACAT
TAGAAATAGATCCGATTCCTTTTTTAATGTGTGAAATATTTGCATCTAACATAGGAGGCACTGCTACTTTAATAGGAGAT
CCACCAAACTTAATGATAGGAAGTGCTGCTGGATTAAGCTTTTTAGATTTTGTTAAGAACTTAGCTCCTGTAATAATAAT
AATACTCACAGTTACATTATTAGGAATAAGACAATTATATAAAAATTCTATGAAAACTTCTGAAGAAGATAAGAAAAAAA
TTATGGCTTTAGATGAAAGTAAAGCTATTCGTGATATGTCTCTTATGAAAAAATGCTTAACAGTACTATTTTTAACTTTA
ATAGGATTCTTAACTCATAGTTATTTAGGTTTTGAATCTGCAACTATCGCCATAGCTGGTTCTGCTATATTATTAGCTAT
AAGCAAAGTAGAGCCAGATGAAATACTACAAGAAACAGAATGGGGTACTATATTCTTTTTCATAGGTTTATTTATAATGA
CTGGAGTTTTAGAAGATGTTGGCATCATGGAAGTCTTAGCACAGAAAACAATGTCACTAACAAAAGGCAACCTAGTTATG
ACGGGAATATTTGTGCTTTGGATATCTGCTATTGCCTCTGCATTTATAGATAATATTCCTTTTGTAGCTACTATGATACC
TTTAATAAAAGCTATGGGCACCATGGGTGGTATGGATATAGTTCCACTTTGGTGGGCATTATCTTTAGGTGCTTGTCTTG
GTGGAAATGGAACTATGATCGGAGCTTCTGCCAACCTAGTAGTAATTGGCATAGCAGAAAAAAGTGGTTATAAAATTTCT
TTTAAAGACTACTTTAAACTTGGGTTTCCTGTAATGTTAGTATCAATAATAATATGTACCGCTTACCTTTTAATGTTTTT
TTTGAAATAA

Upstream 100 bases:

>100_bases
AGAAATCTTTGTTAAATATATAATTAATTGAAAAGGGGTTTATTTATTTCCAAATTCGTATTAAAATCTAGAGGTACGTA
CTAAAATTTTTTATAGGGGG

Downstream 100 bases:

>100_bases
TTTTGAGATGATTTCAAAATTATTTTATAATATTTTGAAAATTGTGGATATTGATACTCGCTTAATGATATAATATAAAC
AAAAGATAACTCACTTAATT

Product: arsenical pump family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MIKIFNNFNMMLPAIIFIIVYALIISEKVNRVVASLGGAAIMLILKLITQEKAFLKIDFNTIGLLVGMMIIVNITKRTGV
FEYIAIKAAKFSKGNPIKILILFSVITAVLSGVLDNVTTVLLIVPVTLVITKTLEIDPIPFLMCEIFASNIGGTATLIGD
PPNLMIGSAAGLSFLDFVKNLAPVIIIILTVTLLGIRQLYKNSMKTSEEDKKKIMALDESKAIRDMSLMKKCLTVLFLTL
IGFLTHSYLGFESATIAIAGSAILLAISKVEPDEILQETEWGTIFFFIGLFIMTGVLEDVGIMEVLAQKTMSLTKGNLVM
TGIFVLWISAIASAFIDNIPFVATMIPLIKAMGTMGGMDIVPLWWALSLGACLGGNGTMIGASANLVVIGIAEKSGYKIS
FKDYFKLGFPVMLVSIIICTAYLLMFFLK

Sequences:

>Translated_429_residues
MIKIFNNFNMMLPAIIFIIVYALIISEKVNRVVASLGGAAIMLILKLITQEKAFLKIDFNTIGLLVGMMIIVNITKRTGV
FEYIAIKAAKFSKGNPIKILILFSVITAVLSGVLDNVTTVLLIVPVTLVITKTLEIDPIPFLMCEIFASNIGGTATLIGD
PPNLMIGSAAGLSFLDFVKNLAPVIIIILTVTLLGIRQLYKNSMKTSEEDKKKIMALDESKAIRDMSLMKKCLTVLFLTL
IGFLTHSYLGFESATIAIAGSAILLAISKVEPDEILQETEWGTIFFFIGLFIMTGVLEDVGIMEVLAQKTMSLTKGNLVM
TGIFVLWISAIASAFIDNIPFVATMIPLIKAMGTMGGMDIVPLWWALSLGACLGGNGTMIGASANLVVIGIAEKSGYKIS
FKDYFKLGFPVMLVSIIICTAYLLMFFLK
>Mature_429_residues
MIKIFNNFNMMLPAIIFIIVYALIISEKVNRVVASLGGAAIMLILKLITQEKAFLKIDFNTIGLLVGMMIIVNITKRTGV
FEYIAIKAAKFSKGNPIKILILFSVITAVLSGVLDNVTTVLLIVPVTLVITKTLEIDPIPFLMCEIFASNIGGTATLIGD
PPNLMIGSAAGLSFLDFVKNLAPVIIIILTVTLLGIRQLYKNSMKTSEEDKKKIMALDESKAIRDMSLMKKCLTVLFLTL
IGFLTHSYLGFESATIAIAGSAILLAISKVEPDEILQETEWGTIFFFIGLFIMTGVLEDVGIMEVLAQKTMSLTKGNLVM
TGIFVLWISAIASAFIDNIPFVATMIPLIKAMGTMGGMDIVPLWWALSLGACLGGNGTMIGASANLVVIGIAEKSGYKIS
FKDYFKLGFPVMLVSIIICTAYLLMFFLK

Specific function: Unknown

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

Organism=Homo sapiens, GI157266326, Length=490, Percent_Identity=35.7142857142857, Blast_Score=251, Evalue=1e-66,
Organism=Escherichia coli, GI1787039, Length=363, Percent_Identity=23.1404958677686, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082277, Length=386, Percent_Identity=21.7616580310881, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28574683, Length=503, Percent_Identity=32.8031809145129, Blast_Score=248, Evalue=7e-66,
Organism=Drosophila melanogaster, GI28574681, Length=503, Percent_Identity=32.8031809145129, Blast_Score=248, Evalue=7e-66,
Organism=Drosophila melanogaster, GI28574685, Length=503, Percent_Identity=32.8031809145129, Blast_Score=248, Evalue=7e-66,
Organism=Drosophila melanogaster, GI28574678, Length=503, Percent_Identity=32.8031809145129, Blast_Score=248, Evalue=7e-66,
Organism=Drosophila melanogaster, GI24581759, Length=503, Percent_Identity=32.8031809145129, Blast_Score=248, Evalue=8e-66,
Organism=Drosophila melanogaster, GI19920704, Length=503, Percent_Identity=32.8031809145129, Blast_Score=247, Evalue=9e-66,
Organism=Drosophila melanogaster, GI45550608, Length=476, Percent_Identity=34.2436974789916, Blast_Score=205, Evalue=4e-53,
Organism=Drosophila melanogaster, GI221472711, Length=497, Percent_Identity=27.5653923541247, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI85724998, Length=468, Percent_Identity=25.4273504273504, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI62484377, Length=468, Percent_Identity=25.4273504273504, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24656008, Length=483, Percent_Identity=26.7080745341615, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24581764, Length=159, Percent_Identity=40.8805031446541, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 46585; Mature: 46585

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIFNNFNMMLPAIIFIIVYALIISEKVNRVVASLGGAAIMLILKLITQEKAFLKIDFN
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEECHH
TIGLLVGMMIIVNITKRTGVFEYIAIKAAKFSKGNPIKILILFSVITAVLSGVLDNVTTV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
LLIVPVTLVITKTLEIDPIPFLMCEIFASNIGGTATLIGDPPNLMIGSAAGLSFLDFVKN
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEECCCCHHHHHHHHH
LAPVIIIILTVTLLGIRQLYKNSMKTSEEDKKKIMALDESKAIRDMSLMKKCLTVLFLTL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IGFLTHSYLGFESATIAIAGSAILLAISKVEPDEILQETEWGTIFFFIGLFIMTGVLEDV
HHHHHHHHCCCCCCEEEEECHHHEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GIMEVLAQKTMSLTKGNLVMTGIFVLWISAIASAFIDNIPFVATMIPLIKAMGTMGGMDI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHH
VPLWWALSLGACLGGNGTMIGASANLVVIGIAEKSGYKISFKDYFKLGFPVMLVSIIICT
HHHHHHHHHHHHCCCCCCEEECCCCEEEEEEECCCCCEEEHHHHHHCCHHHHHHHHHHHH
AYLLMFFLK
HHHHHHHCC
>Mature Secondary Structure
MIKIFNNFNMMLPAIIFIIVYALIISEKVNRVVASLGGAAIMLILKLITQEKAFLKIDFN
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEECHH
TIGLLVGMMIIVNITKRTGVFEYIAIKAAKFSKGNPIKILILFSVITAVLSGVLDNVTTV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
LLIVPVTLVITKTLEIDPIPFLMCEIFASNIGGTATLIGDPPNLMIGSAAGLSFLDFVKN
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEECCCCHHHHHHHHH
LAPVIIIILTVTLLGIRQLYKNSMKTSEEDKKKIMALDESKAIRDMSLMKKCLTVLFLTL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IGFLTHSYLGFESATIAIAGSAILLAISKVEPDEILQETEWGTIFFFIGLFIMTGVLEDV
HHHHHHHHCCCCCCEEEEECHHHEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GIMEVLAQKTMSLTKGNLVMTGIFVLWISAIASAFIDNIPFVATMIPLIKAMGTMGGMDI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHH
VPLWWALSLGACLGGNGTMIGASANLVVIGIAEKSGYKISFKDYFKLGFPVMLVSIIICT
HHHHHHHHHHHHCCCCCCEEECCCCEEEEEEECCCCCEEEHHHHHHCCHHHHHHHHHHHH
AYLLMFFLK
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]