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The map label for this gene is aroQ

Identifier: 148360919

GI number: 148360919

Start: 558057

End: 558494

Strand: Reverse

Name: aroQ

Synonym: LPC_2879

Alternate gene names: 148360919

Gene position: 558494-558057 (Counterclockwise)

Preceding gene: 148360916

Following gene: 148360920

Centisome position: 15.62

GC content: 38.81

Gene sequence:

>438_bases
ATGAAAAAAATTCTAGTATTACATGGTCCTAATCTAAACCTTTTAGGCTCCCGAGAACCGTCCATTTATGGACATGCTTC
GTTAACTGAAATCAATGGTGATTTAATCCAGGAAGCAGACAATGCAGGGATTCGACTCAGCTGCTTTCAAAGCAATGCTG
AAGCAGAGTTAATTCAAGCTGTCCATCAGGCTGGAATTGATAAAATCAATTACATTATCATAAATCCTGCAGCATTTACT
CACACAAGCATTGCTCTTAGAGATGCTTTAAGTGCGGTTGCCATCCCATTTATTGAGGTTCATTTAAGTAACATTTTTTC
CCGTGAAACTTTTCGTCACCATTCCTATTTCTCAGATATTGCCGTTGGTGTCATTAGCGGTTTGGGGACGAAAGGGTATT
TACTGGCCTTACAAGCGATTATCAAAGAATTAAAGTAG

Upstream 100 bases:

>100_bases
TGCTAAACTTGCGGAGATCTTGCCGATATCCTCGCAGATATATAGACATGTTCATAAAGTTCAGGCAAAATCTGCAAATC
TCAGACTATACCGATGTGTA

Downstream 100 bases:

>100_bases
AGAGAAAAACAAATGGATATCAGAAAAATCAGAAAACTTATTGAACTCCTGGAAGAAACTGGTATTTCAGAGATTGAAAT
CAAAGAAGGAGAAGAGTCGT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MKKILVLHGPNLNLLGSREPSIYGHASLTEINGDLIQEADNAGIRLSCFQSNAEAELIQAVHQAGIDKINYIIINPAAFT
HTSIALRDALSAVAIPFIEVHLSNIFSRETFRHHSYFSDIAVGVISGLGTKGYLLALQAIIKELK

Sequences:

>Translated_145_residues
MKKILVLHGPNLNLLGSREPSIYGHASLTEINGDLIQEADNAGIRLSCFQSNAEAELIQAVHQAGIDKINYIIINPAAFT
HTSIALRDALSAVAIPFIEVHLSNIFSRETFRHHSYFSDIAVGVISGLGTKGYLLALQAIIKELK
>Mature_145_residues
MKKILVLHGPNLNLLGSREPSIYGHASLTEINGDLIQEADNAGIRLSCFQSNAEAELIQAVHQAGIDKINYIIINPAAFT
HTSIALRDALSAVAIPFIEVHLSNIFSRETFRHHSYFSDIAVGVISGLGTKGYLLALQAIIKELK

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_LEGPA (Q5X7S5)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_122868.1
- HSSP:   P43877
- ProteinModelPortal:   Q5X7S5
- SMR:   Q5X7S5
- STRING:   Q5X7S5
- GeneID:   3117664
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp0530
- LegioList:   lpp0530
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   TFQSNHE
- ProtClustDB:   PRK05395
- BioCyc:   LPNE297246:LPP0530-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15775; Mature: 15775

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 23-23 ACT_SITE 101-101 BINDING 75-75 BINDING 81-81 BINDING 88-88 BINDING 112-112

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILVLHGPNLNLLGSREPSIYGHASLTEINGDLIQEADNAGIRLSCFQSNAEAELIQA
CCEEEEEECCCCCEECCCCCCEECCCEEECCCHHHHHHCCCCCEEEEEECCCCHHHHHHH
VHQAGIDKINYIIINPAAFTHTSIALRDALSAVAIPFIEVHLSNIFSRETFRHHSYFSDI
HHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGVISGLGTKGYLLALQAIIKELK
HHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKILVLHGPNLNLLGSREPSIYGHASLTEINGDLIQEADNAGIRLSCFQSNAEAELIQA
CCEEEEEECCCCCEECCCCCCEECCCEEECCCHHHHHHCCCCCEEEEEECCCCHHHHHHH
VHQAGIDKINYIIINPAAFTHTSIALRDALSAVAIPFIEVHLSNIFSRETFRHHSYFSDI
HHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGVISGLGTKGYLLALQAIIKELK
HHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA