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The map label for this gene is yrbG [H]

Identifier: 148360457

GI number: 148360457

Start: 1078426

End: 1079385

Strand: Reverse

Name: yrbG [H]

Synonym: LPC_2396

Alternate gene names: 148360457

Gene position: 1079385-1078426 (Counterclockwise)

Preceding gene: 148360456

Following gene: 148360464

Centisome position: 30.18

GC content: 36.25

Gene sequence:

>960_bases
ATGAACCCTATTCTGAATTTGATTATCAGTTTTATTGCCCTTCTTTGGGCTGCCAATCATTTGGTTGCTGGTGCCTCAGG
GCTGGCAATTCGTTTTCAATTATCCCCCCTTATGATTGGTTTAACTATTGTTGCATTGGGTACCAGTGCCCCCGAATTAT
TTATCTCAATCATTTCTTCCTTAAAAGATAAAAATGACCTGGCAATTGGAAATGCGATTGGCTCAAATATAGCAAATATT
GGCTTAATTTTAGGGATTATAATCCTTATCAAACCAACCTCTTTTCATTTCAATAAACTAAAAAAAGTATACCCAATATT
GATAATTGTCATGCTGTTTGCGTACAGCTTAATACTTGACGGTTATTTGGGTACAATTGATGGTTGCCTTTTTTTGATCG
GATGTATAGCAGTACTCTGTTATTTCATTTATTTAGCTAGTCACTCGCCTAAAAGAGATTTATCAGTTAATGAATTTAGA
CCCGCGATACTATCCTATCGTTCAACACCCTCTAATTTATTGAGTATCGCAATAGGTTTATTGATTCTGCCTATTTGTTC
AAAATACCTGGTTTATAATGCATCTGAAATTGCAAAATGGGCTGGTATAAGTGAATTCACCATTGGCTTGACCATTATTG
CTATAGGTTCCTCCTTGCCAGAACTTACAACGTCCCTTGTTGCCGCTATCAAAGGAGAAGACTCTATAGCGATAGGTACG
ATAATTGGCTCAAATATTTATAACCTGTTGTTAATCTTAGCTCTACCGGGATTACTAAACCCAACTAAAATTAGCAGCGT
CGTATTATGGCGTGATATGCCAGTGATGCTTTCCATTACCTTACTTTTATTGTTTTTAAATTACTATTATCAAAAAAAGA
CATCCTCCTGGCCTGGGGGGATACTTTTGCTTGTGTATTTTTGTTACATGGCTTCTTTGATTATTAACGCACACAGTTAG

Upstream 100 bases:

>100_bases
TCCTGGCAAAACCTGAATATAAAGTGACACTTAATATCTATAAGTTATATCCTATAAACCATTCTCGTATTATTATCACT
AAAAAATATCGAGTACAAAA

Downstream 100 bases:

>100_bases
CTAAAACTAACCTGGCCTGGTTTACCCAGGTTTTTAAGAAAGCATTTGAATCAAGGAAATTAGCTTAAAGTAAAAAACTT
ATAAACCATTATCAACGGGA

Product: Na/Ca antiporter

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MNPILNLIISFIALLWAANHLVAGASGLAIRFQLSPLMIGLTIVALGTSAPELFISIISSLKDKNDLAIGNAIGSNIANI
GLILGIIILIKPTSFHFNKLKKVYPILIIVMLFAYSLILDGYLGTIDGCLFLIGCIAVLCYFIYLASHSPKRDLSVNEFR
PAILSYRSTPSNLLSIAIGLLILPICSKYLVYNASEIAKWAGISEFTIGLTIIAIGSSLPELTTSLVAAIKGEDSIAIGT
IIGSNIYNLLLILALPGLLNPTKISSVVLWRDMPVMLSITLLLLFLNYYYQKKTSSWPGGILLLVYFCYMASLIINAHS

Sequences:

>Translated_319_residues
MNPILNLIISFIALLWAANHLVAGASGLAIRFQLSPLMIGLTIVALGTSAPELFISIISSLKDKNDLAIGNAIGSNIANI
GLILGIIILIKPTSFHFNKLKKVYPILIIVMLFAYSLILDGYLGTIDGCLFLIGCIAVLCYFIYLASHSPKRDLSVNEFR
PAILSYRSTPSNLLSIAIGLLILPICSKYLVYNASEIAKWAGISEFTIGLTIIAIGSSLPELTTSLVAAIKGEDSIAIGT
IIGSNIYNLLLILALPGLLNPTKISSVVLWRDMPVMLSITLLLLFLNYYYQKKTSSWPGGILLLVYFCYMASLIINAHS
>Mature_319_residues
MNPILNLIISFIALLWAANHLVAGASGLAIRFQLSPLMIGLTIVALGTSAPELFISIISSLKDKNDLAIGNAIGSNIANI
GLILGIIILIKPTSFHFNKLKKVYPILIIVMLFAYSLILDGYLGTIDGCLFLIGCIAVLCYFIYLASHSPKRDLSVNEFR
PAILSYRSTPSNLLSIAIGLLILPICSKYLVYNASEIAKWAGISEFTIGLTIIAIGSSLPELTTSLVAAIKGEDSIAIGT
IIGSNIYNLLLILALPGLLNPTKISSVVLWRDMPVMLSITLLLLFLNYYYQKKTSSWPGGILLLVYFCYMASLIINAHS

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI31563526, Length=136, Percent_Identity=33.0882352941176, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI300796347, Length=137, Percent_Identity=29.9270072992701, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI9966787, Length=137, Percent_Identity=29.9270072992701, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1789587, Length=293, Percent_Identity=38.2252559726962, Blast_Score=173, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 34523; Mature: 34523

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPILNLIISFIALLWAANHLVAGASGLAIRFQLSPLMIGLTIVALGTSAPELFISIISS
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHH
LKDKNDLAIGNAIGSNIANIGLILGIIILIKPTSFHFNKLKKVYPILIIVMLFAYSLILD
HCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GYLGTIDGCLFLIGCIAVLCYFIYLASHSPKRDLSVNEFRPAILSYRSTPSNLLSIAIGL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
LILPICSKYLVYNASEIAKWAGISEFTIGLTIIAIGSSLPELTTSLVAAIKGEDSIAIGT
HHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCEEEHH
IIGSNIYNLLLILALPGLLNPTKISSVVLWRDMPVMLSITLLLLFLNYYYQKKTSSWPGG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCH
ILLLVYFCYMASLIINAHS
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNPILNLIISFIALLWAANHLVAGASGLAIRFQLSPLMIGLTIVALGTSAPELFISIISS
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHH
LKDKNDLAIGNAIGSNIANIGLILGIIILIKPTSFHFNKLKKVYPILIIVMLFAYSLILD
HCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GYLGTIDGCLFLIGCIAVLCYFIYLASHSPKRDLSVNEFRPAILSYRSTPSNLLSIAIGL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
LILPICSKYLVYNASEIAKWAGISEFTIGLTIIAIGSSLPELTTSLVAAIKGEDSIAIGT
HHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCEEEHH
IIGSNIYNLLLILALPGLLNPTKISSVVLWRDMPVMLSITLLLLFLNYYYQKKTSSWPGG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCH
ILLLVYFCYMASLIINAHS
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]