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The map label for this gene is kynB [H]

Identifier: 148360361

GI number: 148360361

Start: 1186571

End: 1187254

Strand: Reverse

Name: kynB [H]

Synonym: LPC_2299

Alternate gene names: 148360361

Gene position: 1187254-1186571 (Counterclockwise)

Preceding gene: 148360360

Following gene: 148360362

Centisome position: 33.2

GC content: 42.84

Gene sequence:

>684_bases
ATGAAATTTCCTTATCACCTCATCGAATTAACCCATACTTTAGATGAAACCAGTCCTTCTTGGGAAGAAAACTGTGGTTT
TTCATCATCACTAATATTGGATTATGCAGATTGTACTAGCGAAGCCTCATTTCGCGTGCAACATCTCACAATGCCAGCAG
GAATGGGAACGCATATGGATGCCCCCTCTCACTGCTGTCCTGATGGGCTATCTATAGACCAAATTCCACTGGATAAATTA
GCCGCTCCTTGTGTGGTGATTGATGTATCTCAAAAGGCACATGAACTTTACAGCGTGACACCTCAAGATATCGCTGACTT
TGAAAAAAAGCATGGCCTTATTCAACCTAATTCATTTGTCATCATCAAAACAGGTTGGTCACGCTTTTGGGACAACCCCT
TCCAATATCGTAACAACCATAATTTTCCCTCTGTCTCGGCAGAAACAGCTACCTTGCTGGTGTCACGGGGCATTGTGGGT
TTAGGCATAGATACCTTATCACCTGACAGGCTAGATGATGGTTATCCTGTGCATCGCATCTTGTTAAATTCAGGACGATA
CATCGTGGAAAACATTGCAAATAGTGAACAATTACCCCCTACAGGTAGTTTTGTCATGGCCTTCCCACTGAAAATCAAAC
AAGCAACCGAGGCACCTATGCGTTTAATTGGATTATTGCCATGA

Upstream 100 bases:

>100_bases
CTAGGAGTCACTTATGACTATAAGTCAGTTGCTCCAGGAAAAATGGTTTCTTTGGATGATGATTTGATATTATGGTTTAC
CAAAAAAGTGAAATAATAAA

Downstream 100 bases:

>100_bases
ATTATCCTCAAGAAAAAATAGAACCCAATCCTGATGCGCAACAAATCAATGAATGTATTAATTTAGTCACTAAAGTTTTA
GGTGACAATCTTTTGGGCGT

Product: hypothetical protein

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKFPYHLIELTHTLDETSPSWEENCGFSSSLILDYADCTSEASFRVQHLTMPAGMGTHMDAPSHCCPDGLSIDQIPLDKL
AAPCVVIDVSQKAHELYSVTPQDIADFEKKHGLIQPNSFVIIKTGWSRFWDNPFQYRNNHNFPSVSAETATLLVSRGIVG
LGIDTLSPDRLDDGYPVHRILLNSGRYIVENIANSEQLPPTGSFVMAFPLKIKQATEAPMRLIGLLP

Sequences:

>Translated_227_residues
MKFPYHLIELTHTLDETSPSWEENCGFSSSLILDYADCTSEASFRVQHLTMPAGMGTHMDAPSHCCPDGLSIDQIPLDKL
AAPCVVIDVSQKAHELYSVTPQDIADFEKKHGLIQPNSFVIIKTGWSRFWDNPFQYRNNHNFPSVSAETATLLVSRGIVG
LGIDTLSPDRLDDGYPVHRILLNSGRYIVENIANSEQLPPTGSFVMAFPLKIKQATEAPMRLIGLLP
>Mature_227_residues
MKFPYHLIELTHTLDETSPSWEENCGFSSSLILDYADCTSEASFRVQHLTMPAGMGTHMDAPSHCCPDGLSIDQIPLDKL
AAPCVVIDVSQKAHELYSVTPQDIADFEKKHGLIQPNSFVIIKTGWSRFWDNPFQYRNNHNFPSVSAETATLLVSRGIVG
LGIDTLSPDRLDDGYPVHRILLNSGRYIVENIANSEQLPPTGSFVMAFPLKIKQATEAPMRLIGLLP

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine [H]

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017484
- InterPro:   IPR007325 [H]

Pfam domain/function: PF04199 Cyclase [H]

EC number: =3.5.1.9 [H]

Molecular weight: Translated: 25182; Mature: 25182

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFPYHLIELTHTLDETSPSWEENCGFSSSLILDYADCTSEASFRVQHLTMPAGMGTHMD
CCCCHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCC
APSHCCPDGLSIDQIPLDKLAAPCVVIDVSQKAHELYSVTPQDIADFEKKHGLIQPNSFV
CCCCCCCCCCCCCCCCHHHHCCCEEEEECCHHHHHHHCCCHHHHHHHHHHCCCCCCCCEE
IIKTGWSRFWDNPFQYRNNHNFPSVSAETATLLVSRGIVGLGIDTLSPDRLDDGYPVHRI
EEECCHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCEEE
LLNSGRYIVENIANSEQLPPTGSFVMAFPLKIKQATEAPMRLIGLLP
EECCCCCEEHHHCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKFPYHLIELTHTLDETSPSWEENCGFSSSLILDYADCTSEASFRVQHLTMPAGMGTHMD
CCCCHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCC
APSHCCPDGLSIDQIPLDKLAAPCVVIDVSQKAHELYSVTPQDIADFEKKHGLIQPNSFV
CCCCCCCCCCCCCCCCHHHHCCCEEEEECCHHHHHHHCCCHHHHHHHHHHCCCCCCCCEE
IIKTGWSRFWDNPFQYRNNHNFPSVSAETATLLVSRGIVGLGIDTLSPDRLDDGYPVHRI
EEECCHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCEEE
LLNSGRYIVENIANSEQLPPTGSFVMAFPLKIKQATEAPMRLIGLLP
EECCCCCEEHHHCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA