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The map label for this gene is cpdP [H]

Identifier: 148359508

GI number: 148359508

Start: 2280556

End: 2281539

Strand: Reverse

Name: cpdP [H]

Synonym: LPC_1418

Alternate gene names: 148359508

Gene position: 2281539-2280556 (Counterclockwise)

Preceding gene: 148359509

Following gene: 148359506

Centisome position: 63.79

GC content: 39.84

Gene sequence:

>984_bases
ATGCGCCAGCTATTCATTATCATGTTTGTTTTTCTATTATCTAATGTAGGATATGGTGCGCCTGCCTTTGAAATTCTTCC
CCTTGGAGTCTATGGTGGTTTGAAAGATGGAAATTTATCAGCTTATTTAATCAAGGCCATCGAGAGCAAAAATTATACGG
CTCTTGATGGGGGCACTTTGGTGCGAGGGCTTGAAGTTGCAGTCGATAAACAGTCACTGTCTAATAAAAGGGTTGACGAT
TTGTTGCAAAAACATATACCAGCCTACCTTATTTCTCATGCCCATCTTGATCATGTTATGGGGCTTGTGATGGCTCAACC
CGAATTGCGAGAAAAGCAAACCATTATGGCACGTGAAGAAACCATGCAGGCATTGCAGAAAAATATTTTTAATTGGTCTG
TTTGGGGGAATTTTGGAGATAGTGGTGACACCCCTCAATTGAATTTTCAACATTACCAAACGGTGCCATTATTCCAGTGG
GTTTCCATTCCTGACACGGATTTGCACGTTAAAGTGTTCCCTCTAAGCCATGGAGGAATGGCATCAAGCGCTTTTTTAAT
CCGTTATGAGGCTGAATACGTCCTCTATTTTGGTGATACTGGTGCTGATAGCATTGAAAAGTCAACCAATATGGAGAACA
TTTGGAAAGAAATTGCCCCACTCATAAGAAATAGGCAGCTGCATGCCATCATGTTGGAGTGCTCATTTTTAAATTCACAG
CCAGACGACAAATTATTTGGTCATCTAAAACCTAACCTATTCATGTCAGAACTGCGACAATTAGCATCGATTGTTGATCC
TTTCGACTCAAGAAACTCACTACGAGGTTTACCCGTTGTTGTTACACACATCAAACCCAGATTAGCTGACTTTTCAAATA
CTAATGAAGATACAGAAAAACAGATTATAAACGAATTGTCCCAGGAAAATGATATTGGCGTCGAATTAATTAAACCTGAG
CAAGGTATAACCTTAAGTTTATGA

Upstream 100 bases:

>100_bases
TATGATGTTGAACTTCCACCGTATAAATACGGTGATTGAAGCAAGGTTGAATAAGGTATTATTTTACAAACTGACCCGAA
TTATTTGAAAGGAAATCCTC

Downstream 100 bases:

>100_bases
TTGATGAAGAGTCACAACAGCTGCCAGAACCAATCCTAATAAATCATTTATGGTATTTGTGTATCAGGGGCTGTTGCGAA
AAATCCGAACCAGAATAAAA

Product: 3',5'-cyclic nucleotide phosphodiesterase

Products: NA

Alternate protein names: 3':5'-CNP; PDEase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MRQLFIIMFVFLLSNVGYGAPAFEILPLGVYGGLKDGNLSAYLIKAIESKNYTALDGGTLVRGLEVAVDKQSLSNKRVDD
LLQKHIPAYLISHAHLDHVMGLVMAQPELREKQTIMAREETMQALQKNIFNWSVWGNFGDSGDTPQLNFQHYQTVPLFQW
VSIPDTDLHVKVFPLSHGGMASSAFLIRYEAEYVLYFGDTGADSIEKSTNMENIWKEIAPLIRNRQLHAIMLECSFLNSQ
PDDKLFGHLKPNLFMSELRQLASIVDPFDSRNSLRGLPVVVTHIKPRLADFSNTNEDTEKQIINELSQENDIGVELIKPE
QGITLSL

Sequences:

>Translated_327_residues
MRQLFIIMFVFLLSNVGYGAPAFEILPLGVYGGLKDGNLSAYLIKAIESKNYTALDGGTLVRGLEVAVDKQSLSNKRVDD
LLQKHIPAYLISHAHLDHVMGLVMAQPELREKQTIMAREETMQALQKNIFNWSVWGNFGDSGDTPQLNFQHYQTVPLFQW
VSIPDTDLHVKVFPLSHGGMASSAFLIRYEAEYVLYFGDTGADSIEKSTNMENIWKEIAPLIRNRQLHAIMLECSFLNSQ
PDDKLFGHLKPNLFMSELRQLASIVDPFDSRNSLRGLPVVVTHIKPRLADFSNTNEDTEKQIINELSQENDIGVELIKPE
QGITLSL
>Mature_327_residues
MRQLFIIMFVFLLSNVGYGAPAFEILPLGVYGGLKDGNLSAYLIKAIESKNYTALDGGTLVRGLEVAVDKQSLSNKRVDD
LLQKHIPAYLISHAHLDHVMGLVMAQPELREKQTIMAREETMQALQKNIFNWSVWGNFGDSGDTPQLNFQHYQTVPLFQW
VSIPDTDLHVKVFPLSHGGMASSAFLIRYEAEYVLYFGDTGADSIEKSTNMENIWKEIAPLIRNRQLHAIMLECSFLNSQ
PDDKLFGHLKPNLFMSELRQLASIVDPFDSRNSLRGLPVVVTHIKPRLADFSNTNEDTEKQIINELSQENDIGVELIKPE
QGITLSL

Specific function: Seems to allow the organism to grow on cAMP [H]

COG id: COG5212

COG function: function code T; Low-affinity cAMP phosphodiesterase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cAMP phosphodiesterase class-II family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321189, Length=250, Percent_Identity=29.6, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR000396 [H]

Pfam domain/function: PF02112 PDEase_II [H]

EC number: =3.1.4.17 [H]

Molecular weight: Translated: 36847; Mature: 36847

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQLFIIMFVFLLSNVGYGAPAFEILPLGVYGGLKDGNLSAYLIKAIESKNYTALDGGTL
CHHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCCCCCCCHHHHHHHHCCCCCEEECCCHH
VRGLEVAVDKQSLSNKRVDDLLQKHIPAYLISHAHLDHVMGLVMAQPELREKQTIMAREE
HHHHHEEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TMQALQKNIFNWSVWGNFGDSGDTPQLNFQHYQTVPLFQWVSIPDTDLHVKVFPLSHGGM
HHHHHHHHCCEEEEECCCCCCCCCCCCCCCEECCCCEEEEECCCCCCEEEEEEEECCCCC
ASSAFLIRYEAEYVLYFGDTGADSIEKSTNMENIWKEIAPLIRNRQLHAIMLECSFLNSQ
CCCEEEEEEEEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCC
PDDKLFGHLKPNLFMSELRQLASIVDPFDSRNSLRGLPVVVTHIKPRLADFSNTNEDTEK
CCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHCCCCCCCHHHH
QIINELSQENDIGVELIKPEQGITLSL
HHHHHHHCCCCCCEEEECCCCCCEECC
>Mature Secondary Structure
MRQLFIIMFVFLLSNVGYGAPAFEILPLGVYGGLKDGNLSAYLIKAIESKNYTALDGGTL
CHHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCCCCCCCHHHHHHHHCCCCCEEECCCHH
VRGLEVAVDKQSLSNKRVDDLLQKHIPAYLISHAHLDHVMGLVMAQPELREKQTIMAREE
HHHHHEEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TMQALQKNIFNWSVWGNFGDSGDTPQLNFQHYQTVPLFQWVSIPDTDLHVKVFPLSHGGM
HHHHHHHHCCEEEEECCCCCCCCCCCCCCCEECCCCEEEEECCCCCCEEEEEEEECCCCC
ASSAFLIRYEAEYVLYFGDTGADSIEKSTNMENIWKEIAPLIRNRQLHAIMLECSFLNSQ
CCCEEEEEEEEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCC
PDDKLFGHLKPNLFMSELRQLASIVDPFDSRNSLRGLPVVVTHIKPRLADFSNTNEDTEK
CCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHCCCCCCCHHHH
QIINELSQENDIGVELIKPEQGITLSL
HHHHHHHCCCCCCEEEECCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8393003 [H]