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The map label for this gene is hipA [C]

Identifier: 148359497

GI number: 148359497

Start: 2266342

End: 2267646

Strand: Reverse

Name: hipA [C]

Synonym: LPC_1407

Alternate gene names: 148359497

Gene position: 2267646-2266342 (Counterclockwise)

Preceding gene: 148359498

Following gene: 148359496

Centisome position: 63.4

GC content: 35.02

Gene sequence:

>1305_bases
ATGAAAATGATTGGAGATAAGTCAGTCTTGGATGTTTATCTCGGTGAAAGTCAAATAGCCAATATCACACTTATCGATGA
TCAACTGTATTGGAGTTATCATGAAAGTTGGCAACAGACAGGGTATGCTATTTCCCCACACCTTCCTATGCATGAAGATA
TTCCACCATTAAATGTGCAACGATTTCTAAGAAATTTATTACCCGAAGGGAATCCTTTAGAAGTACTAGTTAATGTTTTT
CATTTAAGTAAATACAATACATTTGGACTTATTCAAGCTTTAGGGTTGGATACACCTGGGTCATTAGTTATATTGCCATC
AAATCAAGCAATTCCTAAACATGCAAATTTTCGACTAGTAACTCATGAAGAATTAGAAGAGCGTTTAAATCATCGTGATT
CTTACAATTTAATCGTTTGGGACGGAAAACCACGTCTTTCGGTTCCCGGAGTACAAGATAAAATTAATGTGGTGTTAAAT
AAAGAAGGACAACTTGGTTTTGGAGAAGGTAGCTTGTGCTCTACCCATATTCTTAAATTTGAAACACAAAAACTATCTTA
TTTGGTTTTAAATGAATTCCTCAGTATGTGGCTCGCTAAATGCTGTGAATTGAATGTAGCCAATGTTCAGATGAAGCGTT
TTGGTCAGAACCCTGCTTTATTGGTAGAGCGTTTTGATAGAAAATTGATTACCACTACTAATATAGTAAAAAGACGGCAC
TTAATAGATGGTTGTCAGGCAATGAATTTACCCCCTGAATTTAAATATGAGCAAAATTTTGGAAATAGCAGGGATGTGGC
TCATATTAGAGATGGAGTCAGTTTGCCCAAGCTATTTGATTTTGCCAATCAATGTATCAATCCTGCCAAAACCAAGCAGC
AAATACTCGACTGGGTTTTATTTAATGTTTTGATATTTAATTGTGACGCTCACGGTAAAAATATCAGTTTTTTTGTTGGG
GCTAATGGTATTTCACTGGCACCATTTTATGATTTAGTTAATATAAAAATGTATCCTGAATTTGAGCATGCTCTGGCGAT
GGCATTAGGGGATGAATTTGATGGATATAATATTAATGCCTATCAGTTGGCTGATTTTGCAGATACATGTCGGCTGCCAA
GGTCGTTAGTAGCTAAACATTTAAAATATTTGATTGGCAAATTAACAACTGCTTTGCAAGAAGAAACCCAATTTAATTTA
GTTGGTAACGAAGAAGACTATTTTAAGAAATATCAGGAAATTGTCATGAAGAGATGTGAGCACTTGTTAAAGCAGAACGA
CCAAATTACTTCAATAAAGCTCTAG

Upstream 100 bases:

>100_bases
GAGCATGGGCAATCGAACTGTCAATTGGCAAGTGTATTACAAATTTGTTCTGGTTTAGGAATAAGTCTTTACATAAAACC
TTGGATGGATAATAGTGAGG

Downstream 100 bases:

>100_bases
CGCTTTTCCCCACTATTTCTTACTTTAATACGGAGCACATAAGAGATTTGTATATTTAATATACAAACAATCTATTTTAA
TTATAATCAAAATTATCATA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKMIGDKSVLDVYLGESQIANITLIDDQLYWSYHESWQQTGYAISPHLPMHEDIPPLNVQRFLRNLLPEGNPLEVLVNVF
HLSKYNTFGLIQALGLDTPGSLVILPSNQAIPKHANFRLVTHEELEERLNHRDSYNLIVWDGKPRLSVPGVQDKINVVLN
KEGQLGFGEGSLCSTHILKFETQKLSYLVLNEFLSMWLAKCCELNVANVQMKRFGQNPALLVERFDRKLITTTNIVKRRH
LIDGCQAMNLPPEFKYEQNFGNSRDVAHIRDGVSLPKLFDFANQCINPAKTKQQILDWVLFNVLIFNCDAHGKNISFFVG
ANGISLAPFYDLVNIKMYPEFEHALAMALGDEFDGYNINAYQLADFADTCRLPRSLVAKHLKYLIGKLTTALQEETQFNL
VGNEEDYFKKYQEIVMKRCEHLLKQNDQITSIKL

Sequences:

>Translated_434_residues
MKMIGDKSVLDVYLGESQIANITLIDDQLYWSYHESWQQTGYAISPHLPMHEDIPPLNVQRFLRNLLPEGNPLEVLVNVF
HLSKYNTFGLIQALGLDTPGSLVILPSNQAIPKHANFRLVTHEELEERLNHRDSYNLIVWDGKPRLSVPGVQDKINVVLN
KEGQLGFGEGSLCSTHILKFETQKLSYLVLNEFLSMWLAKCCELNVANVQMKRFGQNPALLVERFDRKLITTTNIVKRRH
LIDGCQAMNLPPEFKYEQNFGNSRDVAHIRDGVSLPKLFDFANQCINPAKTKQQILDWVLFNVLIFNCDAHGKNISFFVG
ANGISLAPFYDLVNIKMYPEFEHALAMALGDEFDGYNINAYQLADFADTCRLPRSLVAKHLKYLIGKLTTALQEETQFNL
VGNEEDYFKKYQEIVMKRCEHLLKQNDQITSIKL
>Mature_434_residues
MKMIGDKSVLDVYLGESQIANITLIDDQLYWSYHESWQQTGYAISPHLPMHEDIPPLNVQRFLRNLLPEGNPLEVLVNVF
HLSKYNTFGLIQALGLDTPGSLVILPSNQAIPKHANFRLVTHEELEERLNHRDSYNLIVWDGKPRLSVPGVQDKINVVLN
KEGQLGFGEGSLCSTHILKFETQKLSYLVLNEFLSMWLAKCCELNVANVQMKRFGQNPALLVERFDRKLITTTNIVKRRH
LIDGCQAMNLPPEFKYEQNFGNSRDVAHIRDGVSLPKLFDFANQCINPAKTKQQILDWVLFNVLIFNCDAHGKNISFFVG
ANGISLAPFYDLVNIKMYPEFEHALAMALGDEFDGYNINAYQLADFADTCRLPRSLVAKHLKYLIGKLTTALQEETQFNL
VGNEEDYFKKYQEIVMKRCEHLLKQNDQITSIKL

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4dM [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=324, Percent_Identity=28.7037037037037, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 49661; Mature: 49661

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMIGDKSVLDVYLGESQIANITLIDDQLYWSYHESWQQTGYAISPHLPMHEDIPPLNVQ
CCCCCCCCCEEEEECCCCEEEEEEECCHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCHH
RFLRNLLPEGNPLEVLVNVFHLSKYNTFGLIQALGLDTPGSLVILPSNQAIPKHANFRLV
HHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEE
THEELEERLNHRDSYNLIVWDGKPRLSVPGVQDKINVVLNKEGQLGFGEGSLCSTHILKF
EHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHEEE
ETQKLSYLVLNEFLSMWLAKCCELNVANVQMKRFGQNPALLVERFDRKLITTTNIVKRRH
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHH
LIDGCQAMNLPPEFKYEQNFGNSRDVAHIRDGVSLPKLFDFANQCINPAKTKQQILDWVL
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
FNVLIFNCDAHGKNISFFVGANGISLAPFYDLVNIKMYPEFEHALAMALGDEFDGYNINA
HHHHHEECCCCCCEEEEEEECCCCEECCHHEEEEEEECCCHHHHHHHHHCCCCCCCCCCC
YQLADFADTCRLPRSLVAKHLKYLIGKLTTALQEETQFNLVGNEEDYFKKYQEIVMKRCE
EEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHH
HLLKQNDQITSIKL
HHHHCCCCEEEEEC
>Mature Secondary Structure
MKMIGDKSVLDVYLGESQIANITLIDDQLYWSYHESWQQTGYAISPHLPMHEDIPPLNVQ
CCCCCCCCCEEEEECCCCEEEEEEECCHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCHH
RFLRNLLPEGNPLEVLVNVFHLSKYNTFGLIQALGLDTPGSLVILPSNQAIPKHANFRLV
HHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEE
THEELEERLNHRDSYNLIVWDGKPRLSVPGVQDKINVVLNKEGQLGFGEGSLCSTHILKF
EHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHEEE
ETQKLSYLVLNEFLSMWLAKCCELNVANVQMKRFGQNPALLVERFDRKLITTTNIVKRRH
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHH
LIDGCQAMNLPPEFKYEQNFGNSRDVAHIRDGVSLPKLFDFANQCINPAKTKQQILDWVL
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
FNVLIFNCDAHGKNISFFVGANGISLAPFYDLVNIKMYPEFEHALAMALGDEFDGYNINA
HHHHHEECCCCCCEEEEEEECCCCEECCHHEEEEEEECCCHHHHHHHHHCCCCCCCCCCC
YQLADFADTCRLPRSLVAKHLKYLIGKLTTALQEETQFNLVGNEEDYFKKYQEIVMKRCE
EEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHH
HLLKQNDQITSIKL
HHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]