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The map label for this gene is clpX [H]

Identifier: 148359405

GI number: 148359405

Start: 2163414

End: 2164688

Strand: Reverse

Name: clpX [H]

Synonym: LPC_1305

Alternate gene names: 148359405

Gene position: 2164688-2163414 (Counterclockwise)

Preceding gene: 148359406

Following gene: 148359404

Centisome position: 60.53

GC content: 37.65

Gene sequence:

>1275_bases
ATGAGTAAATCCGGTAACGGAAATGGAGATAAGGTCTTATATTGCTCTTTTTGTGGCAAGAGTCAACATGAGGTAAAAAA
ATTAATTGCTGGACCTTCTGTGTTTGTTTGTGATGAATGTGTAGAGCTATGTAATGATATTATTCGAGAAGAAACACATG
AAACTCATGAAGAAACTGAGGCACGTCTACCGACACCAAAAGAAATATCTAACTTTCTCGATGAATACGTAATAGGGCAA
CAACATGCCAAAAAGGTTTTATCAGTAGCAGTATATAATCACTATAAGAGATTACAGCATAAAAGCGAGGATGGTGTTGA
ACTCGGTAAAAGTAATATACTACTTATAGGACCTACTGGCAGTGGTAAGACTCTTTTAGCTCAAACCCTGGCGCGGATTC
TTAATGTTCCTTTTGCCATGGCTGATGCCACGACCCTTACTGAAGCTGGATATGTTGGTGAAGACGTTGAAAATATCATC
CAGAAGTTATTACAGAAGTGTGACTATGACGTAGATAAGGCGCAGCAAGGTATTGTCTATATCGACGAAATCGATAAGAT
TTCACGCAAATCAGATAATCCATCTATCACCAGAGATGTTTCCGGAGAAGGTGTTCAACAAGCTTTACTGAAATTAATTG
AAGGTACTGTTGCATCTGTTCCACCGCAAGGTGGGCGAAAGCATCCACAGCAGGAATTTTTGCAAGTAGATACATCAAAT
ATTTTATTTATCTGTGGTGGCGCTTTTGCAGGTTTGGACAAAGTAATACGTGAACGCAGCGATAAATCGAGCATAGGTTT
TTCTGCTCAATTAAAAAGCAAAAAAAGCAGTAATGACGAAGTTTCAAAAGTTTTAGGTCAATTGGAATCAGATGATTTAA
TTAAATATGGGTTAATTCCCGAGTTTGTTGGACGTTTGCCTGTTGTAACCACTTTACAGGAACTTGATGAAGCGGCATTG
ATTGATATATTAACGAGACCGAAAAATGCTTTAACAAAGCAATTTCAATCACTTTTCAAAATGGAAGGTTCTGAACTTGA
GTTTAGAGACGAAGCTTTGATTGCTATTGCTAAAAAGGCCCTCGAAAGAAAAATGGGCGCAAGAGGTTTGCGATCAATAC
TTGAAAATATTCTTTTAGACACCATGTATGACTTACCTTCCTTGGAAGGTGTGAATAAGGTTGTTATTGATGAGAGTGTA
GTGAATGGACTATCTAAACCGATTCTCATTTATGAACAGGATGAGAAAAAAAGTGCGTCTGGTAGTAAAGATTAA

Upstream 100 bases:

>100_bases
TTGGTTTGATAGTAATGTGGTGGCGCAATATTATCTGATTGTCTAAAATTTTACATGTAATTACTATTAATTAGTAATAG
CTGTAAGAAGGGGTTTGGTT

Downstream 100 bases:

>100_bases
GTAAGATGTTGATTTCTGCAATAATTTAAATTGTTGCAGAAATCATTTTATCTTTCATTCACAAAATATATTTAAAGCTG
ATTTTGTAGCTTAAAATAAC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETEARLPTPKEISNFLDEYVIGQ
QHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVENII
QKLLQKCDYDVDKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSN
ILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIPEFVGRLPVVTTLQELDEAAL
IDILTRPKNALTKQFQSLFKMEGSELEFRDEALIAIAKKALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDESV
VNGLSKPILIYEQDEKKSASGSKD

Sequences:

>Translated_424_residues
MSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETEARLPTPKEISNFLDEYVIGQ
QHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVENII
QKLLQKCDYDVDKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSN
ILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIPEFVGRLPVVTTLQELDEAAL
IDILTRPKNALTKQFQSLFKMEGSELEFRDEALIAIAKKALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDESV
VNGLSKPILIYEQDEKKSASGSKD
>Mature_423_residues
SKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETEARLPTPKEISNFLDEYVIGQQ
HAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVENIIQ
KLLQKCDYDVDKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSNI
LFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIPEFVGRLPVVTTLQELDEAALI
DILTRPKNALTKQFQSLFKMEGSELEFRDEALIAIAKKALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDESVV
NGLSKPILIYEQDEKKSASGSKD

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=331, Percent_Identity=51.963746223565, Blast_Score=315, Evalue=7e-86,
Organism=Escherichia coli, GI1786642, Length=423, Percent_Identity=76.3593380614657, Blast_Score=639, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=99, Percent_Identity=46.4646464646465, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71982908, Length=295, Percent_Identity=48.8135593220339, Blast_Score=272, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI71982905, Length=295, Percent_Identity=48.8135593220339, Blast_Score=271, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI71988663, Length=391, Percent_Identity=38.8746803069054, Blast_Score=250, Evalue=9e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=251, Percent_Identity=40.6374501992032, Blast_Score=175, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=429, Percent_Identity=39.8601398601399, Blast_Score=280, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24648291, Length=340, Percent_Identity=45.8823529411765, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24648289, Length=340, Percent_Identity=45.8823529411765, Blast_Score=293, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46642; Mature: 46511

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETE
CCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARLPTPKEISNFLDEYVIGQQHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTG
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEECCC
SGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVENIIQKLLQKCDYDVDKAQQGIVY
CCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCEE
IDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSN
EEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCC
ILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIP
EEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCHHHHCCCH
EFVGRLPVVTTLQELDEAALIDILTRPKNALTKQFQSLFKMEGSELEFRDEALIAIAKKA
HHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDESVVNGLSKPILIYEQDEKKSAS
HHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCHHEECHHHHHCCCCCEEEEECCCCCCCC
GSKD
CCCC
>Mature Secondary Structure 
SKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETE
CCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARLPTPKEISNFLDEYVIGQQHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTG
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEECCC
SGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVENIIQKLLQKCDYDVDKAQQGIVY
CCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCEE
IDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSN
EEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCC
ILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIP
EEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCHHHHCCCH
EFVGRLPVVTTLQELDEAALIDILTRPKNALTKQFQSLFKMEGSELEFRDEALIAIAKKA
HHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDESVVNGLSKPILIYEQDEKKSAS
HHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCHHEECHHHHHCCCCCEEEEECCCCCCCC
GSKD
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA