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The map label for this gene is oxyR [H]

Identifier: 148359361

GI number: 148359361

Start: 2112980

End: 2113870

Strand: Reverse

Name: oxyR [H]

Synonym: LPC_1259

Alternate gene names: 148359361

Gene position: 2113870-2112980 (Counterclockwise)

Preceding gene: 148359363

Following gene: 148359356

Centisome position: 59.1

GC content: 39.17

Gene sequence:

>891_bases
ATGAATTTAAGAGATTTACATTATTTTGTCATCCTGGCAGATGTAAAGCATTTTGGTGAAGCCGCTAAGAGGTGTTTTGT
AAGTCAACCCACTTTGAGTATGCAAATAAAAAAGCTGGAAGAAGAATTAGGTGTTGTGTTATTTGAGCGTACCAACAAAC
AGGTTTTACTGACTGATCAAGGCTCCAAATTATTAGATCGAACTAGAAAAATATTAATCCTGATTGATGAAATGAAAGAA
CTTGCTCGTCAGTCGGAAGATCTATTTACAGGTGAATTGCGTTTGGGGGTTATACCTACCGTATCGCCTTACATGTTGCC
CTTGGTAATGCCCGAACTTAAAAATGAGTACCCTCGCCTGAAAGTTTGGTTAATAGAGGATCAAACTCATAGGCTAATTA
CTAAATTGGAGCAAGGAGAACTGGATGTTGCTATCATGGCACTTCCAATAGATAAGCGTTTTTCATGTCAAACTTTATAT
GAAGAAAAGTTCTATTTTGCTTGCGCAAATACTCATCCTTTGGCCCAAGCCAAATCAGTTAATATCAATGATTTAAAAAA
TCAGCCGATTATGTTGCTAGAAGAAGGGCATTGCCTGAGGGAGCAAGCCATGGCCGTATGCCAATCAGCGAAAGCTGACG
ACATTGCAGATTTTACTGCCACCAGTTTGGAAACCTTGAGATTAATGGTACAAGCTGGAATGGGCGTCACTTTACTGCCC
GCTTTGTCTACACTAACTGCCTCAACTAATCATTTAAAATGTATTCCTTTTTCTGAGCCGGCACCCTCTCGTATCTTGGG
GTTATTTTGGCGAGCAGGAACGCCACGACAAGTTTGTTTTAATGCAATTGCTGAATTAATAACAAAAAATGTTCAATCCA
AATTAGCATAG

Upstream 100 bases:

>100_bases
AATCAATAATTCTGTATGTATTTTGTAAAATTTGAAAAATGATTTCTATACTGCAGATTTGTAATTTATGTCACAATAGA
TTTTTTATTATTGAGAAATT

Downstream 100 bases:

>100_bases
AAATTATTATAAATTATACGTAAATTCCTGCTTAGCTGGATGAGCTTTCATGAAGCTATTTTATGAATTTTAACTAGCAT
TCCTAACTGAGGATGATCAA

Product: hydrogen peroxide-inducible genes activator OxyR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MNLRDLHYFVILADVKHFGEAAKRCFVSQPTLSMQIKKLEEELGVVLFERTNKQVLLTDQGSKLLDRTRKILILIDEMKE
LARQSEDLFTGELRLGVIPTVSPYMLPLVMPELKNEYPRLKVWLIEDQTHRLITKLEQGELDVAIMALPIDKRFSCQTLY
EEKFYFACANTHPLAQAKSVNINDLKNQPIMLLEEGHCLREQAMAVCQSAKADDIADFTATSLETLRLMVQAGMGVTLLP
ALSTLTASTNHLKCIPFSEPAPSRILGLFWRAGTPRQVCFNAIAELITKNVQSKLA

Sequences:

>Translated_296_residues
MNLRDLHYFVILADVKHFGEAAKRCFVSQPTLSMQIKKLEEELGVVLFERTNKQVLLTDQGSKLLDRTRKILILIDEMKE
LARQSEDLFTGELRLGVIPTVSPYMLPLVMPELKNEYPRLKVWLIEDQTHRLITKLEQGELDVAIMALPIDKRFSCQTLY
EEKFYFACANTHPLAQAKSVNINDLKNQPIMLLEEGHCLREQAMAVCQSAKADDIADFTATSLETLRLMVQAGMGVTLLP
ALSTLTASTNHLKCIPFSEPAPSRILGLFWRAGTPRQVCFNAIAELITKNVQSKLA
>Mature_296_residues
MNLRDLHYFVILADVKHFGEAAKRCFVSQPTLSMQIKKLEEELGVVLFERTNKQVLLTDQGSKLLDRTRKILILIDEMKE
LARQSEDLFTGELRLGVIPTVSPYMLPLVMPELKNEYPRLKVWLIEDQTHRLITKLEQGELDVAIMALPIDKRFSCQTLY
EEKFYFACANTHPLAQAKSVNINDLKNQPIMLLEEGHCLREQAMAVCQSAKADDIADFTATSLETLRLMVQAGMGVTLLP
ALSTLTASTNHLKCIPFSEPAPSRILGLFWRAGTPRQVCFNAIAELITKNVQSKLA

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=292, Percent_Identity=45.2054794520548, Blast_Score=249, Evalue=1e-67,
Organism=Escherichia coli, GI145693105, Length=273, Percent_Identity=32.6007326007326, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1787879, Length=277, Percent_Identity=29.2418772563177, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI157672245, Length=269, Percent_Identity=30.1115241635688, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI2367136, Length=240, Percent_Identity=29.5833333333333, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788887, Length=282, Percent_Identity=29.4326241134752, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787601, Length=184, Percent_Identity=30.9782608695652, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788748, Length=246, Percent_Identity=27.2357723577236, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790208, Length=243, Percent_Identity=29.2181069958848, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787530, Length=254, Percent_Identity=24.8031496062992, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788297, Length=247, Percent_Identity=27.9352226720648, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87081904, Length=212, Percent_Identity=27.3584905660377, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787806, Length=280, Percent_Identity=24.6428571428571, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788296, Length=228, Percent_Identity=26.7543859649123, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788626, Length=240, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786401, Length=237, Percent_Identity=25.3164556962025, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788481, Length=287, Percent_Identity=23.3449477351916, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082132, Length=271, Percent_Identity=23.6162361623616, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787128, Length=160, Percent_Identity=30.625, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789204, Length=271, Percent_Identity=23.6162361623616, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33429; Mature: 33429

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRDLHYFVILADVKHFGEAAKRCFVSQPTLSMQIKKLEEELGVVLFERTNKQVLLTDQ
CCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCEEEEECCCCEEEEECC
GSKLLDRTRKILILIDEMKELARQSEDLFTGELRLGVIPTVSPYMLPLVMPELKNEYPRL
CHHHHHHCCEEEEEHHHHHHHHHHCCCCEECCEEEEECCCCCHHHHHHHHHHHCCCCCCE
KVWLIEDQTHRLITKLEQGELDVAIMALPIDKRFSCQTLYEEKFYFACANTHPLAQAKSV
EEEEEECCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCCEEEEECCCCCCCCCCCC
NINDLKNQPIMLLEEGHCLREQAMAVCQSAKADDIADFTATSLETLRLMVQAGMGVTLLP
CHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEHHH
ALSTLTASTNHLKCIPFSEPAPSRILGLFWRAGTPRQVCFNAIAELITKNVQSKLA
HHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLRDLHYFVILADVKHFGEAAKRCFVSQPTLSMQIKKLEEELGVVLFERTNKQVLLTDQ
CCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCEEEEECCCCEEEEECC
GSKLLDRTRKILILIDEMKELARQSEDLFTGELRLGVIPTVSPYMLPLVMPELKNEYPRL
CHHHHHHCCEEEEEHHHHHHHHHHCCCCEECCEEEEECCCCCHHHHHHHHHHHCCCCCCE
KVWLIEDQTHRLITKLEQGELDVAIMALPIDKRFSCQTLYEEKFYFACANTHPLAQAKSV
EEEEEECCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCCEEEEECCCCCCCCCCCC
NINDLKNQPIMLLEEGHCLREQAMAVCQSAKADDIADFTATSLETLRLMVQAGMGVTLLP
CHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEHHH
ALSTLTASTNHLKCIPFSEPAPSRILGLFWRAGTPRQVCFNAIAELITKNVQSKLA
HHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8890216 [H]