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The map label for this gene is yuxL [H]

Identifier: 148359176

GI number: 148359176

Start: 1880972

End: 1882942

Strand: Reverse

Name: yuxL [H]

Synonym: LPC_1070

Alternate gene names: 148359176

Gene position: 1882942-1880972 (Counterclockwise)

Preceding gene: 148359177

Following gene: 148359174

Centisome position: 52.65

GC content: 38.71

Gene sequence:

>1971_bases
ATGAAGGGGGTATGCCTGGGTCTAATTATTTGTCTTGTTGTATTTCATGATGGATGGGCTGGGAAGCGTTTGCCAGAACT
TAATGATCTTTATCGTATACAAGATATCAGCGAGCCAGATCTGTCACCAGATGGAAAATGGGTTGCCTATACCGTATCCC
AATTAAATGCCAAAGATAACATTTCCACGACTGAGGTATGGAAAGTATCAGTGGATAGTAAATCCAGTCAACGAATTACC
TTTGCAGAAGATTCATCAAGCTCGCTACCCAAATGGAGTCCTAATGGTAAATGGTTAGCTTATTTATCCGATGGCGGAAA
AGAGGGTACGACACAAATTTGGATAGCATCTGTCCAGGATAATAAAGAACATCAATTAACTCATATTGATGGCGAAGTGA
GCGATTTTACATGGTCCCCAGATTCTAACAGGATTGCATTTATAGCTCAGAAGAGTGATCCATCTAATGAGGAAGAACAA
CCCATAGTTGTAGATAGATATCAATTTAAGGTTGATGGTGTCGGTTATCTTGGTAAGGGAAGAGATCATTTATATTTGGT
TGAACTTAAGAGTAAGGCTATTACTCAACTGACTGATGGAAATCATGATGAATATTTACCGGCCTGGTCACCTGATGGAA
AATACATCGCGTTTGTCACAAAGCGTGGAAAAGATCCGGATAGGCATTTTAATTATGATATTTATTTGATCGAACCCAAG
TCTGGGGCAAAAGAGCACCAACTCACTCATTTCCCCGGTAGTGATATGAATCCTGATTACGATTCAAATCTTTCCTGGAG
CCCGGATAGTTCAAAAATAGCTTATCTTCGCAGTAATGAACATCAATGGACCTATTATTCGCCCAATCAATTGGCAATTA
TTGATATCAATACTAAAGATGAGAAAATCATTGCACCTCGGGATAATTGGTATTACAAGCCAAAATGGTCTCAAGATGGC
AAATTTATTTATGCATTAATAGAAGAAAGCAGAAACACCTATTTGAATCGCATAGACATTCATTCCGGCCAGATAAAAAA
ATTGACAGGCGGCTTGCGCTATGACATGGATTATTCACTTGCCAAAGGGAAAATTATTTTGTTAACAACAGATGATACAC
ATCCCTCTGAATTATTTATTTTGAATTCCGGATTAATTCCTTTAACACAACATAATCAAAAGCTATTGGATGAAGTTAAA
TTTCAACCCGCAGAAGACATACAGTGCAATAGCTTTGATGGAACAAGAGTTGATGGATTATTAATGAAGCCAGCGGAATA
CCAGCCGGGTATTTTATTTCCTGGTTTTGTCTATCTGCATGGAGGACCAGTCTATCAATTTAGCCATGAATTTAACTTTG
ATATGCAGTGGATAGCAGCCAATAATTATGCCGTTATTGCTCCTAATCCAAGAGGGAGTTCCGGAAGGGGGTTTCATTAT
GCAAAAGCAATTTTTGCAGATTGGGGTAATTTGGATGTAAAAGACATATTGGCTTCTGTTGATTATGTCATAGGGAAGGG
AATGGTTGATCCGAATCGTTTGGGAATAGGCGGATGGAGTTACGGAGGAATGCTAACCAATTATGTCATAGCTACAGATA
GCCGTTTCAAAGCGGCTATATCAGGTGCTGGAGCAGCGAATATTTTAGCTGGTTATGGTGTCGATCAATATACCCCGGAA
TACGAGCTGGAATTAGGGAAGCCCTGGACCAACCCTGAATTGTATCTAAAATTAAGCTACCCTTTTCTTAAAGCGAATAA
TATAAAAACACCTACATTATTTTTGTGCAGTGGCTTGGATTTTAATGTTCCTTGTGTTGGGTCAGAACAATTATACCAAG
CTTTGAAATCACTCGATGTGCCCACACAGCTGGTTATTTACCCCAATGAATATCATACTTTGGAGAAACCAAGCTTTGCC
ATCGACAGATTAAAAAGATATACCAACTGGCTAGATACTTATGTTAAATAA

Upstream 100 bases:

>100_bases
TGTTTGCTGATTGCAGGAAAAATCATATATAACAAATTTATTCTATACTTTTTAAGGCACTATAAATCTCTGATTTTTCA
GCATAATAAGGATGATTGTC

Downstream 100 bases:

>100_bases
CAATCCTGCCTAGTCGGTCAAAACAAGATGGTAATGAGTCCAATAATTAGAAAAGCACATGCAGCGACAGCATGAATTAT
TTTCATGGGAATTTTATGGG

Product: acylaminoacyl peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 656; Mature: 656

Protein sequence:

>656_residues
MKGVCLGLIICLVVFHDGWAGKRLPELNDLYRIQDISEPDLSPDGKWVAYTVSQLNAKDNISTTEVWKVSVDSKSSQRIT
FAEDSSSSLPKWSPNGKWLAYLSDGGKEGTTQIWIASVQDNKEHQLTHIDGEVSDFTWSPDSNRIAFIAQKSDPSNEEEQ
PIVVDRYQFKVDGVGYLGKGRDHLYLVELKSKAITQLTDGNHDEYLPAWSPDGKYIAFVTKRGKDPDRHFNYDIYLIEPK
SGAKEHQLTHFPGSDMNPDYDSNLSWSPDSSKIAYLRSNEHQWTYYSPNQLAIIDINTKDEKIIAPRDNWYYKPKWSQDG
KFIYALIEESRNTYLNRIDIHSGQIKKLTGGLRYDMDYSLAKGKIILLTTDDTHPSELFILNSGLIPLTQHNQKLLDEVK
FQPAEDIQCNSFDGTRVDGLLMKPAEYQPGILFPGFVYLHGGPVYQFSHEFNFDMQWIAANNYAVIAPNPRGSSGRGFHY
AKAIFADWGNLDVKDILASVDYVIGKGMVDPNRLGIGGWSYGGMLTNYVIATDSRFKAAISGAGAANILAGYGVDQYTPE
YELELGKPWTNPELYLKLSYPFLKANNIKTPTLFLCSGLDFNVPCVGSEQLYQALKSLDVPTQLVIYPNEYHTLEKPSFA
IDRLKRYTNWLDTYVK

Sequences:

>Translated_656_residues
MKGVCLGLIICLVVFHDGWAGKRLPELNDLYRIQDISEPDLSPDGKWVAYTVSQLNAKDNISTTEVWKVSVDSKSSQRIT
FAEDSSSSLPKWSPNGKWLAYLSDGGKEGTTQIWIASVQDNKEHQLTHIDGEVSDFTWSPDSNRIAFIAQKSDPSNEEEQ
PIVVDRYQFKVDGVGYLGKGRDHLYLVELKSKAITQLTDGNHDEYLPAWSPDGKYIAFVTKRGKDPDRHFNYDIYLIEPK
SGAKEHQLTHFPGSDMNPDYDSNLSWSPDSSKIAYLRSNEHQWTYYSPNQLAIIDINTKDEKIIAPRDNWYYKPKWSQDG
KFIYALIEESRNTYLNRIDIHSGQIKKLTGGLRYDMDYSLAKGKIILLTTDDTHPSELFILNSGLIPLTQHNQKLLDEVK
FQPAEDIQCNSFDGTRVDGLLMKPAEYQPGILFPGFVYLHGGPVYQFSHEFNFDMQWIAANNYAVIAPNPRGSSGRGFHY
AKAIFADWGNLDVKDILASVDYVIGKGMVDPNRLGIGGWSYGGMLTNYVIATDSRFKAAISGAGAANILAGYGVDQYTPE
YELELGKPWTNPELYLKLSYPFLKANNIKTPTLFLCSGLDFNVPCVGSEQLYQALKSLDVPTQLVIYPNEYHTLEKPSFA
IDRLKRYTNWLDTYVK
>Mature_656_residues
MKGVCLGLIICLVVFHDGWAGKRLPELNDLYRIQDISEPDLSPDGKWVAYTVSQLNAKDNISTTEVWKVSVDSKSSQRIT
FAEDSSSSLPKWSPNGKWLAYLSDGGKEGTTQIWIASVQDNKEHQLTHIDGEVSDFTWSPDSNRIAFIAQKSDPSNEEEQ
PIVVDRYQFKVDGVGYLGKGRDHLYLVELKSKAITQLTDGNHDEYLPAWSPDGKYIAFVTKRGKDPDRHFNYDIYLIEPK
SGAKEHQLTHFPGSDMNPDYDSNLSWSPDSSKIAYLRSNEHQWTYYSPNQLAIIDINTKDEKIIAPRDNWYYKPKWSQDG
KFIYALIEESRNTYLNRIDIHSGQIKKLTGGLRYDMDYSLAKGKIILLTTDDTHPSELFILNSGLIPLTQHNQKLLDEVK
FQPAEDIQCNSFDGTRVDGLLMKPAEYQPGILFPGFVYLHGGPVYQFSHEFNFDMQWIAANNYAVIAPNPRGSSGRGFHY
AKAIFADWGNLDVKDILASVDYVIGKGMVDPNRLGIGGWSYGGMLTNYVIATDSRFKAAISGAGAANILAGYGVDQYTPE
YELELGKPWTNPELYLKLSYPFLKANNIKTPTLFLCSGLDFNVPCVGSEQLYQALKSLDVPTQLVIYPNEYHTLEKPSFA
IDRLKRYTNWLDTYVK

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=372, Percent_Identity=23.6559139784946, Blast_Score=93, Evalue=9e-19,
Organism=Homo sapiens, GI194394146, Length=246, Percent_Identity=30.4878048780488, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI37577089, Length=246, Percent_Identity=30.0813008130081, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI18450280, Length=246, Percent_Identity=30.0813008130081, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI16933540, Length=258, Percent_Identity=26.7441860465116, Blast_Score=66, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17552908, Length=277, Percent_Identity=26.7148014440433, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17564632, Length=223, Percent_Identity=29.5964125560538, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564634, Length=223, Percent_Identity=29.5964125560538, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25144537, Length=226, Percent_Identity=25.6637168141593, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI25144540, Length=219, Percent_Identity=26.027397260274, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17550672, Length=235, Percent_Identity=28.0851063829787, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25149159, Length=371, Percent_Identity=25.3369272237197, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508017, Length=224, Percent_Identity=29.4642857142857, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17508019, Length=224, Percent_Identity=29.4642857142857, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45550825, Length=231, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI45553511, Length=231, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI45551969, Length=232, Percent_Identity=28.448275862069, Blast_Score=79, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 74180; Mature: 74180

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGVCLGLIICLVVFHDGWAGKRLPELNDLYRIQDISEPDLSPDGKWVAYTVSQLNAKDN
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCCCCCCCCCCCEEEEEEEECCCCCC
ISTTEVWKVSVDSKSSQRITFAEDSSSSLPKWSPNGKWLAYLSDGGKEGTTQIWIASVQD
CCEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECC
NKEHQLTHIDGEVSDFTWSPDSNRIAFIAQKSDPSNEEEQPIVVDRYQFKVDGVGYLGKG
CCCCEEEEECCCCCCEEECCCCCEEEEEEECCCCCCCCCCCEEEEEEEEEECCEEEECCC
RDHLYLVELKSKAITQLTDGNHDEYLPAWSPDGKYIAFVTKRGKDPDRHFNYDIYLIEPK
CCEEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHCCEEEEEECCC
SGAKEHQLTHFPGSDMNPDYDSNLSWSPDSSKIAYLRSNEHQWTYYSPNQLAIIDINTKD
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCEEEEEEECCCC
EKIIAPRDNWYYKPKWSQDGKFIYALIEESRNTYLNRIDIHSGQIKKLTGGLRYDMDYSL
CEEECCCCCCEECCCCCCCCCEEEEEEECCCCCEEEEEECCCCCEEECCCCEEECCCCEE
AKGKIILLTTDDTHPSELFILNSGLIPLTQHNQKLLDEVKFQPAEDIQCNSFDGTRVDGL
CCCEEEEEECCCCCCCEEEEEECCCEEECCCCHHHHHHHCCCCCCCCEECCCCCCCCCEE
LMKPAEYQPGILFPGFVYLHGGPVYQFSHEFNFDMQWIAANNYAVIAPNPRGSSGRGFHY
EECCCCCCCCEECCCEEEEECCEEEEEECCCCCEEEEEEECCEEEECCCCCCCCCCCEEE
AKAIFADWGNLDVKDILASVDYVIGKGMVDPNRLGIGGWSYGGMLTNYVIATDSRFKAAI
EEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCEEEEEEEEECCCEEEEE
SGAGAANILAGYGVDQYTPEYELELGKPWTNPELYLKLSYPFLKANNIKTPTLFLCSGLD
CCCCHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCEEECCCCCCCEEEEECCCC
FNVPCVGSEQLYQALKSLDVPTQLVIYPNEYHTLEKPSFAIDRLKRYTNWLDTYVK
CCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKGVCLGLIICLVVFHDGWAGKRLPELNDLYRIQDISEPDLSPDGKWVAYTVSQLNAKDN
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCCCCCCCCCCCEEEEEEEECCCCCC
ISTTEVWKVSVDSKSSQRITFAEDSSSSLPKWSPNGKWLAYLSDGGKEGTTQIWIASVQD
CCEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECC
NKEHQLTHIDGEVSDFTWSPDSNRIAFIAQKSDPSNEEEQPIVVDRYQFKVDGVGYLGKG
CCCCEEEEECCCCCCEEECCCCCEEEEEEECCCCCCCCCCCEEEEEEEEEECCEEEECCC
RDHLYLVELKSKAITQLTDGNHDEYLPAWSPDGKYIAFVTKRGKDPDRHFNYDIYLIEPK
CCEEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHCCEEEEEECCC
SGAKEHQLTHFPGSDMNPDYDSNLSWSPDSSKIAYLRSNEHQWTYYSPNQLAIIDINTKD
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCEEEEEEECCCC
EKIIAPRDNWYYKPKWSQDGKFIYALIEESRNTYLNRIDIHSGQIKKLTGGLRYDMDYSL
CEEECCCCCCEECCCCCCCCCEEEEEEECCCCCEEEEEECCCCCEEECCCCEEECCCCEE
AKGKIILLTTDDTHPSELFILNSGLIPLTQHNQKLLDEVKFQPAEDIQCNSFDGTRVDGL
CCCEEEEEECCCCCCCEEEEEECCCEEECCCCHHHHHHHCCCCCCCCEECCCCCCCCCEE
LMKPAEYQPGILFPGFVYLHGGPVYQFSHEFNFDMQWIAANNYAVIAPNPRGSSGRGFHY
EECCCCCCCCEECCCEEEEECCEEEEEECCCCCEEEEEEECCEEEECCCCCCCCCCCEEE
AKAIFADWGNLDVKDILASVDYVIGKGMVDPNRLGIGGWSYGGMLTNYVIATDSRFKAAI
EEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCEEEEEEEEECCCEEEEE
SGAGAANILAGYGVDQYTPEYELELGKPWTNPELYLKLSYPFLKANNIKTPTLFLCSGLD
CCCCHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCEEECCCCCCCEEEEECCCC
FNVPCVGSEQLYQALKSLDVPTQLVIYPNEYHTLEKPSFAIDRLKRYTNWLDTYVK
CCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]