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The map label for this gene is efp

Identifier: 148358500

GI number: 148358500

Start: 395898

End: 396467

Strand: Reverse

Name: efp

Synonym: LPC_0366

Alternate gene names: 148358500

Gene position: 396467-395898 (Counterclockwise)

Preceding gene: 148358502

Following gene: 148358495

Centisome position: 11.09

GC content: 43.16

Gene sequence:

>570_bases
ATGGCAGTCTATAGCACAAATGAATTTAAAAACGGCTTAAAAGTAATGGTTGATGATGCTCCGTGCAGCATTCTTGACTG
TGAATTTGTAAAACCTGGAAAAGGTCAAGCATTCACCCGTATTAAAATTCGCAATCTAAAAACCGGGCGCGTTGTGGAAC
GTACCTTTAAATCTGGGGACACCTTACCATCTGCTGATGTGGCTGACGTAGAAATGCAGTATCTATATAACGATGGGGAG
TATTGGCATTTTATGGTTCCAGATACGTTTGAACAATATGCCGTGACTGAAAACGTATTAGCCGATGCAGCACAATGGTT
AAAGGAACAGGACGTTTGTGTACTTACTCTATGGAATAATGAGCCTATACAGGTCACGCCACCCAATTTTGTCATTTTGG
CAATCACCGAAACAGATCCTGGATTAAAAGGAGACACTTCTGGCGGAGGCGGAAAGCCAGCTACATTGGAAACAGGTGCC
GTTGTTCGTGTACCATTGTTTGTTCAAACTGGCGAACTGATTAAGGTAGACACGCGCAAAGGCGAATATGTGTCTCGCGC
TAAAGAGTAA

Upstream 100 bases:

>100_bases
TTTTGCCAACTCAAAGAGGTATCTCGCATTAAAGTTACAGACTTGATAAACTGTGCGAACTTTAGCGAAAATACAGCAAA
ATCTCAACTATGGAGCAGAA

Downstream 100 bases:

>100_bases
TTATCAGCAGGAATAGCCTTCATTTGATTTGAAGGCTTGCCTTCTCACGGAAATTAGAAATCGTAATCTCCACCCCAATA
TCCATAAGGACCTACAAAAG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MAVYSTNEFKNGLKVMVDDAPCSILDCEFVKPGKGQAFTRIKIRNLKTGRVVERTFKSGDTLPSADVADVEMQYLYNDGE
YWHFMVPDTFEQYAVTENVLADAAQWLKEQDVCVLTLWNNEPIQVTPPNFVILAITETDPGLKGDTSGGGGKPATLETGA
VVRVPLFVQTGELIKVDTRKGEYVSRAKE

Sequences:

>Translated_189_residues
MAVYSTNEFKNGLKVMVDDAPCSILDCEFVKPGKGQAFTRIKIRNLKTGRVVERTFKSGDTLPSADVADVEMQYLYNDGE
YWHFMVPDTFEQYAVTENVLADAAQWLKEQDVCVLTLWNNEPIQVTPPNFVILAITETDPGLKGDTSGGGGKPATLETGA
VVRVPLFVQTGELIKVDTRKGEYVSRAKE
>Mature_188_residues
AVYSTNEFKNGLKVMVDDAPCSILDCEFVKPGKGQAFTRIKIRNLKTGRVVERTFKSGDTLPSADVADVEMQYLYNDGEY
WHFMVPDTFEQYAVTENVLADAAQWLKEQDVCVLTLWNNEPIQVTPPNFVILAITETDPGLKGDTSGGGGKPATLETGAV
VRVPLFVQTGELIKVDTRKGEYVSRAKE

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=188, Percent_Identity=62.7659574468085, Blast_Score=254, Evalue=2e-69,
Organism=Escherichia coli, GI87082061, Length=186, Percent_Identity=30.1075268817204, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_LEGPA (Q5X888)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_122705.1
- ProteinModelPortal:   Q5X888
- SMR:   Q5X888
- STRING:   Q5X888
- GeneID:   3119468
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp0365
- LegioList:   lpp0365
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- BioCyc:   LPNE297246:LPP0365-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20927; Mature: 20796

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVYSTNEFKNGLKVMVDDAPCSILDCEFVKPGKGQAFTRIKIRNLKTGRVVERTFKSGD
CCEECCCCCCCCCEEEECCCCCCEEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHCCC
TLPSADVADVEMQYLYNDGEYWHFMVPDTFEQYAVTENVLADAAQWLKEQDVCVLTLWNN
CCCCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
EPIQVTPPNFVILAITETDPGLKGDTSGGGGKPATLETGAVVRVPLFVQTGELIKVDTRK
CCEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEEEEECCCEEEEECCC
GEYVSRAKE
CCHHHHCCC
>Mature Secondary Structure 
AVYSTNEFKNGLKVMVDDAPCSILDCEFVKPGKGQAFTRIKIRNLKTGRVVERTFKSGD
CEECCCCCCCCCEEEECCCCCCEEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHCCC
TLPSADVADVEMQYLYNDGEYWHFMVPDTFEQYAVTENVLADAAQWLKEQDVCVLTLWNN
CCCCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
EPIQVTPPNFVILAITETDPGLKGDTSGGGGKPATLETGAVVRVPLFVQTGELIKVDTRK
CCEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEEEEECCCEEEEECCC
GEYVSRAKE
CCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA