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The map label for this gene is ndhF [H]

Identifier: 148358432

GI number: 148358432

Start: 310244

End: 311764

Strand: Reverse

Name: ndhF [H]

Synonym: LPC_0298

Alternate gene names: 148358432

Gene position: 311764-310244 (Counterclockwise)

Preceding gene: 148358438

Following gene: 148358431

Centisome position: 8.72

GC content: 38.2

Gene sequence:

>1521_bases
GTGGATAAACTTTTAAATGGGTTATCGATTTCACTCATGCTATCACCCTTGATAGCGATGCTATTCTATAGCTTGTTAGG
AAAAACAAGAAATATTCAAGCAACTTATTACGGTACCACAGTTATAGGTTTTGGTTTTGGATTGAGTCTCTTGGCATTAA
TTGTTTCCGCAAATACTGTAAACCAAAACAGTTATTTTTTATTTCATGCCAGCACACTAAGCCTCTTACTAAGCACATTA
ATATTATTCATCAGCTTTATTATCCACCGTTTTTCCCTACGATACATGCATGGCGACAAGTGCTACCGACGTTATTTTTT
CAAACTTTCAGCCATAACTTTAACAACTGTTGTGATGGCTTTAGCAGACAATCTTTTATTGTTCTGGCTTGCCTGGTCAG
CTAGTAACTTGCTCTTGATAAACCTCATGATTCATAAGTCACAATGGAAAGCAGCCTACAACTCAGGGATACTGACTTTA
AAAACATTATTACCAGGAAGCTTGTTGCTTATCACTGCATTTTGGATTCTTTTTACATTAAACAATACTCTGTCAATTGA
AACAATAACCAGCGAAGTGAGCAATAAGTCATCCCCTGCTATTGCTGTGGCACTTGGATTTATTATCTTAACAGCGATGA
CACAATCCGCCATATGGCCTTTTCATCGCTGGCTAATAAGCTCATTAAACTCTCCAACACCGGTATCCGCTCTAATGCAT
GCTGGGTTAGTTAATGGAGGGGGCTTTCTGATTGTTAAATTTGCTCCTTTGTTTGTCATGCAAACAAATTTATTAACCAT
TTTATTCATTTTCGGTGCACTAACTGCTTTATTAGGTACTCTCTGGAAACTATTGCAGTGGAATATCAAAAGTATGCTTG
CCAGTTCCACCATGGCACAAATGGGTTTTATGATAATGCAATGTGGGTTAGGACTTTTCCCGGCCGCTATCGCCCATCTA
TGCTGGCATGGCTTGTTTAAATCCTATCTTTTTCTCAATTCAGGATCTGCTGTCCAACAAAAGAAATATCAAAATAAATC
ACGTCCCGAAAAATTGACAACTTTATTGACTGCATTTTTTGGAGGACTTTTGGGAATGTATGGTTTTGCCCTTATCACAG
GCAAACCCATCTTATCTCTCCATGCGTCCACCTTTCTTTTAGGTTTCGCATTCATCACAGGGACACAATTCACTCTGGGC
TTGATTGCATATGAGAAGCATTTCAAAAAGGTAATTTTAGCCTTGGCTTTAGTTTTCTCAATTGGGATTTTTTATGGGGG
AAGTATACATCTGATCGAGTCACTCTTACCTGATCTAACAGGATTTCCTCAACACCAATTAAGCAGCTTACAAGTCTTAA
CTCTGATTGTCTTCTTTTCCCTTTGGCTTGTATTCAGCATGGGATTATTCAAAAAAATCAGAGAGACCAGACTTTGGGAT
TGGTTTTACATGTACATGTTTAACGCAAGTACGCCTCACCCCAAAACCATTACGGCAAATCGCCATACTTATTACTATTA
A

Upstream 100 bases:

>100_bases
AGTTTTTCTAATAGTTTAAATCATTATTTTTAATTTTACTTATATTAACATATCTAATATATTTCCACAATAATAACAGA
TTTTCTAATGGGGAATTAAT

Downstream 100 bases:

>100_bases
GAAAAGGAGCCAACATGAGTAGCCACATCACACTAATCAAAACTAACACGAACAATGAAAATCAAATGACCCAATTTAAC
TACAAAGTCGATAATGATGT

Product: NADH dehydrogenase subunit 5

Products: NA

Alternate protein names: NADH dehydrogenase subunit 5 [H]

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MDKLLNGLSISLMLSPLIAMLFYSLLGKTRNIQATYYGTTVIGFGFGLSLLALIVSANTVNQNSYFLFHASTLSLLLSTL
ILFISFIIHRFSLRYMHGDKCYRRYFFKLSAITLTTVVMALADNLLLFWLAWSASNLLLINLMIHKSQWKAAYNSGILTL
KTLLPGSLLLITAFWILFTLNNTLSIETITSEVSNKSSPAIAVALGFIILTAMTQSAIWPFHRWLISSLNSPTPVSALMH
AGLVNGGGFLIVKFAPLFVMQTNLLTILFIFGALTALLGTLWKLLQWNIKSMLASSTMAQMGFMIMQCGLGLFPAAIAHL
CWHGLFKSYLFLNSGSAVQQKKYQNKSRPEKLTTLLTAFFGGLLGMYGFALITGKPILSLHASTFLLGFAFITGTQFTLG
LIAYEKHFKKVILALALVFSIGIFYGGSIHLIESLLPDLTGFPQHQLSSLQVLTLIVFFSLWLVFSMGLFKKIRETRLWD
WFYMYMFNASTPHPKTITANRHTYYY

Sequences:

>Translated_506_residues
MDKLLNGLSISLMLSPLIAMLFYSLLGKTRNIQATYYGTTVIGFGFGLSLLALIVSANTVNQNSYFLFHASTLSLLLSTL
ILFISFIIHRFSLRYMHGDKCYRRYFFKLSAITLTTVVMALADNLLLFWLAWSASNLLLINLMIHKSQWKAAYNSGILTL
KTLLPGSLLLITAFWILFTLNNTLSIETITSEVSNKSSPAIAVALGFIILTAMTQSAIWPFHRWLISSLNSPTPVSALMH
AGLVNGGGFLIVKFAPLFVMQTNLLTILFIFGALTALLGTLWKLLQWNIKSMLASSTMAQMGFMIMQCGLGLFPAAIAHL
CWHGLFKSYLFLNSGSAVQQKKYQNKSRPEKLTTLLTAFFGGLLGMYGFALITGKPILSLHASTFLLGFAFITGTQFTLG
LIAYEKHFKKVILALALVFSIGIFYGGSIHLIESLLPDLTGFPQHQLSSLQVLTLIVFFSLWLVFSMGLFKKIRETRLWD
WFYMYMFNASTPHPKTITANRHTYYY
>Mature_506_residues
MDKLLNGLSISLMLSPLIAMLFYSLLGKTRNIQATYYGTTVIGFGFGLSLLALIVSANTVNQNSYFLFHASTLSLLLSTL
ILFISFIIHRFSLRYMHGDKCYRRYFFKLSAITLTTVVMALADNLLLFWLAWSASNLLLINLMIHKSQWKAAYNSGILTL
KTLLPGSLLLITAFWILFTLNNTLSIETITSEVSNKSSPAIAVALGFIILTAMTQSAIWPFHRWLISSLNSPTPVSALMH
AGLVNGGGFLIVKFAPLFVMQTNLLTILFIFGALTALLGTLWKLLQWNIKSMLASSTMAQMGFMIMQCGLGLFPAAIAHL
CWHGLFKSYLFLNSGSAVQQKKYQNKSRPEKLTTLLTAFFGGLLGMYGFALITGKPILSLHASTFLLGFAFITGTQFTLG
LIAYEKHFKKVILALALVFSIGIFYGGSIHLIESLLPDLTGFPQHQLSSLQVLTLIVFFSLWLVFSMGLFKKIRETRLWD
WFYMYMFNASTPHPKTITANRHTYYY

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=320, Percent_Identity=28.4375, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1788614, Length=282, Percent_Identity=33.6879432624113, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1788831, Length=350, Percent_Identity=26.5714285714286, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788827, Length=228, Percent_Identity=27.6315789473684, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 56578; Mature: 56578

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLLNGLSISLMLSPLIAMLFYSLLGKTRNIQATYYGTTVIGFGFGLSLLALIVSANTV
CCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCC
NQNSYFLFHASTLSLLLSTLILFISFIIHRFSLRYMHGDKCYRRYFFKLSAITLTTVVMA
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LADNLLLFWLAWSASNLLLINLMIHKSQWKAAYNSGILTLKTLLPGSLLLITAFWILFTL
HHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHCCCCEEEHHHCCCHHHHHHHHHHHHHH
NNTLSIETITSEVSNKSSPAIAVALGFIILTAMTQSAIWPFHRWLISSLNSPTPVSALMH
CCCEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AGLVNGGGFLIVKFAPLFVMQTNLLTILFIFGALTALLGTLWKLLQWNIKSMLASSTMAQ
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGFMIMQCGLGLFPAAIAHLCWHGLFKSYLFLNSGSAVQQKKYQNKSRPEKLTTLLTAFF
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCHHHHHHHHHHHH
GGLLGMYGFALITGKPILSLHASTFLLGFAFITGTQFTLGLIAYEKHFKKVILALALVFS
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
IGIFYGGSIHLIESLLPDLTGFPQHQLSSLQVLTLIVFFSLWLVFSMGLFKKIRETRLWD
HHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WFYMYMFNASTPHPKTITANRHTYYY
HHHHHHCCCCCCCCCEEECCCCCCCC
>Mature Secondary Structure
MDKLLNGLSISLMLSPLIAMLFYSLLGKTRNIQATYYGTTVIGFGFGLSLLALIVSANTV
CCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCC
NQNSYFLFHASTLSLLLSTLILFISFIIHRFSLRYMHGDKCYRRYFFKLSAITLTTVVMA
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LADNLLLFWLAWSASNLLLINLMIHKSQWKAAYNSGILTLKTLLPGSLLLITAFWILFTL
HHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHCCCCEEEHHHCCCHHHHHHHHHHHHHH
NNTLSIETITSEVSNKSSPAIAVALGFIILTAMTQSAIWPFHRWLISSLNSPTPVSALMH
CCCEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AGLVNGGGFLIVKFAPLFVMQTNLLTILFIFGALTALLGTLWKLLQWNIKSMLASSTMAQ
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGFMIMQCGLGLFPAAIAHLCWHGLFKSYLFLNSGSAVQQKKYQNKSRPEKLTTLLTAFF
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCHHHHHHHHHHHH
GGLLGMYGFALITGKPILSLHASTFLLGFAFITGTQFTLGLIAYEKHFKKVILALALVFS
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
IGIFYGGSIHLIESLLPDLTGFPQHQLSSLQVLTLIVFFSLWLVFSMGLFKKIRETRLWD
HHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WFYMYMFNASTPHPKTITANRHTYYY
HHHHHHCCCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]