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The map label for this gene is yegE [H]

Identifier: 148358372

GI number: 148358372

Start: 250707

End: 251585

Strand: Reverse

Name: yegE [H]

Synonym: LPC_0236

Alternate gene names: 148358372

Gene position: 251585-250707 (Counterclockwise)

Preceding gene: 148358373

Following gene: 148358366

Centisome position: 7.03

GC content: 35.04

Gene sequence:

>879_bases
ATGCTTACAAACATTGAAAGAGCAAAACTTCAATTAATTGATGAAACCAGCGATATGGTCATTATAACCAAAGCGGATCC
ACTTGATGCACCTAATGGTCCGGAAGTGGTTTGGGTAAATAAAGCCTTTGAAAAAATTTCAAAATATAAAGCCAATGAAA
TTATTGGCCAAACACCACGTATCCTTCAAGGTAAAGAAACCAATCAAAACACATTAAAAATGATAAGAGAAGCAATGAAA
GCTCAAACGAGTATCAATGTGGAGTTATTAAATTATACTAAGGATGGGACACCTTATTGGATTAATTTTTCAATAGTATA
TTTGAGAGACGGGCAGGGTAATTTATGTTATTTGGGTGCAATAGAAAGAGATATCACCGCAATCAAGAATTTAAATTTTC
AATTATCTGAAAAAGCAAAGACTGATCCGCTTACCAACGTTTACAATCAGGAAAATTTCTTCATCGCAGGGAATGAAGCT
ATTAAAAATTTTCATCAAAACCAGGAAGCAGTTGGATTATTATTTTTCGATGTGGATGATTTTAAAGGAATAAACGATAC
GCAAGGGCATATCTATGGCGATAAGATACTAAAAAAAGTTGCCCAGGAATCTTTAAAGCTTGTCCGTAAAACGGATAACG
TATTTCGATATGGCGGCGATGAGTTTGCTATTATTTTTTCAGGCATTGATGTGAAAATCCTGGAAAGAAAAGCACAACAA
CTACAAAAAAAGCTGGCAAAATCTCACATCTCAGTGAGCATTGGAGGGACTATTTCAAAGCAAAGTGACAAATCGATAAA
TACCCTCTTGGCGAGAGCGGATGAAGCACTCTATTACGTCAAAGCCAACAAAAAAGGGTTGTTTTTTATCAGAGAATAA

Upstream 100 bases:

>100_bases
ATCAAGGTTTTTTGTTTGAGAGACCTATGCCTTACGAAAAAATACCCGACTATATCAAAGCAAGCGCATAAAAATGGATT
GGCTATTGGATGCATGACAA

Downstream 100 bases:

>100_bases
TCACATTTTGACGCTGCTAAATTACGAGGAAATTAAACCCGGAGACATTCAATTCTTTGAAAATGACCTCATTATTTAAT
TAAGACCCCATCATGAATTA

Product: GGDEF/EAL domain-containing sensory box protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MLTNIERAKLQLIDETSDMVIITKADPLDAPNGPEVVWVNKAFEKISKYKANEIIGQTPRILQGKETNQNTLKMIREAMK
AQTSINVELLNYTKDGTPYWINFSIVYLRDGQGNLCYLGAIERDITAIKNLNFQLSEKAKTDPLTNVYNQENFFIAGNEA
IKNFHQNQEAVGLLFFDVDDFKGINDTQGHIYGDKILKKVAQESLKLVRKTDNVFRYGGDEFAIIFSGIDVKILERKAQQ
LQKKLAKSHISVSIGGTISKQSDKSINTLLARADEALYYVKANKKGLFFIRE

Sequences:

>Translated_292_residues
MLTNIERAKLQLIDETSDMVIITKADPLDAPNGPEVVWVNKAFEKISKYKANEIIGQTPRILQGKETNQNTLKMIREAMK
AQTSINVELLNYTKDGTPYWINFSIVYLRDGQGNLCYLGAIERDITAIKNLNFQLSEKAKTDPLTNVYNQENFFIAGNEA
IKNFHQNQEAVGLLFFDVDDFKGINDTQGHIYGDKILKKVAQESLKLVRKTDNVFRYGGDEFAIIFSGIDVKILERKAQQ
LQKKLAKSHISVSIGGTISKQSDKSINTLLARADEALYYVKANKKGLFFIRE
>Mature_292_residues
MLTNIERAKLQLIDETSDMVIITKADPLDAPNGPEVVWVNKAFEKISKYKANEIIGQTPRILQGKETNQNTLKMIREAMK
AQTSINVELLNYTKDGTPYWINFSIVYLRDGQGNLCYLGAIERDITAIKNLNFQLSEKAKTDPLTNVYNQENFFIAGNEA
IKNFHQNQEAVGLLFFDVDDFKGINDTQGHIYGDKILKKVAQESLKLVRKTDNVFRYGGDEFAIIFSGIDVKILERKAQQ
LQKKLAKSHISVSIGGTISKQSDKSINTLLARADEALYYVKANKKGLFFIRE

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=270, Percent_Identity=24.0740740740741, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787541, Length=261, Percent_Identity=25.2873563218391, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87081881, Length=168, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693134, Length=168, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787262, Length=166, Percent_Identity=27.710843373494, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082007, Length=180, Percent_Identity=30.5555555555556, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786584, Length=161, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787802, Length=179, Percent_Identity=30.1675977653631, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081974, Length=154, Percent_Identity=31.1688311688312, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787056, Length=117, Percent_Identity=38.4615384615385, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787816, Length=129, Percent_Identity=28.6821705426357, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788956, Length=116, Percent_Identity=34.4827586206897, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 33048; Mature: 33048

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTNIERAKLQLIDETSDMVIITKADPLDAPNGPEVVWVNKAFEKISKYKANEIIGQTPR
CCCCCCHHHEEEEECCCCEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCC
ILQGKETNQNTLKMIREAMKAQTSINVELLNYTKDGTPYWINFSIVYLRDGQGNLCYLGA
CCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEEEEEEEECCCCCEEEEEC
IERDITAIKNLNFQLSEKAKTDPLTNVYNQENFFIAGNEAIKNFHQNQEAVGLLFFDVDD
HHHHHHHHHCCCEEECCCCCCCCCHHHCCCCCEEEECHHHHHHHHCCCCEEEEEEEECCC
FKGINDTQGHIYGDKILKKVAQESLKLVRKTDNVFRYGGDEFAIIFSGIDVKILERKAQQ
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEEECCCHHHHHHHHHH
LQKKLAKSHISVSIGGTISKQSDKSINTLLARADEALYYVKANKKGLFFIRE
HHHHHHHHHEEEEECCEECCCCCHHHHHHHHHCCCEEEEEEECCCEEEEEEC
>Mature Secondary Structure
MLTNIERAKLQLIDETSDMVIITKADPLDAPNGPEVVWVNKAFEKISKYKANEIIGQTPR
CCCCCCHHHEEEEECCCCEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCC
ILQGKETNQNTLKMIREAMKAQTSINVELLNYTKDGTPYWINFSIVYLRDGQGNLCYLGA
CCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEEEEEEEECCCCCEEEEEC
IERDITAIKNLNFQLSEKAKTDPLTNVYNQENFFIAGNEAIKNFHQNQEAVGLLFFDVDD
HHHHHHHHHCCCEEECCCCCCCCCHHHCCCCCEEEECHHHHHHHHCCCCEEEEEEEECCC
FKGINDTQGHIYGDKILKKVAQESLKLVRKTDNVFRYGGDEFAIIFSGIDVKILERKAQQ
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEEECCCHHHHHHHHHH
LQKKLAKSHISVSIGGTISKQSDKSINTLLARADEALYYVKANKKGLFFIRE
HHHHHHHHHEEEEECCEECCCCCHHHHHHHHHCCCEEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]