BacMap

Definition	Staphylococcus aureus subsp. aureus JH9, complete genome.
Accession	NC_009487
Length	2,906,700

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The map label for this gene is gudP [H]

Identifier: 148268945

GI number: 148268945

Start: 2682847

End: 2684124

Strand: Reverse

Name: gudP [H]

Synonym: SaurJH9_2535

Alternate gene names: 148268945

Gene position: 2684124-2682847 (Counterclockwise)

Preceding gene: 148268951

Following gene: 148268944

Centisome position: 92.34

GC content: 35.99

Gene sequence:

>1278_bases
ATGAAGGAAAAACGAACTAACGTAAGGTGGATGTTCGCGCTTGCGTTCTTCTTTATTGGGGTTATTGCGTATATGGATAG
AGCAAACATTTCATATATCGCTAAACAAATGATGGATGATTTAGGGATGACCAAACCACAATTTGGTTTATTGGCATCAT
TCTTCTCTCTAGGTTATGCATTAATGCAAGTACCATCGGGGATGTTGGCTGAAAAATTCGGTCCACGTAAGATGATTACA
ATTGCATTAGTTTGGTGGAGTGCATTTACAATCTTAACGGGTATGATTAAGAACCACGGTTTAATTTATTTAGTGAGATT
CTTATTTGGTGTGGGTGAGGCGCCAATGTATCCTTCTAATGCTGTGTTTAACTCATTTTGGTTCTCTAAAAATGAAAAAG
GTAGAGCATCAAGTGCATTATTAGCAGGATCATATTTCGGACCTGTATTAGCACCAATAGTTACAATTGCTATTGTTAAC
GCATTTAACTGGCAAGCAGTATTTTACATTTTTGGTGCAGTAGGTATTTTAATGGCTGTATTATGGGCGATTATTGCCAA
AGACTTATCTGAGCAACATAGAATGGTTAATGAAGCGGAGAAACGTTTCATTATGGAAAATCGTGATATCGTAGCTACTG
AAAAGTCATCACCACCATGGAATAATTTCTTTAAACGTTTTAGCTTCTATGCAATTGCAATTCAATACTTTGTTGTACAA
TTTATCATTACATTATTCTTAATTTGGTTACCGACGTATTTAACAGAAGTATTCCACGTTAACTTTAAAGAAATGAGCAT
TAGTTCATTACCTTGGTTATTAATGTTCTTCTTAATCTTATCAGCAGGTGCAATTTCTGACCGTGTATTAGGATTAGGTC
GTTCAAAATTCGTAGCTAGAGGTGTAATTGCAATCGCAGGATTTATTGTGTTTGCAGTTTCAATTATCTTTGCTGTACGT
ACAGGAAATTTATATGTAAGTATTTTCTGGTTATCACTAGGTCTTGGTGGTATCGGTATTTCAATGGGTATGAGTTGGGC
TGCAGCAACTGACTTAGGACGTAACTTCTCTGGTACAGTATCAGGGTGGATGAACTTATGGGGTAATATAGGTGCATTAA
TCAGTCCGCTATTAGCAGGTCTATTCGTAGAACATTTAGGTTGGACAATGACATTCCAATTGTTAATCGTTCCAGCAGTA
ATCGCTGTGATTATGTGGTTCTATGTGAAACCAGATCAACCTTTAATTGTTAGTGATGATAAAGCAATAGAAAAATAA

Upstream 100 bases:

>100_bases
ACAATTTTGTGACAAAGTAGGGGTGGACATGCCAGATGTCCGAAAATTTTAACGTTTCAGGGTAAGTTTTAAAAAATTAA
TTAGGGAAGTAGGAATAGTT

Downstream 100 bases:

>100_bases
TTTAAACAAGCAGTAAGCTTTCACATTGTTGGGGCTTATTGCTTTTTTACGTTGAAATTGAAACTTTTTAAAACAGATAT
GGTTTAAGATGAACGGGAAG

Product: major facilitator transporter

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MKEKRTNVRWMFALAFFFIGVIAYMDRANISYIAKQMMDDLGMTKPQFGLLASFFSLGYALMQVPSGMLAEKFGPRKMIT
IALVWWSAFTILTGMIKNHGLIYLVRFLFGVGEAPMYPSNAVFNSFWFSKNEKGRASSALLAGSYFGPVLAPIVTIAIVN
AFNWQAVFYIFGAVGILMAVLWAIIAKDLSEQHRMVNEAEKRFIMENRDIVATEKSSPPWNNFFKRFSFYAIAIQYFVVQ
FIITLFLIWLPTYLTEVFHVNFKEMSISSLPWLLMFFLILSAGAISDRVLGLGRSKFVARGVIAIAGFIVFAVSIIFAVR
TGNLYVSIFWLSLGLGGIGISMGMSWAAATDLGRNFSGTVSGWMNLWGNIGALISPLLAGLFVEHLGWTMTFQLLIVPAV
IAVIMWFYVKPDQPLIVSDDKAIEK

Sequences:

>Translated_425_residues
MKEKRTNVRWMFALAFFFIGVIAYMDRANISYIAKQMMDDLGMTKPQFGLLASFFSLGYALMQVPSGMLAEKFGPRKMIT
IALVWWSAFTILTGMIKNHGLIYLVRFLFGVGEAPMYPSNAVFNSFWFSKNEKGRASSALLAGSYFGPVLAPIVTIAIVN
AFNWQAVFYIFGAVGILMAVLWAIIAKDLSEQHRMVNEAEKRFIMENRDIVATEKSSPPWNNFFKRFSFYAIAIQYFVVQ
FIITLFLIWLPTYLTEVFHVNFKEMSISSLPWLLMFFLILSAGAISDRVLGLGRSKFVARGVIAIAGFIVFAVSIIFAVR
TGNLYVSIFWLSLGLGGIGISMGMSWAAATDLGRNFSGTVSGWMNLWGNIGALISPLLAGLFVEHLGWTMTFQLLIVPAV
IAVIMWFYVKPDQPLIVSDDKAIEK
>Mature_425_residues
MKEKRTNVRWMFALAFFFIGVIAYMDRANISYIAKQMMDDLGMTKPQFGLLASFFSLGYALMQVPSGMLAEKFGPRKMIT
IALVWWSAFTILTGMIKNHGLIYLVRFLFGVGEAPMYPSNAVFNSFWFSKNEKGRASSALLAGSYFGPVLAPIVTIAIVN
AFNWQAVFYIFGAVGILMAVLWAIIAKDLSEQHRMVNEAEKRFIMENRDIVATEKSSPPWNNFFKRFSFYAIAIQYFVVQ
FIITLFLIWLPTYLTEVFHVNFKEMSISSLPWLLMFFLILSAGAISDRVLGLGRSKFVARGVIAIAGFIVFAVSIIFAVR
TGNLYVSIFWLSLGLGGIGISMGMSWAAATDLGRNFSGTVSGWMNLWGNIGALISPLLAGLFVEHLGWTMTFQLLIVPAV
IAVIMWFYVKPDQPLIVSDDKAIEK

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=338, Percent_Identity=27.810650887574, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI9945322, Length=350, Percent_Identity=26, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI21322234, Length=349, Percent_Identity=26.0744985673352, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI9966811, Length=395, Percent_Identity=24.3037974683544, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI148743791, Length=354, Percent_Identity=23.728813559322, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI154350196, Length=385, Percent_Identity=24.1558441558442, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI154800443, Length=392, Percent_Identity=26.0204081632653, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI5031955, Length=249, Percent_Identity=27.710843373494, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI4885441, Length=363, Percent_Identity=23.6914600550964, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI148728191, Length=277, Percent_Identity=23.826714801444, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI223718438, Length=158, Percent_Identity=29.1139240506329, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1789515, Length=431, Percent_Identity=27.1461716937355, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI2367379, Length=399, Percent_Identity=25.31328320802, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789152, Length=448, Percent_Identity=28.125, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI87082320, Length=398, Percent_Identity=25.1256281407035, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI2367193, Length=425, Percent_Identity=24, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082071, Length=433, Percent_Identity=22.4018475750577, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI115533556, Length=350, Percent_Identity=28.2857142857143, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI115533554, Length=351, Percent_Identity=27.9202279202279, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17554148, Length=329, Percent_Identity=25.8358662613982, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17535049, Length=428, Percent_Identity=23.8317757009346, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17554962, Length=329, Percent_Identity=25.531914893617, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71997452, Length=397, Percent_Identity=22.6700251889169, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193205400, Length=338, Percent_Identity=23.3727810650888, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI32565914, Length=344, Percent_Identity=22.6744186046512, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17552542, Length=420, Percent_Identity=21.4285714285714, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI32565916, Length=239, Percent_Identity=24.6861924686192, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25141316, Length=372, Percent_Identity=22.3118279569892, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI25141318, Length=372, Percent_Identity=22.3118279569892, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71991448, Length=385, Percent_Identity=21.8181818181818, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25141341, Length=366, Percent_Identity=21.5846994535519, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71991453, Length=385, Percent_Identity=21.8181818181818, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI86561091, Length=276, Percent_Identity=23.9130434782609, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17563054, Length=352, Percent_Identity=23.0113636363636, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17532009, Length=241, Percent_Identity=22.8215767634855, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17537329, Length=321, Percent_Identity=24.2990654205607, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561498, Length=209, Percent_Identity=29.1866028708134, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536545, Length=417, Percent_Identity=24.9400479616307, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI115534558, Length=206, Percent_Identity=28.1553398058252, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17560030, Length=216, Percent_Identity=21.7592592592593, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71983953, Length=321, Percent_Identity=22.1183800623053, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17566884, Length=294, Percent_Identity=21.4285714285714, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560966, Length=226, Percent_Identity=23.4513274336283, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562692, Length=322, Percent_Identity=22.0496894409938, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI32566049, Length=409, Percent_Identity=20.7823960880196, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI19922400, Length=363, Percent_Identity=28.9256198347107, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24583789, Length=362, Percent_Identity=25.1381215469613, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24654215, Length=363, Percent_Identity=28.9256198347107, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI28573708, Length=427, Percent_Identity=25.0585480093677, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28573707, Length=427, Percent_Identity=25.0585480093677, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI19920686, Length=386, Percent_Identity=26.9430051813472, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24584153, Length=381, Percent_Identity=23.8845144356955, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24655271, Length=415, Percent_Identity=26.2650602409639, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI20130135, Length=415, Percent_Identity=26.5060240963855, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24639764, Length=385, Percent_Identity=26.4935064935065, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI20130167, Length=416, Percent_Identity=23.7980769230769, Blast_Score=111, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24648416, Length=418, Percent_Identity=25.5980861244019, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21356189, Length=418, Percent_Identity=25.5980861244019, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24580790, Length=365, Percent_Identity=24.1095890410959, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI45550460, Length=418, Percent_Identity=24.8803827751196, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24641682, Length=373, Percent_Identity=25.4691689008043, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24655255, Length=384, Percent_Identity=24.21875, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI28573299, Length=390, Percent_Identity=25.3846153846154, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45552797, Length=411, Percent_Identity=22.6277372262774, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24658689, Length=411, Percent_Identity=22.6277372262774, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI62484226, Length=355, Percent_Identity=23.943661971831, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI20129235, Length=342, Percent_Identity=24.5614035087719, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI45550364, Length=423, Percent_Identity=23.6406619385343, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24651789, Length=368, Percent_Identity=24.7282608695652, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24651787, Length=368, Percent_Identity=24.7282608695652, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24658666, Length=443, Percent_Identity=22.7990970654628, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24658658, Length=431, Percent_Identity=22.2737819025522, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24653727, Length=377, Percent_Identity=24.6684350132626, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221474708, Length=369, Percent_Identity=20.8672086720867, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281361682, Length=409, Percent_Identity=20.0488997555012, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47616; Mature: 47616

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCC
>Mature Secondary Structure
MKEKRTNVRWMFALAFFFIGVIAYMDRANISYIAKQMMDDLGMTKPQFGLLASFFSLGYA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LMQVPSGMLAEKFGPRKMITIALVWWSAFTILTGMIKNHGLIYLVRFLFGVGEAPMYPSN
HHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCH
AVFNSFWFSKNEKGRASSALLAGSYFGPVLAPIVTIAIVNAFNWQAVFYIFGAVGILMAV
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LWAIIAKDLSEQHRMVNEAEKRFIMENRDIVATEKSSPPWNNFFKRFSFYAIAIQYFVVQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
FIITLFLIWLPTYLTEVFHVNFKEMSISSLPWLLMFFLILSAGAISDRVLGLGRSKFVAR
HHHHHHHHHHHHHHHHHHHCCHHHHCHHCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHH
GVIAIAGFIVFAVSIIFAVRTGNLYVSIFWLSLGLGGIGISMGMSWAAATDLGRNFSGTV
HHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHCCCHHHHHHCCHHHHHHHCCCCCCHHH
SGWMNLWGNIGALISPLLAGLFVEHLGWTMTFQLLIVPAVIAVIMWFYVKPDQPLIVSDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCC
KAIEK
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]