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The map label for this gene is sarT [H]

Identifier: 148268932

GI number: 148268932

Start: 2664423

End: 2664779

Strand: Reverse

Name: sarT [H]

Synonym: SaurJH9_2522

Alternate gene names: 148268932

Gene position: 2664779-2664423 (Counterclockwise)

Preceding gene: 148268934

Following gene: 148268931

Centisome position: 91.68

GC content: 22.69

Gene sequence:

>357_bases
ATGAATGATTTGAAAAGCAAGAGCAATATTAAATTAATGAAAAGAGTATTAACTACATATGAGCTGCGTAAATATTTAAA
AAAATATTTTTGTCTTACATTAGATAATTATTTAGTATTAGCATATTTAGATGTATTTAAAAATGATGAAGGTAAATATT
TTATGAGAGACATTATAAGTTATATCGGTATAGACCAATCTAGAATTGTTAAAAGCGTAAAAGAATTATCAAAAAAGGGT
TACTTGAATAAATGTAGAGACCCACATGATAGTAGAAATGTAATCATTGTTGTTTCTGTAAAACAACACAATTATATTAA
AAATCTTTTGAGTGAAATAAATATTAATGAAACATAA

Upstream 100 bases:

>100_bases
GTTTATAGCTAGCACCACAAACTAAATATATTTGGAGTTATTACTAGTTAAAGACAAATATTATTTGACGTGACAATTAA
AAGTAAGGGATGAAGACTTG

Downstream 100 bases:

>100_bases
AGTATGTTTCGAGATTTTAATATCTTGGTGCAGTTAAATGTATTTTTAAATGCGTTAAGGTATTTTTTATTTTAGAAATT
CAATGCTATTGAGTTGATGG

Product: SarA family transcriptional regulator

Products: NA

Alternate protein names: Staphylococcal accessory regulator T [H]

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIISYIGIDQSRIVKSVKELSKKG
YLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET

Sequences:

>Translated_118_residues
MNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIISYIGIDQSRIVKSVKELSKKG
YLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET
>Mature_118_residues
MNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIISYIGIDQSRIVKSVKELSKKG
YLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET

Specific function: Transcriptional regulator acting as an intermediary between major regulators sarA and agr and virulence genes. Represses alpha-hemolysin (hla) gene expression. Down-regulates agr RNAIII expression by repressing sarU, a positive activator of agr expression

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sarA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010166
- InterPro:   IPR011991 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 14003; Mature: 14003

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIIS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
YIGIDQSRIVKSVKELSKKGYLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET
HHCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEEEECHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIIS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
YIGIDQSRIVKSVKELSKKGYLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET
HHCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEEEECHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12496184 [H]