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The map label for this gene is dinB [H]

Identifier: 148268367

GI number: 148268367

Start: 2080550

End: 2081620

Strand: Reverse

Name: dinB [H]

Synonym: SaurJH9_1949

Alternate gene names: 148268367

Gene position: 2081620-2080550 (Counterclockwise)

Preceding gene: 148268368

Following gene: 148268364

Centisome position: 71.61

GC content: 34.45

Gene sequence:

>1071_bases
TTGACTGAGAGACGAATTATTCATATAGATATGGACTATTTTTTTGCACAAGTCGAAATGAGAGATAACCCCAAATTGAA
AGGGAAACCAGTCATTGTTGGTGGTAAAGCAAGCAGTAGGGGTGTTGTCTCTACGGCATCCTATGAAGCACGAAAATACG
GCGTCCATTCAGCAATGCCTATGTCACAAGCGCATAAATTATGTCCAAATGGATACTTTGTCACAAGTAATTTTGGTGCT
TACCGAGAAACATCTGCGCAGATTATGTCTATTTTCCGAAGTTATACAGATAAGGTAGAACCGATGTCATTGGATGAAGC
GTATTTAGATATTACAGAATTAGTGAGACCAGACCTTCCTGCTTCGAAAATTGCTCAGTATATTAGAAAAGATATTCTAG
AGCAGACACATTTAACAGCATCTGCAGGTGTTTCTTATAACAAATTTTTAGCTAAATTAGCGAGTGGTATGAATAAACCT
GATGGTTTGACTGTGATTGATTATCAAAATGTCCATGATATTTTGATGACATTGGATATTGGAGATTTTCCAGGCGTAGG
TAAAGCTTCCAAAAAAGTAATGCATGATAATGGTATTTTTAACGGTAGAGATTTATATGAGAAAACGGAATTTGAATTAA
TACGTTTGTTTGGAAAAAGAGGTCGGGGTTTATATAACAAGGCACGCGGTATTGACCATAGTGAAGTGAAATCATCAAGA
GTAAGAAAATCAGTAGGGACTGAACGCACATTTGCAACAGACGTGAATGATGATGAAGAGATTTTAAGAAAAGTATGGGA
ATTGTCAGGTAAAACAGCTGAACGTCTAAATAAATTACAGAAGTCAGCTAAAACTGTAACGGTTAAAATTAAAACTTATC
AATTTGAAACGCTATCTAAACAGATGAGTTTAAGAGATTCGGTTAGTTCTGAAGAAGATATTTATAATATTGCATATTTA
CTTTATAACGATTTAAAAGACCCAGATGTACCAATTCGACTTATTGGTGTCACTGTAGGTAATTTAGAACAATCAACTAA
TAAAAATATGACGATATATGACTTTATATAA

Upstream 100 bases:

>100_bases
CTAAGTGCAAGATTTATGTAAAAAAATCGTACACAGCGTATAATTATGTTGAGATATTTTTGTGCGTTATAAAAGTAAAA
ATTAGTAGGGAGGTGAGCAC

Downstream 100 bases:

>100_bases
AATAAAGCTCCCTGCAAAGTTTACATTTTTACAATGCTTACTTTTGAAGGGAGTATTTTATTTAGTCCTAGCCTTTATCT
TTTAGATTTTTACCATAAAT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGA
YRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKP
DGLTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSR
VRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYL
LYNDLKDPDVPIRLIGVTVGNLEQSTNKNMTIYDFI

Sequences:

>Translated_356_residues
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGA
YRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKP
DGLTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSR
VRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYL
LYNDLKDPDVPIRLIGVTVGNLEQSTNKNMTIYDFI
>Mature_355_residues
TERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAY
RETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPD
GLTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRV
RKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLL
YNDLKDPDVPIRLIGVTVGNLEQSTNKNMTIYDFI

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7706681, Length=339, Percent_Identity=30.9734513274336, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI84043967, Length=338, Percent_Identity=31.0650887573964, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI5729982, Length=349, Percent_Identity=29.7994269340974, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI154350220, Length=332, Percent_Identity=29.8192771084337, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI7705344, Length=126, Percent_Identity=46.031746031746, Blast_Score=112, Evalue=4e-25,
Organism=Escherichia coli, GI1786425, Length=298, Percent_Identity=45.9731543624161, Blast_Score=251, Evalue=3e-68,
Organism=Escherichia coli, GI1787432, Length=298, Percent_Identity=26.8456375838926, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193205700, Length=419, Percent_Identity=29.3556085918854, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17537959, Length=377, Percent_Identity=27.5862068965517, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI115534089, Length=393, Percent_Identity=26.7175572519084, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI193205702, Length=364, Percent_Identity=26.6483516483516, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324921, Length=206, Percent_Identity=30.0970873786408, Blast_Score=76, Evalue=6e-15,
Organism=Drosophila melanogaster, GI19923006, Length=412, Percent_Identity=26.6990291262136, Blast_Score=148, Evalue=5e-36,
Organism=Drosophila melanogaster, GI21355641, Length=285, Percent_Identity=29.4736842105263, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24644984, Length=285, Percent_Identity=29.4736842105263, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24668444, Length=356, Percent_Identity=26.123595505618, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 40248; Mature: 40117

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMP
CCCCEEEEEEHHHEEEEEEECCCCCCCCCCEEEECCCCCCCCEEECCHHHHHHCCCCCCC
MSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLP
HHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
ASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGLTVIDYQNVHDILMTLDI
HHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEC
GDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSR
CCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHH
VRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSK
HHHHHCCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEEEEHHHHHH
QMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTNKNMTIYDFI
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHCCCCCEEEEECC
>Mature Secondary Structure 
TERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMP
CCCEEEEEEHHHEEEEEEECCCCCCCCCCEEEECCCCCCCCEEECCHHHHHHCCCCCCC
MSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLP
HHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
ASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGLTVIDYQNVHDILMTLDI
HHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEC
GDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSR
CCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHH
VRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSK
HHHHHCCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEEEEHHHHHH
QMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTNKNMTIYDFI
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA