Click here to switch to the map view.

The map label for this gene is ymfI [H]

Identifier: 148267770

GI number: 148267770

Start: 1400951

End: 1401655

Strand: Direct

Name: ymfI [H]

Synonym: SaurJH9_1340

Alternate gene names: 148267770

Gene position: 1400951-1401655 (Clockwise)

Preceding gene: 148267769

Following gene: 148267771

Centisome position: 48.2

GC content: 34.04

Gene sequence:

>705_bases
ATGAAAGCATTAGTATTAGGTGGTTCTGGTTCAATTGGTTCTGAGATAGTCAAACAATTATTAACTGATGGATTTGAAGT
TTATGTGCAATATTATCGTACTGATATAAATGAATTAACTAGCAAATTTAATGATGATAAAGTTCGTTTTATACAAGCGG
ATTTATCTCAAACAATTGATATTGACAAAACATTTGGTGACATTAAATCATTAGACTGTTTAATATATGCAAGTGGTCAG
TCTTTATATGGTGTTTTACAAGATATGAAAGACCATGATATTGATGCATGTTATCAGTTAAATGTCTTGCAATTAATTCG
ATTATGTAGATATTTCGTTGATGTTTTACGTCAAAGTGCCAATGGAAGAATTATTGTAATTTCATCAATTTGGGGTGAGA
CAGGAGCTAGTATGGAAACTATTTATTCGGCGATGAAAAGTGCACAATTAGGTTTCGTTAAGGCGCTTAGTCAAGAGCTT
GCACTAACATCAGTGACAGTAAATGCTATCGCACCTGGATTTGTAGCCGGTAATATGGCAAGTGAGTGGCAAGAAGATGA
ACTTCAAGCAATGATAACTGAATTACCACAACAGCGATTGGTTTTACCGAGTGAGGTTGCTCATACATGCGCCTATTTAT
ATCACTCAAATGCTAGAAGCGTTACTGGAACTATACAGAAAGTTAATGGTGCTTGGTATATTTAA

Upstream 100 bases:

>100_bases
ACATTGTTGAAAATATCACGTTAGATAGTATTAACGAAACGTCATCGTTATATTTAAATTTAGATCAGCAAGTCGATAGT
CGTTTGGAGATTAAAAAGTA

Downstream 100 bases:

>100_bases
AATATAGAACTATTTTTATGAGCAAATGTTTTTATGATTGATGTTATAATATGAATATTACAATGAATCATAATTTGTTA
ATTAAACAAGGGGTGAGGTT

Product: short-chain dehydrogenase/reductase SDR

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MKALVLGGSGSIGSEIVKQLLTDGFEVYVQYYRTDINELTSKFNDDKVRFIQADLSQTIDIDKTFGDIKSLDCLIYASGQ
SLYGVLQDMKDHDIDACYQLNVLQLIRLCRYFVDVLRQSANGRIIVISSIWGETGASMETIYSAMKSAQLGFVKALSQEL
ALTSVTVNAIAPGFVAGNMASEWQEDELQAMITELPQQRLVLPSEVAHTCAYLYHSNARSVTGTIQKVNGAWYI

Sequences:

>Translated_234_residues
MKALVLGGSGSIGSEIVKQLLTDGFEVYVQYYRTDINELTSKFNDDKVRFIQADLSQTIDIDKTFGDIKSLDCLIYASGQ
SLYGVLQDMKDHDIDACYQLNVLQLIRLCRYFVDVLRQSANGRIIVISSIWGETGASMETIYSAMKSAQLGFVKALSQEL
ALTSVTVNAIAPGFVAGNMASEWQEDELQAMITELPQQRLVLPSEVAHTCAYLYHSNARSVTGTIQKVNGAWYI
>Mature_234_residues
MKALVLGGSGSIGSEIVKQLLTDGFEVYVQYYRTDINELTSKFNDDKVRFIQADLSQTIDIDKTFGDIKSLDCLIYASGQ
SLYGVLQDMKDHDIDACYQLNVLQLIRLCRYFVDVLRQSANGRIIVISSIWGETGASMETIYSAMKSAQLGFVKALSQEL
ALTSVTVNAIAPGFVAGNMASEWQEDELQAMITELPQQRLVLPSEVAHTCAYLYHSNARSVTGTIQKVNGAWYI

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=235, Percent_Identity=27.6595744680851, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI66933014, Length=216, Percent_Identity=26.3888888888889, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=236, Percent_Identity=27.1186440677966, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI2367365, Length=236, Percent_Identity=29.2372881355932, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082100, Length=243, Percent_Identity=26.3374485596708, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1789208, Length=178, Percent_Identity=25.8426966292135, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082160, Length=240, Percent_Identity=22.5, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789057, Length=217, Percent_Identity=23.963133640553, Blast_Score=62, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=241, Percent_Identity=27.3858921161826, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=238, Percent_Identity=27.7310924369748, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=27.5720164609054, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=244, Percent_Identity=26.2295081967213, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=205, Percent_Identity=30.2439024390244, Blast_Score=76, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24643142, Length=222, Percent_Identity=24.3243243243243, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355319, Length=235, Percent_Identity=27.2340425531915, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI23397609, Length=239, Percent_Identity=25.9414225941423, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 25915; Mature: 25915

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALVLGGSGSIGSEIVKQLLTDGFEVYVQYYRTDINELTSKFNDDKVRFIQADLSQTID
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHHHHCC
IDKTFGDIKSLDCLIYASGQSLYGVLQDMKDHDIDACYQLNVLQLIRLCRYFVDVLRQSA
CHHHHHHHHHCEEEEEECCHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCC
NGRIIVISSIWGETGASMETIYSAMKSAQLGFVKALSQELALTSVTVNAIAPGFVAGNMA
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHCCCHHCCCHH
SEWQEDELQAMITELPQQRLVLPSEVAHTCAYLYHSNARSVTGTIQKVNGAWYI
HHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCHHHHHHEECCCCCCC
>Mature Secondary Structure
MKALVLGGSGSIGSEIVKQLLTDGFEVYVQYYRTDINELTSKFNDDKVRFIQADLSQTID
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHHHHCC
IDKTFGDIKSLDCLIYASGQSLYGVLQDMKDHDIDACYQLNVLQLIRLCRYFVDVLRQSA
CHHHHHHHHHCEEEEEECCHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCC
NGRIIVISSIWGETGASMETIYSAMKSAQLGFVKALSQELALTSVTVNAIAPGFVAGNMA
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHCCCHHCCCHH
SEWQEDELQAMITELPQQRLVLPSEVAHTCAYLYHSNARSVTGTIQKVNGAWYI
HHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCHHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]