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The map label for this gene is purN [H]

Identifier: 148267565

GI number: 148267565

Start: 1174152

End: 1174718

Strand: Direct

Name: purN [H]

Synonym: SaurJH9_1132

Alternate gene names: 148267565

Gene position: 1174152-1174718 (Clockwise)

Preceding gene: 148267564

Following gene: 148267566

Centisome position: 40.39

GC content: 32.1

Gene sequence:

>567_bases
ATGGTTAAAATTGCGATTTTTGCATCAGGTTCAGGAAGTAACTTTGAAAATATAGTTGAGCATGTTGAATCAGGAAAACT
TGAAAATATTGAAGTTACGGCGCTATATACGGATCATCAAAATGCGTTTTGTATAGATAGAGCAAAAAAGCACGATATTC
CTGTTTATATTAATGAACCAAAACAATTTGATTCAAAAGCAGCGTATGAACAACATTTAGTAACATTATTAAATAAAGAT
AAGGTAGAGTGGATTATTTTAGCTGGCTACATGCGTCTAATTGGTCCAGATTTATTAGCTTCATTTGAAGGTAAAATATT
GAATATACATCCATCTCTATTGCCGAAATATAAGGGGATTGACGCAATAGGCCAAGCATATCATAGTGGCGATACTATTA
CTGGTTCGACAGTACATTATGTTGATTGTGGTATGGATACGGGAGAAATTATTGAACAGAGACAATGTGATATTAGACCG
GACGATTCAAAAGAACAATTAGAAGAGAAAGTAAAAAAATTGGAATATGAGTTATATCCAAGTGTTATTGCTAAAATTGT
AAAATAA

Upstream 100 bases:

>100_bases
GCGCTTTGAAGATTTTAGCAGAACAAAATGTGGAAGCTTATCAAATTGGTCATATTGTGAAAAATGAGTCAACTGCAATT
GAATTGTTGGGGGTATAACA

Downstream 100 bases:

>100_bases
GGAGTATGTATGTGATGAAGAAAGCTATTTTGAGCGTATCAAATAAAACAGGTATTGTAGAGTTTGCTAAAGCGTTAACG
CAATTAAATTATGAATTATA

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVTLLNKD
KVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDCGMDTGEIIEQRQCDIRP
DDSKEQLEEKVKKLEYELYPSVIAKIVK

Sequences:

>Translated_188_residues
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVTLLNKD
KVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDCGMDTGEIIEQRQCDIRP
DDSKEQLEEKVKKLEYELYPSVIAKIVK
>Mature_188_residues
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVTLLNKD
KVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDCGMDTGEIIEQRQCDIRP
DDSKEQLEEKVKKLEYELYPSVIAKIVK

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=181, Percent_Identity=29.2817679558011, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI209869995, Length=181, Percent_Identity=29.2817679558011, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI209869993, Length=181, Percent_Identity=29.2817679558011, Blast_Score=112, Evalue=2e-25,
Organism=Escherichia coli, GI1788846, Length=183, Percent_Identity=32.7868852459016, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787483, Length=151, Percent_Identity=28.476821192053, Blast_Score=75, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17567511, Length=191, Percent_Identity=32.4607329842932, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320616, Length=198, Percent_Identity=25.7575757575758, Blast_Score=72, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24582400, Length=186, Percent_Identity=33.8709677419355, Blast_Score=128, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 21166; Mature: 21166

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEP
CEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCEEEECCCCCCCCCEEECCC
KQFDSKAAYEQHLVTLLNKDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGI
HHCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHCHHHHHHCCCCEEEECHHHCCCCCCH
DAIGQAYHSGDTITGSTVHYVDCGMDTGEIIEQRQCDIRPDDSKEQLEEKVKKLEYELYP
HHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
SVIAKIVK
HHHHHHCC
>Mature Secondary Structure
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEP
CEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCEEEECCCCCCCCCEEECCC
KQFDSKAAYEQHLVTLLNKDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGI
HHCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHCHHHHHHCCCCEEEECHHHCCCCCCH
DAIGQAYHSGDTITGSTVHYVDCGMDTGEIIEQRQCDIRPDDSKEQLEEKVKKLEYELYP
HHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
SVIAKIVK
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA