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The map label for this gene is purE [H]

Identifier: 148267557

GI number: 148267557

Start: 1166246

End: 1166728

Strand: Direct

Name: purE [H]

Synonym: SaurJH9_1124

Alternate gene names: 148267557

Gene position: 1166246-1166728 (Clockwise)

Preceding gene: 148267554

Following gene: 148267558

Centisome position: 40.12

GC content: 38.1

Gene sequence:

>483_bases
GTGAAAGTAGCAGTCATTATGGGCAGTTCTTCCGATTGGAAAATTATGCAAGAGAGTTGTAACATGTTGGATTATTTTGA
AATTCCGTACGAAAAACAAGTAGTATCCGCACATCGTACGCCAAAAATGATGGTTCAATTTGCTTCTGAAGCGAGAGAAA
GAGGTATAAACATTATCATTGCAGGCGCTGGCGGTGCGGCACATTTACCAGGTATGGTTGCATCATTAACGACGCTACCA
GTTATTGGTGTGCCGATTGAAACAAAAAGTTTAAAGAGTATAGATTCTTTATTATCAATTGTTCAAATGCCAGGAGGTAT
TCCGGTTGCAACGACTGCAATTGGTGCAGCAGGTGCTAAAAACGCAGGTATACTTGCAGCAAGAATGTTAAGTATTCAAA
ATCCTTCTTTAGTTGAAAAACTAAATCAGTATGAATCTTCGTTAATTCAAAAAGTGGAGGACATGCAAAATGAACTTCAA
TAA

Upstream 100 bases:

>100_bases
TTCGATTTTTGATTGAAAAAGCAGAAATTGCTTGTTATGCTATATCTATAATATACAACTAAAGTAATTCACAATTCAAA
CTTTTGAAAGGGTGTACAAA

Downstream 100 bases:

>100_bases
ATTAAAGTTTGGTGCGACTATTGGCATTATTGGTGGTGGTCAGCTTGGAAAGATGATGGCACAATCAGCTCAAAAAATGG
GTTATAAAGTGGTTGTATTG

Product: phosphoribosylaminoimidazole carboxylase, catalytic subunit

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKVAVIMGSSSDWKIMQESCNMLDYFEIPYEKQVVSAHRTPKMMVQFASEARERGINIIIAGAGGAAHLPGMVASLTTLP
VIGVPIETKSLKSIDSLLSIVQMPGGIPVATTAIGAAGAKNAGILAARMLSIQNPSLVEKLNQYESSLIQKVEDMQNELQ

Sequences:

>Translated_160_residues
MKVAVIMGSSSDWKIMQESCNMLDYFEIPYEKQVVSAHRTPKMMVQFASEARERGINIIIAGAGGAAHLPGMVASLTTLP
VIGVPIETKSLKSIDSLLSIVQMPGGIPVATTAIGAAGAKNAGILAARMLSIQNPSLVEKLNQYESSLIQKVEDMQNELQ
>Mature_160_residues
MKVAVIMGSSSDWKIMQESCNMLDYFEIPYEKQVVSAHRTPKMMVQFASEARERGINIIIAGAGGAAHLPGMVASLTTLP
VIGVPIETKSLKSIDSLLSIVQMPGGIPVATTAIGAAGAKNAGILAARMLSIQNPSLVEKLNQYESSLIQKVEDMQNELQ

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=151, Percent_Identity=50.3311258278146, Blast_Score=137, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6324702, Length=142, Percent_Identity=53.5211267605634, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 17099; Mature: 17099

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAVIMGSSSDWKIMQESCNMLDYFEIPYEKQVVSAHRTPKMMVQFASEARERGINIII
CEEEEEECCCCCHHHHHHHCCEEEHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEE
AGAGGAAHLPGMVASLTTLPVIGVPIETKSLKSIDSLLSIVQMPGGIPVATTAIGAAGAK
ECCCCCHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCC
NAGILAARMLSIQNPSLVEKLNQYESSLIQKVEDMQNELQ
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVAVIMGSSSDWKIMQESCNMLDYFEIPYEKQVVSAHRTPKMMVQFASEARERGINIII
CEEEEEECCCCCHHHHHHHCCEEEHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEE
AGAGGAAHLPGMVASLTTLPVIGVPIETKSLKSIDSLLSIVQMPGGIPVATTAIGAAGAK
ECCCCCHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCC
NAGILAARMLSIQNPSLVEKLNQYESSLIQKVEDMQNELQ
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3036807; 9384377 [H]