The gene/protein map for NC_009487 is currently unavailable.
Definition Staphylococcus aureus subsp. aureus JH9, complete genome.
Accession NC_009487
Length 2,906,700

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The map label for this gene is ppiB [C]

Identifier: 148267388

GI number: 148267388

Start: 997656

End: 998249

Strand: Direct

Name: ppiB [C]

Synonym: SaurJH9_0954

Alternate gene names: 148267388

Gene position: 997656-998249 (Clockwise)

Preceding gene: 148267378

Following gene: 148267389

Centisome position: 34.32

GC content: 35.19

Gene sequence:

>594_bases
ATGGCTAACTATCCACAGTTAAACAAAGAAGTACAACAAGGTGAAATTAAAGTGGTTATGCACACAAATAAAGGTGACAT
GACATTCAAATTATTTCCAAATATTGCACCAAAAACAGTTGAAAATTTTGTGACACATGCAAAAAATGGTTATTATGATG
GAATAACATTCCACCGTGTCATTAATGACTTCATGATTCAAGGTGGCGATCCAACAGCTACTGGTATGGGTGGCGAAAGT
ATTTATGGCGGTGCTTTTGAAGATGAATTTTCATTAAATGCATTTAACTTATATGGCGCATTATCAATGGCTAACTCAGG
ACCTAATACTAATGGTTCACAATTTTTCATTGTTCAAATGAAAGAAGTACCTCAAAATATGTTAAGTCAACTTGCAGATG
GTGGCTGGCCTCAACCAATCGTTGATGCATATGGCGAAAAGGGTGGTACACCATGGTTAGATCAAAAACATACAGTATTC
GGTCAAATCATTGATGGTGAAACTACTTTAGAAGATATTGCAAATACAAAAGTGGGACCACAAGACAAACCACTTCATGA
TGTTGTAATTGAATCTATTGATGTTGAAGAATAA

Upstream 100 bases:

>100_bases
AGCTACCTGTTTTGTGTGAAAATCGATATAGCTTCATGCTATTTTCCTCCCTTAAAAGTATGTTAATATATATGTATCAT
AACATGAATGGAGAATATAA

Downstream 100 bases:

>100_bases
TAGCTAAACATAATTAACTACCAACATTTTAAACTCGGATAAAGCTAATTTATGAATGGATTAGTATATATTCCAACGAA
ACAAATAAACTAACATGATG

Product: peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase; Rotamase

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGES
IYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVF
GQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE

Sequences:

>Translated_197_residues
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGES
IYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVF
GQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>Mature_196_residues
ANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESI
YGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFG
QIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain

Homologues:

Organism=Homo sapiens, GI24308049, Length=181, Percent_Identity=51.3812154696133, Blast_Score=166, Evalue=1e-41,
Organism=Homo sapiens, GI19557636, Length=183, Percent_Identity=42.0765027322404, Blast_Score=136, Evalue=1e-32,
Organism=Homo sapiens, GI7706339, Length=174, Percent_Identity=42.5287356321839, Blast_Score=132, Evalue=1e-31,
Organism=Homo sapiens, GI4758950, Length=181, Percent_Identity=42.5414364640884, Blast_Score=117, Evalue=6e-27,
Organism=Homo sapiens, GI22547212, Length=180, Percent_Identity=41.1111111111111, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI7657473, Length=180, Percent_Identity=41.1111111111111, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI22547215, Length=180, Percent_Identity=41.1111111111111, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI4505991, Length=171, Percent_Identity=43.859649122807, Blast_Score=114, Evalue=6e-26,
Organism=Homo sapiens, GI5454154, Length=176, Percent_Identity=42.6136363636364, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI64276486, Length=182, Percent_Identity=35.7142857142857, Blast_Score=111, Evalue=3e-25,
Organism=Homo sapiens, GI42560244, Length=180, Percent_Identity=39.4444444444444, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI6631100, Length=178, Percent_Identity=38.7640449438202, Blast_Score=104, Evalue=4e-23,
Organism=Homo sapiens, GI4826932, Length=185, Percent_Identity=38.3783783783784, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI10863927, Length=151, Percent_Identity=42.3841059602649, Blast_Score=101, Evalue=3e-22,
Organism=Homo sapiens, GI5174637, Length=171, Percent_Identity=39.766081871345, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI5031987, Length=154, Percent_Identity=42.2077922077922, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI303305009, Length=163, Percent_Identity=39.8773006134969, Blast_Score=97, Evalue=8e-21,
Organism=Homo sapiens, GI45439316, Length=153, Percent_Identity=40.5228758169935, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI256017253, Length=143, Percent_Identity=41.958041958042, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI221139811, Length=143, Percent_Identity=41.958041958042, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI256017251, Length=143, Percent_Identity=41.958041958042, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI310129267, Length=153, Percent_Identity=40.5228758169935, Blast_Score=94, Evalue=6e-20,
Organism=Homo sapiens, GI310120620, Length=153, Percent_Identity=40.5228758169935, Blast_Score=94, Evalue=6e-20,
Organism=Homo sapiens, GI209417936, Length=143, Percent_Identity=41.2587412587413, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI30102944, Length=143, Percent_Identity=41.2587412587413, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI219842199, Length=143, Percent_Identity=41.2587412587413, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI178057341, Length=143, Percent_Identity=41.2587412587413, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI310110104, Length=153, Percent_Identity=39.8692810457516, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI310127646, Length=151, Percent_Identity=37.7483443708609, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI310114371, Length=151, Percent_Identity=37.7483443708609, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI310119221, Length=151, Percent_Identity=37.7483443708609, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI169163387, Length=153, Percent_Identity=37.9084967320261, Blast_Score=87, Evalue=7e-18,
Organism=Homo sapiens, GI150418007, Length=153, Percent_Identity=40.5228758169935, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI14277126, Length=186, Percent_Identity=34.9462365591398, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI169164185, Length=151, Percent_Identity=37.7483443708609, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI169163623, Length=151, Percent_Identity=37.7483443708609, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI20911035, Length=181, Percent_Identity=31.4917127071823, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI27735045, Length=177, Percent_Identity=32.2033898305085, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI310132444, Length=153, Percent_Identity=37.2549019607843, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI310113152, Length=153, Percent_Identity=37.2549019607843, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI169214050, Length=162, Percent_Identity=35.1851851851852, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI239751853, Length=162, Percent_Identity=35.1851851851852, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI113428306, Length=162, Percent_Identity=35.1851851851852, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI310114540, Length=153, Percent_Identity=35.2941176470588, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI310127745, Length=153, Percent_Identity=35.2941176470588, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI310119290, Length=153, Percent_Identity=35.2941176470588, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI1786736, Length=189, Percent_Identity=32.8042328042328, Blast_Score=82, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71980594, Length=181, Percent_Identity=40.3314917127072, Blast_Score=133, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI71980590, Length=171, Percent_Identity=42.1052631578947, Blast_Score=132, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17532641, Length=194, Percent_Identity=40.2061855670103, Blast_Score=128, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17506311, Length=193, Percent_Identity=40.4145077720207, Blast_Score=124, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17539496, Length=174, Percent_Identity=39.6551724137931, Blast_Score=121, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17552780, Length=171, Percent_Identity=43.859649122807, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17506307, Length=173, Percent_Identity=42.1965317919075, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71997782, Length=148, Percent_Identity=39.8648648648649, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17551282, Length=177, Percent_Identity=41.2429378531073, Blast_Score=107, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17551284, Length=177, Percent_Identity=41.2429378531073, Blast_Score=107, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17565860, Length=164, Percent_Identity=40.8536585365854, Blast_Score=103, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17532643, Length=176, Percent_Identity=38.0681818181818, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17559074, Length=178, Percent_Identity=37.0786516853933, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17566266, Length=153, Percent_Identity=40.5228758169935, Blast_Score=98, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17539498, Length=177, Percent_Identity=36.7231638418079, Blast_Score=98, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17552784, Length=182, Percent_Identity=35.1648351648352, Blast_Score=94, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17552782, Length=160, Percent_Identity=37.5, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI32563659, Length=181, Percent_Identity=31.4917127071823, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323562, Length=174, Percent_Identity=41.9540229885057, Blast_Score=115, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6320359, Length=153, Percent_Identity=45.7516339869281, Blast_Score=112, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6321848, Length=187, Percent_Identity=39.0374331550802, Blast_Score=109, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320510, Length=185, Percent_Identity=39.4594594594595, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323246, Length=186, Percent_Identity=38.7096774193548, Blast_Score=101, Evalue=9e-23,
Organism=Drosophila melanogaster, GI19922376, Length=179, Percent_Identity=41.8994413407821, Blast_Score=148, Evalue=3e-36,
Organism=Drosophila melanogaster, GI19922912, Length=188, Percent_Identity=47.8723404255319, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI17986117, Length=181, Percent_Identity=39.2265193370166, Blast_Score=128, Evalue=3e-30,
Organism=Drosophila melanogaster, GI20130249, Length=171, Percent_Identity=42.1052631578947, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24650807, Length=178, Percent_Identity=39.3258426966292, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24652460, Length=184, Percent_Identity=35.3260869565217, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI17647301, Length=175, Percent_Identity=40.5714285714286, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24586038, Length=208, Percent_Identity=35.5769230769231, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21357249, Length=182, Percent_Identity=35.7142857142857, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI17136360, Length=184, Percent_Identity=37.5, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24664125, Length=175, Percent_Identity=40, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357783, Length=175, Percent_Identity=40, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45549139, Length=154, Percent_Identity=41.5584415584416, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21355677, Length=191, Percent_Identity=30.3664921465969, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24661775, Length=105, Percent_Identity=41.9047619047619, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21355237, Length=105, Percent_Identity=41.9047619047619, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24661771, Length=105, Percent_Identity=41.9047619047619, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: 780 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): PPI1_STAA3 (Q2FIC1)

Other databases:

- EMBL:   CP000255
- RefSeq:   YP_493557.1
- HSSP:   Q4DPB9
- ProteinModelPortal:   Q2FIC1
- SMR:   Q2FIC1
- STRING:   Q2FIC1
- EnsemblBacteria:   EBSTAT00000038723
- GeneID:   3915127
- GenomeReviews:   CP000255_GR
- KEGG:   saa:SAUSA300_0857
- eggNOG:   COG0652
- GeneTree:   EBGT00050000024926
- HOGENOM:   HBG610621
- OMA:   FSATSHI
- ProtClustDB:   CLSK876800
- InterPro:   IPR015891
- InterPro:   IPR002130
- Gene3D:   G3DSA:2.40.100.10
- PRINTS:   PR00153

Pfam domain/function: PF00160 Pro_isomerase; SSF50891 CSA_PPIase

EC number: =5.2.1.8

Molecular weight: Translated: 21619; Mature: 21488

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS00170 CSA_PPIASE_1; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRV
CCCCCCCHHHHHCCCEEEEEECCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHH
INDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQM
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHEECCCCCCCCCCCEEEEEEH
KEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGP
HHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCCC
QDKPLHDVVIESIDVEE
CCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
ANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRV
CCCCCCHHHHHCCCEEEEEECCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHH
INDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQM
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHEECCCCCCCCCCCEEEEEEH
KEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGP
HHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCCC
QDKPLHDVVIESIDVEE
CCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA