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The map label for this gene is phr [H]

Identifier: 148267151

GI number: 148267151

Start: 782315

End: 783688

Strand: Direct

Name: phr [H]

Synonym: SaurJH9_0715

Alternate gene names: 148267151

Gene position: 782315-783688 (Clockwise)

Preceding gene: 148267150

Following gene: 148267155

Centisome position: 26.91

GC content: 34.06

Gene sequence:

>1374_bases
ATGGCAATTGCTGTGTTATTAAATCGAATGTTTCGAATGGAACACAATCCATTATTTGAATATATTTATCAACAAAAAGA
AGACATTGATGCATGTTATTTTATCATTCCGGAAGAGGACATGTCTTCAGCTTCTGATTTGAAAGCACAGTTTTATCGCG
GTACTTTGCAGCGCTTTTACCAATCGTTGCACGCAGAAAAGCTTACACCTTATGTTATGTCTTATGACGATATCATTTCA
TTTTGTAAAGAGAACAATATCTCTGAAGTAGTGATTGCGGGTGATATTATGAGTTATCATCTTGAAGAATATGATATTTT
ACATCAACGTTCTTTATTCAATGAAGCACGTATTGCCGTTACTTTAATTCGTGGGAATCATTACTTTAAAGCGAGTAAAA
CAATGAATCAACAAGGGGAGCCATACAAAGTTTTTACTAGTTTCTATAGAAAATGGCGACCTTACTTGAGGCATAGAGAC
GTATATCACTATGATTTAAAATCATTCGAAGACTTTGTCATTGCATCACCTGATGATTTAGTGTTTGATGACATAGCGTT
TGGATCCTCACAAGTAATTGAACAGAATAAATGGCAACATTTTTTAGATCAAGATATACAGAATTACGAAAGCGGAAGAG
ACTATTTACCTGAAGTGTTAACAAGTCAGCTAAGTGTTGCTTTAGCATATGGATTATTAGATATTATTGAAATTTTTAAT
GATTTATTGGCGCGTTATGATGAAGATGAGGCAAACCATGAAGCATTTATACGTGAACTCATTTTTAGAGAATTTTATTA
TGTGTTAATGACACAGTATCCAGAAACCTCATACCAAGCTTTCAAACCTAAATATCGACAGATAAAATGGTCGCAAAATG
AAGCGAATTTTAATGCATGGTGCGAAGGGCAAACAGGATTTCCAATCATTGATGCAGCAATAATGGAATTGACACAAACT
GGTTTTATGCATAATCGAATGAGAATGGTTGTGTCGCAATTTTTAACCAAAGATTTATTTATAGATTGGACATGGGGAGA
AAAATTCTTTAGAAAGCACCTTATTGACTATGATGCAGCATCAAATATTCATGGATGGCAATGGTCTGCTTCTACAGGTA
CGGATGCAGTGCCGTATTTTAGAATGTTTAATCCAATAAGACAGAGTGAACGCTTTGATGCTAAAGCTTTGTATATCAAA
ACATATCTTCCGATTTTTAATCAAATTGATGCAAAATATTTGCATGATACACAACGCAATGAGTCCAACCTTTTTGAACA
GGGGATTGAATTAGGTAGTCATTATCCAAGACAAATGGTAGATCATCAAGAAAAACGTACACAAGTTTTAGCTACATTTA
AAGCGCTAGACTAA

Upstream 100 bases:

>100_bases
TTAGGTTTGCTTTAATTAAAAATATAAATAAGAATCTAGGTTATTTTAAAGTGACAAAAAGCTTAATAAAATAAAAAGAT
AATTGAAGGGTGTTTTGTTT

Downstream 100 bases:

>100_bases
TTCGGCTCAATTGATAGATCTGGCATGAGTAAAATCTGGAGCAGAATATAAAGTTCTTAAGCAATATAAATAAGCCAATT
TCTATTATTGATGTGATAGA

Product: deoxyribodipyrimidine photo-lyase

Products: NA

Alternate protein names: DNA photolyase; Photoreactivating enzyme [H]

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MAIAVLLNRMFRMEHNPLFEYIYQQKEDIDACYFIIPEEDMSSASDLKAQFYRGTLQRFYQSLHAEKLTPYVMSYDDIIS
FCKENNISEVVIAGDIMSYHLEEYDILHQRSLFNEARIAVTLIRGNHYFKASKTMNQQGEPYKVFTSFYRKWRPYLRHRD
VYHYDLKSFEDFVIASPDDLVFDDIAFGSSQVIEQNKWQHFLDQDIQNYESGRDYLPEVLTSQLSVALAYGLLDIIEIFN
DLLARYDEDEANHEAFIRELIFREFYYVLMTQYPETSYQAFKPKYRQIKWSQNEANFNAWCEGQTGFPIIDAAIMELTQT
GFMHNRMRMVVSQFLTKDLFIDWTWGEKFFRKHLIDYDAASNIHGWQWSASTGTDAVPYFRMFNPIRQSERFDAKALYIK
TYLPIFNQIDAKYLHDTQRNESNLFEQGIELGSHYPRQMVDHQEKRTQVLATFKALD

Sequences:

>Translated_457_residues
MAIAVLLNRMFRMEHNPLFEYIYQQKEDIDACYFIIPEEDMSSASDLKAQFYRGTLQRFYQSLHAEKLTPYVMSYDDIIS
FCKENNISEVVIAGDIMSYHLEEYDILHQRSLFNEARIAVTLIRGNHYFKASKTMNQQGEPYKVFTSFYRKWRPYLRHRD
VYHYDLKSFEDFVIASPDDLVFDDIAFGSSQVIEQNKWQHFLDQDIQNYESGRDYLPEVLTSQLSVALAYGLLDIIEIFN
DLLARYDEDEANHEAFIRELIFREFYYVLMTQYPETSYQAFKPKYRQIKWSQNEANFNAWCEGQTGFPIIDAAIMELTQT
GFMHNRMRMVVSQFLTKDLFIDWTWGEKFFRKHLIDYDAASNIHGWQWSASTGTDAVPYFRMFNPIRQSERFDAKALYIK
TYLPIFNQIDAKYLHDTQRNESNLFEQGIELGSHYPRQMVDHQEKRTQVLATFKALD
>Mature_456_residues
AIAVLLNRMFRMEHNPLFEYIYQQKEDIDACYFIIPEEDMSSASDLKAQFYRGTLQRFYQSLHAEKLTPYVMSYDDIISF
CKENNISEVVIAGDIMSYHLEEYDILHQRSLFNEARIAVTLIRGNHYFKASKTMNQQGEPYKVFTSFYRKWRPYLRHRDV
YHYDLKSFEDFVIASPDDLVFDDIAFGSSQVIEQNKWQHFLDQDIQNYESGRDYLPEVLTSQLSVALAYGLLDIIEIFND
LLARYDEDEANHEAFIRELIFREFYYVLMTQYPETSYQAFKPKYRQIKWSQNEANFNAWCEGQTGFPIIDAAIMELTQTG
FMHNRMRMVVSQFLTKDLFIDWTWGEKFFRKHLIDYDAASNIHGWQWSASTGTDAVPYFRMFNPIRQSERFDAKALYIKT
YLPIFNQIDAKYLHDTQRNESNLFEQGIELGSHYPRQMVDHQEKRTQVLATFKALD

Specific function: Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ul

COG id: COG0415

COG function: function code L; Deoxyribodipyrimidine photolyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DNA photolyase domain [H]

Homologues:

Organism=Homo sapiens, GI4758072, Length=470, Percent_Identity=24.8936170212766, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI188536103, Length=246, Percent_Identity=30.0813008130081, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI188536100, Length=246, Percent_Identity=29.6747967479675, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI1786926, Length=399, Percent_Identity=33.8345864661654, Blast_Score=219, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6324962, Length=475, Percent_Identity=28.4210526315789, Blast_Score=184, Evalue=3e-47,
Organism=Drosophila melanogaster, GI17137248, Length=302, Percent_Identity=28.1456953642384, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24585455, Length=302, Percent_Identity=28.1456953642384, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24648152, Length=202, Percent_Identity=28.7128712871287, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002081
- InterPro:   IPR018394
- InterPro:   IPR006050
- InterPro:   IPR005101
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00875 DNA_photolyase; PF03441 FAD_binding_7 [H]

EC number: =4.1.99.3 [H]

Molecular weight: Translated: 54384; Mature: 54253

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIAVLLNRMFRMEHNPLFEYIYQQKEDIDACYFIIPEEDMSSASDLKAQFYRGTLQRFY
CHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCHHCCCHHHHHHHHHHHHHHHHH
QSLHAEKLTPYVMSYDDIISFCKENNISEVVIAGDIMSYHLEEYDILHQRSLFNEARIAV
HHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEE
TLIRGNHYFKASKTMNQQGEPYKVFTSFYRKWRPYLRHRDVYHYDLKSFEDFVIASPDDL
EEEECCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECHHCCCCEEEECCCCC
VFDDIAFGSSQVIEQNKWQHFLDQDIQNYESGRDYLPEVLTSQLSVALAYGLLDIIEIFN
EEHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLARYDEDEANHEAFIRELIFREFYYVLMTQYPETSYQAFKPKYRQIKWSQNEANFNAW
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHCEEECCCCCCCCEE
CEGQTGFPIIDAAIMELTQTGFMHNRMRMVVSQFLTKDLFIDWTWGEKFFRKHLIDYDAA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHCCCCC
SNIHGWQWSASTGTDAVPYFRMFNPIRQSERFDAKALYIKTYLPIFNQIDAKYLHDTQRN
CCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHCCCC
ESNLFEQGIELGSHYPRQMVDHQEKRTQVLATFKALD
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIAVLLNRMFRMEHNPLFEYIYQQKEDIDACYFIIPEEDMSSASDLKAQFYRGTLQRFY
HHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCHHCCCHHHHHHHHHHHHHHHHH
QSLHAEKLTPYVMSYDDIISFCKENNISEVVIAGDIMSYHLEEYDILHQRSLFNEARIAV
HHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEE
TLIRGNHYFKASKTMNQQGEPYKVFTSFYRKWRPYLRHRDVYHYDLKSFEDFVIASPDDL
EEEECCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECHHCCCCEEEECCCCC
VFDDIAFGSSQVIEQNKWQHFLDQDIQNYESGRDYLPEVLTSQLSVALAYGLLDIIEIFN
EEHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLARYDEDEANHEAFIRELIFREFYYVLMTQYPETSYQAFKPKYRQIKWSQNEANFNAW
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHCEEECCCCCCCCEE
CEGQTGFPIIDAAIMELTQTGFMHNRMRMVVSQFLTKDLFIDWTWGEKFFRKHLIDYDAA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHCCCCC
SNIHGWQWSASTGTDAVPYFRMFNPIRQSERFDAKALYIKTYLPIFNQIDAKYLHDTQRN
CCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHCCCC
ESNLFEQGIELGSHYPRQMVDHQEKRTQVLATFKALD
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7678007 [H]