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The map label for this gene is walR

Identifier: 148266465

GI number: 148266465

Start: 24989

End: 25690

Strand: Direct

Name: walR

Synonym: SaurJH9_0018

Alternate gene names: 148266465

Gene position: 24989-25690 (Clockwise)

Preceding gene: 148266464

Following gene: 148266466

Centisome position: 0.86

GC content: 36.47

Gene sequence:

>702_bases
ATGGCTAGAAAAGTTGTTGTAGTTGATGATGAAAAACCGATTGCTGATATTTTAGAATTTAACTTAAAAAAAGAAGGATA
CGATGTGTACTGTGCATACGATGGTAATGATGCAGTCGACTTAATTTATGAAGAAGAACCAGACATCGTATTACTAGATA
TCATGTTACCTGGTCGTGATGGTATGGAAGTATGTCGTGAAGTGCGCAAAAAATACGAAATGCCAATAATAATGCTTACT
GCTAAAGATTCAGAAATTGATAAAGTGCTTGGTTTAGAACTAGGTGCAGATGACTATGTAACGAAACCGTTTAGTACGCG
TGAATTAATCGCACGTGTGAAAGCGAACTTACGTCGTCATTACTCACAACCAGCACAAGACACTGGAAATGTAACGAATG
AAATCACAATTAAAGATATTGTGATTTATCCAGACGCATATTCTATTAAAAAACGTGGCGAAGATATTGAATTAACACAT
CGTGAATTTGAATTGTTCCATTATTTATCAAAACATATGGGACAAGTAATGACACGTGAACATTTATTACAAACAGTATG
GGGCTATGATTACTTTGGCGATGTACGTACGGTCGATGTAACGATTCGTCGTTTACGTGAAAAGATTGAAGATGATCCGT
CACATCCTGAATATATTGTGACGCGTAGAGGCGTTGGATATTTCCTCCAACAACATGAGTAG

Upstream 100 bases:

>100_bases
ATAGTAAGCGACATCCTGTGATTTTTTACACAAACATAAACGATAAAGAACAAAAAATGATAAAATAATATTAATGATTT
AAGAAAAGAGGTTTATGCAA

Downstream 100 bases:

>100_bases
AGGTCGAAACGAATGAAGTGGCTAAAACAACTACAATCCCTTCATACTAAACTTGTAATTGTTTATGTATTACTGATTAT
CATTGGTATGCAAATTATCG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRDGMEVCREVRKKYEMPIIMLT
AKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHYSQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIELTH
REFELFHYLSKHMGQVMTREHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGYFLQQHE

Sequences:

>Translated_233_residues
MARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRDGMEVCREVRKKYEMPIIMLT
AKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHYSQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIELTH
REFELFHYLSKHMGQVMTREHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGYFLQQHE
>Mature_232_residues
ARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRDGMEVCREVRKKYEMPIIMLTA
KDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHYSQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIELTHR
EFELFHYLSKHMGQVMTREHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGYFLQQHE

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=39.1304347826087, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=40.5286343612335, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=36.8888888888889, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=35.7142857142857, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=37.3333333333333, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=35.5263157894737, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=35.6521739130435, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=33.9285714285714, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=34.7639484978541, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790860, Length=239, Percent_Identity=37.6569037656904, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=35.3191489361702, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=31.4410480349345, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=31.6017316017316, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=32.3144104803493, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=35.5140186915888, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790299, Length=143, Percent_Identity=32.1678321678322, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): WALR_STAA1 (A7WWQ5)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001440608.1
- ProteinModelPortal:   A7WWQ5
- STRING:   A7WWQ5
- EnsemblBacteria:   EBSTAT00000003939
- GeneID:   5561630
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_0018
- eggNOG:   COG0745
- GeneTree:   EBGT00050000024053
- HOGENOM:   HBG753323
- ProtClustDB:   CLSK2391091
- BioCyc:   SAUR418127:SAHV_0018-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00448
- SMART:   SM00862

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 27192; Mature: 27061

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRD
CCCEEEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCEEEEEEEECCCC
GMEVCREVRKKYEMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRH
HHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHH
YSQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIELTHREFELFHYLSKHMGQVMTRE
CCCCCCCCCCCCCEEEEEEEEECCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
HLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGYFLQQHE
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHCCCC
>Mature Secondary Structure 
ARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRD
CCEEEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCEEEEEEEECCCC
GMEVCREVRKKYEMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRH
HHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHH
YSQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIELTHREFELFHYLSKHMGQVMTRE
CCCCCCCCCCCCCEEEEEEEEECCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
HLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGYFLQQHE
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA