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The map label for this gene is nhaA3 [H]

Identifier: 148243688

GI number: 148243688

Start: 67582

End: 68019

Strand: Direct

Name: nhaA3 [H]

Synonym: Acry_3162

Alternate gene names: 148243688

Gene position: 67582-68019 (Clockwise)

Preceding gene: 148243687

Following gene: 148243689

Centisome position: 33.2

GC content: 62.56

Gene sequence:

>438_bases
TTGTCGCCCGTCGAGAGGCTCGAGGCCATGCTCCATCCCTGGGTCGCCTTCGGCGTTATGCCGCTTTTCGCGCTTGCAAA
CGCGGGGGTACCGATCACGATCAAGGGACTTATCAACCCAGTCTCGCTGGCGGTGATGGCGGGCTTCGTCCTCGGCAAGC
CGATCGGCGTCACAGCATTCGCATGGCTGGGGGTGCGCACGGGTGTCGCCATTCGGCCGGCGGGGCTCACCTGGGGGGGA
CTTGTCGGTGGGGCTCTTCTTACCGGTATCGGATTCACCATGGCGCTGTTTATCGCCGGCCAGGCATTTCAAGATGCCAC
GCTCAACGCAGCGAAGCTGGGTATCCTTGCTGCCTCAGTCGTCTCTTCTGTTGCTGGTCTCACGCTGCTGTGCGCGTTGC
CTCGGAGTGACGGAACGCTCGATGCCGATTTCCACTGA

Upstream 100 bases:

>100_bases
CCAACGCCCCAAAAATGTAGTGGCAACACCCGCACGCGGGCAAATAAACTATTGATATCACCAGACTTTATAAAACCAAC
TGTCCAAGTGGGGCGAGACG

Downstream 100 bases:

>100_bases
ACCGGTCGTTGAGCGCCCGGGTCAGCGTCAGACGTTCAGCGCTGCGTCGGCCGTCAACGCCAAGGGCGGGTTCTGGTACT
GCACCTATGAGGGCGGCCTG

Product: Na+/H+ antiporter NhaA

Products: Na (I) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: Sodium/proton antiporter nhaA 3 [H]

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MSPVERLEAMLHPWVAFGVMPLFALANAGVPITIKGLINPVSLAVMAGFVLGKPIGVTAFAWLGVRTGVAIRPAGLTWGG
LVGGALLTGIGFTMALFIAGQAFQDATLNAAKLGILAASVVSSVAGLTLLCALPRSDGTLDADFH

Sequences:

>Translated_145_residues
MSPVERLEAMLHPWVAFGVMPLFALANAGVPITIKGLINPVSLAVMAGFVLGKPIGVTAFAWLGVRTGVAIRPAGLTWGG
LVGGALLTGIGFTMALFIAGQAFQDATLNAAKLGILAASVVSSVAGLTLLCALPRSDGTLDADFH
>Mature_144_residues
SPVERLEAMLHPWVAFGVMPLFALANAGVPITIKGLINPVSLAVMAGFVLGKPIGVTAFAWLGVRTGVAIRPAGLTWGGL
VGGALLTGIGFTMALFIAGQAFQDATLNAAKLGILAASVVSSVAGLTLLCALPRSDGTLDADFH

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG3004

COG function: function code P; Na+/H+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaA Na(+)/H(+) (TC 2.A.33) antiporter family [H]

Homologues:

Organism=Escherichia coli, GI1786201, Length=135, Percent_Identity=45.9259259259259, Blast_Score=113, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670 [H]

Pfam domain/function: PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 14712; Mature: 14580

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPVERLEAMLHPWVAFGVMPLFALANAGVPITIKGLINPVSLAVMAGFVLGKPIGVTAF
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHCHHHHHHHHHHHHCCCCCHHHH
AWLGVRTGVAIRPAGLTWGGLVGGALLTGIGFTMALFIAGQAFQDATLNAAKLGILAASV
HHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHH
VSSVAGLTLLCALPRSDGTLDADFH
HHHHHHHHHHEECCCCCCCCCCCCC
>Mature Secondary Structure 
SPVERLEAMLHPWVAFGVMPLFALANAGVPITIKGLINPVSLAVMAGFVLGKPIGVTAF
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHCHHHHHHHHHHHHCCCCCHHHH
AWLGVRTGVAIRPAGLTWGGLVGGALLTGIGFTMALFIAGQAFQDATLNAAKLGILAASV
HHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHH
VSSVAGLTLLCALPRSDGTLDADFH
HHHHHHHHHHEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: Na (I) [Cytoplasm] + 2 Proton [Periplasm] = Na (I) [Periplasm] + 2 Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA