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The map label for this gene is nhaA3 [H]

Identifier: 148243686

GI number: 148243686

Start: 64741

End: 65721

Strand: Direct

Name: nhaA3 [H]

Synonym: Acry_3160

Alternate gene names: 148243686

Gene position: 64741-65721 (Clockwise)

Preceding gene: 148243685

Following gene: 148243687

Centisome position: 31.8

GC content: 58.92

Gene sequence:

>981_bases
TTGATTACGGACCAGAACAGTAAGCCGCAGCAAGGCGAACTGCCGACCACACACATCGACGCGCTGACCAACTCGTTTTC
GCAGTTCCTGCGCATCGAAGCCACGAGTGGTGCCGTTCTCCTGTTGGCCACCGTCGTTGCATTGACGCTTTCCAACTCAC
CCTGGTCCGATGGCTTCAGATCTCTTTGGGAGACACCAATCGGCATTCAGATCGGTGCGTTCCAGTTTCTGCGCTCTTTG
CGGGATCTGATCAACGACGGTCTAATGACGCTGTTCTTCTTCATCGTCGCGCTCGAGATCAAGCGCGAAGTGGTGCTTGG
TGAACTTCGGAACCCGCGCATGGTGGCTCTCTCGGTCGTAGCTGCGGCAGGAGGCATGCTTGTGCCCATGGGCTTGTATC
TGGCGCTGCAGCATGGCCAACCTGGGCAGCATGGTTGGGGCGTCGTGATGCCGACCGACACAGCTTTCGTCATCGGCTGC
CTGGCGCTCCTTGGTTCGCGTGTGCCTCCGGGCCTACGCGTCTTCCTGCTATCGCTTGCGGTCGTCGACGACCTTGCCGC
CATCCTCGTGGTCGCCGTCGGTTACAGTCGATCAATCGACTGGACTGCCCTTGCGCTCGGCGCCGTCGGACTGGTGATAA
TTCGGGGGATGGCATTACTCGGCGTTCGTAACATCCGCGTCTACTTTCTGGCTGGGGCAATAATCTGGCTCGCCGTCAAT
GCGTCCGGCATCCACGCGACGATTGTTGGTGTTATCCTCGGGCTCATGACACCGACGGCTGGCTGGGTGAGCGACCAGCG
TCTGGGGGAAATCTTGCGAAAGGTGCTCTCCTATCCCCCGGGAGATCATTGGAGTGGCGATACCGAGGATAACCGGGCGC
TGCAGGTTGCCGGTATCGCGGTGCGCGAGACCCGAGTTGGACAGTGGGGTGAGAACGGATGGGGAACGAATGGATATAAG
TCATTGATATATAATGGGTGA

Upstream 100 bases:

>100_bases
CAGCCTGATGCCGGGAAAAATTGGGCTTGCCGGGACGGGTAACCGCCTCGACACCCCGGGCGGGGTGGGTTTTCTCGAGA
TATAAGGGGAGATGGCCGAT

Downstream 100 bases:

>100_bases
CATTTGGGCGCGAAAAATGTGTAGTAACAACAGTTTTGGCTGAATGGCAGTTTTTTGTTGAATTCGGCATGGCATTGCCG
TCACAACATCAGCATGTTCG

Product: Na+/H+ antiporter NhaA

Products: Na (I) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: Sodium/proton antiporter nhaA 3 [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MITDQNSKPQQGELPTTHIDALTNSFSQFLRIEATSGAVLLLATVVALTLSNSPWSDGFRSLWETPIGIQIGAFQFLRSL
RDLINDGLMTLFFFIVALEIKREVVLGELRNPRMVALSVVAAAGGMLVPMGLYLALQHGQPGQHGWGVVMPTDTAFVIGC
LALLGSRVPPGLRVFLLSLAVVDDLAAILVVAVGYSRSIDWTALALGAVGLVIIRGMALLGVRNIRVYFLAGAIIWLAVN
ASGIHATIVGVILGLMTPTAGWVSDQRLGEILRKVLSYPPGDHWSGDTEDNRALQVAGIAVRETRVGQWGENGWGTNGYK
SLIYNG

Sequences:

>Translated_326_residues
MITDQNSKPQQGELPTTHIDALTNSFSQFLRIEATSGAVLLLATVVALTLSNSPWSDGFRSLWETPIGIQIGAFQFLRSL
RDLINDGLMTLFFFIVALEIKREVVLGELRNPRMVALSVVAAAGGMLVPMGLYLALQHGQPGQHGWGVVMPTDTAFVIGC
LALLGSRVPPGLRVFLLSLAVVDDLAAILVVAVGYSRSIDWTALALGAVGLVIIRGMALLGVRNIRVYFLAGAIIWLAVN
ASGIHATIVGVILGLMTPTAGWVSDQRLGEILRKVLSYPPGDHWSGDTEDNRALQVAGIAVRETRVGQWGENGWGTNGYK
SLIYNG
>Mature_326_residues
MITDQNSKPQQGELPTTHIDALTNSFSQFLRIEATSGAVLLLATVVALTLSNSPWSDGFRSLWETPIGIQIGAFQFLRSL
RDLINDGLMTLFFFIVALEIKREVVLGELRNPRMVALSVVAAAGGMLVPMGLYLALQHGQPGQHGWGVVMPTDTAFVIGC
LALLGSRVPPGLRVFLLSLAVVDDLAAILVVAVGYSRSIDWTALALGAVGLVIIRGMALLGVRNIRVYFLAGAIIWLAVN
ASGIHATIVGVILGLMTPTAGWVSDQRLGEILRKVLSYPPGDHWSGDTEDNRALQVAGIAVRETRVGQWGENGWGTNGYK
SLIYNG

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG3004

COG function: function code P; Na+/H+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaA Na(+)/H(+) (TC 2.A.33) antiporter family [H]

Homologues:

Organism=Escherichia coli, GI1786201, Length=260, Percent_Identity=38.0769230769231, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670 [H]

Pfam domain/function: PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 34953; Mature: 34953

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITDQNSKPQQGELPTTHIDALTNSFSQFLRIEATSGAVLLLATVVALTLSNSPWSDGFR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCCCCHHHH
SLWETPIGIQIGAFQFLRSLRDLINDGLMTLFFFIVALEIKREVVLGELRNPRMVALSVV
HHHCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AAAGGMLVPMGLYLALQHGQPGQHGWGVVMPTDTAFVIGCLALLGSRVPPGLRVFLLSLA
HHCCCHHHHHHHHHEEECCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
VVDDLAAILVVAVGYSRSIDWTALALGAVGLVIIRGMALLGVRNIRVYFLAGAIIWLAVN
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
ASGIHATIVGVILGLMTPTAGWVSDQRLGEILRKVLSYPPGDHWSGDTEDNRALQVAGIA
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEE
VRETRVGQWGENGWGTNGYKSLIYNG
EECCCCCCCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MITDQNSKPQQGELPTTHIDALTNSFSQFLRIEATSGAVLLLATVVALTLSNSPWSDGFR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCCCCHHHH
SLWETPIGIQIGAFQFLRSLRDLINDGLMTLFFFIVALEIKREVVLGELRNPRMVALSVV
HHHCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AAAGGMLVPMGLYLALQHGQPGQHGWGVVMPTDTAFVIGCLALLGSRVPPGLRVFLLSLA
HHCCCHHHHHHHHHEEECCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
VVDDLAAILVVAVGYSRSIDWTALALGAVGLVIIRGMALLGVRNIRVYFLAGAIIWLAVN
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
ASGIHATIVGVILGLMTPTAGWVSDQRLGEILRKVLSYPPGDHWSGDTEDNRALQVAGIA
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEE
VRETRVGQWGENGWGTNGYKSLIYNG
EECCCCCCCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: Na (I) [Cytoplasm] + 2 Proton [Periplasm] = Na (I) [Periplasm] + 2 Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA