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The map label for this gene is citC [H]

Identifier: 147674487

GI number: 147674487

Start: 343888

End: 344958

Strand: Direct

Name: citC [H]

Synonym: VC0395_A0323

Alternate gene names: 147674487

Gene position: 343888-344958 (Clockwise)

Preceding gene: 147675073

Following gene: 147673924

Centisome position: 11.37

GC content: 45.56

Gene sequence:

>1071_bases
GTGAGGAAGCCGACCATGGTGGATATTTATACCTTCTCGCGAGTTTCAACCAAGAATCGAACCAAGCTCTTACAGATCAA
AGAGTTTCTCTGCCAGCATCAGCTGACCGTGGATGACGATGTCGAGCATTTTGTGGTGGCTTATGGCACAAACCAAATCA
TCGCTTGCGGCGGAATTGCGGGGCACGTGTTGAAGTCCATCGCGGTTTCTCCTGCGCTGCAAGGCACTGGTTTTGCGCTC
AAACTGATGACCGAATTAACCAACTTCGCTTATGAAATGGGGCGTTTTTCACTCTTTCTATTTACTAAGCCAGCCAATAT
TGATTTATTTAGACAGTGTGGTTTTTTCTTGGTCGATAAAGTCGAACCGCATATTGCTTTATTAGAAAATAGCCCTAATC
GCCTTTCTGTTTATTGCAAACAGTTGCAGTTATTAAAAATGTCTGGCCGTAAAATTGGCAGTATTGTGATGAATGCCAAT
CCATTTACCTTAGGTCATCAATATTTAATTGAACAAGCCTGTGAACAATGTGACTGGGTGCATTTATTTGTTGTAAAAGC
AGAGAATAAAGATTTTTCTTACGCTGATCGCATGGCCATGATTAAGGCGGGTAGTAAACATTTATTGAATTTAACTATTC
ATTCCGGTTCAGATTATATTATTTCGCGCGCGACCTTCCCCAGTTATTTTATTAAAGATCAGCAAGTGGTCAATCAATCC
CATACCGCGCTGGATTTAAGTATTTTCCGCCATTCGATCGCGCCTGCCCTTGGCATTACGCACCGCTTTGTCGGTAGTGA
GCCGATTTGTACGGTGACGCGTCACTACAACCAAGCCATGCGCCGCTGGCTAGAAGAAGCGCACGATGCCAGTGCGTCGA
TCCAAGTGGTTGAAATTGAGCGCAGTCAGCAAGCCTCGCAGCCAATTTCAGCATCGCGCGTGCGTTACTTGCTCAAACAA
TTTGGCGTTGCTGCGATTGCCGATCTCGTGCCAAAAACGACCTATTCCTACCTTTGCCAGCACTATGCGGAACATTCGCT
ACAGACCGCACCGCAACGGTTAGCGGTATGA

Upstream 100 bases:

>100_bases
ATTCATTAAAACCATAAAGAGCGTTAACGGCGGGAAATAAAGTGATTACCCTCATTAAACCTTTTCGGCTGAATTTAGAT
AATAAAGCCAGAAAAAATAG

Downstream 100 bases:

>100_bases
GCGCGGTGCTGACACTGTTTTATCCAATAACTCATTAACAAGGTTGTACCCATGAAAATTGCCCATCCCGCCTTTGCGGG
AACACTGGAATCCAGTGATC

Product: citrate (pro-3S)-lyase ligase

Products: NA

Alternate protein names: Acetate:SH-citrate lyase ligase; Citrate lyase synthetase [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MRKPTMVDIYTFSRVSTKNRTKLLQIKEFLCQHQLTVDDDVEHFVVAYGTNQIIACGGIAGHVLKSIAVSPALQGTGFAL
KLMTELTNFAYEMGRFSLFLFTKPANIDLFRQCGFFLVDKVEPHIALLENSPNRLSVYCKQLQLLKMSGRKIGSIVMNAN
PFTLGHQYLIEQACEQCDWVHLFVVKAENKDFSYADRMAMIKAGSKHLLNLTIHSGSDYIISRATFPSYFIKDQQVVNQS
HTALDLSIFRHSIAPALGITHRFVGSEPICTVTRHYNQAMRRWLEEAHDASASIQVVEIERSQQASQPISASRVRYLLKQ
FGVAAIADLVPKTTYSYLCQHYAEHSLQTAPQRLAV

Sequences:

>Translated_356_residues
MRKPTMVDIYTFSRVSTKNRTKLLQIKEFLCQHQLTVDDDVEHFVVAYGTNQIIACGGIAGHVLKSIAVSPALQGTGFAL
KLMTELTNFAYEMGRFSLFLFTKPANIDLFRQCGFFLVDKVEPHIALLENSPNRLSVYCKQLQLLKMSGRKIGSIVMNAN
PFTLGHQYLIEQACEQCDWVHLFVVKAENKDFSYADRMAMIKAGSKHLLNLTIHSGSDYIISRATFPSYFIKDQQVVNQS
HTALDLSIFRHSIAPALGITHRFVGSEPICTVTRHYNQAMRRWLEEAHDASASIQVVEIERSQQASQPISASRVRYLLKQ
FGVAAIADLVPKTTYSYLCQHYAEHSLQTAPQRLAV
>Mature_356_residues
MRKPTMVDIYTFSRVSTKNRTKLLQIKEFLCQHQLTVDDDVEHFVVAYGTNQIIACGGIAGHVLKSIAVSPALQGTGFAL
KLMTELTNFAYEMGRFSLFLFTKPANIDLFRQCGFFLVDKVEPHIALLENSPNRLSVYCKQLQLLKMSGRKIGSIVMNAN
PFTLGHQYLIEQACEQCDWVHLFVVKAENKDFSYADRMAMIKAGSKHLLNLTIHSGSDYIISRATFPSYFIKDQQVVNQS
HTALDLSIFRHSIAPALGITHRFVGSEPICTVTRHYNQAMRRWLEEAHDASASIQVVEIERSQQASQPISASRVRYLLKQ
FGVAAIADLVPKTTYSYLCQHYAEHSLQTAPQRLAV

Specific function: Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase [H]

COG id: COG3053

COG function: function code C; Citrate lyase synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI87081765, Length=342, Percent_Identity=50.5847953216374, Blast_Score=350, Evalue=9e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005216
- InterPro:   IPR013166
- InterPro:   IPR004821
- InterPro:   IPR014729 [H]

Pfam domain/function: PF08218 Citrate_ly_lig [H]

EC number: =6.2.1.22 [H]

Molecular weight: Translated: 40164; Mature: 40164

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKPTMVDIYTFSRVSTKNRTKLLQIKEFLCQHQLTVDDDVEHFVVAYGTNQIIACGGIA
CCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEECCHH
GHVLKSIAVSPALQGTGFALKLMTELTNFAYEMGRFSLFLFTKPANIDLFRQCGFFLVDK
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCEEEEC
VEPHIALLENSPNRLSVYCKQLQLLKMSGRKIGSIVMNANPFTLGHQYLIEQACEQCDWV
CCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCEE
HLFVVKAENKDFSYADRMAMIKAGSKHLLNLTIHSGSDYIISRATFPSYFIKDQQVVNQS
EEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCCHHHHCHHHHHCCC
HTALDLSIFRHSIAPALGITHRFVGSEPICTVTRHYNQAMRRWLEEAHDASASIQVVEIE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
RSQQASQPISASRVRYLLKQFGVAAIADLVPKTTYSYLCQHYAEHSLQTAPQRLAV
CHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure
MRKPTMVDIYTFSRVSTKNRTKLLQIKEFLCQHQLTVDDDVEHFVVAYGTNQIIACGGIA
CCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEECCHH
GHVLKSIAVSPALQGTGFALKLMTELTNFAYEMGRFSLFLFTKPANIDLFRQCGFFLVDK
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCEEEEC
VEPHIALLENSPNRLSVYCKQLQLLKMSGRKIGSIVMNANPFTLGHQYLIEQACEQCDWV
CCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCEE
HLFVVKAENKDFSYADRMAMIKAGSKHLLNLTIHSGSDYIISRATFPSYFIKDQQVVNQS
EEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCCHHHHCHHHHHCCC
HTALDLSIFRHSIAPALGITHRFVGSEPICTVTRHYNQAMRRWLEEAHDASASIQVVEIE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
RSQQASQPISASRVRYLLKQFGVAAIADLVPKTTYSYLCQHYAEHSLQTAPQRLAV
CHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]