Click here to switch to the map view.

The map label for this gene is deoC

Identifier: 147674428

GI number: 147674428

Start: 2060303

End: 2061082

Strand: Reverse

Name: deoC

Synonym: VC0395_A1929

Alternate gene names: 147674428

Gene position: 2061082-2060303 (Counterclockwise)

Preceding gene: 147673370

Following gene: 147673836

Centisome position: 68.16

GC content: 48.46

Gene sequence:

>780_bases
ATGAGCGAATTAAAAGTAGCAGCTCTACGTGCACTGAAACTGATGGATCTCACCACGTTGAATGACAACGATACGGATGC
CAAAGTGATCCAACTTTGTCATGATGCGAAAAGTCCAGTCGGCAACACGGCTGCCATTTGTATTTACCCTCGCTTTATTC
CTATTGCTAAGAAGACACTTCGCGAGCAAGGAACCCCTGAAATCCGTATTGCTACGGTAACCAATTTTCCTCACGGTAAT
GACGATATTGAAATCGCCGTTGCTGAAACGAAAGCCGCTGTTGCTTACGGTGCTGATGAAGTGGATGTGGTATTCCCATA
TCGCGCTCTGATCGCAGGCAACGAGCAAGTCGGTTTTGATCTGGTGAAACAGTGTAAAGCGGCTTGTGGCGACAAAGTGC
TACTGAAAGTGATCATCGAAACTGGTGAGCTGAAACAAGAAGCGCTGATCAAAAAAGCCTCTCAAATCTGTATTGAAGCT
GGCGCAGATTTCATCAAGACCTCAACCGGCAAAGTGCCAGTAAATGCGACACCAGAATATGCACGCATGATGCTGGAAGT
GATCCGTGATATGGGCGTAGCCAAAACCGTCGGTTTCAAACCTGCCGGTGGTGTTCGTACCGCAGAAGATGCGCAGCAAT
ATCTGGCCATGGCCGATGAGATCCTCGGTGGCGATTGGGCAGACAGCCGTCACTACCGTTTCGGCGCTTCAAGCCTACTG
ACTAACCTTCTGAATACATTAGAAGTGACAGACCAAAAGGCAGATCCTGCCGCTTACTAA

Upstream 100 bases:

>100_bases
GAGTCTTCAAGGAACCAAGTCCGTTCATTTGTGGCTGCTCAGCAGAAAATAGTACTCTGCTGGGGAGTGAACTAGATGAC
TATATTGATCGGAGATAGAA

Downstream 100 bases:

>100_bases
TATCCATTGTGTCTGAGAGCAGCGCGAGGCTTCGCGCTGCTTAACCTCTTTACACTACGCAGTTTCTTTGGGAACTGGGA
GGCAGCTATGTCTTTATCTC

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSELKVAALRALKLMDLTTLNDNDTDAKVIQLCHDAKSPVGNTAAICIYPRFIPIAKKTLREQGTPEIRIATVTNFPHGN
DDIEIAVAETKAAVAYGADEVDVVFPYRALIAGNEQVGFDLVKQCKAACGDKVLLKVIIETGELKQEALIKKASQICIEA
GADFIKTSTGKVPVNATPEYARMMLEVIRDMGVAKTVGFKPAGGVRTAEDAQQYLAMADEILGGDWADSRHYRFGASSLL
TNLLNTLEVTDQKADPAAY

Sequences:

>Translated_259_residues
MSELKVAALRALKLMDLTTLNDNDTDAKVIQLCHDAKSPVGNTAAICIYPRFIPIAKKTLREQGTPEIRIATVTNFPHGN
DDIEIAVAETKAAVAYGADEVDVVFPYRALIAGNEQVGFDLVKQCKAACGDKVLLKVIIETGELKQEALIKKASQICIEA
GADFIKTSTGKVPVNATPEYARMMLEVIRDMGVAKTVGFKPAGGVRTAEDAQQYLAMADEILGGDWADSRHYRFGASSLL
TNLLNTLEVTDQKADPAAY
>Mature_258_residues
SELKVAALRALKLMDLTTLNDNDTDAKVIQLCHDAKSPVGNTAAICIYPRFIPIAKKTLREQGTPEIRIATVTNFPHGND
DIEIAVAETKAAVAYGADEVDVVFPYRALIAGNEQVGFDLVKQCKAACGDKVLLKVIIETGELKQEALIKKASQICIEAG
ADFIKTSTGKVPVNATPEYARMMLEVIRDMGVAKTVGFKPAGGVRTAEDAQQYLAMADEILGGDWADSRHYRFGASSLLT
NLLNTLEVTDQKADPAAY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 2 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=252, Percent_Identity=38.8888888888889, Blast_Score=166, Evalue=2e-41,
Organism=Escherichia coli, GI1790841, Length=236, Percent_Identity=81.7796610169492, Blast_Score=399, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17533015, Length=245, Percent_Identity=39.1836734693878, Blast_Score=158, Evalue=3e-39,
Organism=Drosophila melanogaster, GI19922098, Length=256, Percent_Identity=36.71875, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_VIBC3 (A5F5S6)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F5S6
- SMR:   A5F5S6
- STRING:   A5F5S6
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A1929
- eggNOG:   COG0274
- HOGENOM:   HBG636421
- OMA:   CKEACGD
- ProtClustDB:   PRK05283
- BioCyc:   VCHO345073:VC0395_A1929-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00592
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 27959; Mature: 27828

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: ACT_SITE 166-166 ACT_SITE 200-200

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELKVAALRALKLMDLTTLNDNDTDAKVIQLCHDAKSPVGNTAAICIYPRFIPIAKKTL
CCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHH
REQGTPEIRIATVTNFPHGNDDIEIAVAETKAAVAYGADEVDVVFPYRALIAGNEQVGFD
HHCCCCCEEEEEEECCCCCCCCEEEEEECCCCCEEECCCCEEEEECHHHHHCCCCCCCHH
LVKQCKAACGDKVLLKVIIETGELKQEALIKKASQICIEAGADFIKTSTGKVPVNATPEY
HHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHH
ARMMLEVIRDMGVAKTVGFKPAGGVRTAEDAQQYLAMADEILGGDWADSRHYRFGASSLL
HHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHH
TNLLNTLEVTDQKADPAAY
HHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SELKVAALRALKLMDLTTLNDNDTDAKVIQLCHDAKSPVGNTAAICIYPRFIPIAKKTL
CCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHH
REQGTPEIRIATVTNFPHGNDDIEIAVAETKAAVAYGADEVDVVFPYRALIAGNEQVGFD
HHCCCCCEEEEEEECCCCCCCCEEEEEECCCCCEEECCCCEEEEECHHHHHCCCCCCCHH
LVKQCKAACGDKVLLKVIIETGELKQEALIKKASQICIEAGADFIKTSTGKVPVNATPEY
HHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHH
ARMMLEVIRDMGVAKTVGFKPAGGVRTAEDAQQYLAMADEILGGDWADSRHYRFGASSLL
HHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHH
TNLLNTLEVTDQKADPAAY
HHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA