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The map label for this gene is estR [H]

Identifier: 147673590

GI number: 147673590

Start: 278203

End: 279108

Strand: Direct

Name: estR [H]

Synonym: VC0395_A0265

Alternate gene names: 147673590

Gene position: 278203-279108 (Clockwise)

Preceding gene: 147674474

Following gene: 147675709

Centisome position: 9.2

GC content: 47.68

Gene sequence:

>906_bases
ATGAATAAATGGCCAAGCCTCAAGCAGTTATCTTATTTGGTGACACTTTATGAAACCCGCCATTTTAGTGAGGCGGCTGA
GCGTTGCTTTGTCAGTCAATCGACCTTAAGTAAAGGCATTCAAAACCTTGAAGAGTTGATCGGCTGTTCCTTGTATGAAA
AGCAAGATAAGAAAAGCCCTCTGGTATTTACTCGGGTCGGAGAGTTGGTGGTCAAGCAGGGGCGAGAATTGCTCGCCAAG
GGGCAAGATTTAGTCGAGCTTGGTAAGTTGTGCCAAGGTGACACCATGGAAGGGCAATTGCGTTTGGGGTGCATTCCAAC
CATTGCGCCGTTTTTGTTGTGTGATTTAGTCCAAGAGATTAACCAGCGTTACCCTAAATTGCACTTATTGTTGCGCGAAG
ATACCACGGCAAATCTGCTTTCCGCCTTGCGCAGTGGTGAACTGGATGTGTTGATCCTCGCCTTACCCGTCGATATTGGC
AATATGGAGAGCTATGTGGTGGGGCAAGATCCGTTTCGTATGGTGATCAGCCGTAACCAAGTTAATCAGATCCGCGTGCC
GATCCGCTACGCTGATCTACCCGATGAATCGGTGTTTTTACTCGAAAACGAGCACTGTTTAACTGAACATGCCGTATCGG
CTTGTAAGCTCACCGATAAAGAGAAGATTAATCCATTTACCGCGGCCAGTTTGCATACCTTAGTGCAAATGGTGGCCAAT
GGCTTAGGTACGACTTTTATTCCGCAAATGGCCATCGACCACGGTTTGCTGGATAACCAAAATCTGGTGGTGATCGACCC
TCCTGGGCAAAAAGCTTACCGAGAAATCGGCCTAGTGTGGCGTCCAAGTTCTTCCCGAATTCACACTTTTCGCCAGTTAG
CTGAGATAGTGGCTGAGCTGTTATAG

Upstream 100 bases:

>100_bases
ATTAAGTTAATCGAAAAAAGCGATAAGTCTCGGTGAGGTCAGTAGTGCCTAGGTACCATGATGTTTTTAGCGCGGTTTTT
GATGAGAGGATGGAAGATGT

Downstream 100 bases:

>100_bases
CGATTGGTCGTAGTGATAATTCTGCTATGGACTAGTGAAAGCGCATTGTCAACGATGCGCTTTTTAGCATTTTGTGTGGT
TAGTGATTTTTTAATTGTGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Esterase operon transcriptional regulator [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNKWPSLKQLSYLVTLYETRHFSEAAERCFVSQSTLSKGIQNLEELIGCSLYEKQDKKSPLVFTRVGELVVKQGRELLAK
GQDLVELGKLCQGDTMEGQLRLGCIPTIAPFLLCDLVQEINQRYPKLHLLLREDTTANLLSALRSGELDVLILALPVDIG
NMESYVVGQDPFRMVISRNQVNQIRVPIRYADLPDESVFLLENEHCLTEHAVSACKLTDKEKINPFTAASLHTLVQMVAN
GLGTTFIPQMAIDHGLLDNQNLVVIDPPGQKAYREIGLVWRPSSSRIHTFRQLAEIVAELL

Sequences:

>Translated_301_residues
MNKWPSLKQLSYLVTLYETRHFSEAAERCFVSQSTLSKGIQNLEELIGCSLYEKQDKKSPLVFTRVGELVVKQGRELLAK
GQDLVELGKLCQGDTMEGQLRLGCIPTIAPFLLCDLVQEINQRYPKLHLLLREDTTANLLSALRSGELDVLILALPVDIG
NMESYVVGQDPFRMVISRNQVNQIRVPIRYADLPDESVFLLENEHCLTEHAVSACKLTDKEKINPFTAASLHTLVQMVAN
GLGTTFIPQMAIDHGLLDNQNLVVIDPPGQKAYREIGLVWRPSSSRIHTFRQLAEIVAELL
>Mature_301_residues
MNKWPSLKQLSYLVTLYETRHFSEAAERCFVSQSTLSKGIQNLEELIGCSLYEKQDKKSPLVFTRVGELVVKQGRELLAK
GQDLVELGKLCQGDTMEGQLRLGCIPTIAPFLLCDLVQEINQRYPKLHLLLREDTTANLLSALRSGELDVLILALPVDIG
NMESYVVGQDPFRMVISRNQVNQIRVPIRYADLPDESVFLLENEHCLTEHAVSACKLTDKEKINPFTAASLHTLVQMVAN
GLGTTFIPQMAIDHGLLDNQNLVVIDPPGQKAYREIGLVWRPSSSRIHTFRQLAEIVAELL

Specific function: Transcriptional regulator of the esterase operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=295, Percent_Identity=36.6101694915254, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1788748, Length=255, Percent_Identity=24.7058823529412, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1787879, Length=283, Percent_Identity=27.5618374558304, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI157672245, Length=268, Percent_Identity=23.8805970149254, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI145693105, Length=255, Percent_Identity=23.1372549019608, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33779; Mature: 33779

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKWPSLKQLSYLVTLYETRHFSEAAERCFVSQSTLSKGIQNLEELIGCSLYEKQDKKSP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCC
LVFTRVGELVVKQGRELLAKGQDLVELGKLCQGDTMEGQLRLGCIPTIAPFLLCDLVQEI
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHH
NQRYPKLHLLLREDTTANLLSALRSGELDVLILALPVDIGNMESYVVGQDPFRMVISRNQ
HHCCCEEEEEEECCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEECCCHHHHHHHCCC
VNQIRVPIRYADLPDESVFLLENEHCLTEHAVSACKLTDKEKINPFTAASLHTLVQMVAN
CCEEEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHH
GLGTTFIPQMAIDHGLLDNQNLVVIDPPGQKAYREIGLVWRPSSSRIHTFRQLAEIVAEL
CCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHCCCEECCCCHHHHHHHHHHHHHHHH
L
C
>Mature Secondary Structure
MNKWPSLKQLSYLVTLYETRHFSEAAERCFVSQSTLSKGIQNLEELIGCSLYEKQDKKSP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCC
LVFTRVGELVVKQGRELLAKGQDLVELGKLCQGDTMEGQLRLGCIPTIAPFLLCDLVQEI
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHH
NQRYPKLHLLLREDTTANLLSALRSGELDVLILALPVDIGNMESYVVGQDPFRMVISRNQ
HHCCCEEEEEEECCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEECCCHHHHHHHCCC
VNQIRVPIRYADLPDESVFLLENEHCLTEHAVSACKLTDKEKINPFTAASLHTLVQMVAN
CCEEEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHH
GLGTTFIPQMAIDHGLLDNQNLVVIDPPGQKAYREIGLVWRPSSSRIHTFRQLAEIVAEL
CCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHCCCEECCCCHHHHHHHHHHHHHHHH
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA