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The map label for this gene is citE [H]

Identifier: 147673483

GI number: 147673483

Start: 345303

End: 346178

Strand: Direct

Name: citE [H]

Synonym: VC0395_A0325

Alternate gene names: 147673483

Gene position: 345303-346178 (Clockwise)

Preceding gene: 147673924

Following gene: 147674991

Centisome position: 11.42

GC content: 55.25

Gene sequence:

>876_bases
ATGACCAAACTTCGTCGCAGTATGTTATTTGTGCCGGGCGCGAATGCCGCCATGCTCAGTAATACCTTTATCTATCAACC
GGATTCGATCATGTTCGATCTGGAAGATTCGGTCGCGCTGCGTGAAAAAGACACCGCGCGGATGTTGGTGTTCCATGCGC
TGCAACACCCTATGTATCAAGAGATGGAAACCGTGGTGCGGGTCAATCCGCTCGATTCTGAATTCGGCATCAAAGACCTT
AATGCCGTGGTGCGCGGCGGAGCCAAAGTGGTGCGTCTGCCGAAAACCGATAACGCCAACGATGTGATTGAGATGGAAAA
AGTCATCGAGCAGATCGAGCGTGAATGCGGACGTGAAGTGGGTAGCACGCGTATGTTGGCCGCGATTGAAAGCGCGCAAG
GCATCAACAACGCGGTTGAGATTGCCTTTAGCTCCCGCCGCCTGATTGGGATTGCGCTCGGCGCGGAAGACTATGTGCGC
GATCTGCGCACGCAGCGTTCAGCGGAAGGGATTGAGCTGCTGTTTGCACGCGGCTCCATTCTGCAAGCGGCGCGTGCTGC
CGGGATCATGGCGTTTGATACCGTCTATTCCGATGCCAATAACGAAGAGGGATTTTTGCGTGAGGCGGAGCACATCAAGC
AGCTTGGCTTTGATGGCAAGTCACTGATTAACCCGCGCCAGATTGACCTGCTGCACAACGTGTTTGCCCCAACCCAAAAA
GAGGTCGATCACGCCATCGCAGTCATCGAAGCCGCCGAAGAAGCCGCGGCGAAAGGGCTGGGCGTGGTTTCCCTTAACGG
CAAAATGGTCGATGGGCCCATCATCGAACGCGCACGTTGGACACTGCAACGTGCTGAATCCGGCACCAAACACTAA

Upstream 100 bases:

>100_bases
TCGAAGACAAAGGTGCGCTGGATTGTGTGATCCGCGCGCGCGTACAGGCGGCGGTGATGCGCGCTTGTGATGTTCAGAAC
ATTGAGTGGAGTCAGCTATC

Downstream 100 bases:

>100_bases
AGGTCATCTCATGAGTATCAATACATTAAATAACCCTCTGTCTGTGCTGGAAGTGGAACGCTATGCGTTGACGCCTTACA
CCCAAGCGCACGCGATCACG

Product: citrate lyase, beta subunit

Products: NA

Alternate protein names: Citrase beta chain; Citrate (pro-3S)-lyase subunit beta; Citryl-CoA lyase subunit [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MTKLRRSMLFVPGANAAMLSNTFIYQPDSIMFDLEDSVALREKDTARMLVFHALQHPMYQEMETVVRVNPLDSEFGIKDL
NAVVRGGAKVVRLPKTDNANDVIEMEKVIEQIERECGREVGSTRMLAAIESAQGINNAVEIAFSSRRLIGIALGAEDYVR
DLRTQRSAEGIELLFARGSILQAARAAGIMAFDTVYSDANNEEGFLREAEHIKQLGFDGKSLINPRQIDLLHNVFAPTQK
EVDHAIAVIEAAEEAAAKGLGVVSLNGKMVDGPIIERARWTLQRAESGTKH

Sequences:

>Translated_291_residues
MTKLRRSMLFVPGANAAMLSNTFIYQPDSIMFDLEDSVALREKDTARMLVFHALQHPMYQEMETVVRVNPLDSEFGIKDL
NAVVRGGAKVVRLPKTDNANDVIEMEKVIEQIERECGREVGSTRMLAAIESAQGINNAVEIAFSSRRLIGIALGAEDYVR
DLRTQRSAEGIELLFARGSILQAARAAGIMAFDTVYSDANNEEGFLREAEHIKQLGFDGKSLINPRQIDLLHNVFAPTQK
EVDHAIAVIEAAEEAAAKGLGVVSLNGKMVDGPIIERARWTLQRAESGTKH
>Mature_290_residues
TKLRRSMLFVPGANAAMLSNTFIYQPDSIMFDLEDSVALREKDTARMLVFHALQHPMYQEMETVVRVNPLDSEFGIKDLN
AVVRGGAKVVRLPKTDNANDVIEMEKVIEQIERECGREVGSTRMLAAIESAQGINNAVEIAFSSRRLIGIALGAEDYVRD
LRTQRSAEGIELLFARGSILQAARAAGIMAFDTVYSDANNEEGFLREAEHIKQLGFDGKSLINPRQIDLLHNVFAPTQKE
VDHAIAVIEAAEEAAAKGLGVVSLNGKMVDGPIIERARWTLQRAESGTKH

Specific function: Represents a citryl-ACP lyase [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily [H]

Homologues:

Organism=Homo sapiens, GI45545437, Length=295, Percent_Identity=27.1186440677966, Blast_Score=113, Evalue=2e-25,
Organism=Escherichia coli, GI87081764, Length=285, Percent_Identity=77.1929824561403, Blast_Score=436, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17557458, Length=296, Percent_Identity=29.0540540540541, Blast_Score=125, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR006475
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.6; =4.1.3.34 [H]

Molecular weight: Translated: 32121; Mature: 31990

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLRRSMLFVPGANAAMLSNTFIYQPDSIMFDLEDSVALREKDTARMLVFHALQHPMYQ
CCCHHHCEEECCCCCHHHHCCEEEECCCCEEEECCCCHHHHCCCHHHHHHHHHHHCHHHH
EMETVVRVNPLDSEFGIKDLNAVVRGGAKVVRLPKTDNANDVIEMEKVIEQIERECGREV
HHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
GSTRMLAAIESAQGINNAVEIAFSSRRLIGIALGAEDYVRDLRTQRSAEGIELLFARGSI
CCHHHHHHHHHHCCCCHHEEEEECCCEEEEEEECCHHHHHHHHHHCCCCCCEEEECCCHH
LQAARAAGIMAFDTVYSDANNEEGFLREAEHIKQLGFDGKSLINPRQIDLLHNVFAPTQK
HHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCHH
EVDHAIAVIEAAEEAAAKGLGVVSLNGKMVDGPIIERARWTLQRAESGTKH
HHHHHHHHHHHHHHHHHCCCEEEEECCEEECCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TKLRRSMLFVPGANAAMLSNTFIYQPDSIMFDLEDSVALREKDTARMLVFHALQHPMYQ
CCHHHCEEECCCCCHHHHCCEEEECCCCEEEECCCCHHHHCCCHHHHHHHHHHHCHHHH
EMETVVRVNPLDSEFGIKDLNAVVRGGAKVVRLPKTDNANDVIEMEKVIEQIERECGREV
HHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
GSTRMLAAIESAQGINNAVEIAFSSRRLIGIALGAEDYVRDLRTQRSAEGIELLFARGSI
CCHHHHHHHHHHCCCCHHEEEEECCCEEEEEEECCHHHHHHHHHHCCCCCCEEEECCCHH
LQAARAAGIMAFDTVYSDANNEEGFLREAEHIKQLGFDGKSLINPRQIDLLHNVFAPTQK
HHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCHH
EVDHAIAVIEAAEEAAAKGLGVVSLNGKMVDGPIIERARWTLQRAESGTKH
HHHHHHHHHHHHHHHHHCCCEEEEECCEEECCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]