Click here to switch to the map view.

The map label for this gene is zraS [C]

Identifier: 146343865

GI number: 146343865

Start: 7427789

End: 7429372

Strand: Direct

Name: zraS [C]

Synonym: BRADO7116

Alternate gene names: 146343865

Gene position: 7427789-7429372 (Clockwise)

Preceding gene: 146343859

Following gene: 146343866

Centisome position: 99.61

GC content: 64.08

Gene sequence:

>1584_bases
ATGCTCACGCCGCACGGCGAGTGCCTGCTGTGGACGCCTGAATTGATTTGGGTGAACGCAGTCTCCGACGTCCTTATTTC
CGTCGCGTTCTTCACGATCGCTTTCGTGCTCGGCTACATCGTGTTTCGCCGCCGCGACTTCCAGTTCAGCTACATCTTCT
GGGCGTTCGCGCTGTGGGTGTCCGTCTGCGGACTGACGCGCCTGATCGAGGTGCTCACGCTCTGGGTGCCGGCCTATGTG
CTGGAGGCGGCGACGAAGGGCTTCCTGGCTTTCATGTCTGTCGGCATCGCCGCGGCGCTGATGCTCTTGTTGCCGAGGGT
TCTGACGATGCCTTCGCGCGCCGATTTGAAGCTCGCCTATGCGCAGCTCGAGGAGGAGACGCGGCAGCGGCGCACCGCCG
AGGCCATGGTCAAGCGCTTCCAGGAGATCGAGGCCACCGAGGCGCAGGTGCGTCAGGCGCAGAAGATGGAGGCGATCGGC
CAGCTCACCGGCGGCGTCGCCCACGACTTCAACAACATCCTGACCGTGATCACCGGCACGATTGAGATCCTCGCCGAGGC
AGTGAAGGACCGTCCGCAACTGGTGCAGATCACCAGCCTGATCAACTCGGCGGCGGCGCGCGGCGCCGACCTCACCAAGC
ACCTGCTGGCCTTCGCGCGGCGCCAGCCGCTGCAGCCGCGCAGCGTCGACATCAACGGCATGGTGGTCGACACCGCGCGG
CTGCTGCGCCGGACCCTCGGCGAGCAGATCGAGATCGAATCGATGCTGGCGCACGATTCCGCGCCGGCGATGATCGACCC
GAGCCAGCTGTCGACGGCGATCCTCAACCTCGCGCTGAACGCCCGCGACGCGATGCCGAACGGCGGCAAGCTCACGCTCG
AGACCAAGAACGTCCTGCTCGACGACGCCTATGCGCGAATGAATCCGGAGGTCATACCCGGCAACTACGTGATGATCGCG
GTCAGCGACACCGGCGAAGGCATTCCATCCAATCTGCTGGACAAGGTGTTCGAGCCGTTCTTCACCACCAAGGACGTCGG
CAAGGGCGTCGGCCTCGGACTCAGCATGGTGTACGGCTTCGTCAAGCAGTCCAACGGCCACATCAAGATCTACAGCGAGC
CCGGTCACGGCACGTCGGTGAAGCTGTATCTGCCGCAAGCTACGGCAGATGCTGACGTGCTGCTGCTGGAGGCCAGTCTG
GCCAGCATGGAGCGCGGTGACGAAACGATCCTGATCGTCGAGGACGATTCGCTGGTGCGCGAATATGTCATTGCGCAGAT
CAAGCGGCTTGGCTACACGACCTTGGCCGCGAGCAAGGCCGACGAGGCGCTGTCGCTGATCGACAGCCCGGCGCGCATCG
ATCTCTTGTTCACCGACATCATCATGCCCGGCGGAATGAACGGGCGTCAGCTCGCGATCGAGGCGCTGAAGCGGCGGCCG
AACCTGAAAGTGCTGTACACGTCCGGCTATACCGAGAACGCGATCGTGCATCACGGCCGCCTCGACGCCGGCGTGCTGCT
GCTCACCAAGCCGTATCAGAGTGCGGATCTCGCCCGCATGATCCGGACCGCGCTGAACACGTGA

Upstream 100 bases:

>100_bases
GTGCTCAACGGAAATTTGAATGATCTGCTAAGGGAACTGGCCCGGGCCGCGGGGACGACACGGTCCGTCGGCTGCACGTT
TGGGGACGCTGGAGATGTCG

Downstream 100 bases:

>100_bases
TTGGCCTTGCGGGCGACACATGATCCGGCTCTCATCGGCGCGCGTTGTGCGCTCACATCAAGCGCTGCATTCATTGAATG
CTGCGCGCCTGTCGACTGCG

Product: sensor histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MLTPHGECLLWTPELIWVNAVSDVLISVAFFTIAFVLGYIVFRRRDFQFSYIFWAFALWVSVCGLTRLIEVLTLWVPAYV
LEAATKGFLAFMSVGIAAALMLLLPRVLTMPSRADLKLAYAQLEEETRQRRTAEAMVKRFQEIEATEAQVRQAQKMEAIG
QLTGGVAHDFNNILTVITGTIEILAEAVKDRPQLVQITSLINSAAARGADLTKHLLAFARRQPLQPRSVDINGMVVDTAR
LLRRTLGEQIEIESMLAHDSAPAMIDPSQLSTAILNLALNARDAMPNGGKLTLETKNVLLDDAYARMNPEVIPGNYVMIA
VSDTGEGIPSNLLDKVFEPFFTTKDVGKGVGLGLSMVYGFVKQSNGHIKIYSEPGHGTSVKLYLPQATADADVLLLEASL
ASMERGDETILIVEDDSLVREYVIAQIKRLGYTTLAASKADEALSLIDSPARIDLLFTDIIMPGGMNGRQLAIEALKRRP
NLKVLYTSGYTENAIVHHGRLDAGVLLLTKPYQSADLARMIRTALNT

Sequences:

>Translated_527_residues
MLTPHGECLLWTPELIWVNAVSDVLISVAFFTIAFVLGYIVFRRRDFQFSYIFWAFALWVSVCGLTRLIEVLTLWVPAYV
LEAATKGFLAFMSVGIAAALMLLLPRVLTMPSRADLKLAYAQLEEETRQRRTAEAMVKRFQEIEATEAQVRQAQKMEAIG
QLTGGVAHDFNNILTVITGTIEILAEAVKDRPQLVQITSLINSAAARGADLTKHLLAFARRQPLQPRSVDINGMVVDTAR
LLRRTLGEQIEIESMLAHDSAPAMIDPSQLSTAILNLALNARDAMPNGGKLTLETKNVLLDDAYARMNPEVIPGNYVMIA
VSDTGEGIPSNLLDKVFEPFFTTKDVGKGVGLGLSMVYGFVKQSNGHIKIYSEPGHGTSVKLYLPQATADADVLLLEASL
ASMERGDETILIVEDDSLVREYVIAQIKRLGYTTLAASKADEALSLIDSPARIDLLFTDIIMPGGMNGRQLAIEALKRRP
NLKVLYTSGYTENAIVHHGRLDAGVLLLTKPYQSADLARMIRTALNT
>Mature_527_residues
MLTPHGECLLWTPELIWVNAVSDVLISVAFFTIAFVLGYIVFRRRDFQFSYIFWAFALWVSVCGLTRLIEVLTLWVPAYV
LEAATKGFLAFMSVGIAAALMLLLPRVLTMPSRADLKLAYAQLEEETRQRRTAEAMVKRFQEIEATEAQVRQAQKMEAIG
QLTGGVAHDFNNILTVITGTIEILAEAVKDRPQLVQITSLINSAAARGADLTKHLLAFARRQPLQPRSVDINGMVVDTAR
LLRRTLGEQIEIESMLAHDSAPAMIDPSQLSTAILNLALNARDAMPNGGKLTLETKNVLLDDAYARMNPEVIPGNYVMIA
VSDTGEGIPSNLLDKVFEPFFTTKDVGKGVGLGLSMVYGFVKQSNGHIKIYSEPGHGTSVKLYLPQATADADVLLLEASL
ASMERGDETILIVEDDSLVREYVIAQIKRLGYTTLAASKADEALSLIDSPARIDLLFTDIIMPGGMNGRQLAIEALKRRP
NLKVLYTSGYTENAIVHHGRLDAGVLLLTKPYQSADLARMIRTALNT

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=30.1255230125523, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1788549, Length=244, Percent_Identity=31.1475409836066, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1790300, Length=248, Percent_Identity=29.0322580645161, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI48994928, Length=223, Percent_Identity=29.1479820627803, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI145693157, Length=268, Percent_Identity=26.4925373134328, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57916; Mature: 57916

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTPHGECLLWTPELIWVNAVSDVLISVAFFTIAFVLGYIVFRRRDFQFSYIFWAFALWV
CCCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SVCGLTRLIEVLTLWVPAYVLEAATKGFLAFMSVGIAAALMLLLPRVLTMPSRADLKLAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
AQLEEETRQRRTAEAMVKRFQEIEATEAQVRQAQKMEAIGQLTGGVAHDFNNILTVITGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
IEILAEAVKDRPQLVQITSLINSAAARGADLTKHLLAFARRQPLQPRSVDINGMVVDTAR
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHH
LLRRTLGEQIEIESMLAHDSAPAMIDPSQLSTAILNLALNARDAMPNGGKLTLETKNVLL
HHHHHCCCCEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHH
DDAYARMNPEVIPGNYVMIAVSDTGEGIPSNLLDKVFEPFFTTKDVGKGVGLGLSMVYGF
HHHHHHCCCCEECCCEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHH
VKQSNGHIKIYSEPGHGTSVKLYLPQATADADVLLLEASLASMERGDETILIVEDDSLVR
HHCCCCEEEEEECCCCCCEEEEEECCCCCCCCEEEEEHHHHHHCCCCCEEEEECCHHHHH
EYVIAQIKRLGYTTLAASKADEALSLIDSPARIDLLFTDIIMPGGMNGRQLAIEALKRRP
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCHHHHHHHHHCCC
NLKVLYTSGYTENAIVHHGRLDAGVLLLTKPYQSADLARMIRTALNT
CEEEEEECCCCCCCEEECCCCCCCEEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLTPHGECLLWTPELIWVNAVSDVLISVAFFTIAFVLGYIVFRRRDFQFSYIFWAFALWV
CCCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SVCGLTRLIEVLTLWVPAYVLEAATKGFLAFMSVGIAAALMLLLPRVLTMPSRADLKLAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
AQLEEETRQRRTAEAMVKRFQEIEATEAQVRQAQKMEAIGQLTGGVAHDFNNILTVITGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
IEILAEAVKDRPQLVQITSLINSAAARGADLTKHLLAFARRQPLQPRSVDINGMVVDTAR
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHH
LLRRTLGEQIEIESMLAHDSAPAMIDPSQLSTAILNLALNARDAMPNGGKLTLETKNVLL
HHHHHCCCCEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHH
DDAYARMNPEVIPGNYVMIAVSDTGEGIPSNLLDKVFEPFFTTKDVGKGVGLGLSMVYGF
HHHHHHCCCCEECCCEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHH
VKQSNGHIKIYSEPGHGTSVKLYLPQATADADVLLLEASLASMERGDETILIVEDDSLVR
HHCCCCEEEEEECCCCCCEEEEEECCCCCCCCEEEEEHHHHHHCCCCCEEEEECCHHHHH
EYVIAQIKRLGYTTLAASKADEALSLIDSPARIDLLFTDIIMPGGMNGRQLAIEALKRRP
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCHHHHHHHHHCCC
NLKVLYTSGYTENAIVHHGRLDAGVLLLTKPYQSADLARMIRTALNT
CEEEEEECCCCCCCEEECCCCCCCEEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA