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The map label for this gene is 146343835

Identifier: 146343835

GI number: 146343835

Start: 7399268

End: 7400572

Strand: Direct

Name: 146343835

Synonym: BRADO7085

Alternate gene names: NA

Gene position: 7399268-7400572 (Clockwise)

Preceding gene: 146343834

Following gene: 146343836

Centisome position: 99.23

GC content: 68.97

Gene sequence:

>1305_bases
ATGACCACGCTTTCCTCGATCGTCGCGCGCGGTGTCGCGCTGGTTGGCAATGCGGCGCTGCAGTGGCGCAAATTGCAGGG
GGACACGCCGCAGCCGGCGTGGGGCGCGGCGCCGCAGATCCCGGTGGCGAAGCCGCAGGGGATGCTGCCGACCTTGAAGA
TGCCGACGGCGCGCGGCTGGCGCGACGGCGAAAAGCCGGTGGCGGCGCCGGGGCTGAAGGTGAATGCGTTCGCGACCGGG
CTCGACCATCCGCGCTGGATCTATGTCATGCCGGACAGGTCGGTGCTGATCGCGGAGGCGACGCAGGTGCCGAGCCCGGT
GCGCAACATGTTCGGCTACGCGATGCAGGCGACGATGCGCCGCGCCGCCGCGCTCGGTGTCAGCGCCAACCGCATCACGC
GGCTGGTCGATGCCGACGGCGACGGCACCGCCGAGCGGCGCAACGCGTTCATGGAGAATCTCAGCCAGCCGTTCGGCATG
GCGCTGGTCGGCGATACCTTCTATGTCGGCAATACCGACGGCATTGTTGCTTTCCCTTATAGCCCGGGCGCCGAGCGCAT
CAGCGCTGCCGGCAAGCGGCTGACGACGTTCAAACCGGGCGGGCACTGGACGCGCAGCCTGCTGGTCAGCCCCGATGGCA
CCAAGCTCTATGCGGGCGTCGGCTCGCTGAGCAACATCGCCGAGCAGGGTTTTGCGGTCGAGGAAGGCCGCGCCTGCATC
TATGAGCTGGACATCGCGAGCGGGGCGAGCCGCATCTTCGCGGCCGGACTGCGCAACGCGGTGGGGCTGGCGTTCGAGCC
GACCACGAAGGTGCTGTGGACCGTGGTCAACGAGCGCGACGGGCTCGGCGACGAGACGCCGCCGGACTATCTCACATCCG
TGCGCGATGGCGGCTTCTATGGCTGGCCCTATTGCTACTGGGGCAAGACGGTCGACGACCGCGTGCCGCAGGATTCCAAA
CTGGTCGCGACCGCGCTGACGCCGGACTATGCGCTCGGCGGCCACACCGCCTCGCTCGGCCTGTGCTGGCTGCCGGCGGG
CACCCTCCCCGGCTTCCCCGATGGCATGGTGATCGGCCAGCACGGCTCGTGGAATCGCAGCAAGCTGTCCGGCTACAAGG
TCGTGTTCATCCCGTTCGAGAACGGCAAGCCGTCGGGACCGGCGCGCGACATCCTGTCCGGCTTCCTCGCGCCCGATGAG
AGCTTTTCTTATGGCCGCCCGGTCGGCGTGACGCTGGGGCCGGACGGCTCGCTGCTGGTCGCCGACGACGTCGGCAACTG
CATCTGGCGGGTGACGGGCGCTTGA

Upstream 100 bases:

>100_bases
TTGTCACGTTGGGCGTGGTAGATCATAACGACCTTGCCGTTCCGCCATCGCCCGATGGCCGCTCACCACATCCGTCGATC
CAGCCCGAAACAGGACTCCC

Downstream 100 bases:

>100_bases
CCCGGGCGTGACGGAACCGGGCTCGCCTCGGGCCGTTGTCGCGGGGACAATGGAACAGTCCCAGGAGAGTCACATGGCCG
ACAACGTCAATCCGAACCAG

Product: L-sorbosone dehydrogenase

Products: NA

Alternate protein names: SNDH [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MTTLSSIVARGVALVGNAALQWRKLQGDTPQPAWGAAPQIPVAKPQGMLPTLKMPTARGWRDGEKPVAAPGLKVNAFATG
LDHPRWIYVMPDRSVLIAEATQVPSPVRNMFGYAMQATMRRAAALGVSANRITRLVDADGDGTAERRNAFMENLSQPFGM
ALVGDTFYVGNTDGIVAFPYSPGAERISAAGKRLTTFKPGGHWTRSLLVSPDGTKLYAGVGSLSNIAEQGFAVEEGRACI
YELDIASGASRIFAAGLRNAVGLAFEPTTKVLWTVVNERDGLGDETPPDYLTSVRDGGFYGWPYCYWGKTVDDRVPQDSK
LVATALTPDYALGGHTASLGLCWLPAGTLPGFPDGMVIGQHGSWNRSKLSGYKVVFIPFENGKPSGPARDILSGFLAPDE
SFSYGRPVGVTLGPDGSLLVADDVGNCIWRVTGA

Sequences:

>Translated_434_residues
MTTLSSIVARGVALVGNAALQWRKLQGDTPQPAWGAAPQIPVAKPQGMLPTLKMPTARGWRDGEKPVAAPGLKVNAFATG
LDHPRWIYVMPDRSVLIAEATQVPSPVRNMFGYAMQATMRRAAALGVSANRITRLVDADGDGTAERRNAFMENLSQPFGM
ALVGDTFYVGNTDGIVAFPYSPGAERISAAGKRLTTFKPGGHWTRSLLVSPDGTKLYAGVGSLSNIAEQGFAVEEGRACI
YELDIASGASRIFAAGLRNAVGLAFEPTTKVLWTVVNERDGLGDETPPDYLTSVRDGGFYGWPYCYWGKTVDDRVPQDSK
LVATALTPDYALGGHTASLGLCWLPAGTLPGFPDGMVIGQHGSWNRSKLSGYKVVFIPFENGKPSGPARDILSGFLAPDE
SFSYGRPVGVTLGPDGSLLVADDVGNCIWRVTGA
>Mature_433_residues
TTLSSIVARGVALVGNAALQWRKLQGDTPQPAWGAAPQIPVAKPQGMLPTLKMPTARGWRDGEKPVAAPGLKVNAFATGL
DHPRWIYVMPDRSVLIAEATQVPSPVRNMFGYAMQATMRRAAALGVSANRITRLVDADGDGTAERRNAFMENLSQPFGMA
LVGDTFYVGNTDGIVAFPYSPGAERISAAGKRLTTFKPGGHWTRSLLVSPDGTKLYAGVGSLSNIAEQGFAVEEGRACIY
ELDIASGASRIFAAGLRNAVGLAFEPTTKVLWTVVNERDGLGDETPPDYLTSVRDGGFYGWPYCYWGKTVDDRVPQDSKL
VATALTPDYALGGHTASLGLCWLPAGTLPGFPDGMVIGQHGSWNRSKLSGYKVVFIPFENGKPSGPARDILSGFLAPDES
FSYGRPVGVTLGPDGSLLVADDVGNCIWRVTGA

Specific function: Converts L-sorbosone into 2-keto-L-gulonic acid (2KGA) [H]

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.burgdorferi BB024 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 46152; Mature: 46021

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLSSIVARGVALVGNAALQWRKLQGDTPQPAWGAAPQIPVAKPQGMLPTLKMPTARGW
CCCHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
RDGEKPVAAPGLKVNAFATGLDHPRWIYVMPDRSVLIAEATQVPSPVRNMFGYAMQATMR
CCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHH
RAAALGVSANRITRLVDADGDGTAERRNAFMENLSQPFGMALVGDTFYVGNTDGIVAFPY
HHHHCCCCHHHEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCEEEECCCCCEEEECC
SPGAERISAAGKRLTTFKPGGHWTRSLLVSPDGTKLYAGVGSLSNIAEQGFAVEEGRACI
CCCHHHHHHCCCEEEEECCCCCEEEEEEECCCCCEEEECCCHHHHHHHCCCEEECCCEEE
YELDIASGASRIFAAGLRNAVGLAFEPTTKVLWTVVNERDGLGDETPPDYLTSVRDGGFY
EEEECCCCHHHHHHHHHHHHCCEEECCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCEE
GWPYCYWGKTVDDRVPQDSKLVATALTPDYALGGHTASLGLCWLPAGTLPGFPDGMVIGQ
CCCEEECCCCHHHCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEECC
HGSWNRSKLSGYKVVFIPFENGKPSGPARDILSGFLAPDESFSYGRPVGVTLGPDGSLLV
CCCCCCHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEE
ADDVGNCIWRVTGA
ECCCCCEEEEEECC
>Mature Secondary Structure 
TTLSSIVARGVALVGNAALQWRKLQGDTPQPAWGAAPQIPVAKPQGMLPTLKMPTARGW
CCHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
RDGEKPVAAPGLKVNAFATGLDHPRWIYVMPDRSVLIAEATQVPSPVRNMFGYAMQATMR
CCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHH
RAAALGVSANRITRLVDADGDGTAERRNAFMENLSQPFGMALVGDTFYVGNTDGIVAFPY
HHHHCCCCHHHEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCEEEECCCCCEEEECC
SPGAERISAAGKRLTTFKPGGHWTRSLLVSPDGTKLYAGVGSLSNIAEQGFAVEEGRACI
CCCHHHHHHCCCEEEEECCCCCEEEEEEECCCCCEEEECCCHHHHHHHCCCEEECCCEEE
YELDIASGASRIFAAGLRNAVGLAFEPTTKVLWTVVNERDGLGDETPPDYLTSVRDGGFY
EEEECCCCHHHHHHHHHHHHCCEEECCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCEE
GWPYCYWGKTVDDRVPQDSKLVATALTPDYALGGHTASLGLCWLPAGTLPGFPDGMVIGQ
CCCEEECCCCHHHCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEECC
HGSWNRSKLSGYKVVFIPFENGKPSGPARDILSGFLAPDESFSYGRPVGVTLGPDGSLLV
CCCCCCHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEE
ADDVGNCIWRVTGA
ECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7574579 [H]