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The map label for this gene is rfbC [H]

Identifier: 146343780

GI number: 146343780

Start: 7330892

End: 7331446

Strand: Reverse

Name: rfbC [H]

Synonym: BRADO7027

Alternate gene names: 146343780

Gene position: 7331446-7330892 (Counterclockwise)

Preceding gene: 146343783

Following gene: 146343779

Centisome position: 98.32

GC content: 63.42

Gene sequence:

>555_bases
ATGAACGTCATCAAAACCGACTTGCCTGAAGTTATCATTCTCGAGCCGAAGCTGTTCGGTGACCACCGAGGTTTCTTCCT
GGAGACGTTCCAGGCCGCCCGCTACCGCGAGCTCGGTATCAACGGGCCGTTCGTGCAGGACAACATGTCCCGCTCGTCCT
ATGGCGTGCTGCGCGGGCTGCATCTGCAGAACCCGAACACGCAAGGCAAGCTGGTCAGCGCGATGCGCGGCCGGGTGCTG
GACGTGGCGGTCGATGTGCGCGTCGGCAGCCCGAATTTCGGCAAGCATGTCGCCGTGGAACTGTCGGAGGAGAACCGCCG
CCAGCTCTGGGTTCCCCGCGGCTTCGCCCACGGCTTCGTCGTGCTCTCGGAGAGCGCGGATTTCTTCTACAAATGCGACG
ACTATTACAGTCCCAAGGACGAGATGTCGGTGCGCTGGAACGATCCGGCGATCGGCATCGACTGGGGCGTGCCAGAGCCG
AAGCTGTCGCCCAAGGACGCCGAGGCGCCGCTGCTGGCGGAGGCCCGGAATCTTCCCGTGTACGGGCAGATCTGA

Upstream 100 bases:

>100_bases
CAGCGAATAATTGTTATGTTAACAGATAGCGTGCGTTGCACAAGTTGGATAAAGGGATACAGTAAATTGTAGAAGCGCAA
TCCATTTAGCAGACCATTCG

Downstream 100 bases:

>100_bases
TGCGCATTCTGATCACGGGCACCAGCGGACAGGTCGGCGGCGCGCTGCGCAGGCTGCTGCCGGCCGGTGGAACCGATGAG
CTGATCTGCCCGCCGCGCGC

Product: dTDP-4,deoxyrhamnose 3,5 epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MNVIKTDLPEVIILEPKLFGDHRGFFLETFQAARYRELGINGPFVQDNMSRSSYGVLRGLHLQNPNTQGKLVSAMRGRVL
DVAVDVRVGSPNFGKHVAVELSEENRRQLWVPRGFAHGFVVLSESADFFYKCDDYYSPKDEMSVRWNDPAIGIDWGVPEP
KLSPKDAEAPLLAEARNLPVYGQI

Sequences:

>Translated_184_residues
MNVIKTDLPEVIILEPKLFGDHRGFFLETFQAARYRELGINGPFVQDNMSRSSYGVLRGLHLQNPNTQGKLVSAMRGRVL
DVAVDVRVGSPNFGKHVAVELSEENRRQLWVPRGFAHGFVVLSESADFFYKCDDYYSPKDEMSVRWNDPAIGIDWGVPEP
KLSPKDAEAPLLAEARNLPVYGQI
>Mature_184_residues
MNVIKTDLPEVIILEPKLFGDHRGFFLETFQAARYRELGINGPFVQDNMSRSSYGVLRGLHLQNPNTQGKLVSAMRGRVL
DVAVDVRVGSPNFGKHVAVELSEENRRQLWVPRGFAHGFVVLSESADFFYKCDDYYSPKDEMSVRWNDPAIGIDWGVPEP
KLSPKDAEAPLLAEARNLPVYGQI

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=185, Percent_Identity=51.8918918918919, Blast_Score=174, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17550412, Length=152, Percent_Identity=44.7368421052632, Blast_Score=130, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20719; Mature: 20719

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIKTDLPEVIILEPKLFGDHRGFFLETFQAARYRELGINGPFVQDNMSRSSYGVLRGL
CCCCCCCCCCEEEECCEECCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHEEEE
HLQNPNTQGKLVSAMRGRVLDVAVDVRVGSPNFGKHVAVELSEENRRQLWVPRGFAHGFV
EECCCCCCHHHHHHHCCEEEEEEEEEEECCCCCCCEEEEEECCCCCEEEECCCCCCCEEE
VLSESADFFYKCDDYYSPKDEMSVRWNDPAIGIDWGVPEPKLSPKDAEAPLLAEARNLPV
EEECCCCEEEEECCCCCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCCCHHHCCCCE
YGQI
EECC
>Mature Secondary Structure
MNVIKTDLPEVIILEPKLFGDHRGFFLETFQAARYRELGINGPFVQDNMSRSSYGVLRGL
CCCCCCCCCCEEEECCEECCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHEEEE
HLQNPNTQGKLVSAMRGRVLDVAVDVRVGSPNFGKHVAVELSEENRRQLWVPRGFAHGFV
EECCCCCCHHHHHHHCCEEEEEEEEEEECCCCCCCEEEEEECCCCCEEEECCCCCCCEEE
VLSESADFFYKCDDYYSPKDEMSVRWNDPAIGIDWGVPEPKLSPKDAEAPLLAEARNLPV
EEECCCCEEEEECCCCCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCCCHHHCCCCE
YGQI
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609; 10802738 [H]