The gene/protein map for NC_009445 is currently unavailable.
Definition Bradyrhizobium sp. ORS278 chromosome, complete genome.
Accession NC_009445
Length 7,456,587

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The map label for this gene is gno [H]

Identifier: 146343387

GI number: 146343387

Start: 6867596

End: 6868369

Strand: Reverse

Name: gno [H]

Synonym: BRADO6616

Alternate gene names: 146343387

Gene position: 6868369-6867596 (Counterclockwise)

Preceding gene: 146343388

Following gene: 146343386

Centisome position: 92.11

GC content: 64.47

Gene sequence:

>774_bases
ATGTATCTGGAAAAATTCAAGCTGAACGGCAAGACGGCGCTGATCACCGGCGGCGCGCAGGGCATCGGCCTTGCCTGTGT
CGAGGCGCTGGCGGAGGCGGGCGCGCATGTGGTGATCGCCGATCGCGACGCCAAGGCGGCGGCGGACGCGCAGGTCGCGA
TGAAGGCTAAGGGCTTCACCACCGAGACCGCGCTGATGGACGTCACCGATTCGGCGCAGGTGACGCAGATCGCCGACGAT
CTCGTCGCACGGCACGGCAAGGTCGACATCCTCGTCAACAATGCCGGCATCGCCCGCAGCGAGACACCGGCCGAGACGGT
CACCGACGAGCACTGGCTCAATGTGCTCGACGTCAATCTCAACGGCACCTTCTGGTGCTGCCGCGCCTTCGGCAAGCATA
TGCTGGCGGCCAAGAGCGGCACCATCGTCAACATCGGTTCGATGTCGGGCTTCATCGTCAACAAGCCGCAGGAGCAGTCG
TTCTACAATGCCTCCAAGGCCGCGGTGCACCATCTGACCAAGTCGCTGGCCGCCGAATGGGGCGCGCGCGGCATCCGCGT
CAACGCGGTCGCGCCGACCTATATCGAAACGCCGCTGAATGCCTTCGTGAAGAGCAACCCGCGGATGTACGACGCCTGGA
TCGGCGGAACCCCGATGGCGCGGATGGGGCAGGTCGAGGAGATCGCCTCCGTCGTGCTGTTCCTGGCTTCGGAGGCGGCA
AGTTTGATGACCGGCAGCGTCGTCGTTGTCGATGGCGGCTACACTTGCTGGTAA

Upstream 100 bases:

>100_bases
AGCCGAACCGCATCTACCGCTTCGACGAGAGCGGCCATTCCATCTTCACATGAGAGGTGACGTCCCCTTCGGGCGTCAAC
GACAACCACGGACGACGACG

Downstream 100 bases:

>100_bases
GCTCGCGTCAAAATTGACGGGAGCGAAACATGGGCCAGGCTTTTATCGGTGTCGATGTCGGCACGTCCAGCACGCGCGCC
GGAATTTTCGACGAGAACGG

Product: putative oxidoreductase glucose/ribitol oxidoreductase

Products: NA

Alternate protein names: 5-keto-D-gluconate 5-reductase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MYLEKFKLNGKTALITGGAQGIGLACVEALAEAGAHVVIADRDAKAAADAQVAMKAKGFTTETALMDVTDSAQVTQIADD
LVARHGKVDILVNNAGIARSETPAETVTDEHWLNVLDVNLNGTFWCCRAFGKHMLAAKSGTIVNIGSMSGFIVNKPQEQS
FYNASKAAVHHLTKSLAAEWGARGIRVNAVAPTYIETPLNAFVKSNPRMYDAWIGGTPMARMGQVEEIASVVLFLASEAA
SLMTGSVVVVDGGYTCW

Sequences:

>Translated_257_residues
MYLEKFKLNGKTALITGGAQGIGLACVEALAEAGAHVVIADRDAKAAADAQVAMKAKGFTTETALMDVTDSAQVTQIADD
LVARHGKVDILVNNAGIARSETPAETVTDEHWLNVLDVNLNGTFWCCRAFGKHMLAAKSGTIVNIGSMSGFIVNKPQEQS
FYNASKAAVHHLTKSLAAEWGARGIRVNAVAPTYIETPLNAFVKSNPRMYDAWIGGTPMARMGQVEEIASVVLFLASEAA
SLMTGSVVVVDGGYTCW
>Mature_257_residues
MYLEKFKLNGKTALITGGAQGIGLACVEALAEAGAHVVIADRDAKAAADAQVAMKAKGFTTETALMDVTDSAQVTQIADD
LVARHGKVDILVNNAGIARSETPAETVTDEHWLNVLDVNLNGTFWCCRAFGKHMLAAKSGTIVNIGSMSGFIVNKPQEQS
FYNASKAAVHHLTKSLAAEWGARGIRVNAVAPTYIETPLNAFVKSNPRMYDAWIGGTPMARMGQVEEIASVVLFLASEAA
SLMTGSVVVVDGGYTCW

Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=265, Percent_Identity=35.8490566037736, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=32.9268292682927, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=35.4581673306773, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI4503301, Length=256, Percent_Identity=33.59375, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=32.9268292682927, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=32.0158102766798, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=32.03125, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI59889578, Length=239, Percent_Identity=32.6359832635983, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=27.7551020408163, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=28.8, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI31542939, Length=211, Percent_Identity=31.7535545023697, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=32.5581395348837, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4504505, Length=197, Percent_Identity=32.48730964467, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=30.9782608695652, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI33667109, Length=201, Percent_Identity=27.8606965174129, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI109715829, Length=243, Percent_Identity=28.3950617283951, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI20149619, Length=202, Percent_Identity=31.6831683168317, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI224922801, Length=176, Percent_Identity=32.3863636363636, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI157739938, Length=195, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI226371731, Length=219, Percent_Identity=28.310502283105, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI83715985, Length=256, Percent_Identity=29.6875, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI210032110, Length=198, Percent_Identity=24.7474747474747, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI4557649, Length=205, Percent_Identity=28.2926829268293, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI142976729, Length=203, Percent_Identity=28.0788177339901, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=36.6533864541833, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=35.6862745098039, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=34, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=32.295719844358, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=35.1020408163265, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=33.7301587301587, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=31.9066147859922, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=33.0645161290323, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789378, Length=255, Percent_Identity=28.6274509803922, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1789057, Length=263, Percent_Identity=27.7566539923954, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=28.3333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787526, Length=208, Percent_Identity=26.9230769230769, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=36.8421052631579, Blast_Score=136, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI25147288, Length=255, Percent_Identity=38.4313725490196, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=30.5220883534137, Blast_Score=120, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=31.7460317460317, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=30.7116104868914, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=30.188679245283, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=34.3511450381679, Blast_Score=107, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=31.4393939393939, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=28.8537549407115, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=33.5907335907336, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=29.3233082706767, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=31.1284046692607, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=28.9473684210526, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=29.811320754717, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=30.9236947791165, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=28.968253968254, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=27.5092936802974, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=28.6792452830189, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=32.156862745098, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=28.1368821292776, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17565030, Length=267, Percent_Identity=29.5880149812734, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17561272, Length=262, Percent_Identity=33.206106870229, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=27.2727272727273, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=27.5471698113208, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=27.9245283018868, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=27.5471698113208, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=27.4809160305344, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI193203117, Length=199, Percent_Identity=30.6532663316583, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI193203115, Length=203, Percent_Identity=30.0492610837438, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17567345, Length=215, Percent_Identity=28.8372093023256, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=201, Percent_Identity=27.8606965174129, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=203, Percent_Identity=29.5566502463054, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=29.6, Blast_Score=89, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6322861, Length=253, Percent_Identity=27.6679841897233, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322067, Length=183, Percent_Identity=32.7868852459016, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=30.6122448979592, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322227, Length=203, Percent_Identity=27.0935960591133, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320089, Length=200, Percent_Identity=29, Blast_Score=62, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=38, Blast_Score=130, Evalue=6e-31,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=30.9236947791165, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=33.8582677165354, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=32.8185328185328, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=31.2252964426877, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24643142, Length=255, Percent_Identity=31.7647058823529, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24644337, Length=256, Percent_Identity=32.421875, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=29.9212598425197, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358495, Length=204, Percent_Identity=31.8627450980392, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI18859837, Length=198, Percent_Identity=31.8181818181818, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24581726, Length=214, Percent_Identity=29.9065420560748, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24584752, Length=206, Percent_Identity=31.0679611650485, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281364892, Length=175, Percent_Identity=32.5714285714286, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574402, Length=198, Percent_Identity=28.2828282828283, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584744, Length=198, Percent_Identity=28.2828282828283, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356301, Length=217, Percent_Identity=29.9539170506912, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24649181, Length=202, Percent_Identity=26.2376237623762, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24648693, Length=249, Percent_Identity=27.710843373494, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21355889, Length=249, Percent_Identity=27.710843373494, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI281364494, Length=225, Percent_Identity=31.1111111111111, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI116007236, Length=234, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24584748, Length=203, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI161076933, Length=203, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21357673, Length=198, Percent_Identity=28.7878787878788, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24665243, Length=200, Percent_Identity=31.5, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.69 [H]

Molecular weight: Translated: 27219; Mature: 27219

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MYLEKFKLNGKTALITGGAQGIGLACVEALAEAGAHVVIADRDAKAAADAQVAMKAKGFT
CCCCEEEECCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHCCHHEEEEECCCC
TETALMDVTDSAQVTQIADDLVARHGKVDILVNNAGIARSETPAETVTDEHWLNVLDVNL
CHHEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHCCCCCCEEEEEECC
NGTFWCCRAFGKHMLAAKSGTIVNIGSMSGFIVNKPQEQSFYNASKAAVHHLTKSLAAEW
CCCCHHHHHHHHHHEEECCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
GARGIRVNAVAPTYIETPLNAFVKSNPRMYDAWIGGTPMARMGQVEEIASVVLFLASEAA
CCCCEEEEEECCHHHHCCHHHHHCCCCEEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHH
SLMTGSVVVVDGGYTCW
HHHCCCEEEECCCEECC
>Mature Secondary Structure
MYLEKFKLNGKTALITGGAQGIGLACVEALAEAGAHVVIADRDAKAAADAQVAMKAKGFT
CCCCEEEECCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHCCHHEEEEECCCC
TETALMDVTDSAQVTQIADDLVARHGKVDILVNNAGIARSETPAETVTDEHWLNVLDVNL
CHHEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHCCCCCCEEEEEECC
NGTFWCCRAFGKHMLAAKSGTIVNIGSMSGFIVNKPQEQSFYNASKAAVHHLTKSLAAEW
CCCCHHHHHHHHHHEEECCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
GARGIRVNAVAPTYIETPLNAFVKSNPRMYDAWIGGTPMARMGQVEEIASVVLFLASEAA
CCCCEEEEEECCHHHHCCHHHHHCCCCEEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHH
SLMTGSVVVVDGGYTCW
HHHCCCEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751271 [H]