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The map label for this gene is ubiA [H]

Identifier: 146342921

GI number: 146342921

Start: 6329608

End: 6330540

Strand: Reverse

Name: ubiA [H]

Synonym: BRADO6102

Alternate gene names: 146342921

Gene position: 6330540-6329608 (Counterclockwise)

Preceding gene: 146342922

Following gene: 146342919

Centisome position: 84.9

GC content: 67.52

Gene sequence:

>933_bases
ATGAGCGACAGCGCCGTCCGCGTTGCTGACGCGACCGGCAATTGGGTCGACACGCTGGCGCCGGTCTGGAGCCGGCCCTA
TCTGCGGCTCGCCCGCTACGATCGCCCGATCGGCTCCTGGCTGCTGCTGATGCCCTGCTGGTGGTCGGCCGCACTGGCCT
CCGGCATCTCCGGCGATCTGTCGATGCTTCCCCTCTGGGTCGGCCTGTATTTTGTCGGTGCCTTCGCGATGCGCGGCGCC
GGCTGCACCTGGAACGACATCACCGACCGCGATCTCGACGCCCAGGTCGAGCGCACCCGGTCGCGGCCGATCCCGGCCGG
ACAGGTTGGGGTGAAGCGGGCGCTCGCCTTCCTGGTGGCGCAGGCTCTGATCGGCCTCGCCGTGCTGCTGCAGTTCAACC
GGTTTGCGATTCTGACCGGCATCGCGTCGCTGCTGATCGTCGCGATCTACCCTTTCATGAAGCGCATCACCTGGTGGCCG
CAGACGGTGCTGGGACTCGCCTTCTCATGGGGCGCGCTGATGGGCTTTGCCGTCGCGTTCGGGCGCCTCGATGCCACCGC
GCTGCTGCTCTATGCCGGCTCGATCTGCTGGGTCATCGCCTATGATACGATCTACGCGCACCAGGATGCGGAGGACGACG
CGCTGATCGGCATCAAGTCGACGGCGCGGCTGTTTGCCGAGCGCACGCATCTGGCGCTGGTGGTGTTCTATTCGCTCGCG
GTCGTGCTGATCGGAGCAGCCTTCGCCACCGCTCATGTGCGCGTCGCGGCGTGGCTCGGCCTCGCCTGCTTCGCCGCGCA
TCTCGCCTGGCAGGTTCGCCGGCTCGACACTGCGGATCCCGCGCTGTGCCTGCGCGTCTTCAAGTCGAACCGCGACGCAG
GATTGCTGCTGTTCGCCGCTCTCCTGATCGATGCCGTGTTGCGCGCGAGCTGA

Upstream 100 bases:

>100_bases
TCAGCGACGTGCTCGGCACGTCGGCCGCACTGCCGGAAGCCAACACGGCGAAGAAGGGCGGCTCGGCGTTCGATACTCTC
ACCGGCAACGTTCTGACACG

Downstream 100 bases:

>100_bases
TCAGCTCCGCGCGATGATCTCGCGCTCGCCGCGATGGACCGGGGCCGGATTGAGCAGGTGACCGACACGGCGCCGCATCA
GGAAACGTGGACGGCGTGAG

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSDSAVRVADATGNWVDTLAPVWSRPYLRLARYDRPIGSWLLLMPCWWSAALASGISGDLSMLPLWVGLYFVGAFAMRGA
GCTWNDITDRDLDAQVERTRSRPIPAGQVGVKRALAFLVAQALIGLAVLLQFNRFAILTGIASLLIVAIYPFMKRITWWP
QTVLGLAFSWGALMGFAVAFGRLDATALLLYAGSICWVIAYDTIYAHQDAEDDALIGIKSTARLFAERTHLALVVFYSLA
VVLIGAAFATAHVRVAAWLGLACFAAHLAWQVRRLDTADPALCLRVFKSNRDAGLLLFAALLIDAVLRAS

Sequences:

>Translated_310_residues
MSDSAVRVADATGNWVDTLAPVWSRPYLRLARYDRPIGSWLLLMPCWWSAALASGISGDLSMLPLWVGLYFVGAFAMRGA
GCTWNDITDRDLDAQVERTRSRPIPAGQVGVKRALAFLVAQALIGLAVLLQFNRFAILTGIASLLIVAIYPFMKRITWWP
QTVLGLAFSWGALMGFAVAFGRLDATALLLYAGSICWVIAYDTIYAHQDAEDDALIGIKSTARLFAERTHLALVVFYSLA
VVLIGAAFATAHVRVAAWLGLACFAAHLAWQVRRLDTADPALCLRVFKSNRDAGLLLFAALLIDAVLRAS
>Mature_309_residues
SDSAVRVADATGNWVDTLAPVWSRPYLRLARYDRPIGSWLLLMPCWWSAALASGISGDLSMLPLWVGLYFVGAFAMRGAG
CTWNDITDRDLDAQVERTRSRPIPAGQVGVKRALAFLVAQALIGLAVLLQFNRFAILTGIASLLIVAIYPFMKRITWWPQ
TVLGLAFSWGALMGFAVAFGRLDATALLLYAGSICWVIAYDTIYAHQDAEDDALIGIKSTARLFAERTHLALVVFYSLAV
VLIGAAFATAHVRVAAWLGLACFAAHLAWQVRRLDTADPALCLRVFKSNRDAGLLLFAALLIDAVLRAS

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=294, Percent_Identity=43.5374149659864, Blast_Score=220, Evalue=1e-57,
Organism=Escherichia coli, GI1790473, Length=275, Percent_Identity=36, Blast_Score=149, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17553718, Length=285, Percent_Identity=40.7017543859649, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI32565247, Length=286, Percent_Identity=38.1118881118881, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17553720, Length=352, Percent_Identity=31.5340909090909, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI32565245, Length=141, Percent_Identity=45.3900709219858, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI32565243, Length=140, Percent_Identity=45, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6324370, Length=303, Percent_Identity=39.9339933993399, Blast_Score=199, Evalue=4e-52,
Organism=Drosophila melanogaster, GI21355567, Length=289, Percent_Identity=45.6747404844291, Blast_Score=243, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 33818; Mature: 33687

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSAVRVADATGNWVDTLAPVWSRPYLRLARYDRPIGSWLLLMPCWWSAALASGISGDL
CCCCCEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCH
SMLPLWVGLYFVGAFAMRGAGCTWNDITDRDLDAQVERTRSRPIPAGQVGVKRALAFLVA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
QALIGLAVLLQFNRFAILTGIASLLIVAIYPFMKRITWWPQTVLGLAFSWGALMGFAVAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRLDATALLLYAGSICWVIAYDTIYAHQDAEDDALIGIKSTARLFAERTHLALVVFYSLA
HHHHHHHHHHHHCCHHEEEEHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
VVLIGAAFATAHVRVAAWLGLACFAAHLAWQVRRLDTADPALCLRVFKSNRDAGLLLFAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHH
LLIDAVLRAS
HHHHHHHHCC
>Mature Secondary Structure 
SDSAVRVADATGNWVDTLAPVWSRPYLRLARYDRPIGSWLLLMPCWWSAALASGISGDL
CCCCEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCH
SMLPLWVGLYFVGAFAMRGAGCTWNDITDRDLDAQVERTRSRPIPAGQVGVKRALAFLVA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
QALIGLAVLLQFNRFAILTGIASLLIVAIYPFMKRITWWPQTVLGLAFSWGALMGFAVAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRLDATALLLYAGSICWVIAYDTIYAHQDAEDDALIGIKSTARLFAERTHLALVVFYSLA
HHHHHHHHHHHHCCHHEEEEHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
VVLIGAAFATAHVRVAAWLGLACFAAHLAWQVRRLDTADPALCLRVFKSNRDAGLLLFAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHH
LLIDAVLRAS
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA