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The map label for this gene is moaE [H]

Identifier: 146342879

GI number: 146342879

Start: 6282655

End: 6283119

Strand: Direct

Name: moaE [H]

Synonym: BRADO6059

Alternate gene names: 146342879

Gene position: 6282655-6283119 (Clockwise)

Preceding gene: 146342878

Following gene: 146342880

Centisome position: 84.26

GC content: 66.02

Gene sequence:

>465_bases
ATGACCGCGATCGTTACCGTCCGCGTGCAGCACGAGGATTTCGACACCGCCGCCGAGATCGCAGCCCTCAGCCATGGCCG
CACCGACATCGGCGCCGTCGTCAGCTTCTCCGGACTGTGCCGCGGCAACGACCACGCCACCCCAATCTCGGCGCTGACGC
TCGAGCATTATCCGGGCATGGCGGAAGCCGAGATCATGCGTCATGCCGAGCAGGCAATGGCGCGCTGGCCGCTGCAGGGC
CTCACTGTCATCCATCGTTTCGGCCGCATCACGCCGGGCGAGAACATCGTGCTGGTGGTGACCGCATCCAGCCACCGCCA
GGCGGCGTTCGAGGCGGCCGAGTTCCTGATGGATTATCTCAAGACCAACGCGCCGTTCTGGAAGCGCGAGGAAACCAATG
ATGGCGGCAGCTGGGTCGAGGCCAAGAGCCACGACGATGCCGCCGCGGCGCGCTGGACGAAGTGA

Upstream 100 bases:

>100_bases
CAGACCCACGTGCAGCCGGACACGGTGATCGCCGGCGCCCGCGAGATCGCGTTCTTCCCGCCGATGACCGGCGGCTGAGG
CGCGCCGGAACACAACCGCC

Downstream 100 bases:

>100_bases
TGGCGAAGACAGTCAAGACGGCCGCACCGCGCAAGACGCAAGCGCCCAAGCTGCCCAAGCTGCCCAAGGTCAACGCCGGC
GAGCTCGTCACGCTTCTCGA

Product: molybdenum cofactor biosynthesis protein E

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MTAIVTVRVQHEDFDTAAEIAALSHGRTDIGAVVSFSGLCRGNDHATPISALTLEHYPGMAEAEIMRHAEQAMARWPLQG
LTVIHRFGRITPGENIVLVVTASSHRQAAFEAAEFLMDYLKTNAPFWKREETNDGGSWVEAKSHDDAAAARWTK

Sequences:

>Translated_154_residues
MTAIVTVRVQHEDFDTAAEIAALSHGRTDIGAVVSFSGLCRGNDHATPISALTLEHYPGMAEAEIMRHAEQAMARWPLQG
LTVIHRFGRITPGENIVLVVTASSHRQAAFEAAEFLMDYLKTNAPFWKREETNDGGSWVEAKSHDDAAAARWTK
>Mature_153_residues
TAIVTVRVQHEDFDTAAEIAALSHGRTDIGAVVSFSGLCRGNDHATPISALTLEHYPGMAEAEIMRHAEQAMARWPLQGL
TVIHRFGRITPGENIVLVVTASSHRQAAFEAAEFLMDYLKTNAPFWKREETNDGGSWVEAKSHDDAAAARWTK

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=108, Percent_Identity=31.4814814814815, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1787003, Length=144, Percent_Identity=49.3055555555556, Blast_Score=144, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17509279, Length=112, Percent_Identity=32.1428571428571, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356259, Length=115, Percent_Identity=31.304347826087, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16929; Mature: 16798

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIVTVRVQHEDFDTAAEIAALSHGRTDIGAVVSFSGLCRGNDHATPISALTLEHYPGM
CCEEEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCHHEEECCCCCCC
AEAEIMRHAEQAMARWPLQGLTVIHRFGRITPGENIVLVVTASSHRQAAFEAAEFLMDYL
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
KTNAPFWKREETNDGGSWVEAKSHDDAAAARWTK
HCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
TAIVTVRVQHEDFDTAAEIAALSHGRTDIGAVVSFSGLCRGNDHATPISALTLEHYPGM
CEEEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCHHEEECCCCCCC
AEAEIMRHAEQAMARWPLQGLTVIHRFGRITPGENIVLVVTASSHRQAAFEAAEFLMDYL
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
KTNAPFWKREETNDGGSWVEAKSHDDAAAARWTK
HCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]