Click here to switch to the map view.

The map label for this gene is aroE [H]

Identifier: 146342784

GI number: 146342784

Start: 6182816

End: 6183682

Strand: Reverse

Name: aroE [H]

Synonym: BRADO5961

Alternate gene names: 146342784

Gene position: 6183682-6182816 (Counterclockwise)

Preceding gene: 146342785

Following gene: 146342783

Centisome position: 82.93

GC content: 69.09

Gene sequence:

>867_bases
GTGAGCTTGTCCGATGTCACGGCCATGACCGCCGCCGCCAAAATCCCCGCCGCGTGCCTGATCGGCTGGCCTGCCGCGCA
TTCGCGCTCGCCGCTCATCCATCATCATTGGCTGCACCAGCTCGGGATTTCCGGCGGCTACACGATCGAGGCCGTGCCGC
CCGAGGAGCTCGCGAACTTCGTGATGCATCTGCATCATCGCGGCTTCGTCGGCGCCAATGTCACGATTCCGCACAAGGAG
CGGGTGCTCGAATTGGCCGAGCCGGATGCGCGCGCGCGCGCCGTCGGCGCCGCCAACACGCTGTGGTACGAGCGCGGGGT
GTTGCGTGCGACCAACACCGACGTCGAAGGCTTCATCGGCAATCTCGACGCGGTGGCGCCGGGCTGGGATCGGACCAACG
AGGCGTTGGTGCTCGGCTCCGGAGGAGCGGCGCGAGCCGTCGTATTCGGGCTTCTGGAGCGCGGCATCGGGCGCGTCCAC
GTCATCAACCGCACCGCCGCCCGCGCGCAAGCCTTGGCCGATCAGTTCGGCAGCCGGGTCGTCGCAGAAGGCTGGGACCG
CGTCGGCGCGCTGCTGCCGGGCGCGGGTCTGTTCGTGAACACCACCGCGCTCGGCATGCACGGTCAGCCGCCGCTCGCGC
TTGATGTCGACCTGTTGTCGCCGCATGCCGTTGTGGCCGACATCGTCTACGTGCCGTTGGAGACGCAACTGCTCGGCGCC
GCGCGGGCGCGAGGCCTGCGCACGGCGGATGGGCTCGGCATGCTCCTGCATCAGGCCGTGCGCGGCTTCGAACTGTGGTT
CGGCCGGCGTCCGCAGGTCACCCCTGAGCTGAGGGCGCTGGTGGAAGCGGATCTCACAAAGGCTTGA

Upstream 100 bases:

>100_bases
CTGCATCTCGGCCTCATCGCGGTGTGGGCCGGGGGCTGCGTCGCGCTGCTGATCGCCTTCGTCGCGGCGGTGGCGGCCGA
CCCCGAGCATTGACTCCGGC

Downstream 100 bases:

>100_bases
AGCCGGAATAAGTCTCAAAACAGAGCGTCTCACTCGTCATGCGTCCGCGCCCCGACTAAGTCACGCGGAGCTTTCGCCCA
AAGCCCGGAGCTTATGCATG

Product: shikimate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSLSDVTAMTAAAKIPAACLIGWPAAHSRSPLIHHHWLHQLGISGGYTIEAVPPEELANFVMHLHHRGFVGANVTIPHKE
RVLELAEPDARARAVGAANTLWYERGVLRATNTDVEGFIGNLDAVAPGWDRTNEALVLGSGGAARAVVFGLLERGIGRVH
VINRTAARAQALADQFGSRVVAEGWDRVGALLPGAGLFVNTTALGMHGQPPLALDVDLLSPHAVVADIVYVPLETQLLGA
ARARGLRTADGLGMLLHQAVRGFELWFGRRPQVTPELRALVEADLTKA

Sequences:

>Translated_288_residues
MSLSDVTAMTAAAKIPAACLIGWPAAHSRSPLIHHHWLHQLGISGGYTIEAVPPEELANFVMHLHHRGFVGANVTIPHKE
RVLELAEPDARARAVGAANTLWYERGVLRATNTDVEGFIGNLDAVAPGWDRTNEALVLGSGGAARAVVFGLLERGIGRVH
VINRTAARAQALADQFGSRVVAEGWDRVGALLPGAGLFVNTTALGMHGQPPLALDVDLLSPHAVVADIVYVPLETQLLGA
ARARGLRTADGLGMLLHQAVRGFELWFGRRPQVTPELRALVEADLTKA
>Mature_287_residues
SLSDVTAMTAAAKIPAACLIGWPAAHSRSPLIHHHWLHQLGISGGYTIEAVPPEELANFVMHLHHRGFVGANVTIPHKER
VLELAEPDARARAVGAANTLWYERGVLRATNTDVEGFIGNLDAVAPGWDRTNEALVLGSGGAARAVVFGLLERGIGRVHV
INRTAARAQALADQFGSRVVAEGWDRVGALLPGAGLFVNTTALGMHGQPPLALDVDLLSPHAVVADIVYVPLETQLLGAA
RARGLRTADGLGMLLHQAVRGFELWFGRRPQVTPELRALVEADLTKA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=271, Percent_Identity=35.7933579335793, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1787983, Length=279, Percent_Identity=31.8996415770609, Blast_Score=97, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6320332, Length=269, Percent_Identity=26.0223048327138, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30684; Mature: 30552

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSDVTAMTAAAKIPAACLIGWPAAHSRSPLIHHHWLHQLGISGGYTIEAVPPEELANF
CCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEECCHHHHHHH
VMHLHHRGFVGANVTIPHKERVLELAEPDARARAVGAANTLWYERGVLRATNTDVEGFIG
HHHHHHCCCCCCCEECCHHHHHHHHCCCCHHHHHHCCHHHHHHHCCEEEECCCCHHHHHC
NLDAVAPGWDRTNEALVLGSGGAARAVVFGLLERGIGRVHVINRTAARAQALADQFGSRV
CCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCH
VAEGWDRVGALLPGAGLFVNTTALGMHGQPPLALDVDLLSPHAVVADIVYVPLETQLLGA
HHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHEEECCHHHHHHH
ARARGLRTADGLGMLLHQAVRGFELWFGRRPQVTPELRALVEADLTKA
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLSDVTAMTAAAKIPAACLIGWPAAHSRSPLIHHHWLHQLGISGGYTIEAVPPEELANF
CCHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEECCHHHHHHH
VMHLHHRGFVGANVTIPHKERVLELAEPDARARAVGAANTLWYERGVLRATNTDVEGFIG
HHHHHHCCCCCCCEECCHHHHHHHHCCCCHHHHHHCCHHHHHHHCCEEEECCCCHHHHHC
NLDAVAPGWDRTNEALVLGSGGAARAVVFGLLERGIGRVHVINRTAARAQALADQFGSRV
CCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCH
VAEGWDRVGALLPGAGLFVNTTALGMHGQPPLALDVDLLSPHAVVADIVYVPLETQLLGA
HHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHEEECCHHHHHHH
ARARGLRTADGLGMLLHQAVRGFELWFGRRPQVTPELRALVEADLTKA
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA