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The map label for this gene is lolC [H]

Identifier: 146342763

GI number: 146342763

Start: 6153947

End: 6155173

Strand: Reverse

Name: lolC [H]

Synonym: BRADO5937

Alternate gene names: 146342763

Gene position: 6155173-6153947 (Counterclockwise)

Preceding gene: 146342764

Following gene: 146342762

Centisome position: 82.55

GC content: 67.48

Gene sequence:

>1227_bases
GTGAACCGCTGGCTGCCGTTCGAATGGGTCGCGGCGGTGCGCTTCCTGCGCGAGGGCCGGCTGCAGACCCTGTTCATCAT
CGGCGGCATCGCGATCGGCGTCGCCGTGATCGTGTTCATGTCGGCGATGCTCGCAGGGCTGGAAGCCAACTTCATCAAGC
GCGTGCTGACGTCGCAGCCGCAAATCCAGTTGCTGACGCCGGACCAGGTCGCGCGGCCGCTGCGCAACGGCAATCGCGTG
ATCGAGGACGCCACCGTGCAGCGGCCGAGCCAGCGCGTGATCTCGATCGACCAATGGCCGAAGATCCGCGCCCAGATGCT
GGCGATGCCGGAGATCACCGCGGTGTCGCCGACCATCTCGGGCTCGGCGCTCGCCATTCGCGGCGACGCCAGCCGCGCCG
TGACACTGTCCGGCATTGAGCCGGAGAGCTATTTCGCCATCGTGCGCGTGCCGGACTATATCGTTGCCGGCGAGCCGCGG
CTGAGCAGCGAGGACATCATCATCGGCATCGAGCTGGCCAAGGATCTCGGTGCCGTCGTCGGCGACAAGCTCAACGTCCA
GGCCGCTTCCGGCGCCAATCGCGTGCTGACCGTGACCGGCCTGGTCGACCTCGGCAACAAGGGCGTCAACCAGCGCGCCG
CCTACGTCGCGCTGCGCACCGCGCAGTCGCTGCTCGGCATGATCGGCGGCGTCACCACCATCGACATCACCGTGCAGGAC
ATCTACGCAGCGGAAGACATCGCGCAGCGCATCCAGGCCGCCAACCTCGTCAAGGCCGACAGCTGGATCAAGACCAATGC
GCAGTTCTTCGTGGCCGTGCGCGCGCAGGAGACTTCGAACACGCTGATCCGCGTATTCGTCGCAATGTCGGTCGCCTTCG
GCATCGCTGCCGTGCTCATCGTCTCCGTCATCCAGCGCTCGAAGGAGATCGGCATTCTCCGGGCGATGGGCACCTCGCGC
GGCCAGATCCTGCGCGTGTTCCTGCTGCAAGGCGGGCTGCTCGGCTTCATCGGCTCGCTGTTCGGCGCCGCGCTCGGCGC
CGGCGCGCTGATCTACTGGCATGCGGTGCAGCGCCAGGCGGATGGATCGGAGTTGTTCCCGCTCATTCTCGAGCGCCGCC
TGTTCGTCATCACGGCCCTGCTCGCGACGGTCACGGGATTGCTCGCGGCGACCGCGCCGGCGTTGCGCGCGGCCAAGCTC
GATCCGGTGGTGGCGATCCGTGGCTGA

Upstream 100 bases:

>100_bases
ACAGCCATGTCGAGATCGTCGATGGCCTGAGTGCCGGCGACATCGCGGTGCCCGCCAGCTCCGGCCTCGTCACTGGCCAG
CGCTTCCGTCCGGTGCTGCC

Downstream 100 bases:

>100_bases
GGTGATCCTGCGGCTGGAGAAGGTCTGCAAGGCCTACAATGTCGGTCTCCCGACCGAGACCGAGGTGCTGCACGACATCG
ATCTCGAGGTCGATCGCGGC

Product: lipoprotein ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MNRWLPFEWVAAVRFLREGRLQTLFIIGGIAIGVAVIVFMSAMLAGLEANFIKRVLTSQPQIQLLTPDQVARPLRNGNRV
IEDATVQRPSQRVISIDQWPKIRAQMLAMPEITAVSPTISGSALAIRGDASRAVTLSGIEPESYFAIVRVPDYIVAGEPR
LSSEDIIIGIELAKDLGAVVGDKLNVQAASGANRVLTVTGLVDLGNKGVNQRAAYVALRTAQSLLGMIGGVTTIDITVQD
IYAAEDIAQRIQAANLVKADSWIKTNAQFFVAVRAQETSNTLIRVFVAMSVAFGIAAVLIVSVIQRSKEIGILRAMGTSR
GQILRVFLLQGGLLGFIGSLFGAALGAGALIYWHAVQRQADGSELFPLILERRLFVITALLATVTGLLAATAPALRAAKL
DPVVAIRG

Sequences:

>Translated_408_residues
MNRWLPFEWVAAVRFLREGRLQTLFIIGGIAIGVAVIVFMSAMLAGLEANFIKRVLTSQPQIQLLTPDQVARPLRNGNRV
IEDATVQRPSQRVISIDQWPKIRAQMLAMPEITAVSPTISGSALAIRGDASRAVTLSGIEPESYFAIVRVPDYIVAGEPR
LSSEDIIIGIELAKDLGAVVGDKLNVQAASGANRVLTVTGLVDLGNKGVNQRAAYVALRTAQSLLGMIGGVTTIDITVQD
IYAAEDIAQRIQAANLVKADSWIKTNAQFFVAVRAQETSNTLIRVFVAMSVAFGIAAVLIVSVIQRSKEIGILRAMGTSR
GQILRVFLLQGGLLGFIGSLFGAALGAGALIYWHAVQRQADGSELFPLILERRLFVITALLATVTGLLAATAPALRAAKL
DPVVAIRG
>Mature_408_residues
MNRWLPFEWVAAVRFLREGRLQTLFIIGGIAIGVAVIVFMSAMLAGLEANFIKRVLTSQPQIQLLTPDQVARPLRNGNRV
IEDATVQRPSQRVISIDQWPKIRAQMLAMPEITAVSPTISGSALAIRGDASRAVTLSGIEPESYFAIVRVPDYIVAGEPR
LSSEDIIIGIELAKDLGAVVGDKLNVQAASGANRVLTVTGLVDLGNKGVNQRAAYVALRTAQSLLGMIGGVTTIDITVQD
IYAAEDIAQRIQAANLVKADSWIKTNAQFFVAVRAQETSNTLIRVFVAMSVAFGIAAVLIVSVIQRSKEIGILRAMGTSR
GQILRVFLLQGGLLGFIGSLFGAALGAGALIYWHAVQRQADGSELFPLILERRLFVITALLATVTGLLAATAPALRAAKL
DPVVAIRG

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=332, Percent_Identity=25, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43639; Mature: 43639

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRWLPFEWVAAVRFLREGRLQTLFIIGGIAIGVAVIVFMSAMLAGLEANFIKRVLTSQP
CCCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QIQLLTPDQVARPLRNGNRVIEDATVQRPSQRVISIDQWPKIRAQMLAMPEITAVSPTIS
CEEEECHHHHHHHHHCCCEEECHHHCCCCCHHEEECCCCHHHHHHHHCCCCCEECCCCCC
GSALAIRGDASRAVTLSGIEPESYFAIVRVPDYIVAGEPRLSSEDIIIGIELAKDLGAVV
CCEEEEECCCCCEEEEECCCCCCEEEEEECCCEEEECCCCCCCCCEEEEEEHHHHHHHHH
GDKLNVQAASGANRVLTVTGLVDLGNKGVNQRAAYVALRTAQSLLGMIGGVTTIDITVQD
CCCCEEEECCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHHH
IYAAEDIAQRIQAANLVKADSWIKTNAQFFVAVRAQETSNTLIRVFVAMSVAFGIAAVLI
HHHHHHHHHHHHHHHHHCCCCCEECCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
VSVIQRSKEIGILRAMGTSRGQILRVFLLQGGLLGFIGSLFGAALGAGALIYWHAVQRQA
HHHHHHHHHCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHEEHHHHHHCC
DGSELFPLILERRLFVITALLATVTGLLAATAPALRAAKLDPVVAIRG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure
MNRWLPFEWVAAVRFLREGRLQTLFIIGGIAIGVAVIVFMSAMLAGLEANFIKRVLTSQP
CCCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QIQLLTPDQVARPLRNGNRVIEDATVQRPSQRVISIDQWPKIRAQMLAMPEITAVSPTIS
CEEEECHHHHHHHHHCCCEEECHHHCCCCCHHEEECCCCHHHHHHHHCCCCCEECCCCCC
GSALAIRGDASRAVTLSGIEPESYFAIVRVPDYIVAGEPRLSSEDIIIGIELAKDLGAVV
CCEEEEECCCCCEEEEECCCCCCEEEEEECCCEEEECCCCCCCCCEEEEEEHHHHHHHHH
GDKLNVQAASGANRVLTVTGLVDLGNKGVNQRAAYVALRTAQSLLGMIGGVTTIDITVQD
CCCCEEEECCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHHH
IYAAEDIAQRIQAANLVKADSWIKTNAQFFVAVRAQETSNTLIRVFVAMSVAFGIAAVLI
HHHHHHHHHHHHHHHHHCCCCCEECCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
VSVIQRSKEIGILRAMGTSRGQILRVFLLQGGLLGFIGSLFGAALGAGALIYWHAVQRQA
HHHHHHHHHCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHEEHHHHHHCC
DGSELFPLILERRLFVITALLATVTGLLAATAPALRAAKLDPVVAIRG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]