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The map label for this gene is kdpE [H]

Identifier: 146342659

GI number: 146342659

Start: 6042562

End: 6043251

Strand: Reverse

Name: kdpE [H]

Synonym: BRADO5826

Alternate gene names: 146342659

Gene position: 6043251-6042562 (Counterclockwise)

Preceding gene: 146342660

Following gene: 146342658

Centisome position: 81.05

GC content: 65.22

Gene sequence:

>690_bases
ATGACCGGTGCGCCCATCAAGGTGCTCGTGATCGACGACGAGCCGCCGATCCGCAAACTGCTGCGGATGGGGCTGGCGAC
GCAGGGCTATGAGATCCTGGAAGCGCCGAGCGGCAAGGTCGCGCTCGACAAGCTCGCCGAGGAGCCGGCCCTGATCATCC
TCGATCTCGGCCTGCCGGACATCGACGGCCACGAACTGTTGCGGACCATCCGGGCGCGCAACGAGAGTATTCCGGTCGTG
GTGCTGTCCAGTCGCGGCGACGAGGCCGGCAAGGTGAAGGCGCTCGATCTCGGTGCCGACGACTACATCACCAAGCCGTT
CGGTATGGACGAGCTGCTGGCGCGGCTGCGCGCCGCCCTGCGCCATCAGCTGCAGGTGCAGGGTGAGCGTCCGCTATTCC
GCACCGGCGATCTTTCCGTCGATCTGGTGCGGCGCATCGTCAAGGTCGGTGAACGCGAGATCAAGCTCTCGCCCAAGGAG
TATGATCTGCTGCGCGTCCTGGTGCAGCACGCCGGCAAGGTGCTGACGCATCGCTTTCTGCTCAAGGAGCTGTGGGACGA
GCTGACCGACGCGCAATATCTGCGCGTCTACGTTCGCCAGCTGCGCCAGAAGATCGAGGCCGATCCTGAACGCCCGTACT
TCGTGCTGACCGAAACCGGCATCGGCTATCGCCTGCGCGCGCCGGATTAG

Upstream 100 bases:

>100_bases
AAGGCCGGATGACCGCCGGCAACCGTGCGGATCGCAGCGGCGCGGTTCTCACGATCCGTCTGCCGGTGCCACCGCAGGCG
AAGACCCTGGAGACTGCGGC

Downstream 100 bases:

>100_bases
CTGTTCTTCATGTTCGCCATTCCCACAAAGCGGAACCTTCGCCTGATCTCGTAATTGCCGTGCTGTCATAGGGAGACCAT
GTCGATGGCACGAACAGCAC

Product: two-component regulatory system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MTGAPIKVLVIDDEPPIRKLLRMGLATQGYEILEAPSGKVALDKLAEEPALIILDLGLPDIDGHELLRTIRARNESIPVV
VLSSRGDEAGKVKALDLGADDYITKPFGMDELLARLRAALRHQLQVQGERPLFRTGDLSVDLVRRIVKVGEREIKLSPKE
YDLLRVLVQHAGKVLTHRFLLKELWDELTDAQYLRVYVRQLRQKIEADPERPYFVLTETGIGYRLRAPD

Sequences:

>Translated_229_residues
MTGAPIKVLVIDDEPPIRKLLRMGLATQGYEILEAPSGKVALDKLAEEPALIILDLGLPDIDGHELLRTIRARNESIPVV
VLSSRGDEAGKVKALDLGADDYITKPFGMDELLARLRAALRHQLQVQGERPLFRTGDLSVDLVRRIVKVGEREIKLSPKE
YDLLRVLVQHAGKVLTHRFLLKELWDELTDAQYLRVYVRQLRQKIEADPERPYFVLTETGIGYRLRAPD
>Mature_228_residues
TGAPIKVLVIDDEPPIRKLLRMGLATQGYEILEAPSGKVALDKLAEEPALIILDLGLPDIDGHELLRTIRARNESIPVVV
LSSRGDEAGKVKALDLGADDYITKPFGMDELLARLRAALRHQLQVQGERPLFRTGDLSVDLVRRIVKVGEREIKLSPKEY
DLLRVLVQHAGKVLTHRFLLKELWDELTDAQYLRVYVRQLRQKIEADPERPYFVLTETGIGYRLRAPD

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=47.7477477477478, Blast_Score=200, Evalue=6e-53,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=37.4449339207048, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=36.1233480176211, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=34.8214285714286, Blast_Score=123, Evalue=8e-30,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=34.6846846846847, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=33.9285714285714, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=34.2222222222222, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=30.4932735426009, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=31.4159292035398, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1788394, Length=242, Percent_Identity=33.0578512396694, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=29.3103448275862, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=30.5676855895196, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=32.7510917030568, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=31.1965811965812, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=33.8983050847458, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1790437, Length=132, Percent_Identity=34.8484848484849, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790299, Length=130, Percent_Identity=33.0769230769231, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=134, Percent_Identity=32.089552238806, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787487, Length=140, Percent_Identity=33.5714285714286, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788191, Length=111, Percent_Identity=35.1351351351351, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25887; Mature: 25755

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGAPIKVLVIDDEPPIRKLLRMGLATQGYEILEAPSGKVALDKLAEEPALIILDLGLPD
CCCCCEEEEEECCCCHHHHHHHHCCCCCCCCEEECCCCCHHHHHHCCCCCEEEEECCCCC
IDGHELLRTIRARNESIPVVVLSSRGDEAGKVKALDLGADDYITKPFGMDELLARLRAAL
CCHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHH
RHQLQVQGERPLFRTGDLSVDLVRRIVKVGEREIKLSPKEYDLLRVLVQHAGKVLTHRFL
HHHHHCCCCCCEEECCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHH
LKELWDELTDAQYLRVYVRQLRQKIEADPERPYFVLTETGIGYRLRAPD
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCC
>Mature Secondary Structure 
TGAPIKVLVIDDEPPIRKLLRMGLATQGYEILEAPSGKVALDKLAEEPALIILDLGLPD
CCCCEEEEEECCCCHHHHHHHHCCCCCCCCEEECCCCCHHHHHHCCCCCEEEEECCCCC
IDGHELLRTIRARNESIPVVVLSSRGDEAGKVKALDLGADDYITKPFGMDELLARLRAAL
CCHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHH
RHQLQVQGERPLFRTGDLSVDLVRRIVKVGEREIKLSPKEYDLLRVLVQHAGKVLTHRFL
HHHHHCCCCCCEEECCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHH
LKELWDELTDAQYLRVYVRQLRQKIEADPERPYFVLTETGIGYRLRAPD
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]