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The map label for this gene is gpx [C]

Identifier: 146342623

GI number: 146342623

Start: 5990037

End: 5990513

Strand: Reverse

Name: gpx [C]

Synonym: BRADO5788

Alternate gene names: 146342623

Gene position: 5990513-5990037 (Counterclockwise)

Preceding gene: 146342624

Following gene: 146342622

Centisome position: 80.34

GC content: 62.89

Gene sequence:

>477_bases
ATGGCGAGCATCTACGATTTCACCGCATCCTCGCTGACCGGCGAGGAGGTGCCGCTGAACCGCTTCGAGGGCCAGGTGCT
CTTGATCGTCAACACCGCCAGCGCCTGCGGTTTCACGCCGCAATATCGCGGCCTCGAGGCGCTGCACCGCGCCTATGCCG
ACAGGGGCTTTGCCGTGCTCGGATTTCCCTGTAACCAGTTCGGCGCCCAGGAGCCTGGCACGGCCGCGGAGATCGGCGCG
TTCTGCTCGACAAAGTACGATGTCACCTTCCCGCTGTTCGCGAAGATCGACGTCAACGGCGCGCACGCGCATCCGCTCTA
CAAGTTCCTGAAGGGCGAGAAGACCGGCCTGTTGGGCTCGGCGATCAAATGGAATTTCACCAAATTCCTGGTCGATCGCG
CTGGCCATGTGGTGTCGCGCCATGCGCCGACCACCACGCCCGAGGCGTTGAAGAAAGAGATCGAGGCACTGCTGTGA

Upstream 100 bases:

>100_bases
TCGTCGGCCAGCGGTTTCGCGAGGACATGTGCCTTGCCGCCGGCGAAGCCATCGAGGCCGGCGGCACCCCGCCGTCGCCG
ATCGATCCGGTGCTAGGCTG

Downstream 100 bases:

>100_bases
GCGACAACGAGACCTTCACCTTCCCGGACCGCCTCTCGGTCGATCCGAAGAGCCCCTACTACAACGCGGAGATCCTGTCG
CGCGACGTCGGCATCCGCTT

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MASIYDFTASSLTGEEVPLNRFEGQVLLIVNTASACGFTPQYRGLEALHRAYADRGFAVLGFPCNQFGAQEPGTAAEIGA
FCSTKYDVTFPLFAKIDVNGAHAHPLYKFLKGEKTGLLGSAIKWNFTKFLVDRAGHVVSRHAPTTTPEALKKEIEALL

Sequences:

>Translated_158_residues
MASIYDFTASSLTGEEVPLNRFEGQVLLIVNTASACGFTPQYRGLEALHRAYADRGFAVLGFPCNQFGAQEPGTAAEIGA
FCSTKYDVTFPLFAKIDVNGAHAHPLYKFLKGEKTGLLGSAIKWNFTKFLVDRAGHVVSRHAPTTTPEALKKEIEALL
>Mature_157_residues
ASIYDFTASSLTGEEVPLNRFEGQVLLIVNTASACGFTPQYRGLEALHRAYADRGFAVLGFPCNQFGAQEPGTAAEIGAF
CSTKYDVTFPLFAKIDVNGAHAHPLYKFLKGEKTGLLGSAIKWNFTKFLVDRAGHVVSRHAPTTTPEALKKEIEALL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=155, Percent_Identity=45.8064516129032, Blast_Score=142, Evalue=1e-34,
Organism=Homo sapiens, GI90903240, Length=155, Percent_Identity=45.8064516129032, Blast_Score=142, Evalue=2e-34,
Organism=Homo sapiens, GI15618997, Length=155, Percent_Identity=45.1612903225806, Blast_Score=134, Evalue=3e-32,
Organism=Homo sapiens, GI90903238, Length=140, Percent_Identity=46.4285714285714, Blast_Score=119, Evalue=8e-28,
Organism=Homo sapiens, GI192455698, Length=159, Percent_Identity=37.7358490566038, Blast_Score=117, Evalue=3e-27,
Organism=Homo sapiens, GI6006001, Length=179, Percent_Identity=37.9888268156425, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI4557629, Length=183, Percent_Identity=37.1584699453552, Blast_Score=99, Evalue=1e-21,
Organism=Homo sapiens, GI41406084, Length=184, Percent_Identity=38.5869565217391, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI33186887, Length=171, Percent_Identity=38.5964912280702, Blast_Score=94, Evalue=4e-20,
Organism=Homo sapiens, GI32967607, Length=183, Percent_Identity=34.4262295081967, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1788003, Length=166, Percent_Identity=47.5903614457831, Blast_Score=156, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI17535473, Length=159, Percent_Identity=52.8301886792453, Blast_Score=173, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17506887, Length=159, Percent_Identity=48.4276729559748, Blast_Score=164, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI193210707, Length=162, Percent_Identity=45.679012345679, Blast_Score=147, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71993584, Length=158, Percent_Identity=42.4050632911392, Blast_Score=144, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI193209493, Length=164, Percent_Identity=37.1951219512195, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17550320, Length=166, Percent_Identity=35.5421686746988, Blast_Score=102, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17507603, Length=107, Percent_Identity=40.1869158878505, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=35.7894736842105, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193210709, Length=72, Percent_Identity=45.8333333333333, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=36.8421052631579, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322228, Length=159, Percent_Identity=52.8301886792453, Blast_Score=190, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6319721, Length=158, Percent_Identity=53.1645569620253, Blast_Score=189, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6322826, Length=159, Percent_Identity=47.1698113207547, Blast_Score=149, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=49.375, Blast_Score=161, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24656772, Length=160, Percent_Identity=49.375, Blast_Score=160, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24656767, Length=160, Percent_Identity=49.375, Blast_Score=160, Evalue=3e-40,
Organism=Drosophila melanogaster, GI85726443, Length=158, Percent_Identity=44.9367088607595, Blast_Score=123, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17155; Mature: 17024

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIYDFTASSLTGEEVPLNRFEGQVLLIVNTASACGFTPQYRGLEALHRAYADRGFAVL
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEE
GFPCNQFGAQEPGTAAEIGAFCSTKYDVTFPLFAKIDVNGAHAHPLYKFLKGEKTGLLGS
ECCHHHCCCCCCCCHHHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHHHHCCCCCCCCCC
AIKWNFTKFLVDRAGHVVSRHAPTTTPEALKKEIEALL
HHHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
ASIYDFTASSLTGEEVPLNRFEGQVLLIVNTASACGFTPQYRGLEALHRAYADRGFAVL
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEE
GFPCNQFGAQEPGTAAEIGAFCSTKYDVTFPLFAKIDVNGAHAHPLYKFLKGEKTGLLGS
ECCHHHCCCCCCCCHHHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHHHHCCCCCCCCCC
AIKWNFTKFLVDRAGHVVSRHAPTTTPEALKKEIEALL
HHHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]