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The map label for this gene is galE [H]

Identifier: 146342067

GI number: 146342067

Start: 5419762

End: 5420775

Strand: Direct

Name: galE [H]

Synonym: BRADO5207

Alternate gene names: 146342067

Gene position: 5419762-5420775 (Clockwise)

Preceding gene: 146342065

Following gene: 146342068

Centisome position: 72.68

GC content: 67.65

Gene sequence:

>1014_bases
ATGACCGTGCTTGTCACCGGCGGCGCCGGCTATATCGGCAGCCACATGGTGCTCGCGCTGGCCGAGGCCGGCGAAAGCGT
CGTGGTGATCGACAACCTCTCGACCGGCTTCTCCGCCTTCGTGCCGAGCGAGGTGCCGCTGTTCATCGGCGATGCCGGCG
ACGAGAACCTGGTCGACGGCGTCATCAGCCAGCACGGGGTCGACAGCATCATCCATTTCGCCGGCTCGGTCGTGGTGCCG
GAATCGGTGCGCGATCCGCTGCTGTATTACCGCAACAACACCATGACCACGCGCAGCCTGTTGAATGCGGCGGTCAAGCG
CGGCGTGAGCCGTTTCATCTTCTCCTCGACCGCGGCCGTCTACGGCAATCCGGCCCAGGTTCCGGTGCCCGAGACCGCGC
CGACGCGGCCGACCTCGCCCTATGGCAGCTCGAAGCTGATGGCCGAGATCATGCTGCACGATACCGCCGCGGCGTATGAG
CTCAACTACGCCGTGCTGCGCTATTTCAACGTCGCCGGCGCCGATCCGCAGGGACGCATCGGGCTCGCCACCGTCGGCGC
CACGCATCTGATGAAGATCGCGATGGAGGTCGCCACCGGCCAGCGCGCCAAGATCGACGTCTACGGCACCGATTATTCGA
CACCGGACGGCACCGCGGTCCGCGACTTCATCCATGTCTGCGACCTCGTCCAGGCGCATCGCGCCGCGCTGGCTTATCTG
CGCGCCGGCGGCCCCTCGGTCACGCTGAATTGCGGCTATGGCCGCGGCTATTCCGTGCTCGAGACCATCGAGGCGGTCCG
ACGCGCCTCCGGCCGCGCCATTCCGGTGCAGACCGCGCCGCGCCGCCCCGGCGACATCATGAGCATGGTCGCCGACACCA
GCCGGCTCCGGGCGACGCTCGACTGGACGCCGGCCTATGACAATCTGGACACAATCGCGGCCCACGCGCTGGCCTGGGAG
CACAAACTGTTCCTGGAACGCCACAGCCATGGGGAGCAGCGGGCCTCGGCCTAG

Upstream 100 bases:

>100_bases
GCAACATTGAGCACCATCGCCAGTTCGCATCCGCGTTCAACCGGTCCTTCATTTCGCGGGCGTTAGCGTCGCGCAAAACA
AACAGGGATCGCGTCAAACA

Downstream 100 bases:

>100_bases
AATCAAGCACTTAAGCCCGAAGCGGGGGGCTTGAAAAAGCCGCCCCGAGCGGGCAAGCACTCCTGGTCCGCCCGGCGATT
TGCCCGCGCGGCCAGGGACC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTVLVTGGAGYIGSHMVLALAEAGESVVVIDNLSTGFSAFVPSEVPLFIGDAGDENLVDGVISQHGVDSIIHFAGSVVVP
ESVRDPLLYYRNNTMTTRSLLNAAVKRGVSRFIFSSTAAVYGNPAQVPVPETAPTRPTSPYGSSKLMAEIMLHDTAAAYE
LNYAVLRYFNVAGADPQGRIGLATVGATHLMKIAMEVATGQRAKIDVYGTDYSTPDGTAVRDFIHVCDLVQAHRAALAYL
RAGGPSVTLNCGYGRGYSVLETIEAVRRASGRAIPVQTAPRRPGDIMSMVADTSRLRATLDWTPAYDNLDTIAAHALAWE
HKLFLERHSHGEQRASA

Sequences:

>Translated_337_residues
MTVLVTGGAGYIGSHMVLALAEAGESVVVIDNLSTGFSAFVPSEVPLFIGDAGDENLVDGVISQHGVDSIIHFAGSVVVP
ESVRDPLLYYRNNTMTTRSLLNAAVKRGVSRFIFSSTAAVYGNPAQVPVPETAPTRPTSPYGSSKLMAEIMLHDTAAAYE
LNYAVLRYFNVAGADPQGRIGLATVGATHLMKIAMEVATGQRAKIDVYGTDYSTPDGTAVRDFIHVCDLVQAHRAALAYL
RAGGPSVTLNCGYGRGYSVLETIEAVRRASGRAIPVQTAPRRPGDIMSMVADTSRLRATLDWTPAYDNLDTIAAHALAWE
HKLFLERHSHGEQRASA
>Mature_336_residues
TVLVTGGAGYIGSHMVLALAEAGESVVVIDNLSTGFSAFVPSEVPLFIGDAGDENLVDGVISQHGVDSIIHFAGSVVVPE
SVRDPLLYYRNNTMTTRSLLNAAVKRGVSRFIFSSTAAVYGNPAQVPVPETAPTRPTSPYGSSKLMAEIMLHDTAAAYEL
NYAVLRYFNVAGADPQGRIGLATVGATHLMKIAMEVATGQRAKIDVYGTDYSTPDGTAVRDFIHVCDLVQAHRAALAYLR
AGGPSVTLNCGYGRGYSVLETIEAVRRASGRAIPVQTAPRRPGDIMSMVADTSRLRATLDWTPAYDNLDTIAAHALAWEH
KLFLERHSHGEQRASA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=336, Percent_Identity=40.7738095238095, Blast_Score=225, Evalue=4e-59,
Organism=Homo sapiens, GI56118217, Length=336, Percent_Identity=40.7738095238095, Blast_Score=225, Evalue=4e-59,
Organism=Homo sapiens, GI189083684, Length=336, Percent_Identity=40.7738095238095, Blast_Score=225, Evalue=4e-59,
Organism=Homo sapiens, GI7657641, Length=319, Percent_Identity=26.0188087774295, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI42516563, Length=309, Percent_Identity=27.1844660194175, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1786974, Length=342, Percent_Identity=40.9356725146199, Blast_Score=232, Evalue=2e-62,
Organism=Escherichia coli, GI1790049, Length=273, Percent_Identity=27.4725274725275, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI48994969, Length=334, Percent_Identity=25.748502994012, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788353, Length=340, Percent_Identity=25, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=341, Percent_Identity=38.41642228739, Blast_Score=217, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI71982038, Length=343, Percent_Identity=38.1924198250729, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17539532, Length=310, Percent_Identity=26.1290322580645, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17568069, Length=186, Percent_Identity=30.1075268817204, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=318, Percent_Identity=40.5660377358491, Blast_Score=232, Evalue=6e-62,
Organism=Drosophila melanogaster, GI19923002, Length=340, Percent_Identity=40, Blast_Score=220, Evalue=8e-58,
Organism=Drosophila melanogaster, GI21356223, Length=312, Percent_Identity=27.5641025641026, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35976; Mature: 35845

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLVTGGAGYIGSHMVLALAEAGESVVVIDNLSTGFSAFVPSEVPLFIGDAGDENLVDG
CEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHCCCCCCCEEEECCCCCHHHHH
VISQHGVDSIIHFAGSVVVPESVRDPLLYYRNNTMTTRSLLNAAVKRGVSRFIFSSTAAV
HHHHCCHHHHHHHHCCEECCHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHH
YGNPAQVPVPETAPTRPTSPYGSSKLMAEIMLHDTAAAYELNYAVLRYFNVAGADPQGRI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCE
GLATVGATHLMKIAMEVATGQRAKIDVYGTDYSTPDGTAVRDFIHVCDLVQAHRAALAYL
EEEHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RAGGPSVTLNCGYGRGYSVLETIEAVRRASGRAIPVQTAPRRPGDIMSMVADTSRLRATL
HCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHEEEE
DWTPAYDNLDTIAAHALAWEHKLFLERHSHGEQRASA
ECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
TVLVTGGAGYIGSHMVLALAEAGESVVVIDNLSTGFSAFVPSEVPLFIGDAGDENLVDG
EEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHCCCCCCCEEEECCCCCHHHHH
VISQHGVDSIIHFAGSVVVPESVRDPLLYYRNNTMTTRSLLNAAVKRGVSRFIFSSTAAV
HHHHCCHHHHHHHHCCEECCHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHH
YGNPAQVPVPETAPTRPTSPYGSSKLMAEIMLHDTAAAYELNYAVLRYFNVAGADPQGRI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCE
GLATVGATHLMKIAMEVATGQRAKIDVYGTDYSTPDGTAVRDFIHVCDLVQAHRAALAYL
EEEHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RAGGPSVTLNCGYGRGYSVLETIEAVRRASGRAIPVQTAPRRPGDIMSMVADTSRLRATL
HCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHEEEE
DWTPAYDNLDTIAAHALAWEHKLFLERHSHGEQRASA
ECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]