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The map label for this gene is 146342013

Identifier: 146342013

GI number: 146342013

Start: 5351945

End: 5354164

Strand: Reverse

Name: 146342013

Synonym: BRADO5150

Alternate gene names: NA

Gene position: 5354164-5351945 (Counterclockwise)

Preceding gene: 146342014

Following gene: 146342011

Centisome position: 71.8

GC content: 68.33

Gene sequence:

>2220_bases
TTGGCAGGCAATGTCGGTTCGCGCGCATTTCAGAATGCGAGGCTCCTGAAGCAGCACCGCAAGCAGGTCGATGATCTCTT
GCCGCGCGCGGTCGCGGCCTATCGTGCCGGCACGCTGGCCGAGGCGCAGGCGATCTGCAGCCGGATCCTGGCGCTGCTCC
CTCACCATTTCGACACGCTGCATCTGCTCGGCGTGGTGGCGCTCGATGGCGGCCAGCTCGATCTCGCCGAGCAGGCGCTG
ACCAGGGCGGTCGAGATCGAGCCGCGCCATGCCGAGGCGCTCTCCAATCTCGGTCTCGCGCTGTTCAACCGCAAGCGCTA
CGAGGAGGCACGCAAGTGCCAGGAGCGGGCGGTCGCGCTGAAGCCCAATCTGTTGGTCGCGCTGACGGGGCTCGGCAATA
CGCTGATGCGGCTGGGTCTGCCCGAGGAGGCGATCGCGGCGCACGACCGCGCGATCGCGCTCAAGCCCGACTTCGCGGAC
GCCTATTGCAATCGCGGCATGGCGCTGCTGCCGCTCGGCCGCAACGTCGAGGCCGACCAGAGCTTCGACCGGGCGCTGTC
GCTCAACCCGCGCCACATGGAGGCGATGTTCGGCAAGGGCCTCGCCAGCATCGCTCTGCGCCATTCCAACGCGGCGCTCG
CCGCGTTCGATGCCGCGCTCGCGATCCGGCCGCGCGCCGCGCAGGTGCTGGCGCAGCGCGGCCGGCTGCATCAGCAGGCC
GGCCGGTTCGATCCCGCGATGGCCGATTTCCAGGCGGCGCTTGCGATCGATCCGCGGCAGGACGTGGCGCTGATGGGCTT
TGCCCAGCTCAGCGTCATCAGGGACAACATCGCGCCGGCGATGGAGGCCTGCCGCAAGGTGCTCGAGCAAAATCCGCAGT
CGGAGGTCGCCTGGACCTGGCTCGGCGAATGCTTCTGCAAGCAGGGCGATCTCGCCGCGGGTCTCGCGCATTTCGAGCGG
GCGCTCGAGATCAAGCCTGATTTCGGGGACGCGATCACCGCCAAGATCTTCCTGCTCGACTTCATGCCAGACACCGATTT
CGCCCAGCATCAGGCGGTCAGGCGCGAATGGTGGACACGGATCGGCGCAGAGATCGCGCGGCGGCCGACGCCGGTGCGCG
CGCGCGATCCGGAGCGGCGGCTCACCATCGGCTATGTCTCGTCCGACTTCCGGACGCATTCGGCCGCGCTGGTGTTCCTG
CCGGTGCTGCGCCATCACGACCACCATTCGTTCAAGGTCGTCTGCTATTCCTGCTCGCCGCTGCAGGACACGATGACGGC
GCAGTGCCGCGCCGTCGCCGACGTCTGGGTCGATGCCTGGCAGATGTCCGACGACGAACTGACGGAGCGCATCGAGGCCG
ACGCCGTCGACATCCTGGTCGATCTGTCCGGCCATTCTGCGGGCAACCGCCTGCCGGTGTTCGCGCGCAAGCCGGCGCCC
ATCCAGGTCACGGCCTGGGGCAGCGGCACCGGCACGGGATTGCCGACGATGGACTACTTCTTCGCCGATCCGGTCACCGT
GCCGGAAGATGTCCGTCACCTCTTTGCCGAGCAGGTCTACGACCTGCCCGCGGTCATCACCACCGACCCGCTGCAGGGCT
GGCAGCCGACGCCGCTGCCGATGCTGCGCAACGGCCATGTGACGTTCGGCGTGTTCAACCGCATCGACAAGATCTCCGAT
CCCGCGCTCGCGCTGTGGGCGCGGCTGATGGCGGCGCTGCCGAACTCGCGCATCGTCATCAAGAACGGCGCGCTCGACGA
TTCCTTGGTGCGCAACGCACTCGTGGCGCGCTTCGTCGCGCATGGGATTGCCGAGGGGCGCATCACCTGCCTCGGCCTGT
CGTCGCGGGAGCAGCACATCGCGCAGTTCGCAGCCATCGACATGTCGCTCGATCCGTTCCCGCAGAATGGCGGGGTCAGC
ACCTGGGAGTCGCTGCAGGCCGGCGTGCCCGTGATCTGCAAATTGGGGCGGAGCGCCGCGGGCCGCGCCGCCGCGGCCAT
CAACACCGCGGTGGGGCTGCCCGGCTGGGTGGCCGCGGACGACGAAGACTATGTCGCGATGGCGTTGAAGCATGCCACGC
AGCCGGAGGAGTTGGCGAAGCTGCGCGCGGCGCTGCCGGCCATGGCCGCCACTTCCGAGGCCGGCAACGTCGAGACCTAC
ACACGCAAGGTCGAGGAGGGCTATCGTCGGTTCTGGTGTCGTTACTGCACCTCCTCCTGA

Upstream 100 bases:

>100_bases
CGTGCTGTTGCGCGGATTGCGCAGGTCAAGTCCAAGTCCTGTTCCGGTGCTACGAGTTGCGTTGAGGTGAGTGCTTTGCG
TCAGCCCGTGGAGACCCCTC

Downstream 100 bases:

>100_bases
CCTCCGACTACAGGCGCGCGGCGCCGACGATGCGGCCATCCGGCGCCTCGAGCAGCACCGCGACATCCTCGCCCTCGGGC
ATCGGCTCGCTCAGCCGCAG

Product: O-linked N-acetylglucosamine transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 739; Mature: 738

Protein sequence:

>739_residues
MAGNVGSRAFQNARLLKQHRKQVDDLLPRAVAAYRAGTLAEAQAICSRILALLPHHFDTLHLLGVVALDGGQLDLAEQAL
TRAVEIEPRHAEALSNLGLALFNRKRYEEARKCQERAVALKPNLLVALTGLGNTLMRLGLPEEAIAAHDRAIALKPDFAD
AYCNRGMALLPLGRNVEADQSFDRALSLNPRHMEAMFGKGLASIALRHSNAALAAFDAALAIRPRAAQVLAQRGRLHQQA
GRFDPAMADFQAALAIDPRQDVALMGFAQLSVIRDNIAPAMEACRKVLEQNPQSEVAWTWLGECFCKQGDLAAGLAHFER
ALEIKPDFGDAITAKIFLLDFMPDTDFAQHQAVRREWWTRIGAEIARRPTPVRARDPERRLTIGYVSSDFRTHSAALVFL
PVLRHHDHHSFKVVCYSCSPLQDTMTAQCRAVADVWVDAWQMSDDELTERIEADAVDILVDLSGHSAGNRLPVFARKPAP
IQVTAWGSGTGTGLPTMDYFFADPVTVPEDVRHLFAEQVYDLPAVITTDPLQGWQPTPLPMLRNGHVTFGVFNRIDKISD
PALALWARLMAALPNSRIVIKNGALDDSLVRNALVARFVAHGIAEGRITCLGLSSREQHIAQFAAIDMSLDPFPQNGGVS
TWESLQAGVPVICKLGRSAAGRAAAAINTAVGLPGWVAADDEDYVAMALKHATQPEELAKLRAALPAMAATSEAGNVETY
TRKVEEGYRRFWCRYCTSS

Sequences:

>Translated_739_residues
MAGNVGSRAFQNARLLKQHRKQVDDLLPRAVAAYRAGTLAEAQAICSRILALLPHHFDTLHLLGVVALDGGQLDLAEQAL
TRAVEIEPRHAEALSNLGLALFNRKRYEEARKCQERAVALKPNLLVALTGLGNTLMRLGLPEEAIAAHDRAIALKPDFAD
AYCNRGMALLPLGRNVEADQSFDRALSLNPRHMEAMFGKGLASIALRHSNAALAAFDAALAIRPRAAQVLAQRGRLHQQA
GRFDPAMADFQAALAIDPRQDVALMGFAQLSVIRDNIAPAMEACRKVLEQNPQSEVAWTWLGECFCKQGDLAAGLAHFER
ALEIKPDFGDAITAKIFLLDFMPDTDFAQHQAVRREWWTRIGAEIARRPTPVRARDPERRLTIGYVSSDFRTHSAALVFL
PVLRHHDHHSFKVVCYSCSPLQDTMTAQCRAVADVWVDAWQMSDDELTERIEADAVDILVDLSGHSAGNRLPVFARKPAP
IQVTAWGSGTGTGLPTMDYFFADPVTVPEDVRHLFAEQVYDLPAVITTDPLQGWQPTPLPMLRNGHVTFGVFNRIDKISD
PALALWARLMAALPNSRIVIKNGALDDSLVRNALVARFVAHGIAEGRITCLGLSSREQHIAQFAAIDMSLDPFPQNGGVS
TWESLQAGVPVICKLGRSAAGRAAAAINTAVGLPGWVAADDEDYVAMALKHATQPEELAKLRAALPAMAATSEAGNVETY
TRKVEEGYRRFWCRYCTSS
>Mature_738_residues
AGNVGSRAFQNARLLKQHRKQVDDLLPRAVAAYRAGTLAEAQAICSRILALLPHHFDTLHLLGVVALDGGQLDLAEQALT
RAVEIEPRHAEALSNLGLALFNRKRYEEARKCQERAVALKPNLLVALTGLGNTLMRLGLPEEAIAAHDRAIALKPDFADA
YCNRGMALLPLGRNVEADQSFDRALSLNPRHMEAMFGKGLASIALRHSNAALAAFDAALAIRPRAAQVLAQRGRLHQQAG
RFDPAMADFQAALAIDPRQDVALMGFAQLSVIRDNIAPAMEACRKVLEQNPQSEVAWTWLGECFCKQGDLAAGLAHFERA
LEIKPDFGDAITAKIFLLDFMPDTDFAQHQAVRREWWTRIGAEIARRPTPVRARDPERRLTIGYVSSDFRTHSAALVFLP
VLRHHDHHSFKVVCYSCSPLQDTMTAQCRAVADVWVDAWQMSDDELTERIEADAVDILVDLSGHSAGNRLPVFARKPAPI
QVTAWGSGTGTGLPTMDYFFADPVTVPEDVRHLFAEQVYDLPAVITTDPLQGWQPTPLPMLRNGHVTFGVFNRIDKISDP
ALALWARLMAALPNSRIVIKNGALDDSLVRNALVARFVAHGIAEGRITCLGLSSREQHIAQFAAIDMSLDPFPQNGGVST
WESLQAGVPVICKLGRSAAGRAAAAINTAVGLPGWVAADDEDYVAMALKHATQPEELAKLRAALPAMAATSEAGNVETYT
RKVEEGYRRFWCRYCTSS

Specific function: Unknown

COG id: COG3914

COG function: function code O; Predicted O-linked N-acetylglucosamine transferase, SPINDLY family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=599, Percent_Identity=26.3772954924875, Blast_Score=172, Evalue=2e-42,
Organism=Homo sapiens, GI32307150, Length=599, Percent_Identity=26.3772954924875, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI301336134, Length=288, Percent_Identity=25.3472222222222, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI83415184, Length=288, Percent_Identity=25.3472222222222, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI167466177, Length=314, Percent_Identity=21.3375796178344, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI167466175, Length=314, Percent_Identity=21.3375796178344, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI170784867, Length=212, Percent_Identity=26.4150943396226, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI296531396, Length=204, Percent_Identity=27.9411764705882, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI310123097, Length=235, Percent_Identity=23.4042553191489, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI310110582, Length=235, Percent_Identity=23.4042553191489, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI310131789, Length=235, Percent_Identity=23.4042553191489, Blast_Score=70, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI115532690, Length=607, Percent_Identity=25.7001647446458, Blast_Score=140, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI115532692, Length=607, Percent_Identity=25.7001647446458, Blast_Score=139, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI25147174, Length=223, Percent_Identity=28.2511210762332, Blast_Score=76, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319387, Length=192, Percent_Identity=25.5208333333333, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17647755, Length=535, Percent_Identity=25.981308411215, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24585827, Length=535, Percent_Identity=25.981308411215, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24585829, Length=535, Percent_Identity=25.981308411215, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24647123, Length=231, Percent_Identity=25.974025974026, Blast_Score=67, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 80863; Mature: 80732

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNVGSRAFQNARLLKQHRKQVDDLLPRAVAAYRAGTLAEAQAICSRILALLPHHFDTL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHH
HLLGVVALDGGQLDLAEQALTRAVEIEPRHAEALSNLGLALFNRKRYEEARKCQERAVAL
HHHEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCEEE
KPNLLVALTGLGNTLMRLGLPEEAIAAHDRAIALKPDFADAYCNRGMALLPLGRNVEADQ
CCCEEEEEECCCHHHHHCCCCHHHHHCCCCEEEECCCHHHHHHCCCEEEEECCCCCCCCC
SFDRALSLNPRHMEAMFGKGLASIALRHSNAALAAFDAALAIRPRAAQVLAQRGRLHQQA
CHHHHHCCCHHHHHHHHHCCHHHHHEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GRFDPAMADFQAALAIDPRQDVALMGFAQLSVIRDNIAPAMEACRKVLEQNPQSEVAWTW
CCCCCHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LGECFCKQGDLAAGLAHFERALEIKPDFGDAITAKIFLLDFMPDTDFAQHQAVRREWWTR
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHEEEEEEEECCCCCCHHHHHHHHHHHHHH
IGAEIARRPTPVRARDPERRLTIGYVSSDFRTHSAALVFLPVLRHHDHHSFKVVCYSCSP
HHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCC
LQDTMTAQCRAVADVWVDAWQMSDDELTERIEADAVDILVDLSGHSAGNRLPVFARKPAP
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEECCCCC
IQVTAWGSGTGTGLPTMDYFFADPVTVPEDVRHLFAEQVYDLPAVITTDPLQGWQPTPLP
EEEEEECCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCC
MLRNGHVTFGVFNRIDKISDPALALWARLMAALPNSRIVIKNGALDDSLVRNALVARFVA
CCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHH
HGIAEGRITCLGLSSREQHIAQFAAIDMSLDPFPQNGGVSTWESLQAGVPVICKLGRSAA
HHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCHHHHHCCCCCC
GRAAAAINTAVGLPGWVAADDEDYVAMALKHATQPEELAKLRAALPAMAATSEAGNVETY
CCHHHHHHHHCCCCCCEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHH
TRKVEEGYRRFWCRYCTSS
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGNVGSRAFQNARLLKQHRKQVDDLLPRAVAAYRAGTLAEAQAICSRILALLPHHFDTL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHH
HLLGVVALDGGQLDLAEQALTRAVEIEPRHAEALSNLGLALFNRKRYEEARKCQERAVAL
HHHEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCEEE
KPNLLVALTGLGNTLMRLGLPEEAIAAHDRAIALKPDFADAYCNRGMALLPLGRNVEADQ
CCCEEEEEECCCHHHHHCCCCHHHHHCCCCEEEECCCHHHHHHCCCEEEEECCCCCCCCC
SFDRALSLNPRHMEAMFGKGLASIALRHSNAALAAFDAALAIRPRAAQVLAQRGRLHQQA
CHHHHHCCCHHHHHHHHHCCHHHHHEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GRFDPAMADFQAALAIDPRQDVALMGFAQLSVIRDNIAPAMEACRKVLEQNPQSEVAWTW
CCCCCHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LGECFCKQGDLAAGLAHFERALEIKPDFGDAITAKIFLLDFMPDTDFAQHQAVRREWWTR
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHEEEEEEEECCCCCCHHHHHHHHHHHHHH
IGAEIARRPTPVRARDPERRLTIGYVSSDFRTHSAALVFLPVLRHHDHHSFKVVCYSCSP
HHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCC
LQDTMTAQCRAVADVWVDAWQMSDDELTERIEADAVDILVDLSGHSAGNRLPVFARKPAP
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEECCCCC
IQVTAWGSGTGTGLPTMDYFFADPVTVPEDVRHLFAEQVYDLPAVITTDPLQGWQPTPLP
EEEEEECCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCC
MLRNGHVTFGVFNRIDKISDPALALWARLMAALPNSRIVIKNGALDDSLVRNALVARFVA
CCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHH
HGIAEGRITCLGLSSREQHIAQFAAIDMSLDPFPQNGGVSTWESLQAGVPVICKLGRSAA
HHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCHHHHHCCCCCC
GRAAAAINTAVGLPGWVAADDEDYVAMALKHATQPEELAKLRAALPAMAATSEAGNVETY
CCHHHHHHHHCCCCCCEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHH
TRKVEEGYRRFWCRYCTSS
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]