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The map label for this gene is cutL [H]

Identifier: 146342004

GI number: 146342004

Start: 5339603

End: 5341912

Strand: Reverse

Name: cutL [H]

Synonym: BRADO5140

Alternate gene names: 146342004

Gene position: 5341912-5339603 (Counterclockwise)

Preceding gene: 146342005

Following gene: 146342003

Centisome position: 71.64

GC content: 66.88

Gene sequence:

>2310_bases
ATGGCAGCTCCAATCAAGTTCGGTATGGGACAAAGCGTTCTCCGGAAAGAGGATGACGCGCTGATTCGCGGCAAGGGCCG
CTATACCGACGATCTCGCGCCATCCGCCGCCCTGCATGCCCTCGTGCTGCGCTCGCCGCAGGCCCATGCCAAGTTCACCA
TCGACGTGTCCGCAGCGCGGCTGCTGCCGGGCGTGGCGCTGATCCTCACCGCCGAGGACACTGCGGAACTCGGCGGCCTG
CCGTGCCTGTTCAACCTCGAGACCGATCCCTTCACCGCGCCGCCTTATCCGATCCTGGCCAAGGACGAGGTGCGCCATGT
CGGCGACGCCGTGGCCTTCGTCGTGGCCGACACGCTCGATCACGCGCGCGACGCGCTCGAGGCAATCAAGGTCGAATGGA
CGACCTTGCCGGCGGTCACCGGCGTCGTGAATGCGATCAAGCCGGGCGCGCCGCAGGTCTGGCCGGATCACAAGGGCAAC
GTGCTGTTCGACGTCTCGATCGGCGACAAGGCCGCGACCGAGGCGGCATTTGCGAAAGCTCACGCGGTCGCCGAGATCCG
CATCGTCAATCCGCGCGTGGTCGCGAGCTTCATGGAGACGCGCGCCGCCGTCTGCGAATACGACACCAAGCGCGATCATC
TGACGCTCACCGCCGGCAGCCAGGGCAGCCACCGGCTGCGCGACATCCTCTGCCAGAACGTGCTGAAGATCCCGACCGAG
AAGATGCGGGTGATCTGCCCGGATGTCGGCGGCGGCTTCGGCACGAAGCTGTTTCCGTACCGGGAATATGCGCTGGTCGC
CGTGGCAGCGCAGCGGCTGCGCAAGTCGGTGCGCTGGGCCGCCGACCGCTCCGAGCATTTCATGGGCGACGCGCAGGGCC
GCGACAACGTCACGACAGCGAGGATGGCGCTCGCCGAGGACGGCAAGTTCCTCGCGATGGACGTCGACCTGATGGGCGAC
ATGGGCGCCTATCTGTCGACGTTTGCGCCCTACATCCCGCATGGCGGCGCCGGCATGCTGCCGGGCCTCTACGACATCCA
GAAATTCCACTGCCGGGTGCGCACGATCTTCACCCATACCGTGCCGGTCGATGCCTATCGCGGCGCCGGCAGGCCGGAGG
CCGCCTATGTCGTCGAGCGTCTCGTCGATGCCTGCGCGCGCAAGCTCGACATGTCGGTCGATGCCATCCGGCGCAAGAAC
TTCATCCCGCCGCGCGCGCTGCCTTACAAGACTGCGACCGGCAAGGTGTACGATTCCGGCGACTTCAACGCGCATCTCAA
GCGCGCCATGGAGATCGCCGAGTGGAAAGATTTTTCCAAGCGCGCCAAGGCCGCCAAGAAGAATGGCCTCGTCCGCGGCA
TCGGGCTGGCCAGCTATGTCGAGGTCTGCGGCACGATGGGCGAGGAGACCGCCCATGTGAAGCTCGATCCCAATGGCGAT
GTGACGATCCTGATCGGCACGCAGTCGAGCGGGCAGGGTCATCAGACGGCCTATGCCCAGATCGTCGCCGAGCAGTTCGG
CCTGCCGCCGGAGCGCGTGCACATCCACCAGGGCGACACCGCGCAGGTTCCGACGGGGCTCGGCACCGGCGGCTCGGCTT
CGATTCCCTCGGGCGGCGTCAGCGTGCAGCGCGCCACCCATGAGCTCGGCGATAAGCTCAAGCAGATCGCGGCCGAAGCG
CTCGAAGCGGGCTTGGGCGACCTCGAGATCGCCGACGGCGTGATCCGCGTCGCCGGCACCGACCGGTCGATCACCTTCGC
CGATCTCGCCAAGCGGCCCGGCGTCGATCCGGCCAAGCTCAACGGCAGCGCCACCTTCGCCAGCGCCGACGGCACCTATC
CGAACGGCACGCATGTCGCTGAGATCGAGCTCGATCCGGCCACCGGCATTATCAGAATCGTGAACTACGTGATCGTCGAC
GATTTTGGCGTGACGCTGAACCCGCTGCTGCTCGCCGGCCAGGTGCATGGCGGCGCGGTGCAGGGCATCGGTCAGGCGTT
GATGGAGCAGGTGGTCTACAGCAACTCGGATGCGCAGCTTGTCACCGGCAGCTACATGGACTACGCGCTGCCGCGCGCCG
CGGACGCGCCGTCCTTCACCTTCGAGACCCACAACGTGCCCTGCAAGACCAATCCGATGGGCGTCAAGGGCGCGGGCGAG
GCGGGCGCGATCGGCTCCTGTCCGGCGGTGGTCAACGCCGTCGTCGAGGCGCTGTGGCGTGAGTACAAGATCGACCACAT
CGACATGCCGGCGACGCCCGAGCGGGTCTGGATCGCGATCCGGGAGCAGCACCGCCGTCACAGTCTCTGA

Upstream 100 bases:

>100_bases
CGATCGTGTCCCCCTGCGGCGGAGTTGCCGTTTGCGCGAGGCCTCGTTCCGCTGCAATATGGCGCCAACATCGCCAAAAC
GAAGTGGGACGTGAAACCAG

Downstream 100 bases:

>100_bases
ATACTGTTTCCCAAACACTCTCGGATAACCGCCTCAATTGCGGAATAACCCGCCGACTGAGGGGTTGACCAACCAGGCGC
GACCCGTCCAGGTGGGCTGG

Product: putative aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding protein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 769; Mature: 768

Protein sequence:

>769_residues
MAAPIKFGMGQSVLRKEDDALIRGKGRYTDDLAPSAALHALVLRSPQAHAKFTIDVSAARLLPGVALILTAEDTAELGGL
PCLFNLETDPFTAPPYPILAKDEVRHVGDAVAFVVADTLDHARDALEAIKVEWTTLPAVTGVVNAIKPGAPQVWPDHKGN
VLFDVSIGDKAATEAAFAKAHAVAEIRIVNPRVVASFMETRAAVCEYDTKRDHLTLTAGSQGSHRLRDILCQNVLKIPTE
KMRVICPDVGGGFGTKLFPYREYALVAVAAQRLRKSVRWAADRSEHFMGDAQGRDNVTTARMALAEDGKFLAMDVDLMGD
MGAYLSTFAPYIPHGGAGMLPGLYDIQKFHCRVRTIFTHTVPVDAYRGAGRPEAAYVVERLVDACARKLDMSVDAIRRKN
FIPPRALPYKTATGKVYDSGDFNAHLKRAMEIAEWKDFSKRAKAAKKNGLVRGIGLASYVEVCGTMGEETAHVKLDPNGD
VTILIGTQSSGQGHQTAYAQIVAEQFGLPPERVHIHQGDTAQVPTGLGTGGSASIPSGGVSVQRATHELGDKLKQIAAEA
LEAGLGDLEIADGVIRVAGTDRSITFADLAKRPGVDPAKLNGSATFASADGTYPNGTHVAEIELDPATGIIRIVNYVIVD
DFGVTLNPLLLAGQVHGGAVQGIGQALMEQVVYSNSDAQLVTGSYMDYALPRAADAPSFTFETHNVPCKTNPMGVKGAGE
AGAIGSCPAVVNAVVEALWREYKIDHIDMPATPERVWIAIREQHRRHSL

Sequences:

>Translated_769_residues
MAAPIKFGMGQSVLRKEDDALIRGKGRYTDDLAPSAALHALVLRSPQAHAKFTIDVSAARLLPGVALILTAEDTAELGGL
PCLFNLETDPFTAPPYPILAKDEVRHVGDAVAFVVADTLDHARDALEAIKVEWTTLPAVTGVVNAIKPGAPQVWPDHKGN
VLFDVSIGDKAATEAAFAKAHAVAEIRIVNPRVVASFMETRAAVCEYDTKRDHLTLTAGSQGSHRLRDILCQNVLKIPTE
KMRVICPDVGGGFGTKLFPYREYALVAVAAQRLRKSVRWAADRSEHFMGDAQGRDNVTTARMALAEDGKFLAMDVDLMGD
MGAYLSTFAPYIPHGGAGMLPGLYDIQKFHCRVRTIFTHTVPVDAYRGAGRPEAAYVVERLVDACARKLDMSVDAIRRKN
FIPPRALPYKTATGKVYDSGDFNAHLKRAMEIAEWKDFSKRAKAAKKNGLVRGIGLASYVEVCGTMGEETAHVKLDPNGD
VTILIGTQSSGQGHQTAYAQIVAEQFGLPPERVHIHQGDTAQVPTGLGTGGSASIPSGGVSVQRATHELGDKLKQIAAEA
LEAGLGDLEIADGVIRVAGTDRSITFADLAKRPGVDPAKLNGSATFASADGTYPNGTHVAEIELDPATGIIRIVNYVIVD
DFGVTLNPLLLAGQVHGGAVQGIGQALMEQVVYSNSDAQLVTGSYMDYALPRAADAPSFTFETHNVPCKTNPMGVKGAGE
AGAIGSCPAVVNAVVEALWREYKIDHIDMPATPERVWIAIREQHRRHSL
>Mature_768_residues
AAPIKFGMGQSVLRKEDDALIRGKGRYTDDLAPSAALHALVLRSPQAHAKFTIDVSAARLLPGVALILTAEDTAELGGLP
CLFNLETDPFTAPPYPILAKDEVRHVGDAVAFVVADTLDHARDALEAIKVEWTTLPAVTGVVNAIKPGAPQVWPDHKGNV
LFDVSIGDKAATEAAFAKAHAVAEIRIVNPRVVASFMETRAAVCEYDTKRDHLTLTAGSQGSHRLRDILCQNVLKIPTEK
MRVICPDVGGGFGTKLFPYREYALVAVAAQRLRKSVRWAADRSEHFMGDAQGRDNVTTARMALAEDGKFLAMDVDLMGDM
GAYLSTFAPYIPHGGAGMLPGLYDIQKFHCRVRTIFTHTVPVDAYRGAGRPEAAYVVERLVDACARKLDMSVDAIRRKNF
IPPRALPYKTATGKVYDSGDFNAHLKRAMEIAEWKDFSKRAKAAKKNGLVRGIGLASYVEVCGTMGEETAHVKLDPNGDV
TILIGTQSSGQGHQTAYAQIVAEQFGLPPERVHIHQGDTAQVPTGLGTGGSASIPSGGVSVQRATHELGDKLKQIAAEAL
EAGLGDLEIADGVIRVAGTDRSITFADLAKRPGVDPAKLNGSATFASADGTYPNGTHVAEIELDPATGIIRIVNYVIVDD
FGVTLNPLLLAGQVHGGAVQGIGQALMEQVVYSNSDAQLVTGSYMDYALPRAADAPSFTFETHNVPCKTNPMGVKGAGEA
GAIGSCPAVVNAVVEALWREYKIDHIDMPATPERVWIAIREQHRRHSL

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=778, Percent_Identity=25.4498714652956, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI91823271, Length=784, Percent_Identity=23.9795918367347, Blast_Score=137, Evalue=3e-32,
Organism=Escherichia coli, GI1789230, Length=760, Percent_Identity=28.0263157894737, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI1789246, Length=809, Percent_Identity=24.9690976514215, Blast_Score=198, Evalue=1e-51,
Organism=Escherichia coli, GI1786478, Length=737, Percent_Identity=24.8303934871099, Blast_Score=118, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=780, Percent_Identity=23.3333333333333, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17539860, Length=762, Percent_Identity=24.0157480314961, Blast_Score=129, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI32566215, Length=551, Percent_Identity=23.956442831216, Blast_Score=116, Evalue=5e-26,
Organism=Drosophila melanogaster, GI17737937, Length=735, Percent_Identity=26.2585034013605, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24647199, Length=780, Percent_Identity=21.7948717948718, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24647193, Length=714, Percent_Identity=23.249299719888, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24647201, Length=744, Percent_Identity=21.2365591397849, Blast_Score=79, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 82345; Mature: 82214

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPIKFGMGQSVLRKEDDALIRGKGRYTDDLAPSAALHALVLRSPQAHAKFTIDVSAAR
CCCCCCCCCCHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEHHHH
LLPGVALILTAEDTAELGGLPCLFNLETDPFTAPPYPILAKDEVRHVGDAVAFVVADTLD
HCCCEEEEEEECCHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
HARDALEAIKVEWTTLPAVTGVVNAIKPGAPQVWPDHKGNVLFDVSIGDKAATEAAFAKA
HHHHHHHHHEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHH
HAVAEIRIVNPRVVASFMETRAAVCEYDTKRDHLTLTAGSQGSHRLRDILCQNVLKIPTE
HEEEEEEEECHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCC
KMRVICPDVGGGFGTKLFPYREYALVAVAAQRLRKSVRWAADRSEHFMGDAQGRDNVTTA
CEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHH
RMALAEDGKFLAMDVDLMGDMGAYLSTFAPYIPHGGAGMLPGLYDIQKFHCRVRTIFTHT
HHHHHCCCCEEEEEEHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHEEEEEEEEEE
VPVDAYRGAGRPEAAYVVERLVDACARKLDMSVDAIRRKNFIPPRALPYKTATGKVYDSG
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCEEECC
DFNAHLKRAMEIAEWKDFSKRAKAAKKNGLVRGIGLASYVEVCGTMGEETAHVKLDPNGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHCCCCCCEEEEECCCCC
VTILIGTQSSGQGHQTAYAQIVAEQFGLPPERVHIHQGDTAQVPTGLGTGGSASIPSGGV
EEEEEECCCCCCCCHHHHHHHHHHHHCCCHHEEEEECCCCCCCCCCCCCCCCCCCCCCCC
SVQRATHELGDKLKQIAAEALEAGLGDLEIADGVIRVAGTDRSITFADLAKRPGVDPAKL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEECCCCCEEHHHHHHCCCCCHHHC
NGSATFASADGTYPNGTHVAEIELDPATGIIRIVNYVIVDDFGVTLNPLLLAGQVHGGAV
CCCEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHEECCCCCCCCEEEEECCCCHHH
QGIGQALMEQVVYSNSDAQLVTGSYMDYALPRAADAPSFTFETHNVPCKTNPMGVKGAGE
HHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCC
AGAIGSCPAVVNAVVEALWREYKIDHIDMPATPERVWIAIREQHRRHSL
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEHHHHHHHHHCCC
>Mature Secondary Structure 
AAPIKFGMGQSVLRKEDDALIRGKGRYTDDLAPSAALHALVLRSPQAHAKFTIDVSAAR
CCCCCCCCCHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEHHHH
LLPGVALILTAEDTAELGGLPCLFNLETDPFTAPPYPILAKDEVRHVGDAVAFVVADTLD
HCCCEEEEEEECCHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
HARDALEAIKVEWTTLPAVTGVVNAIKPGAPQVWPDHKGNVLFDVSIGDKAATEAAFAKA
HHHHHHHHHEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHH
HAVAEIRIVNPRVVASFMETRAAVCEYDTKRDHLTLTAGSQGSHRLRDILCQNVLKIPTE
HEEEEEEEECHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCC
KMRVICPDVGGGFGTKLFPYREYALVAVAAQRLRKSVRWAADRSEHFMGDAQGRDNVTTA
CEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHH
RMALAEDGKFLAMDVDLMGDMGAYLSTFAPYIPHGGAGMLPGLYDIQKFHCRVRTIFTHT
HHHHHCCCCEEEEEEHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHEEEEEEEEEE
VPVDAYRGAGRPEAAYVVERLVDACARKLDMSVDAIRRKNFIPPRALPYKTATGKVYDSG
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCEEECC
DFNAHLKRAMEIAEWKDFSKRAKAAKKNGLVRGIGLASYVEVCGTMGEETAHVKLDPNGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHCCCCCCEEEEECCCCC
VTILIGTQSSGQGHQTAYAQIVAEQFGLPPERVHIHQGDTAQVPTGLGTGGSASIPSGGV
EEEEEECCCCCCCCHHHHHHHHHHHHCCCHHEEEEECCCCCCCCCCCCCCCCCCCCCCCC
SVQRATHELGDKLKQIAAEALEAGLGDLEIADGVIRVAGTDRSITFADLAKRPGVDPAKL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEECCCCCEEHHHHHHCCCCCHHHC
NGSATFASADGTYPNGTHVAEIELDPATGIIRIVNYVIVDDFGVTLNPLLLAGQVHGGAV
CCCEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHEECCCCCCCCEEEEECCCCHHH
QGIGQALMEQVVYSNSDAQLVTGSYMDYALPRAADAPSFTFETHNVPCKTNPMGVKGAGE
HHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCC
AGAIGSCPAVVNAVVEALWREYKIDHIDMPATPERVWIAIREQHRRHSL
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]