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The map label for this gene is msrB [H]

Identifier: 146341931

GI number: 146341931

Start: 5259559

End: 5260062

Strand: Reverse

Name: msrB [H]

Synonym: BRADO5066

Alternate gene names: 146341931

Gene position: 5260062-5259559 (Counterclockwise)

Preceding gene: 146341932

Following gene: 146341930

Centisome position: 70.54

GC content: 67.46

Gene sequence:

>504_bases
ATGATCGATCGACGCATGATGCTCACGACCACAGCCGGACTGTTCGGCTTCGCCGCCCTGCGCTGGTTCGGCGGCTCCGC
GCCCGCCCGCGCCGCCGAAAAATTCGAGATCGAGAAGACCGAAGCGGAGTGGCGCGCCCAGCTGACGCCGGAGCAGTTCG
ACATCCTGCGCAAGGAAGGCACCGAGCGGCCCTGGACCAGCCCGTTGTTGAAGGAGCACCGCAAGGGCACCTTCGCCTGC
GCCGGCTGCGACCTGCCGCTGTTCTCCTCCGAGACCAAGTTCGACAGCGGCACCGGCTGGCCGAGCTTCTTCAAGCCGCT
CGACAACGCCGTGGGCACCCGCCAGGACAAGACCTACGGCATGGTTCGCACCGAGGTGCATTGCCGGCGCTGCGGCGGCC
ATCTCGGCCACGTGTTCGACGACGGCCCGAAGCCGACTGGCCTGCGCTACTGCATGGACGGCCTGTCGCTGGTGTTCCAT
CCGGCCAGCCAATCCTCGACCTGA

Upstream 100 bases:

>100_bases
GGCTAGCTCGCAAGAAAGTGAGGCGTCGGGCGCGGACCCGGCGTAACTTGGTGCAATCTCATCCGTAAATCCGGTAATCC
CTGTCGTACGGAGACCAGAG

Downstream 100 bases:

>100_bases
CGAAAATTGTCCGCCTGGATTGGCCAGCGCGTCCGTTGAAGATCTGAAAAGCGGGTCTTGAGGACGCGCCGGCGCCTGCT
TGCAGCAGTGGAGCCGGAGC

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MIDRRMMLTTTAGLFGFAALRWFGGSAPARAAEKFEIEKTEAEWRAQLTPEQFDILRKEGTERPWTSPLLKEHRKGTFAC
AGCDLPLFSSETKFDSGTGWPSFFKPLDNAVGTRQDKTYGMVRTEVHCRRCGGHLGHVFDDGPKPTGLRYCMDGLSLVFH
PASQSST

Sequences:

>Translated_167_residues
MIDRRMMLTTTAGLFGFAALRWFGGSAPARAAEKFEIEKTEAEWRAQLTPEQFDILRKEGTERPWTSPLLKEHRKGTFAC
AGCDLPLFSSETKFDSGTGWPSFFKPLDNAVGTRQDKTYGMVRTEVHCRRCGGHLGHVFDDGPKPTGLRYCMDGLSLVFH
PASQSST
>Mature_167_residues
MIDRRMMLTTTAGLFGFAALRWFGGSAPARAAEKFEIEKTEAEWRAQLTPEQFDILRKEGTERPWTSPLLKEHRKGTFAC
AGCDLPLFSSETKFDSGTGWPSFFKPLDNAVGTRQDKTYGMVRTEVHCRRCGGHLGHVFDDGPKPTGLRYCMDGLSLVFH
PASQSST

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=152, Percent_Identity=42.7631578947368, Blast_Score=130, Evalue=6e-31,
Organism=Homo sapiens, GI301336162, Length=152, Percent_Identity=42.7631578947368, Blast_Score=130, Evalue=6e-31,
Organism=Homo sapiens, GI73089054, Length=152, Percent_Identity=42.7631578947368, Blast_Score=130, Evalue=6e-31,
Organism=Homo sapiens, GI37620216, Length=143, Percent_Identity=42.6573426573427, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI117606353, Length=134, Percent_Identity=44.0298507462687, Blast_Score=123, Evalue=8e-29,
Organism=Escherichia coli, GI1788077, Length=118, Percent_Identity=47.4576271186441, Blast_Score=123, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17553450, Length=134, Percent_Identity=39.5522388059701, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI115532676, Length=134, Percent_Identity=39.5522388059701, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6319816, Length=133, Percent_Identity=39.8496240601504, Blast_Score=105, Evalue=3e-24,
Organism=Drosophila melanogaster, GI221378662, Length=137, Percent_Identity=45.2554744525547, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI221378664, Length=130, Percent_Identity=47.6923076923077, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24645799, Length=141, Percent_Identity=42.5531914893617, Blast_Score=123, Evalue=4e-29,
Organism=Drosophila melanogaster, GI45553335, Length=130, Percent_Identity=46.9230769230769, Blast_Score=123, Evalue=6e-29,
Organism=Drosophila melanogaster, GI21356369, Length=130, Percent_Identity=46.9230769230769, Blast_Score=123, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24645801, Length=152, Percent_Identity=39.4736842105263, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24645804, Length=141, Percent_Identity=43.2624113475177, Blast_Score=118, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 18651; Mature: 18651

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDRRMMLTTTAGLFGFAALRWFGGSAPARAAEKFEIEKTEAEWRAQLTPEQFDILRKEG
CCCCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHCCCHHHHHHHHHCC
TERPWTSPLLKEHRKGTFACAGCDLPLFSSETKFDSGTGWPSFFKPLDNAVGTRQDKTYG
CCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHH
MVRTEVHCRRCGGHLGHVFDDGPKPTGLRYCMDGLSLVFHPASQSST
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHEECCCCCCCC
>Mature Secondary Structure
MIDRRMMLTTTAGLFGFAALRWFGGSAPARAAEKFEIEKTEAEWRAQLTPEQFDILRKEG
CCCCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHCCCHHHHHHHHHCC
TERPWTSPLLKEHRKGTFACAGCDLPLFSSETKFDSGTGWPSFFKPLDNAVGTRQDKTYG
CCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHH
MVRTEVHCRRCGGHLGHVFDDGPKPTGLRYCMDGLSLVFHPASQSST
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]