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The map label for this gene is zraS [C]

Identifier: 146341889

GI number: 146341889

Start: 5211388

End: 5213919

Strand: Reverse

Name: zraS [C]

Synonym: BRADO5023

Alternate gene names: 146341889

Gene position: 5213919-5211388 (Counterclockwise)

Preceding gene: 146341890

Following gene: 146341888

Centisome position: 69.92

GC content: 67.34

Gene sequence:

>2532_bases
GTGAACCTGCCGGAGCGGCCGCGCCGCAGCGGCAGCATCCTGCTGATCCTGCTGGTGGCGTTCGGCCTCGTCGCGGTCGC
GATCGCGCTGATGACGATCGGCCGCAACCAGGCGCAGCCCTATATTCTCGGCCTGCTGTCGCTGCTCGCCACCGTCGGCC
TGTTCAACCTGTTCGCCTTCGCTGCCGGCATCGTCCGCTTCGCCGACAAGGCGGCCGACGATCCCGTCATGGGCGCGATC
GCCGATCACGCCTTCGACGGGCTCGCAGTGACCGATCCGCGCGGGCATGTGGTCTATGCCAACGCGGCCTATCTGAGCAT
GACCGGGGCGGCCAGCGCTCAGGAGGCGCGCCCCGTGGAGCGCGTCTTCATCGGCAATCCCGACGTCTCCGAGGCCGTAT
TCCGCCTGTTGAAAGCGGCGCGCGAGGGCAAGCGGCAGCAGGAGGAGGTGCGCATCACCGCCTCCGAGGGCGGCCAGGGC
CGCTGGCTGCGCATGCGGGTGCGCCCGCTCGGCCAGACCAAGCGCTATCAGCGCTACGCCGTGTGGTCGATCGCTGACAT
CACAAGGGATCGCGAGCGCCAGGAGGACGTGTTCCAGGAGCTCCAGCATGCCATCGAATATCTCGACCATGCGCCCTGCG
GCTTTTTCTCGGTCAATCCGGAAGGCGGCCTCGTCTACGTCAACGCCACGCTCGCCAACTGGCTCGACTATGATCTCGCC
GAGATCGGCTCCGGCGGATTGAAACTCGCCGACGTCGTCTCCGGCGACGGCGCATCGCTGCTGACCTCGATCGTCGCGGT
GCCCGGCGAGGTCCGCACCGAGGTGTTCGACATCGACCTGAAGATGCGCGGCGGCAAGACCATGCCGGCGCGGCTCTATC
ACAAGCTCGCCTTCGGCGCCGACGGCAAGCCGGGCGCCTCGCGCACCCTGGTCATCAGCCGCGCCCGCGACGAGCGCTCC
GATCCGGAGCGCGCCGCCGAGGTGCGCTTCATGCGCTTCTTCGACCACACGCCGATGGCGATCGCGACCGTCGACCGCGG
CGGCGCCGTGGTCCGCGCCAACGCGCGCTACGCCAAGCTGGCGCAGAGCGTGAGCGGCGACGTGGCCGCGGCGAAATCGA
TCTTCCGCGCCGTCAGCCAGCGCGACCGCCACCTGCTGATCGCTGCGATCAACCAGGCCGCCGAAGGGCAGGCGGACATC
CCGCCGGTCGAGGTCATGCTTGAGGGCGCGAGAGAGCGCTTCGGCCAGTTCTTCGTCACCGCGGTCGACGAGGACGAGCG
CGAGACGGAAGCCGCGATCGTCTATCTGCTCGAGACCACCGAGCGGCGGGCGCTGGAGAACCAGATCAACCAGTCGCAGA
AGATGGAGATGGTCGGCCAGCTCGCCGGCGGCATCGCCCACGACTTCAACAACGTGCTCTCGGCCATCATGATGGCCAAT
GACTTCCTGCTGAACGCGCACAAGCCGACCGACCCGTCGTTCCAGGACATCATGCAGATCAAGCAGAACGCGACGCGCGC
CGCGACGCTGGTGCGGCAGCTGCTGGCGTTCTCGCGCCGCCAGACCCTGCGGCCGCAGGTGCTCGATCTCGGCGATGCGC
TGTCGGATCTGACGATGCTCTTGCGCCGGCTGATCGGCGAGAAGGTCAAGCTCGACCTCAGCCACGGCCGCGACCTCTGG
CCGGTCAAGGTCGACGTCTCGCAGTTCGAGCAGGTGATCGTGAACCTCGCCGTCAACGCCCGCGACGCGATGCCGGATGG
CGGCAAGCTCTCGGTGCGCACCGCCAATGTGACGGCCGAGGAGACGGCGCAGGCGGCCTACAAGGGCATGCCGGTCGCCG
ACTACGTCAAGATCGAGATCAGCGACACCGGAACCGGCATTCCCGCAGAAATTCGCGAGAAGATCTTCGAGCCGTTCTTC
TCGACCAAGGAGGTCGGCAAGGGCACGGGTCTCGGCCTGTCGACCGTCTACGGCATCATCAAGCAGACCGGCGGCTTCAT
CTATGTCGACAGCGAGGTCGGCAAGGGCACCGCATTCCAGATCTTCCTGCCGCGCCATATCGTCGTGCCCGAGGTCCAGC
CCGAGCCGCAGGCGACCAACGGCGGGCCCAAGGAAGCGGCTCCTGCCGCCGAGGCGCCGAAGCCGCGCGCGGATCTGACC
GGGCAGGGCACCATCCTGCTGGTCGAGGACGAGGAGGGCCTGAGGGCGCTGAACGCGCGCGGCCTGCGCTCGCGCGGCTA
CAGCGTCATCGAGGCCTCCAACGGCATCGAGGCGATGGAGGCGCTGGAGGAATGCAACGGCGAGCTCGATCTCGTGGTGT
CCGACGTGGTGATGCCGGAGATGGACGGGCCGACGCTGCTGAAGGTGATGCGCGAGAAGAACCCCGACATCAAGATCATC
TTCGTGTCGGGCTATGCCGAGGACGCCTTCGAGAAGAGCCTGCCGGAGAACCAGCAATTCGCCTTTCTGCCAAAACCCTT
CACGCTCAGTCAGCTGGTGGCGGCGGTGAAGGAAACCATGGCGCCGCAATAG

Upstream 100 bases:

>100_bases
TGGGAGCGGGAGCCGCGTGAACGGGCTGGGGCTCCCAGCCGACAGGTCGCGTCCTCGAGCCATGAGCGCCGATACAGACA
ACGAAGCGTCACCGGACCAG

Downstream 100 bases:

>100_bases
GTTACCAGAAGAGCCGGACAAGGCGGGCGAGCGGCTTGAAGCCGCGACCCAGAGCCGCAGCCGCGCGGCCTCGTGCCGCC
TTCCTTTTCGGCCCGAAGTG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 843; Mature: 843

Protein sequence:

>843_residues
MNLPERPRRSGSILLILLVAFGLVAVAIALMTIGRNQAQPYILGLLSLLATVGLFNLFAFAAGIVRFADKAADDPVMGAI
ADHAFDGLAVTDPRGHVVYANAAYLSMTGAASAQEARPVERVFIGNPDVSEAVFRLLKAAREGKRQQEEVRITASEGGQG
RWLRMRVRPLGQTKRYQRYAVWSIADITRDRERQEDVFQELQHAIEYLDHAPCGFFSVNPEGGLVYVNATLANWLDYDLA
EIGSGGLKLADVVSGDGASLLTSIVAVPGEVRTEVFDIDLKMRGGKTMPARLYHKLAFGADGKPGASRTLVISRARDERS
DPERAAEVRFMRFFDHTPMAIATVDRGGAVVRANARYAKLAQSVSGDVAAAKSIFRAVSQRDRHLLIAAINQAAEGQADI
PPVEVMLEGARERFGQFFVTAVDEDERETEAAIVYLLETTERRALENQINQSQKMEMVGQLAGGIAHDFNNVLSAIMMAN
DFLLNAHKPTDPSFQDIMQIKQNATRAATLVRQLLAFSRRQTLRPQVLDLGDALSDLTMLLRRLIGEKVKLDLSHGRDLW
PVKVDVSQFEQVIVNLAVNARDAMPDGGKLSVRTANVTAEETAQAAYKGMPVADYVKIEISDTGTGIPAEIREKIFEPFF
STKEVGKGTGLGLSTVYGIIKQTGGFIYVDSEVGKGTAFQIFLPRHIVVPEVQPEPQATNGGPKEAAPAAEAPKPRADLT
GQGTILLVEDEEGLRALNARGLRSRGYSVIEASNGIEAMEALEECNGELDLVVSDVVMPEMDGPTLLKVMREKNPDIKII
FVSGYAEDAFEKSLPENQQFAFLPKPFTLSQLVAAVKETMAPQ

Sequences:

>Translated_843_residues
MNLPERPRRSGSILLILLVAFGLVAVAIALMTIGRNQAQPYILGLLSLLATVGLFNLFAFAAGIVRFADKAADDPVMGAI
ADHAFDGLAVTDPRGHVVYANAAYLSMTGAASAQEARPVERVFIGNPDVSEAVFRLLKAAREGKRQQEEVRITASEGGQG
RWLRMRVRPLGQTKRYQRYAVWSIADITRDRERQEDVFQELQHAIEYLDHAPCGFFSVNPEGGLVYVNATLANWLDYDLA
EIGSGGLKLADVVSGDGASLLTSIVAVPGEVRTEVFDIDLKMRGGKTMPARLYHKLAFGADGKPGASRTLVISRARDERS
DPERAAEVRFMRFFDHTPMAIATVDRGGAVVRANARYAKLAQSVSGDVAAAKSIFRAVSQRDRHLLIAAINQAAEGQADI
PPVEVMLEGARERFGQFFVTAVDEDERETEAAIVYLLETTERRALENQINQSQKMEMVGQLAGGIAHDFNNVLSAIMMAN
DFLLNAHKPTDPSFQDIMQIKQNATRAATLVRQLLAFSRRQTLRPQVLDLGDALSDLTMLLRRLIGEKVKLDLSHGRDLW
PVKVDVSQFEQVIVNLAVNARDAMPDGGKLSVRTANVTAEETAQAAYKGMPVADYVKIEISDTGTGIPAEIREKIFEPFF
STKEVGKGTGLGLSTVYGIIKQTGGFIYVDSEVGKGTAFQIFLPRHIVVPEVQPEPQATNGGPKEAAPAAEAPKPRADLT
GQGTILLVEDEEGLRALNARGLRSRGYSVIEASNGIEAMEALEECNGELDLVVSDVVMPEMDGPTLLKVMREKNPDIKII
FVSGYAEDAFEKSLPENQQFAFLPKPFTLSQLVAAVKETMAPQ
>Mature_843_residues
MNLPERPRRSGSILLILLVAFGLVAVAIALMTIGRNQAQPYILGLLSLLATVGLFNLFAFAAGIVRFADKAADDPVMGAI
ADHAFDGLAVTDPRGHVVYANAAYLSMTGAASAQEARPVERVFIGNPDVSEAVFRLLKAAREGKRQQEEVRITASEGGQG
RWLRMRVRPLGQTKRYQRYAVWSIADITRDRERQEDVFQELQHAIEYLDHAPCGFFSVNPEGGLVYVNATLANWLDYDLA
EIGSGGLKLADVVSGDGASLLTSIVAVPGEVRTEVFDIDLKMRGGKTMPARLYHKLAFGADGKPGASRTLVISRARDERS
DPERAAEVRFMRFFDHTPMAIATVDRGGAVVRANARYAKLAQSVSGDVAAAKSIFRAVSQRDRHLLIAAINQAAEGQADI
PPVEVMLEGARERFGQFFVTAVDEDERETEAAIVYLLETTERRALENQINQSQKMEMVGQLAGGIAHDFNNVLSAIMMAN
DFLLNAHKPTDPSFQDIMQIKQNATRAATLVRQLLAFSRRQTLRPQVLDLGDALSDLTMLLRRLIGEKVKLDLSHGRDLW
PVKVDVSQFEQVIVNLAVNARDAMPDGGKLSVRTANVTAEETAQAAYKGMPVADYVKIEISDTGTGIPAEIREKIFEPFF
STKEVGKGTGLGLSTVYGIIKQTGGFIYVDSEVGKGTAFQIFLPRHIVVPEVQPEPQATNGGPKEAAPAAEAPKPRADLT
GQGTILLVEDEEGLRALNARGLRSRGYSVIEASNGIEAMEALEECNGELDLVVSDVVMPEMDGPTLLKVMREKNPDIKII
FVSGYAEDAFEKSLPENQQFAFLPKPFTLSQLVAAVKETMAPQ

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=30.3643724696356, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1788549, Length=279, Percent_Identity=29.3906810035842, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788713, Length=292, Percent_Identity=28.0821917808219, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1790300, Length=247, Percent_Identity=28.7449392712551, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI48994928, Length=240, Percent_Identity=30.8333333333333, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=120, Percent_Identity=30, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786912, Length=283, Percent_Identity=23.6749116607774, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 91900; Mature: 91900

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPERPRRSGSILLILLVAFGLVAVAIALMTIGRNQAQPYILGLLSLLATVGLFNLFAF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AAGIVRFADKAADDPVMGAIADHAFDGLAVTDPRGHVVYANAAYLSMTGAASAQEARPVE
HHHHHHHHHHCCCCCHHHHHHHHCCCCEEEECCCCCEEEECEEEEEECCCCCHHHCCCCC
RVFIGNPDVSEAVFRLLKAAREGKRQQEEVRITASEGGQGRWLRMRVRPLGQTKRYQRYA
EEEECCCCHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCEEEEEECCCCCCHHHHHHH
VWSIADITRDRERQEDVFQELQHAIEYLDHAPCGFFSVNPEGGLVYVNATLANWLDYDLA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEHHHHHHHHHHH
EIGSGGLKLADVVSGDGASLLTSIVAVPGEVRTEVFDIDLKMRGGKTMPARLYHKLAFGA
HHCCCCCEEEEEECCCCHHHHHHHHHCCCHHCEEEEEEEEEECCCCCCHHHHHHHHHCCC
DGKPGASRTLVISRARDERSDPERAAEVRFMRFFDHTPMAIATVDRGGAVVRANARYAKL
CCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCHHHHH
AQSVSGDVAAAKSIFRAVSQRDRHLLIAAINQAAEGQADIPPVEVMLEGARERFGQFFVT
HHHHCCHHHHHHHHHHHHHHCCCEEEEEECCHHCCCCCCCCHHHHHHHHHHHHCCCEEEE
AVDEDERETEAAIVYLLETTERRALENQINQSQKMEMVGQLAGGIAHDFNNVLSAIMMAN
EECCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFLLNAHKPTDPSFQDIMQIKQNATRAATLVRQLLAFSRRQTLRPQVLDLGDALSDLTML
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LRRLIGEKVKLDLSHGRDLWPVKVDVSQFEQVIVNLAVNARDAMPDGGKLSVRTANVTAE
HHHHCCCCEEEECCCCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHH
ETAQAAYKGMPVADYVKIEISDTGTGIPAEIREKIFEPFFSTKEVGKGTGLGLSTVYGII
HHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHHH
KQTGGFIYVDSEVGKGTAFQIFLPRHIVVPEVQPEPQATNGGPKEAAPAAEAPKPRADLT
HHCCCEEEEECCCCCCEEEEEEECCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GQGTILLVEDEEGLRALNARGLRSRGYSVIEASNGIEAMEALEECNGELDLVVSDVVMPE
CCCEEEEEECCCCHHHHHCCCHHHCCCEEEECCCCHHHHHHHHHCCCCEEEEEEHHHCCC
MDGPTLLKVMREKNPDIKIIFVSGYAEDAFEKSLPENQQFAFLPKPFTLSQLVAAVKETM
CCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHH
APQ
CCC
>Mature Secondary Structure
MNLPERPRRSGSILLILLVAFGLVAVAIALMTIGRNQAQPYILGLLSLLATVGLFNLFAF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AAGIVRFADKAADDPVMGAIADHAFDGLAVTDPRGHVVYANAAYLSMTGAASAQEARPVE
HHHHHHHHHHCCCCCHHHHHHHHCCCCEEEECCCCCEEEECEEEEEECCCCCHHHCCCCC
RVFIGNPDVSEAVFRLLKAAREGKRQQEEVRITASEGGQGRWLRMRVRPLGQTKRYQRYA
EEEECCCCHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCEEEEEECCCCCCHHHHHHH
VWSIADITRDRERQEDVFQELQHAIEYLDHAPCGFFSVNPEGGLVYVNATLANWLDYDLA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEHHHHHHHHHHH
EIGSGGLKLADVVSGDGASLLTSIVAVPGEVRTEVFDIDLKMRGGKTMPARLYHKLAFGA
HHCCCCCEEEEEECCCCHHHHHHHHHCCCHHCEEEEEEEEEECCCCCCHHHHHHHHHCCC
DGKPGASRTLVISRARDERSDPERAAEVRFMRFFDHTPMAIATVDRGGAVVRANARYAKL
CCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCHHHHH
AQSVSGDVAAAKSIFRAVSQRDRHLLIAAINQAAEGQADIPPVEVMLEGARERFGQFFVT
HHHHCCHHHHHHHHHHHHHHCCCEEEEEECCHHCCCCCCCCHHHHHHHHHHHHCCCEEEE
AVDEDERETEAAIVYLLETTERRALENQINQSQKMEMVGQLAGGIAHDFNNVLSAIMMAN
EECCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFLLNAHKPTDPSFQDIMQIKQNATRAATLVRQLLAFSRRQTLRPQVLDLGDALSDLTML
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LRRLIGEKVKLDLSHGRDLWPVKVDVSQFEQVIVNLAVNARDAMPDGGKLSVRTANVTAE
HHHHCCCCEEEECCCCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHH
ETAQAAYKGMPVADYVKIEISDTGTGIPAEIREKIFEPFFSTKEVGKGTGLGLSTVYGII
HHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHHH
KQTGGFIYVDSEVGKGTAFQIFLPRHIVVPEVQPEPQATNGGPKEAAPAAEAPKPRADLT
HHCCCEEEEECCCCCCEEEEEEECCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GQGTILLVEDEEGLRALNARGLRSRGYSVIEASNGIEAMEALEECNGELDLVVSDVVMPE
CCCEEEEEECCCCHHHHHCCCHHHCCCEEEECCCCHHHHHHHHHCCCCEEEEEEHHHCCC
MDGPTLLKVMREKNPDIKIIFVSGYAEDAFEKSLPENQQFAFLPKPFTLSQLVAAVKETM
CCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHH
APQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA